Subtype of: Adrenal gland neoplasms

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
adrenal cortex carcinoma	MONDO_0006639	CIITA	Unknown	24747642	Open Targets	Antigen processing and presentation Toxoplasmosis Tuberculosis +3 more
		CNBD1	Unknown	24747642	Open Targets	—
		COL1A1	Unknown	25743702	Open Targets	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +26 more
		COL3A1	Unknown	24747642	Open Targets	Platelet activation Cytoskeleton in muscle cells Relaxin signaling pathway +16 more
		CREBBP	Unknown	30113656 33148256 28481359	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +52 more
		CRLF2	Unknown	28481359	Open Targets	Cytokine-cytokine receptor interaction JAK-STAT signaling pathway Interleukin-7 signaling
		CSF1R	Unknown	24747642 30113656 33148256	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +10 more
		CTNNA1	Unknown	33148256	Open Targets	Hippo signaling pathway Adherens junction Leukocyte transendothelial migration +9 more
		CTNND2	Unknown	25743702	Open Targets	Wnt signaling pathway
		CUL3	Unknown	24747642	Open Targets	Ubiquitin mediated proteolysis Hedgehog signaling pathway Degradation of DVL +4 more
		CUX1	Unknown	33148256	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Intra-Golgi traffic
		CYP2C8	Unknown	24747642	Open Targets	Arachidonic acid metabolism Linoleic acid metabolism Retinol metabolism +10 more
		DAXX	Unknown	24747642 30113656 28481359 25078331	Open Targets	MAPK signaling pathway Apoptosis Parkinson disease +6 more
		DCAF12L2	Unknown	25743702	Open Targets	—
		DCC	Unknown	24747642	Open Targets	Axon guidance Pathways in cancer Colorectal cancer +3 more
		DNM2	Unknown	24747642	Open Targets	Phospholipase D signaling pathway Endocytosis Fc gamma R-mediated phagocytosis +13 more
		DNMT3A	Unknown	30113656 25078331	Open Targets	Cysteine and methionine metabolism Metabolic pathways Efferocytosis +3 more
		EED	Unknown	28481359	Open Targets	Polycomb repressive complex PRC2 methylates histones and DNA Oxidative Stress Induced Senescence +4 more
		EGFR	Unknown	30113656 25078331 23585556 24747642 19190079 28481359 23139256	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Virion - Hepatitis viruses +79 more
		ELL	Unknown	24747642	Open Targets	Viral life cycle - HIV-1 Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events +4 more
		EP300	Unknown	30113656 33148256 25743702 25078331	Open Targets	Polycomb repressive complex Viral life cycle - HIV-1 cAMP signaling pathway +66 more
		EPHA3	Unknown	33148256	Open Targets	Axon guidance EPH-Ephrin signaling EPHA-mediated growth cone collapse +1 more
		EPHA7	Unknown	28481359	Open Targets	Axon guidance EPH-Ephrin signaling EPHA-mediated growth cone collapse +1 more
		ERBB3	Unknown	33148256	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway ErbB signaling pathway +19 more
		ERBB4	Unknown	33148256	Open Targets	MAPK signaling pathway ErbB signaling pathway Calcium signaling pathway +22 more
		ERCC2	Unknown	24747642	Open Targets	Basal transcription factors Nucleotide excision repair Formation of RNA Pol II elongation complex +19 more
		ERCC4	Unknown	24747642	Open Targets	Nucleotide excision repair Fanconi anemia pathway HDR through Single Strand Annealing (SSA) +4 more
		ESR1	Unknown	30113656	Open Targets	Endocrine resistance Hormone signaling Estrogen signaling pathway +21 more
		ETV5	Unknown	24747642	Open Targets	Transcriptional misregulation in cancer Prostate cancer
		EXT2	Unknown	25743702	Open Targets	Glycosaminoglycan biosynthesis - heparan sulfate / heparin Metabolic pathways HS-GAG biosynthesis +2 more
		EZH2	Unknown	30113656 33148256	Open Targets	Lysine degradation Metabolic pathways Polycomb repressive complex +7 more
		FANCA	Unknown	24747642 33148256	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FANCE	Unknown	24747642 30113656 33148256	Open Targets	Fanconi anemia pathway Fanconi Anemia Pathway
		FAT1	Unknown	24747642 33148256 28481359	Open Targets	—
		FAT3	Unknown	24747642	Open Targets	—
		FBXO11	Unknown	30113656	Open Targets	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
		FBXW7	Unknown	30113656	Open Targets	Ubiquitin mediated proteolysis Constitutive Signaling by NOTCH1 PEST Domain Mutants Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling +3 more
		FCRL4	Unknown	25743702	Open Targets	—
		FGFR2	Unknown	30113656 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +26 more
		FGFR3	Unknown	33148256	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +27 more
		FLCN	Unknown	30113656	Open Targets	mTOR signaling pathway Renal cell carcinoma Amino acids regulate mTORC1
		FLI1	Unknown	25743702	Open Targets	Transcriptional misregulation in cancer
		FLNA	Unknown	24747642	Open Targets	MAPK signaling pathway Focal adhesion Salmonella infection +6 more
		FLT3	Unknown	28481359	Open Targets	MAPK signaling pathway Ras signaling pathway PI3K-Akt signaling pathway +8 more
		FLT4	Unknown	28481359	Open Targets	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +6 more
		FOXP1	Unknown	24747642	Open Targets	MicroRNAs in cancer Transcriptional regulation of pluripotent stem cells
		GAS7	Unknown	24747642	Open Targets	—
		GATA1	Unknown	28481359 25078331	Open Targets	RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function RUNX1 regulates transcription of genes involved in differentiation of HSCs Factors involved in megakaryocyte development and platelet production
		GNA11	Unknown	30113656	Open Targets	Calcium signaling pathway cGMP-PKG signaling pathway Hormone signaling +23 more
		GNAS	Unknown	30113656 33148256 27296931	Open Targets	Endocrine resistance Rap1 signaling pathway Calcium signaling pathway +58 more

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Adrenal cortex carcinoma

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