ZNF461 (zinc finger protein 461)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 92283
• Gene name: Zinc finger protein 461
• Gene symbol: ZNF461
• Synonyms (NCBI Gene): GIOT-1, GIOT1, HZF28
• Chromosome: 19
• Chromosome location: 19q13.12

miRNA Show/Hide all (161)

miRTarBase ID	miRNA	Experiments	Reference
MIRT017024	hsa-miR-335-5p	Microarray	18185580
MIRT1525628	hsa-miR-1193	CLIP-seq
MIRT1525629	hsa-miR-197	CLIP-seq
MIRT1525630	hsa-miR-1976	CLIP-seq
MIRT1525631	hsa-miR-2054	CLIP-seq
MIRT1525632	hsa-miR-2392	CLIP-seq
MIRT1525633	hsa-miR-3662	CLIP-seq
MIRT1525634	hsa-miR-4282	CLIP-seq
MIRT1525635	hsa-miR-4310	CLIP-seq
MIRT1525636	hsa-miR-4454	CLIP-seq
MIRT1525637	hsa-miR-4643	CLIP-seq
MIRT1525638	hsa-miR-466	CLIP-seq
MIRT1525639	hsa-miR-4662a-5p	CLIP-seq
MIRT1525640	hsa-miR-4676-5p	CLIP-seq
MIRT1525641	hsa-miR-4707-3p	CLIP-seq
MIRT1525642	hsa-miR-4716-5p	CLIP-seq
MIRT1525643	hsa-miR-4786-5p	CLIP-seq
MIRT1525644	hsa-miR-4789-3p	CLIP-seq
MIRT1525645	hsa-miR-5096	CLIP-seq
MIRT1525646	hsa-miR-575	CLIP-seq
MIRT1525647	hsa-miR-656	CLIP-seq
MIRT1525648	hsa-miR-769-5p	CLIP-seq
MIRT1525628	hsa-miR-1193	CLIP-seq
MIRT1525629	hsa-miR-197	CLIP-seq
MIRT1525630	hsa-miR-1976	CLIP-seq
MIRT1525632	hsa-miR-2392	CLIP-seq
MIRT1525636	hsa-miR-4454	CLIP-seq
MIRT1525639	hsa-miR-4662a-5p	CLIP-seq
MIRT1525640	hsa-miR-4676-5p	CLIP-seq
MIRT1525641	hsa-miR-4707-3p	CLIP-seq
MIRT1525642	hsa-miR-4716-5p	CLIP-seq
MIRT1525645	hsa-miR-5096	CLIP-seq
MIRT1525646	hsa-miR-575	CLIP-seq
MIRT1525628	hsa-miR-1193	CLIP-seq
MIRT1525629	hsa-miR-197	CLIP-seq
MIRT1525630	hsa-miR-1976	CLIP-seq
MIRT1525632	hsa-miR-2392	CLIP-seq
MIRT1525636	hsa-miR-4454	CLIP-seq
MIRT1525639	hsa-miR-4662a-5p	CLIP-seq
MIRT1525640	hsa-miR-4676-5p	CLIP-seq
MIRT1525641	hsa-miR-4707-3p	CLIP-seq
MIRT1525642	hsa-miR-4716-5p	CLIP-seq
MIRT1525645	hsa-miR-5096	CLIP-seq
MIRT1525646	hsa-miR-575	CLIP-seq
MIRT2158838	hsa-miR-106a	CLIP-seq
MIRT2158839	hsa-miR-106b	CLIP-seq
MIRT1525628	hsa-miR-1193	CLIP-seq
MIRT2158840	hsa-miR-1234	CLIP-seq
MIRT2158841	hsa-miR-150	CLIP-seq
MIRT2158842	hsa-miR-17	CLIP-seq
MIRT2158843	hsa-miR-1827	CLIP-seq
MIRT1525630	hsa-miR-1976	CLIP-seq
MIRT2158844	hsa-miR-20a	CLIP-seq
MIRT2158845	hsa-miR-20b	CLIP-seq
MIRT2158846	hsa-miR-2114	CLIP-seq
MIRT2158847	hsa-miR-302a	CLIP-seq
MIRT2158848	hsa-miR-302b	CLIP-seq
MIRT2158849	hsa-miR-302c	CLIP-seq
MIRT2158850	hsa-miR-302d	CLIP-seq
MIRT2158851	hsa-miR-302e	CLIP-seq
MIRT2158852	hsa-miR-3664-3p	CLIP-seq
MIRT2158853	hsa-miR-372	CLIP-seq
MIRT2158854	hsa-miR-373	CLIP-seq
MIRT2158855	hsa-miR-3929	CLIP-seq
MIRT2158856	hsa-miR-4276	CLIP-seq
MIRT1525635	hsa-miR-4310	CLIP-seq
MIRT2158857	hsa-miR-4419b	CLIP-seq
MIRT2158858	hsa-miR-4420	CLIP-seq
MIRT2158859	hsa-miR-4433	CLIP-seq
MIRT1525636	hsa-miR-4454	CLIP-seq
MIRT2158860	hsa-miR-4459	CLIP-seq
MIRT2158861	hsa-miR-4478	CLIP-seq
MIRT2158862	hsa-miR-4649-3p	CLIP-seq
MIRT2158863	hsa-miR-4695-5p	CLIP-seq
MIRT1525641	hsa-miR-4707-3p	CLIP-seq
MIRT2158864	hsa-miR-4768-3p	CLIP-seq
MIRT2158865	hsa-miR-485-5p	CLIP-seq
MIRT2158866	hsa-miR-510	CLIP-seq
MIRT2158867	hsa-miR-512-3p	CLIP-seq
MIRT2158868	hsa-miR-512-5p	CLIP-seq
MIRT2158869	hsa-miR-519d	CLIP-seq
MIRT2158870	hsa-miR-520a-3p	CLIP-seq
MIRT2158871	hsa-miR-520b	CLIP-seq
MIRT2158872	hsa-miR-520c-3p	CLIP-seq
MIRT2158873	hsa-miR-520d-3p	CLIP-seq
MIRT2158874	hsa-miR-520e	CLIP-seq
MIRT2158875	hsa-miR-520g	CLIP-seq
MIRT2158876	hsa-miR-520h	CLIP-seq
MIRT2158877	hsa-miR-93	CLIP-seq
MIRT2158878	hsa-miR-940	CLIP-seq
MIRT1525628	hsa-miR-1193	CLIP-seq
MIRT1525629	hsa-miR-197	CLIP-seq
MIRT1525632	hsa-miR-2392	CLIP-seq
MIRT2378252	hsa-miR-411	CLIP-seq
MIRT1525639	hsa-miR-4662a-5p	CLIP-seq
MIRT1525640	hsa-miR-4676-5p	CLIP-seq
MIRT1525642	hsa-miR-4716-5p	CLIP-seq
MIRT2378253	hsa-miR-483-5p	CLIP-seq
MIRT1525645	hsa-miR-5096	CLIP-seq
MIRT1525646	hsa-miR-575	CLIP-seq
MIRT2158843	hsa-miR-1827	CLIP-seq
MIRT2158846	hsa-miR-2114	CLIP-seq
MIRT2158852	hsa-miR-3664-3p	CLIP-seq
MIRT2158855	hsa-miR-3929	CLIP-seq
MIRT2158857	hsa-miR-4419b	CLIP-seq
MIRT2158859	hsa-miR-4433	CLIP-seq
MIRT2158860	hsa-miR-4459	CLIP-seq
MIRT2158861	hsa-miR-4478	CLIP-seq
MIRT2158862	hsa-miR-4649-3p	CLIP-seq
MIRT2158863	hsa-miR-4695-5p	CLIP-seq
MIRT2158864	hsa-miR-4768-3p	CLIP-seq
MIRT2158865	hsa-miR-485-5p	CLIP-seq
MIRT2158866	hsa-miR-510	CLIP-seq
MIRT2158868	hsa-miR-512-5p	CLIP-seq
MIRT2158878	hsa-miR-940	CLIP-seq
MIRT2158843	hsa-miR-1827	CLIP-seq
MIRT2158846	hsa-miR-2114	CLIP-seq
MIRT2670565	hsa-miR-3148	CLIP-seq
MIRT2670566	hsa-miR-3661	CLIP-seq
MIRT2158852	hsa-miR-3664-3p	CLIP-seq
MIRT2670567	hsa-miR-3926	CLIP-seq
MIRT2158855	hsa-miR-3929	CLIP-seq
MIRT2670568	hsa-miR-433	CLIP-seq
MIRT2158857	hsa-miR-4419b	CLIP-seq
MIRT2158859	hsa-miR-4433	CLIP-seq
MIRT2158860	hsa-miR-4459	CLIP-seq
MIRT2158861	hsa-miR-4478	CLIP-seq
MIRT2158862	hsa-miR-4649-3p	CLIP-seq
MIRT2158863	hsa-miR-4695-5p	CLIP-seq
MIRT2670569	hsa-miR-4722-5p	CLIP-seq
MIRT2158864	hsa-miR-4768-3p	CLIP-seq
MIRT2670570	hsa-miR-4795-3p	CLIP-seq
MIRT2158865	hsa-miR-485-5p	CLIP-seq
MIRT2158866	hsa-miR-510	CLIP-seq
MIRT2158868	hsa-miR-512-5p	CLIP-seq
MIRT2670571	hsa-miR-548l	CLIP-seq
MIRT2670572	hsa-miR-548n	CLIP-seq
MIRT2670573	hsa-miR-548s	CLIP-seq
MIRT2670574	hsa-miR-619	CLIP-seq
MIRT2670575	hsa-miR-631	CLIP-seq
MIRT2670576	hsa-miR-664	CLIP-seq
MIRT2670577	hsa-miR-875-3p	CLIP-seq
MIRT2158878	hsa-miR-940	CLIP-seq
MIRT2158843	hsa-miR-1827	CLIP-seq
MIRT2158846	hsa-miR-2114	CLIP-seq
MIRT2158852	hsa-miR-3664-3p	CLIP-seq
MIRT2670567	hsa-miR-3926	CLIP-seq
MIRT2158855	hsa-miR-3929	CLIP-seq
MIRT2158857	hsa-miR-4419b	CLIP-seq
MIRT2158859	hsa-miR-4433	CLIP-seq
MIRT2158860	hsa-miR-4459	CLIP-seq
MIRT2158861	hsa-miR-4478	CLIP-seq
MIRT2158862	hsa-miR-4649-3p	CLIP-seq
MIRT2158863	hsa-miR-4695-5p	CLIP-seq
MIRT2670569	hsa-miR-4722-5p	CLIP-seq
MIRT2158864	hsa-miR-4768-3p	CLIP-seq
MIRT2158865	hsa-miR-485-5p	CLIP-seq
MIRT2158866	hsa-miR-510	CLIP-seq
MIRT2158868	hsa-miR-512-5p	CLIP-seq
MIRT2670573	hsa-miR-548s	CLIP-seq
MIRT2158878	hsa-miR-940	CLIP-seq

Gene ontology (GO) Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 608640
• HGNC: 21629
• e!Ensembl: ENSG00000197808

Protein

• UniProt ID: Q8TAF7
• Protein name: Zinc finger protein 461 (Gonadotropin-inducible ovary transcription repressor 1) (GIOT-1)
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	301 → 323	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	441 → 463	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	357 → 379	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	273 → 295	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	329 → 351	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	497 → 519	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	413 → 435	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	469 → 491	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	385 → 407	Zinc finger, C2H2 type	Domain
  PF01352	KRAB	5 → 46	KRAB box	Family

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed, with highest levels in liver, kidney, pancreas, thymus, and small intestine. {ECO:0000269|PubMed:15004467}.
• Sequence:

  MAHELVMFRDVAIDVSQEEWECLNPAQRNLYKEVMLENYSNLVSLGLSVSKPAVISSLEQ
  GKEPWMVVREETGRWCPGTWKTWGFHNNFLDNNEATDINADLASRDEPQKLSPKRDIYET
  ELSQWVNMEEFKSHSPERSIFSAIWEGNCHFEQHQGQEEGYFRQLMINHENMPIFSQHTL
  LTQEFYDREKISECKKCRKIFSYHLFFSHHKRTHSKELSECKECTEIVNTPCLFKQQTIQ
  NGDKCNECKECWKAFVHCSQLKHLRIHNGEKRYECNECGKAFNYGSELTLHQRIHTGEKP
  YECKECGKAFRQRSQLTQHQRLHTGEKPYECKQCGKAFIRGFQLTEHLRLHTGEKPYECK
  ECGKTFRHRSHLTIHQRIHTGEKPYECRECGKAFSYHSSFSHHQKIHSGKKPYECHECGK
  AFCDGLQLTLHQRIHTGEKPYECKECGKTFRQCSHLKRHQRIHTGEKPHECMICGKAFRL
  HSHLIQHQRIHTGEKPYECKECGKAFSYHSSFSHHQRIHSGKKPYQCGKAFNHRLQLNLH
  QTLHTGEKPVRFPLLPPHPSLAS

• Sequence length: 563

Pathways

Reactome Pathway:

Generic Transcription Pathway

Related Genes

No strongly related genes found yet for ZNF461.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZNF461.