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Acute lymphoblastic leukemia
Acute lymphoblastic leukemia
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Pathways column key:
KEGG
Reactome
Disease Term
Disease ID
Gene Symbol
Classification
References
Source
Pathways
All
MONDO_0004967
BLM
Unknown
28297620
Open Targets
Homologous recombination
Fanconi anemia pathway
Processive synthesis on the C-strand of the telomere
SUMOylation of DNA damage response and repair proteins
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint
+10 more
LIG4
Unknown
28297620
Open Targets
Non-homologous end-joining
2-LTR circle formation
Nonhomologous End-Joining (NHEJ)
SH2B3
Unknown
27881370
23908464
27913496
39316992
28484264
Open Targets
Neurotrophin signaling pathway
Regulation of KIT signaling
Factors involved in megakaryocyte development and platelet production
All
3
Causal
0
Unknown
3
Select all
Clear
ClinVar
0
Orphanet
0
Disgenet
0
CTD
0
HPO
0
GWAS catalog
0
GenCC
0
ClinGen
0
Open Targets
3
Related Diseases
Diseases that share the most curated genes with Acute lymphoblastic leukemia.
5
View disease cluster →
Growth retardation, mild developmental delay, chronic hepatitis syndrome
1 shared gene
SH2B3
Related via 1 shared gene including SH2B3.
Dna ligase iv deficiency
1 shared gene
LIG4
Related via 1 shared gene including LIG4.
Myelofibrosis, somatic
1 shared gene
SH2B3
Related via 1 shared gene including SH2B3.
Dubowitz syndrome
1 shared gene
LIG4
Related via 1 shared gene including LIG4.
Lig4 syndrome
1 shared gene
LIG4
Related via 1 shared gene including LIG4.
1
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