Log in to save this analysis

Save This Analysis

Gene Gene information from NCBI Gene database.
Entrez ID 170960
Gene name Zinc finger protein 721
Gene symbol ZNF721
Synonyms (NCBI Gene)
-
Chromosome 4
Chromosome location 4p16.3
miRNA miRNA information provided by mirtarbase database.
333 Show/Hide all (333)
miRTarBase ID miRNA Experiments Reference
MIRT019234 hsa-miR-331-3p Sequencing 20371350
MIRT031175 hsa-miR-19b-3p Sequencing 20371350
MIRT726019 hsa-miR-19a-3p HITS-CLIP 22473208
MIRT031175 hsa-miR-19b-3p HITS-CLIP 22473208
MIRT726017 hsa-miR-92a-3p HITS-CLIP 22473208
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
7 Show/Hide all (7)
GO ID Ontology Definition Evidence Reference
GO:0003677 Function DNA binding IEA
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IEA
GO:0006357 Process Regulation of transcription by RNA polymerase II IBA
GO:0008270 Function Zinc ion binding IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8TF20
Protein name Zinc finger protein 721
Protein function May be involved in transcriptional regulation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00096 zf-C2H2 685 → 707 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 741 → 763 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 153 → 175 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 321 → 343 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 545 → 567 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 377 → 399 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 881 → 903 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 293 → 315 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 853 → 875 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 489 → 511 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 209 → 231 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 237 → 259 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 769 → 791 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 461 → 483 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 433 → 455 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 265 → 287 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 825 → 847 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 517 → 539 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 629 → 650 Zinc finger, C2H2 type Domain
PF13912 zf-C2H2_6 573 → 598 Domain
PF13912 zf-C2H2_6 349 → 374 Domain
PF13912 zf-C2H2_6 96 → 119 Domain
PF13912 zf-C2H2_6 656 → 682 Domain
PF16622 zf-C2H2_11 794 → 819 zinc-finger C2H2-type Domain
Sequence
MCSHFTQDFLPVQGIEDSFHKLILRRYEKCGHDNLQLRKGCKSMNVCKVQKGVYNGINKC
LSNTQSKIFQCNARVKVFSKFANSNKDKTRHTGEKHFKCNECGKSFQKFSDLTQHKGIHA
GEKPYTCEERGKDFGWYTDLNQHKKIHTGEKPYKCEECGKAFNRSTNLTAHKRIHNREKA
YTGEDRDRAFGWSTNLNEYKKIHTGDKPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKCK
ECGKVISSSSSFAKHKRIH
TGEKPFKCLECGKAFNISTTLTKHRRIHTGEKPYTCEVCGK
AFRQSANLYVHRRIH
TGEKPYTCGECGKTFRQSANLYVHRRIHTGEKPYKCEDCGKAFGR
YTALNQHKKIHTGE
KPYKCEECGKAFNSSTNLTAHKRIHTREKPYTCEDRGRAFGLSTNL
NEYKKIHTGDKPYKCKECGKAFIHSLHLNKHEKIHTGKKPYKCKQCGKVITSSSSFAKHK
RIH
TGEKPFECLECGKAFTSSTTLTKHRRIHTGEKPYTCEVCGKAFRQSAILYVHRRIHT
GEKPYTCEECGKTFRQSANLYVHRRIHTGEKPYKCEECGKAFGRYTDLNQHKKIHTGEKL
YKCEECGKDFVWYTDLNQQKKIYTGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCE
ECGKAFGWSIALNQHKKIHTGE
KPYKCEECGKAFSRSRNLTTHRRVHTREKPYKCEDRGR
SFGWSTNLNEYKKIHTGDKLYKCKECGKVFKQSSHLNRHEKIHTGKKPYKCKECGKVITS
SSSFAKHKRIH
TGEKPFKCLECGKAFTSSTTLTKHRRIHTGEKPYTCEECGKAFRQSAIL
YVHRRIH
TGEKPYTCGECGKTFRQSANLYAHKKIHTGEKPYTCGDCGKTFRQSANLYAHK
KIH
TGDKTIQV
Sequence length 911
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Generic Transcription Pathway
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Reference Evidence Score
EBV-positive nodal T- and NK-cell lymphoma Likely benign ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations