ZNF496 (zinc finger protein 496)

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Gene miRNA Gene ontology Other IDs Protein Pathways Diseases linked via similar genes

Gene

• Entrez ID: 84838
• Gene name: Zinc finger protein 496
• Gene symbol: ZNF496
• Synonyms (NCBI Gene): NIZP1, ZFP496, ZKSCAN17, ZSCAN49
• Chromosome: 1
• Chromosome location: 1q44

miRNA Show/Hide all (41)

miRTarBase ID	miRNA	Experiments	Reference
MIRT044474	hsa-miR-320a	CLASH	23622248
MIRT442303	hsa-miR-329-3p	PAR-CLIP	22100165
MIRT442302	hsa-miR-362-3p	PAR-CLIP	22100165
MIRT442301	hsa-miR-6830-5p	PAR-CLIP	22100165
MIRT442300	hsa-miR-2115-5p	PAR-CLIP	22100165
MIRT442299	hsa-miR-3692-3p	PAR-CLIP	22100165
MIRT439198	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439198	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT442303	hsa-miR-329-3p	PAR-CLIP	22100165
MIRT442302	hsa-miR-362-3p	PAR-CLIP	22100165
MIRT442301	hsa-miR-6830-5p	PAR-CLIP	22100165
MIRT442300	hsa-miR-2115-5p	PAR-CLIP	22100165
MIRT442299	hsa-miR-3692-3p	PAR-CLIP	22100165
MIRT1526743	hsa-miR-1226	CLIP-seq
MIRT1526744	hsa-miR-29a	CLIP-seq
MIRT1526745	hsa-miR-29b	CLIP-seq
MIRT1526746	hsa-miR-29c	CLIP-seq
MIRT1526747	hsa-miR-3065-3p	CLIP-seq
MIRT1526748	hsa-miR-4316	CLIP-seq
MIRT1526749	hsa-miR-4632	CLIP-seq
MIRT1526750	hsa-miR-4710	CLIP-seq
MIRT1526743	hsa-miR-1226	CLIP-seq
MIRT1526744	hsa-miR-29a	CLIP-seq
MIRT1526745	hsa-miR-29b	CLIP-seq
MIRT1526746	hsa-miR-29c	CLIP-seq
MIRT1526747	hsa-miR-3065-3p	CLIP-seq
MIRT2159180	hsa-miR-3184	CLIP-seq
MIRT2159181	hsa-miR-3689d	CLIP-seq
MIRT2159182	hsa-miR-383	CLIP-seq
MIRT2159183	hsa-miR-423-5p	CLIP-seq
MIRT2159184	hsa-miR-4419a	CLIP-seq
MIRT2159185	hsa-miR-4459	CLIP-seq
MIRT2159186	hsa-miR-4510	CLIP-seq
MIRT1526750	hsa-miR-4710	CLIP-seq
MIRT2159187	hsa-miR-4761-5p	CLIP-seq
MIRT2159188	hsa-miR-4772-5p	CLIP-seq
MIRT2159189	hsa-miR-4779	CLIP-seq
MIRT2159190	hsa-miR-486-3p	CLIP-seq
MIRT2159184	hsa-miR-4419a	CLIP-seq
MIRT2159186	hsa-miR-4510	CLIP-seq
MIRT2378582	hsa-miR-574-3p	CLIP-seq

Gene ontology (GO) Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0003677	Function	DNA binding	ISS
GO:0005515	Function	Protein binding	IPI	16189514, 25416956, 25910212, 26871637, 31403225, 31515488, 32296183, 32814053
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	ISS
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 613911
• HGNC: 23713
• e!Ensembl: ENSG00000162714

Protein

• UniProt ID: Q96IT1
• Protein name: Zinc finger protein 496 (Zinc finger protein with KRAB and SCAN domains 17)
• Protein function: DNA-binding transcription factor that can both act as an activator and a repressor.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	553 → 575	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	463 → 485	Zinc finger, C2H2 type	Domain
  PF01352	KRAB	222 → 256	KRAB box	Family
  PF02023	SCAN	38 → 127	SCAN domain	Domain

• Sequence:

  MPTALCPRVLAPKESEEPRKMRSPPGENPSPQGELPSPESSRRLFRRFRYQEAAGPREAL
  QRLWDLCGGWLRPERHTKEQILELLVLEQFLAILPREIQSWVRAQEPESGEQAVAAVEAL
  EREPGRPWQWLKHCEDPVVIDDGDSPLDQEQEQLPVEPHSDLAKNQDAQPITLAQCLGLP
  SRPPSQLSGDPVLQDAFLLQEENVRDTQQVTTLQLPPSRVSPFKDMILCFSEEDWSLLDP
  AQTGFYGEFIIGEDYGVSMPPNDLAAQPDLSQGEENEPRVPELQDLQGKEVPQVSYLDSP
  SLQPFQVEERRKREELQVPEFQACPQTVVPQNTYPAGGNPRSLENSLDEEVTIEIVLSSS
  GDEDSQHGPYCTEELGSPTEKQRSLPASHRSSTEAGGEVQTSKKSYVCPNCGKIFRWRVN
  FIRHLRSRREQEKPHECSVCGELFSDSEDLDGHLESHEAQKPYRCGACGKSFRLNSHLLS
  HRRIHLQPDRLQPVEKREQAASEDADKGPKEPLENGKAKLSFQCCECGKAFQRHDHLARH
  RSHFHLKDKARPFQCRYCVKSFTQNYDLLRHERLHMKRRSKQALNSY

• Sequence length: 587

Pathways

Reactome Pathway:

Generic Transcription Pathway

Related Genes

No strongly related genes found yet for ZNF496.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZNF496.