ZNG1E (Zn regulated GTPase metalloprotein activator 1E)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 220869
• Gene name: Zn regulated GTPase metalloprotein activator 1E
• Gene symbol: ZNG1E
• Synonyms (NCBI Gene): CBWD3, CBWD5, DC36
• Chromosome: 9
• Chromosome location: 9q21.11

miRNA Show/Hide all (184)

miRTarBase ID	miRNA	Experiments	Reference
MIRT499128	hsa-miR-7-1-3p	PAR-CLIP	21572407
MIRT499127	hsa-miR-7-2-3p	PAR-CLIP	21572407
MIRT499126	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT504072	hsa-miR-4272	PAR-CLIP	21572407
MIRT499125	hsa-miR-3065-5p	PAR-CLIP	21572407
MIRT499124	hsa-miR-1909-5p	PAR-CLIP	21572407
MIRT499123	hsa-miR-7159-5p	PAR-CLIP	21572407
MIRT499122	hsa-miR-505-3p	PAR-CLIP	21572407
MIRT499121	hsa-miR-421	PAR-CLIP	21572407
MIRT499120	hsa-miR-1238-5p	PAR-CLIP	21572407
MIRT499119	hsa-miR-4758-5p	PAR-CLIP	21572407
MIRT499118	hsa-miR-4658	PAR-CLIP	21572407
MIRT499117	hsa-miR-6790-5p	PAR-CLIP	21572407
MIRT499115	hsa-miR-5089-3p	PAR-CLIP	21572407
MIRT499116	hsa-miR-8081	PAR-CLIP	21572407
MIRT499128	hsa-miR-7-1-3p	PAR-CLIP	21572407
MIRT499127	hsa-miR-7-2-3p	PAR-CLIP	21572407
MIRT499126	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT504072	hsa-miR-4272	PAR-CLIP	21572407
MIRT499125	hsa-miR-3065-5p	PAR-CLIP	21572407
MIRT499124	hsa-miR-1909-5p	PAR-CLIP	21572407
MIRT499123	hsa-miR-7159-5p	PAR-CLIP	21572407
MIRT499122	hsa-miR-505-3p	PAR-CLIP	21572407
MIRT499121	hsa-miR-421	PAR-CLIP	21572407
MIRT499120	hsa-miR-1238-5p	PAR-CLIP	21572407
MIRT499119	hsa-miR-4758-5p	PAR-CLIP	21572407
MIRT499118	hsa-miR-4658	PAR-CLIP	21572407
MIRT499117	hsa-miR-6790-5p	PAR-CLIP	21572407
MIRT499115	hsa-miR-5089-3p	PAR-CLIP	21572407
MIRT499116	hsa-miR-8081	PAR-CLIP	21572407
MIRT499128	hsa-miR-7-1-3p	PAR-CLIP	23446348
MIRT499127	hsa-miR-7-2-3p	PAR-CLIP	23446348
MIRT499126	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT504072	hsa-miR-4272	PAR-CLIP	23446348
MIRT499125	hsa-miR-3065-5p	PAR-CLIP	23446348
MIRT499124	hsa-miR-1909-5p	PAR-CLIP	23446348
MIRT499123	hsa-miR-7159-5p	PAR-CLIP	23446348
MIRT499122	hsa-miR-505-3p	PAR-CLIP	23446348
MIRT499121	hsa-miR-421	PAR-CLIP	23446348
MIRT499120	hsa-miR-1238-5p	PAR-CLIP	23446348
MIRT499119	hsa-miR-4758-5p	PAR-CLIP	23446348
MIRT499118	hsa-miR-4658	PAR-CLIP	23446348
MIRT499117	hsa-miR-6790-5p	PAR-CLIP	23446348
MIRT499115	hsa-miR-5089-3p	PAR-CLIP	23446348
MIRT499116	hsa-miR-8081	PAR-CLIP	23446348
MIRT499128	hsa-miR-7-1-3p	PAR-CLIP	24398324
MIRT499127	hsa-miR-7-2-3p	PAR-CLIP	24398324
MIRT499126	hsa-miR-511-3p	PAR-CLIP	24398324
MIRT499125	hsa-miR-3065-5p	PAR-CLIP	24398324
MIRT499124	hsa-miR-1909-5p	PAR-CLIP	24398324
MIRT499123	hsa-miR-7159-5p	PAR-CLIP	24398324
MIRT499122	hsa-miR-505-3p	PAR-CLIP	24398324
MIRT499121	hsa-miR-421	PAR-CLIP	24398324
MIRT499120	hsa-miR-1238-5p	PAR-CLIP	24398324
MIRT499119	hsa-miR-4758-5p	PAR-CLIP	24398324
MIRT499118	hsa-miR-4658	PAR-CLIP	24398324
MIRT499117	hsa-miR-6790-5p	PAR-CLIP	24398324
MIRT499115	hsa-miR-5089-3p	PAR-CLIP	24398324
MIRT499116	hsa-miR-8081	PAR-CLIP	24398324
MIRT499128	hsa-miR-7-1-3p	PAR-CLIP	21572407
MIRT499127	hsa-miR-7-2-3p	PAR-CLIP	21572407
MIRT499126	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT504072	hsa-miR-4272	PAR-CLIP	21572407
MIRT499125	hsa-miR-3065-5p	PAR-CLIP	21572407
MIRT499124	hsa-miR-1909-5p	PAR-CLIP	21572407
MIRT499123	hsa-miR-7159-5p	PAR-CLIP	21572407
MIRT499122	hsa-miR-505-3p	PAR-CLIP	21572407
MIRT499121	hsa-miR-421	PAR-CLIP	21572407
MIRT499120	hsa-miR-1238-5p	PAR-CLIP	21572407
MIRT499119	hsa-miR-4758-5p	PAR-CLIP	21572407
MIRT499118	hsa-miR-4658	PAR-CLIP	21572407
MIRT499117	hsa-miR-6790-5p	PAR-CLIP	21572407
MIRT499115	hsa-miR-5089-3p	PAR-CLIP	21572407
MIRT499116	hsa-miR-8081	PAR-CLIP	21572407
MIRT499128	hsa-miR-7-1-3p	PAR-CLIP	21572407
MIRT499127	hsa-miR-7-2-3p	PAR-CLIP	21572407
MIRT499126	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT504072	hsa-miR-4272	PAR-CLIP	21572407
MIRT499125	hsa-miR-3065-5p	PAR-CLIP	21572407
MIRT499124	hsa-miR-1909-5p	PAR-CLIP	21572407
MIRT499123	hsa-miR-7159-5p	PAR-CLIP	21572407
MIRT499122	hsa-miR-505-3p	PAR-CLIP	21572407
MIRT499121	hsa-miR-421	PAR-CLIP	21572407
MIRT499120	hsa-miR-1238-5p	PAR-CLIP	21572407
MIRT499119	hsa-miR-4758-5p	PAR-CLIP	21572407
MIRT499118	hsa-miR-4658	PAR-CLIP	21572407
MIRT499117	hsa-miR-6790-5p	PAR-CLIP	21572407
MIRT499115	hsa-miR-5089-3p	PAR-CLIP	21572407
MIRT499116	hsa-miR-8081	PAR-CLIP	21572407
MIRT499128	hsa-miR-7-1-3p	PAR-CLIP	23446348
MIRT499127	hsa-miR-7-2-3p	PAR-CLIP	23446348
MIRT499126	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT504072	hsa-miR-4272	PAR-CLIP	23446348
MIRT499125	hsa-miR-3065-5p	PAR-CLIP	23446348
MIRT499124	hsa-miR-1909-5p	PAR-CLIP	23446348
MIRT499123	hsa-miR-7159-5p	PAR-CLIP	23446348
MIRT499122	hsa-miR-505-3p	PAR-CLIP	23446348
MIRT499121	hsa-miR-421	PAR-CLIP	23446348
MIRT499120	hsa-miR-1238-5p	PAR-CLIP	23446348
MIRT499119	hsa-miR-4758-5p	PAR-CLIP	23446348
MIRT499118	hsa-miR-4658	PAR-CLIP	23446348
MIRT499117	hsa-miR-6790-5p	PAR-CLIP	23446348
MIRT499115	hsa-miR-5089-3p	PAR-CLIP	23446348
MIRT499116	hsa-miR-8081	PAR-CLIP	23446348
MIRT499128	hsa-miR-7-1-3p	PAR-CLIP	24398324
MIRT499127	hsa-miR-7-2-3p	PAR-CLIP	24398324
MIRT499126	hsa-miR-511-3p	PAR-CLIP	24398324
MIRT499125	hsa-miR-3065-5p	PAR-CLIP	24398324
MIRT499124	hsa-miR-1909-5p	PAR-CLIP	24398324
MIRT499123	hsa-miR-7159-5p	PAR-CLIP	24398324
MIRT499122	hsa-miR-505-3p	PAR-CLIP	24398324
MIRT499121	hsa-miR-421	PAR-CLIP	24398324
MIRT499120	hsa-miR-1238-5p	PAR-CLIP	24398324
MIRT499119	hsa-miR-4758-5p	PAR-CLIP	24398324
MIRT499118	hsa-miR-4658	PAR-CLIP	24398324
MIRT499117	hsa-miR-6790-5p	PAR-CLIP	24398324
MIRT499115	hsa-miR-5089-3p	PAR-CLIP	24398324
MIRT499116	hsa-miR-8081	PAR-CLIP	24398324
MIRT2497532	hsa-miR-1207-3p	CLIP-seq
MIRT2497533	hsa-miR-2113	CLIP-seq
MIRT2497534	hsa-miR-2276	CLIP-seq
MIRT2497535	hsa-miR-297	CLIP-seq
MIRT2497536	hsa-miR-30a	CLIP-seq
MIRT2497537	hsa-miR-30b	CLIP-seq
MIRT2497538	hsa-miR-30c	CLIP-seq
MIRT2497539	hsa-miR-30d	CLIP-seq
MIRT2497540	hsa-miR-30e	CLIP-seq
MIRT2497541	hsa-miR-3117-5p	CLIP-seq
MIRT2497542	hsa-miR-3145-3p	CLIP-seq
MIRT2497543	hsa-miR-3145-5p	CLIP-seq
MIRT2497544	hsa-miR-3149	CLIP-seq
MIRT2497545	hsa-miR-3152-3p	CLIP-seq
MIRT2497546	hsa-miR-3168	CLIP-seq
MIRT2497547	hsa-miR-340	CLIP-seq
MIRT2497548	hsa-miR-3611	CLIP-seq
MIRT2497549	hsa-miR-3662	CLIP-seq
MIRT2497550	hsa-miR-3675-3p	CLIP-seq
MIRT2497551	hsa-miR-380	CLIP-seq
MIRT2497552	hsa-miR-382	CLIP-seq
MIRT2497553	hsa-miR-410	CLIP-seq
MIRT2497554	hsa-miR-4263	CLIP-seq
MIRT2497555	hsa-miR-4282	CLIP-seq
MIRT2497556	hsa-miR-4495	CLIP-seq
MIRT2497557	hsa-miR-4528	CLIP-seq
MIRT2497558	hsa-miR-4670-3p	CLIP-seq
MIRT2497559	hsa-miR-4772-3p	CLIP-seq
MIRT2497560	hsa-miR-4795-3p	CLIP-seq
MIRT2497561	hsa-miR-488	CLIP-seq
MIRT2497562	hsa-miR-581	CLIP-seq
MIRT2497563	hsa-miR-607	CLIP-seq
MIRT2497564	hsa-miR-653	CLIP-seq
MIRT2497565	hsa-miR-656	CLIP-seq
MIRT2497566	hsa-miR-758	CLIP-seq
MIRT2497532	hsa-miR-1207-3p	CLIP-seq
MIRT2497533	hsa-miR-2113	CLIP-seq
MIRT2497534	hsa-miR-2276	CLIP-seq
MIRT2497536	hsa-miR-30a	CLIP-seq
MIRT2497537	hsa-miR-30b	CLIP-seq
MIRT2497538	hsa-miR-30c	CLIP-seq
MIRT2497539	hsa-miR-30d	CLIP-seq
MIRT2497540	hsa-miR-30e	CLIP-seq
MIRT2497541	hsa-miR-3117-5p	CLIP-seq
MIRT2497542	hsa-miR-3145-3p	CLIP-seq
MIRT2497543	hsa-miR-3145-5p	CLIP-seq
MIRT2497545	hsa-miR-3152-3p	CLIP-seq
MIRT2497546	hsa-miR-3168	CLIP-seq
MIRT2497547	hsa-miR-340	CLIP-seq
MIRT2497548	hsa-miR-3611	CLIP-seq
MIRT2497549	hsa-miR-3662	CLIP-seq
MIRT2497550	hsa-miR-3675-3p	CLIP-seq
MIRT2497551	hsa-miR-380	CLIP-seq
MIRT2497552	hsa-miR-382	CLIP-seq
MIRT2497554	hsa-miR-4263	CLIP-seq
MIRT2497555	hsa-miR-4282	CLIP-seq
MIRT2497556	hsa-miR-4495	CLIP-seq
MIRT2497557	hsa-miR-4528	CLIP-seq
MIRT2497558	hsa-miR-4670-3p	CLIP-seq
MIRT2497559	hsa-miR-4772-3p	CLIP-seq
MIRT2497560	hsa-miR-4795-3p	CLIP-seq
MIRT2497561	hsa-miR-488	CLIP-seq
MIRT2497562	hsa-miR-581	CLIP-seq
MIRT2497563	hsa-miR-607	CLIP-seq
MIRT2497564	hsa-miR-653	CLIP-seq
MIRT2497566	hsa-miR-758	CLIP-seq

Gene ontology (GO) Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0003924	Function	GTPase activity	ISS
GO:0005525	Function	GTP binding	IEA
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005737	Component	Cytoplasm	IBA
GO:0016787	Function	Hydrolase activity	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0051604	Process	Protein maturation	IDA	17114291
GO:0051604	Process	Protein maturation	ISS
GO:0051604	Process	Protein maturation	ISS
GO:0140827	Function	Zinc chaperone activity	ISS

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q5RIA9
• Protein name: Zinc-regulated GTPase metalloprotein activator 1E (EC 3.6.5.-) (Cobalamin synthase W domain-containing protein 5) (COBW domain-containing protein 5)
• Protein function: Zinc chaperone that directly transfers zinc cofactor to target metalloproteins, thereby activating them. Catalyzes zinc insertion into the active site of methionine aminopeptidase METAP1, which function to cleave the initiator methionine from po
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02492	cobW	43 → 231	CobW/HypB/UreG, nucleotide-binding domain	Domain
  PF07683	CobW_C	274 → 377	Cobalamin synthesis protein cobW C-terminal domain	Domain

• Sequence:

  MLPAVGSVDEEEDPAEEDCPELVPIETTQSEEEEKSGLGAKIPVTIITGYLGAGKTTLLN
  YILTEQHSKRVAVILNESGEGSALEKSLAVSQGGELYEEWLELRNGCLCCSVKDNGLRAI
  ENLMQKKGKFDDILLETTGLADPGAVTSMFWVDAELGSDIYLDGIITIVDSKYGLKHLTE
  EKPDGLINEATRQVALADIILINKTDLVPEEDVKKLRTTIRSINGLGQILETQRSRVDLS
  NVLDLHAFDSLSGISLQKKLQHVPGTQPHLDQSIVTITFEVPGNAKEEHLNMFIQNLLWE
  KNVRNKDNHCMEVIRLKGLVSIKDKSQQVIVQGVHELYDLEETPVSWKDDTERTNRLVLI
  GRNLDKDILKQLFIATVTETEKQWTTHFKEDQVCT

• Sequence length: 395

Related Genes

No strongly related genes found yet for ZNG1E.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZNG1E.