ZNF606 (zinc finger protein 606)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 80095
• Gene name: Zinc finger protein 606
• Gene symbol: ZNF606
• Synonyms (NCBI Gene): ZNF328
• Chromosome: 19
• Chromosome location: 19q13.43
• Summary: This gene encodes a zinc finger protein containing a Kruppel-associated box (KRAB) domain at its N-terminus, followed by contiguous C2H2 zinc finger motifs. The encoded protein is a nuclear protein that can act as a transcriptional repressor of growth fac

miRNA Show/Hide all (107)

miRTarBase ID	miRNA	Experiments	Reference
MIRT026992	hsa-miR-103a-3p	Sequencing	20371350
MIRT052134	hsa-let-7b-5p	CLASH	23622248
MIRT499541	hsa-miR-3662	PAR-CLIP	24398324
MIRT499540	hsa-miR-224-3p	PAR-CLIP	24398324
MIRT499539	hsa-miR-522-3p	PAR-CLIP	24398324
MIRT499538	hsa-miR-34b-3p	PAR-CLIP	24398324
MIRT499537	hsa-miR-3163	PAR-CLIP	24398324
MIRT499536	hsa-miR-1827	PAR-CLIP	24398324
MIRT026992	hsa-miR-103a-3p	PAR-CLIP	24398324
MIRT499535	hsa-miR-107	PAR-CLIP	24398324
MIRT499534	hsa-miR-185-5p	PAR-CLIP	24398324
MIRT499532	hsa-miR-4306	PAR-CLIP	24398324
MIRT499533	hsa-miR-4644	PAR-CLIP	24398324
MIRT499531	hsa-miR-5192	PAR-CLIP	24398324
MIRT499530	hsa-miR-653-3p	PAR-CLIP	24398324
MIRT499541	hsa-miR-3662	PAR-CLIP	24398324
MIRT499540	hsa-miR-224-3p	PAR-CLIP	24398324
MIRT499539	hsa-miR-522-3p	PAR-CLIP	24398324
MIRT499538	hsa-miR-34b-3p	PAR-CLIP	24398324
MIRT499537	hsa-miR-3163	PAR-CLIP	24398324
MIRT499536	hsa-miR-1827	PAR-CLIP	24398324
MIRT026992	hsa-miR-103a-3p	PAR-CLIP	24398324
MIRT499535	hsa-miR-107	PAR-CLIP	24398324
MIRT499534	hsa-miR-185-5p	PAR-CLIP	24398324
MIRT499532	hsa-miR-4306	PAR-CLIP	24398324
MIRT499533	hsa-miR-4644	PAR-CLIP	24398324
MIRT499531	hsa-miR-5192	PAR-CLIP	24398324
MIRT499530	hsa-miR-653-3p	PAR-CLIP	24398324
MIRT1531520	hsa-miR-141	CLIP-seq
MIRT1531521	hsa-miR-200a	CLIP-seq
MIRT1531522	hsa-miR-338-3p	CLIP-seq
MIRT1531523	hsa-miR-342-3p	CLIP-seq
MIRT1531524	hsa-miR-3614-5p	CLIP-seq
MIRT1531525	hsa-miR-3978	CLIP-seq
MIRT1531526	hsa-miR-4422	CLIP-seq
MIRT1531527	hsa-miR-4530	CLIP-seq
MIRT1531528	hsa-miR-4775	CLIP-seq
MIRT1531529	hsa-miR-4795-3p	CLIP-seq
MIRT1531530	hsa-miR-483-3p	CLIP-seq
MIRT1531531	hsa-miR-590-3p	CLIP-seq
MIRT1531532	hsa-miR-622	CLIP-seq
MIRT1531533	hsa-miR-664	CLIP-seq
MIRT1531534	hsa-miR-890	CLIP-seq
MIRT2160671	hsa-miR-198	CLIP-seq
MIRT2160672	hsa-miR-205	CLIP-seq
MIRT1531522	hsa-miR-338-3p	CLIP-seq
MIRT2160673	hsa-miR-378g	CLIP-seq
MIRT2160674	hsa-miR-4521	CLIP-seq
MIRT1531527	hsa-miR-4530	CLIP-seq
MIRT2160675	hsa-miR-4652-3p	CLIP-seq
MIRT1531530	hsa-miR-483-3p	CLIP-seq
MIRT2160676	hsa-miR-603	CLIP-seq
MIRT1531532	hsa-miR-622	CLIP-seq
MIRT2160677	hsa-miR-642b	CLIP-seq
MIRT2379895	hsa-miR-101	CLIP-seq
MIRT2379896	hsa-miR-132	CLIP-seq
MIRT2379897	hsa-miR-181a	CLIP-seq
MIRT2379898	hsa-miR-181b	CLIP-seq
MIRT2379899	hsa-miR-181c	CLIP-seq
MIRT2379900	hsa-miR-181d	CLIP-seq
MIRT2379901	hsa-miR-194	CLIP-seq
MIRT2160671	hsa-miR-198	CLIP-seq
MIRT2379902	hsa-miR-212	CLIP-seq
MIRT1531522	hsa-miR-338-3p	CLIP-seq
MIRT1531523	hsa-miR-342-3p	CLIP-seq
MIRT2160673	hsa-miR-378g	CLIP-seq
MIRT2379903	hsa-miR-3942-3p	CLIP-seq
MIRT2379904	hsa-miR-4262	CLIP-seq
MIRT2160674	hsa-miR-4521	CLIP-seq
MIRT1531527	hsa-miR-4530	CLIP-seq
MIRT2160675	hsa-miR-4652-3p	CLIP-seq
MIRT2379905	hsa-miR-4662a-5p	CLIP-seq
MIRT2379906	hsa-miR-548a-3p	CLIP-seq
MIRT2379907	hsa-miR-548e	CLIP-seq
MIRT2379908	hsa-miR-548f	CLIP-seq
MIRT2379909	hsa-miR-600	CLIP-seq
MIRT2160676	hsa-miR-603	CLIP-seq
MIRT1531532	hsa-miR-622	CLIP-seq
MIRT2160677	hsa-miR-642b	CLIP-seq
MIRT2672068	hsa-miR-1283	CLIP-seq
MIRT2160671	hsa-miR-198	CLIP-seq
MIRT1531522	hsa-miR-338-3p	CLIP-seq
MIRT2160673	hsa-miR-378g	CLIP-seq
MIRT2160674	hsa-miR-4521	CLIP-seq
MIRT1531527	hsa-miR-4530	CLIP-seq
MIRT2160675	hsa-miR-4652-3p	CLIP-seq
MIRT2672069	hsa-miR-4698	CLIP-seq
MIRT2672070	hsa-miR-491-3p	CLIP-seq
MIRT2672071	hsa-miR-501-3p	CLIP-seq
MIRT2672072	hsa-miR-502-3p	CLIP-seq
MIRT2160676	hsa-miR-603	CLIP-seq
MIRT1531532	hsa-miR-622	CLIP-seq
MIRT2160677	hsa-miR-642b	CLIP-seq
MIRT2672068	hsa-miR-1283	CLIP-seq
MIRT2160671	hsa-miR-198	CLIP-seq
MIRT1531522	hsa-miR-338-3p	CLIP-seq
MIRT2160673	hsa-miR-378g	CLIP-seq
MIRT2160674	hsa-miR-4521	CLIP-seq
MIRT1531527	hsa-miR-4530	CLIP-seq
MIRT2160675	hsa-miR-4652-3p	CLIP-seq
MIRT2672069	hsa-miR-4698	CLIP-seq
MIRT2672070	hsa-miR-491-3p	CLIP-seq
MIRT2672071	hsa-miR-501-3p	CLIP-seq
MIRT2672072	hsa-miR-502-3p	CLIP-seq
MIRT2160676	hsa-miR-603	CLIP-seq
MIRT1531532	hsa-miR-622	CLIP-seq
MIRT2160677	hsa-miR-642b	CLIP-seq

Gene ontology (GO) Show/Hide all (9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 613905
• HGNC: 25879
• e!Ensembl: ENSG00000166704

Protein

• UniProt ID: Q8WXB4
• Protein name: Zinc finger protein 606 (Zinc finger protein 328)
• Protein function: May act as a transcriptional repressor.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	428 → 450	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	708 → 730	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	568 → 590	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	512 → 534	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	652 → 674	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	484 → 506	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	624 → 646	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	540 → 562	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	736 → 758	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	456 → 478	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	764 → 786	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	596 → 618	Zinc finger, C2H2 type	Domain
  PF01352	KRAB	61 → 102	KRAB box	Family

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed in adult and fetal tissues. {ECO:0000269|PubMed:15964554}.
• Sequence:

  MAAINPWASWGALTDQSWGMTAVDPWASWALCPQYPAWHVEGSLEEGRRATGLPAAQVQE
  PVTFKDVAVDFTQEEWGQLDLVQRTLYRDVMLETYGHLLSVGNQIAKPEVISLLEQGEEP
  WSVEQACPQRTCPEWVRNLESKALIPAQSIFEEEQSHGMKLERYIWDDPWFSRLEVLGCK
  DQLEMYHMNQSTAMRQMVFMQKQVLSQRSSEFCGLGAEFSQNLNFVPSQRVSQIEHFYKP
  DTHAQSWRCDSAIMYADKVTCENNDYDKTVYQSIQPIYPARIQTGDNLFKCTDAVKSFNH
  IIHFGDHKGIHTGEKLYEYKECHQIFNQSPSFNEHPRLHVGENQYNYKEYENIFYFSSFM
  EHQKIGTVEKAYKYNEWEKVFGYDSFLTQHTSTYTAEKPYDYNECGTSFIWSSYLIQHKK
  THTGEKPYECDKCGKVFRNRSALTKHERTHTGIKPYECNKCGKAFSWNSHLIVHKRIHTG
  EKPYVCNECGKSFNWNSHLIGHQRTHTGEKPFECTECGKSFSWSSHLIAHMRMHTGEKPF
  KCDECEKAFRDYSALSKHERTHSGAKPYKCTECGKSFSWSSHLIAHQRTHTGEKPYNCQE
  CGKAFRERSALTKHEIIHSGIKPYECNKCGKSCSQMAHLVRHQRTHTGEKPYECNKCGKS
  FSQSCHLVAHRRIHTGEKPYKCNQCERSFNCSSHLIAHRRTHTGEKPYRCNECGKAFNES
  SSLIVHLRNHTGEKPYKCNHCEKAFCKNSSLIIHQRMHSGEKRFICSECGKAFSGHSALL
  QHQRNHSEEKLN

• Sequence length: 792

Pathways

Reactome Pathway:

Generic Transcription Pathway

Related Genes

No strongly related genes found yet for ZNF606.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZNF606.