Pathways

2-Oxocarboxylic acid metabolism

ABHD14A-ACY1, GOT1L1, CS, NAGS, DBT, DLAT, DLD, DLST, AGXT, GOT1, GOT2, GPT, IDH1, IDH2, IDH3A, IDH3B, IDH3G, ACO1, OGDH, ACO2, AADAT, PDHA1, PDHA2, PDHB, DHTKD1, OGDHL, BCAT1, BCAT2, BCKDHA, BCKDHB, AGXT2, GPT2, ACY1

ABC transporters

ABCC5, ABCB6, ABCC9, ABCC4, ABCA7, ABCA10, ABCA9, ABCA8, CFTR, ABCB8, ABCC2, ABCA13, DEFB1, ABCA1, ABCA2, ABCA3, ABCD1, ABCB7, ABCD2, ABCB10, ABCB9, ABCA6, ABCA5, ABCA4, ABCA12, ABCB5, ABCC6, ABCC1, ABCB1, ABCB4, ABCD3, ABCD4, ABCG4, ABCG5, ABCG8, ABCC8, TAP1, TAP2, ABCC11, ABCB11, ABCC3, ABCC10, ABCC12, ABCG2, ABCG1

Acute myeloid leukemia

AKT3, CEBPA, CEBPE, P3R3URF-PIK3R3, PIM2, CHUK, CSF1R, CSF2, DUSP6, EIF4EBP1, AKT1, AKT2, FCGR1A, FLT3, MTOR, GRB2, HRAS, IKBKB, IL3, ITGAM, ARAF, JUP, KIT, KRAS, MPO, MYC, NFKB1, NRAS, LEF1, PIK3CA, PIK3CB, PIM1, PIK3CD, PIK3R1, PIK3R2, PML, PPARD, MAPK1, MAPK3, MAP2K1, MAP2K2, BAD, RAF1, RARA, CCND1, BCL2A1, RELA, RPS6KB1, RPS6KB2, SOS1, SOS2, SPI1, BRAF, STAT3, STAT5A, STAT5B, TCF7, TCF7L2, ZBTB16, TCF7L1, PIK3R3, IKBKG, RUNX1, RUNX1T1, PER2, CCNA2, CCNA1, CD14

Adherens junction

CDH5, WASF2, MYL12B, MYL9, BAIAP2, SORBS1, MYL12A, WASF3, PDCD10, SSX2IP, CREBBP, CSNK2A1, CSNK2A2, CSNK2B, CTNNA1, CTNNA2, CTNNB1, CTNND1, EGFR, EP300, ERBB2, FER, FGFR1, FYN, NECTIN3, CSNK2A3, CTNNA3, MYLPF, IGF1R, INSR, RHOA, LMO7, SMAD3, SMAD4, MET, AFDN, MYL2, MYL5, LEF1, NLK, ACP1, RASIP1, RADIL, MAPK1, MAPK3, PARD3, SMURF1, HEG1, PTPN1, PTPN6, PTPRB, PTPRF, PTPRJ, PTPRM, NECTIN1, NECTIN2, MYL7, RAC1, RAC2, RAC3, RAP1A, RAP1B, ACTB, ROCK1, SMURF2, SNAI2, SNAI1, SRC, MAP3K7, TCF7, TCF7L2, TGFBR1, TGFBR2, TJP1, ACTG1, VCL, WAS, YES1, ACTN4, NECTIN4, TCF7L1, CCM2, ACTN1, IQGAP1, KRIT1, WASF1, WASL, MYL10, ARHGAP29, ROCK2, FARP2, CDC42, CDH1

Adipocytokine signaling pathway

AKT3, CAMKK2, PPARGC1A, CHUK, CPT1C, CPT1A, CPT1B, AGRP, AKT1, AKT2, ACSL1, ACSL3, ACSL4, ACSBG1, ACSL6, MTOR, G6PC1, APPL1, ACACB, IKBKB, IRS1, JAK2, LEP, LEPR, NFKB1, NFKBIA, NFKBIB, NFKBIE, NPY, PCK1, PCK2, ADIPOR1, PRKAG2, ACSL5, PRKAG3, POMC, PPARA, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKCQ, MAPK8, MAPK9, MAPK10, PTPN11, G6PC2, RELA, RXRA, RXRB, RXRG, SLC2A1, SLC2A4, STAT3, STK11, TNF, TNFRSF1A, TNFRSF1B, TRAF2, ADIPOR2, ACSBG2, IRS4, IKBKG, IRS2, TRADD, SOCS3, G6PC3, ADIPOQ, CD36

Adrenergic signaling in cardiomyocytes

AKT3, -, CACNG3, CACNG2, RAPGEF3, CREB3, ADCY1, ADCY2, ADCY3, RAPGEF4, ADCY5, BVES, ADCY6, ADCY7, ADCY8, ADCY9, CREB1, ATF2, ATF6B, CREM, MAPK14, ADRA1D, PIK3R6, ADRA1B, ADRA1A, CREB3L4, ADRB1, ADRB2, CALML6, AGT, AGTR1, AGTR2, ADCY4, AKT1, AKT2, PLCB1, ATP1B4, PIK3R5, CACNG5, CACNG4, GNAI1, GNAI2, GNAI3, GNAQ, GNAS, PPP2R3B, KCNE1, KCNK2, KCNQ1, MYH6, MYH7, MYL2, MYL3, MYL4, ATF4, ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B1, ATP1B2, ATP1B3, FXYD2, ATP2A1, ATP2A2, ATP2A3, ATP2B1, ATP2B2, ATP2B3, ATP2B4, CALML5, PIK3CG, PLCB2, PLCB3, PLCB4, PLN, PPP1CA, PPP1CB, PPP1CC, PPP2R3C, PPP1R1A, PPP2CA, PPP2CB, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R2B, PPP2R2C, PPP2R3A, PPP2R5A, PPP2R5B, PPP2R5C, PPP2R5D, PPP2R5E, PRKACA, PRKACB, PRKACG, PRKCA, CACNA2D3, PPP2R2D, MAPK1, MAPK3, MAPK11, MAPK13, CACNG8, CACNG7, CACNG6, BCL2, RYR2, MAPK12, SCN1B, SCN4B, SCN5A, SCN7A, POPDC2, POPDC3, CREB3L2, SLC8A2, SLC8A1, SLC8A3, SLC9A1, ACTC1, TNNC1, TNNI3, TNNT2, TPM1, TPM2, TPM3, TPM4, CACNA1C, CACNA1D, CACNA1F, CACNA1S, CACNA2D1, CACNB1, CACNB2, CACNB3, CACNB4, CACNG1, CALM1, CALM2, CALM3, CALML3, CAMK2A, CAMK2B, CAMK2D, CAMK2G, CREB3L3, CREB3L1, CALML4, RPS6KA5, CACNA2D2, CACNA2D4, CREB5

African trypanosomiasis

-, IDO2, F2RL1, PLCB1, GNAQ, HBA1, HBA2, HBB, HPR, APOA1, ICAM1, IFNG, FAS, IL1B, FASLG, IL6, IL10, IL12A, IL12B, IL18, IDO1, KNG1, LAMA4, MYD88, NPPA, PLCB2, PLCB3, PLCB4, TLR9, PRKCA, PRKCB, PRKCG, SELE, THOP1, TNF, VCAM1, APOL1

AGE-RAGE signaling pathway in diabetic complications

AKT3, CDK4, CDKN1B, P3R3URF-PIK3R3, PLCD3, COL1A1, COL1A2, COL3A1, COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6, MAPK14, CYBB, DIAPH1, AGER, AGT, AGTR1, EDN1, EGR1, AKT1, AKT2, F3, VEGFD, FOXO1, PLCB1, FN1, NOX1, HRAS, ICAM1, IL1A, IL1B, IL6, CXCL8, JAK2, JUN, KRAS, SMAD2, SMAD3, SMAD4, MMP2, NFATC1, NFKB1, NOS3, NRAS, NOX4, SERPINE1, PLCE1, PIK3CA, PIK3CB, PIM1, PIK3CD, PIK3R1, PIK3R2, PLCB2, PLCB3, PLCB4, PLCD1, PLCG1, PLCG2, PRKCA, PRKCB, PRKCD, PRKCE, PRKCZ, MAPK1, MAPK3, MAPK8, MAPK11, MAPK9, MAPK10, MAPK13, BAX, RAC1, CCND1, BCL2, RELA, MAPK12, CCL2, SELE, STAT1, STAT3, STAT5A, STAT5B, TGFB1, TGFB2, TGFB3, TGFBR1, TGFBR2, THBD, TNF, VCAM1, VEGFA, VEGFB, VEGFC, CASP3, PLCD4, PIK3R3, CDC42

Alanine, aspartate and glutamate metabolism

ADSS1, CPS1, GOT1L1, ADSL, ADSS2, ABAT, AGXT, FOLH1, GAD1, GAD2, IL4I1, GFPT1, GLS2, GLS, GLUD1, GLUD2, GLUL, GOT1, GOT2, RIMKLA, GPT, NAT8L, ASL, ASNS, ASPA, ASS1, PPAT, NIT2, RIMKLB, AGXT2, CAD, ALDH5A1, ASRGL1, GPT2, DDO, ALDH4A1, GFPT2

Alcoholic liver disease

AKT3, C4B_2, TAB1, CAMKK2, PPARGC1A, -, TIRAP, CHUK, ADH1A, ADH1B, ADH1C, CPT1C, ADH4, ADH5, ADH6, ADH7, CPT1A, CPT1B, MAPK14, TICAM1, CTNNB1, CYP2E1, AKT1, AKT2, FABP1, ALDH2, ALDH1B1, FASN, ALDH9A1, ALDH3A2, FOXO1, FOXO3, TAB2, LPIN1, SIRT1, MLYCD, LY96, IL17RA, TAB3, TBK1, CXCL1, CXCL2, CXCL3, GSK3B, TRA2A, ACACA, ACACB, ACADM, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, FAS, IKBKB, IL1B, FASLG, IL6, CXCL8, IL12A, IL12B, IL17A, IRAK1, IRF3, ACADVL, LBP, MIR217, MAP3K5, MYD88, NFKB1, NFKBIA, ALDH7A1, NOX4, ACOX1, ADIPOR1, IRAK4, LEF1, PRKAG2, PRKAG3, PPARA, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, MAPK8, MAPK11, MAPK9, MAPK10, MAPK13, MAP2K3, MAP2K6, MAP2K7, CCND1, RELA, MAPK12, SCD, MAP2K4, TRA2B, LPIN3, SREBF1, MAP3K7, TCF7, TCF7L2, TLR4, C1QA, TNF, C1QB, TNFRSF1A, C1QC, C2, C3, TRAF3, TRAF6, C3AR1, C4A, C4B, C5, C5AR1, ADIPOR2, SCD5, ACOX3, TCF7L1, CASP3, CASP8, IL17RC, IKBKG, TRADD, RIPK1, FADD, MAP3K14, CD14, ADIPOQ, IKBKE, LPIN2