ZNF451 (zinc finger protein 451)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 26036 |
| Gene name | Zinc finger protein 451 |
| Gene symbol | ZNF451 |
| Synonyms (NCBI Gene) |
COASTERZATTdJ417I1.1
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| Chromosome | 6 |
| Chromosome location | 6p12.1 |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9Y4E5 | ||||||||||
| Protein name | E3 SUMO-protein ligase ZNF451 (EC 2.3.2.-) (Coactivator for steroid receptors) (E3 SUMO-protein transferase ZNF451) (Zinc finger protein 451) | ||||||||||
| Protein function | E3 SUMO-protein ligase; has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins (PubMed:26524493, PubMed:26524494). Plays a role in protein SUMO2 modification in response to stress caused by DNA da | ||||||||||
| PDB | 5D2M | ||||||||||
| Family and domains |
Pfam
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| Sequence |
MGDPGSEIIESVPPAGPEASESTTDENEDDIQFVSEGPLRPVLEYIDLVSSDDEEPSTSY |
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| Sequence length | 1061 | ||||||||||
| Interactions | View interactions | ||||||||||
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Related Genes
Genes most often co-reported with ZNF451 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to ZNF451 (see Related Genes above), that are NOT already directly curated for ZNF451 itself -- a lead worth checking, not a confirmed association.
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