ZNF449 (zinc finger protein 449)

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Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 203523
• Gene name: Zinc finger protein 449
• Gene symbol: ZNF449
• Synonyms (NCBI Gene): ZSCAN19
• Chromosome: X
• Chromosome location: Xq26.3
• Summary: This gene encodes a nuclear protein that likely functions as a transcription factor. The protein includes an N-terminal SCAN domain, and seven C2H2-type zinc finger motifs. [provided by RefSeq, May 2010]

miRNA Show/Hide all (336)

miRTarBase ID	miRNA	Experiments	Reference
MIRT024699	hsa-miR-215-5p	Microarray	19074876
MIRT026158	hsa-miR-192-5p	Microarray	19074876
MIRT720072	hsa-miR-181d-5p	HITS-CLIP	19536157
MIRT720070	hsa-miR-181a-5p	HITS-CLIP	19536157
MIRT720069	hsa-miR-181b-5p	HITS-CLIP	19536157
MIRT720068	hsa-miR-181c-5p	HITS-CLIP	19536157
MIRT720066	hsa-miR-4262	HITS-CLIP	19536157
MIRT720067	hsa-miR-3675-3p	HITS-CLIP	19536157
MIRT720065	hsa-miR-4778-5p	HITS-CLIP	19536157
MIRT720063	hsa-miR-452-3p	HITS-CLIP	19536157
MIRT720062	hsa-miR-4684-5p	HITS-CLIP	19536157
MIRT720061	hsa-miR-3686	HITS-CLIP	19536157
MIRT720060	hsa-miR-335-3p	HITS-CLIP	19536157
MIRT720072	hsa-miR-181d-5p	HITS-CLIP	19536157
MIRT720070	hsa-miR-181a-5p	HITS-CLIP	19536157
MIRT720069	hsa-miR-181b-5p	HITS-CLIP	19536157
MIRT720068	hsa-miR-181c-5p	HITS-CLIP	19536157
MIRT720066	hsa-miR-4262	HITS-CLIP	19536157
MIRT720067	hsa-miR-3675-3p	HITS-CLIP	19536157
MIRT720065	hsa-miR-4778-5p	HITS-CLIP	19536157
MIRT720064	hsa-miR-4742-3p	HITS-CLIP	19536157
MIRT720063	hsa-miR-452-3p	HITS-CLIP	19536157
MIRT720062	hsa-miR-4684-5p	HITS-CLIP	19536157
MIRT720061	hsa-miR-3686	HITS-CLIP	19536157
MIRT720060	hsa-miR-335-3p	HITS-CLIP	19536157
MIRT564663	hsa-miR-4640-3p	PAR-CLIP	20371350
MIRT564662	hsa-miR-4759	PAR-CLIP	20371350
MIRT409554	hsa-miR-5582-5p	PAR-CLIP	20371350
MIRT564661	hsa-miR-3622a-5p	PAR-CLIP	20371350
MIRT409551	hsa-miR-411-5p	PAR-CLIP	20371350
MIRT564660	hsa-miR-6503-3p	PAR-CLIP	20371350
MIRT409552	hsa-miR-3935	PAR-CLIP	20371350
MIRT564659	hsa-miR-6798-3p	PAR-CLIP	20371350
MIRT409553	hsa-miR-4423-3p	PAR-CLIP	20371350
MIRT409551	hsa-miR-411-5p	PAR-CLIP	20371350
MIRT229345	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT229346	hsa-miR-107	PAR-CLIP	21572407
MIRT229347	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT229350	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT229343	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT229344	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT229349	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT229352	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT229357	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT552446	hsa-miR-503-5p	PAR-CLIP	21572407
MIRT552445	hsa-miR-619-3p	PAR-CLIP	21572407
MIRT552444	hsa-miR-646	PAR-CLIP	21572407
MIRT552443	hsa-miR-4781-3p	PAR-CLIP	21572407
MIRT552442	hsa-miR-499b-5p	PAR-CLIP	21572407
MIRT552441	hsa-miR-3661	PAR-CLIP	21572407
MIRT552440	hsa-miR-631	PAR-CLIP	21572407
MIRT229353	hsa-miR-4524a-5p	PAR-CLIP	21572407
MIRT229356	hsa-miR-4524b-5p	PAR-CLIP	21572407
MIRT229355	hsa-miR-5007-3p	PAR-CLIP	21572407
MIRT026158	hsa-miR-192-5p	PAR-CLIP	21572407
MIRT024699	hsa-miR-215-5p	PAR-CLIP	21572407
MIRT457718	hsa-miR-562	PAR-CLIP	23592263
MIRT457717	hsa-miR-944	PAR-CLIP	23592263
MIRT457716	hsa-miR-4274	PAR-CLIP	23592263
MIRT457715	hsa-miR-4519	PAR-CLIP	23592263
MIRT457714	hsa-miR-4495	PAR-CLIP	23592263
MIRT457713	hsa-miR-379-3p	PAR-CLIP	23592263
MIRT457712	hsa-miR-411-3p	PAR-CLIP	23592263
MIRT457711	hsa-miR-380-3p	PAR-CLIP	23592263
MIRT457710	hsa-miR-4302	PAR-CLIP	23592263
MIRT457709	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT457708	hsa-miR-567	PAR-CLIP	23592263
MIRT457707	hsa-miR-223-5p	PAR-CLIP	23592263
MIRT457706	hsa-miR-297	PAR-CLIP	23592263
MIRT457705	hsa-miR-2278	PAR-CLIP	23592263
MIRT720072	hsa-miR-181d-5p	HITS-CLIP	19536157
MIRT720070	hsa-miR-181a-5p	HITS-CLIP	19536157
MIRT720069	hsa-miR-181b-5p	HITS-CLIP	19536157
MIRT720068	hsa-miR-181c-5p	HITS-CLIP	19536157
MIRT720066	hsa-miR-4262	HITS-CLIP	19536157
MIRT720067	hsa-miR-3675-3p	HITS-CLIP	19536157
MIRT720065	hsa-miR-4778-5p	HITS-CLIP	19536157
MIRT720063	hsa-miR-452-3p	HITS-CLIP	19536157
MIRT720062	hsa-miR-4684-5p	HITS-CLIP	19536157
MIRT720061	hsa-miR-3686	HITS-CLIP	19536157
MIRT720060	hsa-miR-335-3p	HITS-CLIP	19536157
MIRT720072	hsa-miR-181d-5p	HITS-CLIP	19536157
MIRT720070	hsa-miR-181a-5p	HITS-CLIP	19536157
MIRT720069	hsa-miR-181b-5p	HITS-CLIP	19536157
MIRT720068	hsa-miR-181c-5p	HITS-CLIP	19536157
MIRT720066	hsa-miR-4262	HITS-CLIP	19536157
MIRT720067	hsa-miR-3675-3p	HITS-CLIP	19536157
MIRT720065	hsa-miR-4778-5p	HITS-CLIP	19536157
MIRT720064	hsa-miR-4742-3p	HITS-CLIP	19536157
MIRT720063	hsa-miR-452-3p	HITS-CLIP	19536157
MIRT720062	hsa-miR-4684-5p	HITS-CLIP	19536157
MIRT720061	hsa-miR-3686	HITS-CLIP	19536157
MIRT720060	hsa-miR-335-3p	HITS-CLIP	19536157
MIRT564663	hsa-miR-4640-3p	PAR-CLIP	20371350
MIRT564662	hsa-miR-4759	PAR-CLIP	20371350
MIRT409554	hsa-miR-5582-5p	PAR-CLIP	20371350
MIRT564661	hsa-miR-3622a-5p	PAR-CLIP	20371350
MIRT409551	hsa-miR-411-5p	PAR-CLIP	20371350
MIRT564660	hsa-miR-6503-3p	PAR-CLIP	20371350
MIRT409552	hsa-miR-3935	PAR-CLIP	20371350
MIRT564659	hsa-miR-6798-3p	PAR-CLIP	20371350
MIRT409553	hsa-miR-4423-3p	PAR-CLIP	20371350
MIRT409551	hsa-miR-411-5p	PAR-CLIP	20371350
MIRT229345	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT229346	hsa-miR-107	PAR-CLIP	21572407
MIRT229347	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT229350	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT229343	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT229344	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT229349	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT229352	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT229357	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT552446	hsa-miR-503-5p	PAR-CLIP	21572407
MIRT552445	hsa-miR-619-3p	PAR-CLIP	21572407
MIRT552444	hsa-miR-646	PAR-CLIP	21572407
MIRT552443	hsa-miR-4781-3p	PAR-CLIP	21572407
MIRT552442	hsa-miR-499b-5p	PAR-CLIP	21572407
MIRT552441	hsa-miR-3661	PAR-CLIP	21572407
MIRT552440	hsa-miR-631	PAR-CLIP	21572407
MIRT229353	hsa-miR-4524a-5p	PAR-CLIP	21572407
MIRT229356	hsa-miR-4524b-5p	PAR-CLIP	21572407
MIRT229355	hsa-miR-5007-3p	PAR-CLIP	21572407
MIRT026158	hsa-miR-192-5p	PAR-CLIP	21572407
MIRT024699	hsa-miR-215-5p	PAR-CLIP	21572407
MIRT457718	hsa-miR-562	PAR-CLIP	23592263
MIRT457717	hsa-miR-944	PAR-CLIP	23592263
MIRT457716	hsa-miR-4274	PAR-CLIP	23592263
MIRT457715	hsa-miR-4519	PAR-CLIP	23592263
MIRT457714	hsa-miR-4495	PAR-CLIP	23592263
MIRT457713	hsa-miR-379-3p	PAR-CLIP	23592263
MIRT457712	hsa-miR-411-3p	PAR-CLIP	23592263
MIRT457711	hsa-miR-380-3p	PAR-CLIP	23592263
MIRT457710	hsa-miR-4302	PAR-CLIP	23592263
MIRT457709	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT457708	hsa-miR-567	PAR-CLIP	23592263
MIRT457707	hsa-miR-223-5p	PAR-CLIP	23592263
MIRT457706	hsa-miR-297	PAR-CLIP	23592263
MIRT457705	hsa-miR-2278	PAR-CLIP	23592263
MIRT1525385	hsa-miR-103a	CLIP-seq
MIRT1525386	hsa-miR-1225-3p	CLIP-seq
MIRT1525387	hsa-miR-1233	CLIP-seq
MIRT1525388	hsa-miR-124	CLIP-seq
MIRT1525389	hsa-miR-153	CLIP-seq
MIRT1525390	hsa-miR-15a	CLIP-seq
MIRT1525391	hsa-miR-15b	CLIP-seq
MIRT1525392	hsa-miR-16	CLIP-seq
MIRT1525393	hsa-miR-186	CLIP-seq
MIRT1525394	hsa-miR-195	CLIP-seq
MIRT1525395	hsa-miR-2054	CLIP-seq
MIRT1525396	hsa-miR-25	CLIP-seq
MIRT1525397	hsa-miR-2682	CLIP-seq
MIRT1525398	hsa-miR-298	CLIP-seq
MIRT1525399	hsa-miR-3133	CLIP-seq
MIRT1525400	hsa-miR-32	CLIP-seq
MIRT1525401	hsa-miR-34a	CLIP-seq
MIRT1525402	hsa-miR-34c-5p	CLIP-seq
MIRT1525403	hsa-miR-3617	CLIP-seq
MIRT1525404	hsa-miR-363	CLIP-seq
MIRT1525405	hsa-miR-367	CLIP-seq
MIRT1525406	hsa-miR-3671	CLIP-seq
MIRT1525407	hsa-miR-3678-3p	CLIP-seq
MIRT1525408	hsa-miR-3714	CLIP-seq
MIRT1525409	hsa-miR-3910	CLIP-seq
MIRT1525410	hsa-miR-424	CLIP-seq
MIRT1525411	hsa-miR-4272	CLIP-seq
MIRT1525412	hsa-miR-4282	CLIP-seq
MIRT1525413	hsa-miR-4289	CLIP-seq
MIRT1525414	hsa-miR-4312	CLIP-seq
MIRT1525415	hsa-miR-4323	CLIP-seq
MIRT1525416	hsa-miR-4423-5p	CLIP-seq
MIRT1525417	hsa-miR-4433	CLIP-seq
MIRT1525418	hsa-miR-4477b	CLIP-seq
MIRT1525419	hsa-miR-448	CLIP-seq
MIRT1525420	hsa-miR-449a	CLIP-seq
MIRT1525421	hsa-miR-449b	CLIP-seq
MIRT1525422	hsa-miR-449c	CLIP-seq
MIRT1525423	hsa-miR-4506	CLIP-seq
MIRT1525424	hsa-miR-4524	CLIP-seq
MIRT1525425	hsa-miR-4680-3p	CLIP-seq
MIRT1525426	hsa-miR-4728-3p	CLIP-seq
MIRT1525427	hsa-miR-497	CLIP-seq
MIRT1525428	hsa-miR-499a-5p	CLIP-seq
MIRT1525429	hsa-miR-503	CLIP-seq
MIRT1525430	hsa-miR-506	CLIP-seq
MIRT1525431	hsa-miR-513a-5p	CLIP-seq
MIRT1525432	hsa-miR-548u	CLIP-seq
MIRT1525433	hsa-miR-555	CLIP-seq
MIRT1525434	hsa-miR-577	CLIP-seq
MIRT1525435	hsa-miR-582-5p	CLIP-seq
MIRT1525436	hsa-miR-607	CLIP-seq
MIRT1525437	hsa-miR-641	CLIP-seq
MIRT1525438	hsa-miR-645	CLIP-seq
MIRT1525439	hsa-miR-92a	CLIP-seq
MIRT1525440	hsa-miR-92b	CLIP-seq
MIRT2158764	hsa-miR-146a	CLIP-seq
MIRT2158765	hsa-miR-146b-5p	CLIP-seq
MIRT2158766	hsa-miR-219-5p	CLIP-seq
MIRT2158767	hsa-miR-3148	CLIP-seq
MIRT1525406	hsa-miR-3671	CLIP-seq
MIRT2158768	hsa-miR-3978	CLIP-seq
MIRT2158769	hsa-miR-4307	CLIP-seq
MIRT2158770	hsa-miR-4782-3p	CLIP-seq
MIRT1525428	hsa-miR-499a-5p	CLIP-seq
MIRT2158771	hsa-miR-570	CLIP-seq
MIRT2378196	hsa-miR-1255a	CLIP-seq
MIRT2378197	hsa-miR-1255b	CLIP-seq
MIRT2158764	hsa-miR-146a	CLIP-seq
MIRT2158765	hsa-miR-146b-5p	CLIP-seq
MIRT2378198	hsa-miR-2277-3p	CLIP-seq
MIRT2378199	hsa-miR-34b	CLIP-seq
MIRT2378200	hsa-miR-34c-3p	CLIP-seq
MIRT1525406	hsa-miR-3671	CLIP-seq
MIRT2378201	hsa-miR-3919	CLIP-seq
MIRT2378202	hsa-miR-4330	CLIP-seq
MIRT2378203	hsa-miR-4756-3p	CLIP-seq
MIRT2378204	hsa-miR-4797-5p	CLIP-seq
MIRT1525428	hsa-miR-499a-5p	CLIP-seq
MIRT2378205	hsa-miR-922	CLIP-seq
MIRT2670495	hsa-miR-1208	CLIP-seq
MIRT1525388	hsa-miR-124	CLIP-seq
MIRT2670496	hsa-miR-1245	CLIP-seq
MIRT2670497	hsa-miR-1253	CLIP-seq
MIRT2670498	hsa-miR-1264	CLIP-seq
MIRT2670499	hsa-miR-1321	CLIP-seq
MIRT2670500	hsa-miR-181a	CLIP-seq
MIRT2670501	hsa-miR-181b	CLIP-seq
MIRT2670502	hsa-miR-181c	CLIP-seq
MIRT2670503	hsa-miR-181d	CLIP-seq
MIRT1525393	hsa-miR-186	CLIP-seq
MIRT2670504	hsa-miR-190	CLIP-seq
MIRT2670505	hsa-miR-190b	CLIP-seq
MIRT2670506	hsa-miR-204	CLIP-seq
MIRT2670507	hsa-miR-211	CLIP-seq
MIRT2378198	hsa-miR-2277-3p	CLIP-seq
MIRT1525397	hsa-miR-2682	CLIP-seq
MIRT2670508	hsa-miR-3064-3p	CLIP-seq
MIRT2670509	hsa-miR-3122	CLIP-seq
MIRT1525399	hsa-miR-3133	CLIP-seq
MIRT2670510	hsa-miR-3160-3p	CLIP-seq
MIRT2670511	hsa-miR-3162-5p	CLIP-seq
MIRT2670512	hsa-miR-3200-5p	CLIP-seq
MIRT2670513	hsa-miR-323-3p	CLIP-seq
MIRT2670514	hsa-miR-337-3p	CLIP-seq
MIRT1525401	hsa-miR-34a	CLIP-seq
MIRT1525402	hsa-miR-34c-5p	CLIP-seq
MIRT2670515	hsa-miR-3606	CLIP-seq
MIRT1525403	hsa-miR-3617	CLIP-seq
MIRT2670516	hsa-miR-3662	CLIP-seq
MIRT1525408	hsa-miR-3714	CLIP-seq
MIRT2670517	hsa-miR-376c	CLIP-seq
MIRT1525409	hsa-miR-3910	CLIP-seq
MIRT2670518	hsa-miR-3913-5p	CLIP-seq
MIRT1525412	hsa-miR-4282	CLIP-seq
MIRT2670519	hsa-miR-4420	CLIP-seq
MIRT2670520	hsa-miR-4427	CLIP-seq
MIRT1525418	hsa-miR-4477b	CLIP-seq
MIRT2670521	hsa-miR-4487	CLIP-seq
MIRT2670522	hsa-miR-4494	CLIP-seq
MIRT1525420	hsa-miR-449a	CLIP-seq
MIRT1525421	hsa-miR-449b	CLIP-seq
MIRT1525422	hsa-miR-449c	CLIP-seq
MIRT1525423	hsa-miR-4506	CLIP-seq
MIRT2670523	hsa-miR-4666-5p	CLIP-seq
MIRT1525425	hsa-miR-4680-3p	CLIP-seq
MIRT2670524	hsa-miR-4708-5p	CLIP-seq
MIRT2670525	hsa-miR-4715-3p	CLIP-seq
MIRT2670526	hsa-miR-4717-3p	CLIP-seq
MIRT1525426	hsa-miR-4728-3p	CLIP-seq
MIRT2670527	hsa-miR-4739	CLIP-seq
MIRT2670528	hsa-miR-4755-5p	CLIP-seq
MIRT2670529	hsa-miR-4756-5p	CLIP-seq
MIRT2670530	hsa-miR-4780	CLIP-seq
MIRT2670531	hsa-miR-4789-3p	CLIP-seq
MIRT2670532	hsa-miR-4789-5p	CLIP-seq
MIRT1525428	hsa-miR-499a-5p	CLIP-seq
MIRT1525430	hsa-miR-506	CLIP-seq
MIRT2670533	hsa-miR-514	CLIP-seq
MIRT2670534	hsa-miR-514b-3p	CLIP-seq
MIRT1525432	hsa-miR-548u	CLIP-seq
MIRT1525433	hsa-miR-555	CLIP-seq
MIRT2670535	hsa-miR-558	CLIP-seq
MIRT2670536	hsa-miR-578	CLIP-seq
MIRT2670537	hsa-miR-590-3p	CLIP-seq
MIRT2670538	hsa-miR-623	CLIP-seq
MIRT1525437	hsa-miR-641	CLIP-seq
MIRT2670539	hsa-miR-642b	CLIP-seq
MIRT2670540	hsa-miR-656	CLIP-seq
MIRT2670541	hsa-miR-921	CLIP-seq
MIRT2670495	hsa-miR-1208	CLIP-seq
MIRT1525388	hsa-miR-124	CLIP-seq
MIRT2670497	hsa-miR-1253	CLIP-seq
MIRT2670498	hsa-miR-1264	CLIP-seq
MIRT2670499	hsa-miR-1321	CLIP-seq
MIRT2158764	hsa-miR-146a	CLIP-seq
MIRT2158765	hsa-miR-146b-5p	CLIP-seq
MIRT2670506	hsa-miR-204	CLIP-seq
MIRT2670507	hsa-miR-211	CLIP-seq
MIRT2378198	hsa-miR-2277-3p	CLIP-seq
MIRT1525397	hsa-miR-2682	CLIP-seq
MIRT2670509	hsa-miR-3122	CLIP-seq
MIRT2670510	hsa-miR-3160-3p	CLIP-seq
MIRT2670511	hsa-miR-3162-5p	CLIP-seq
MIRT1525401	hsa-miR-34a	CLIP-seq
MIRT1525402	hsa-miR-34c-5p	CLIP-seq
MIRT1525403	hsa-miR-3617	CLIP-seq
MIRT1525408	hsa-miR-3714	CLIP-seq
MIRT2670517	hsa-miR-376c	CLIP-seq
MIRT1525409	hsa-miR-3910	CLIP-seq
MIRT2670518	hsa-miR-3913-5p	CLIP-seq
MIRT2696033	hsa-miR-410	CLIP-seq
MIRT2670519	hsa-miR-4420	CLIP-seq
MIRT1525418	hsa-miR-4477b	CLIP-seq
MIRT2670521	hsa-miR-4487	CLIP-seq
MIRT1525420	hsa-miR-449a	CLIP-seq
MIRT1525421	hsa-miR-449b	CLIP-seq
MIRT1525422	hsa-miR-449c	CLIP-seq
MIRT2670523	hsa-miR-4666-5p	CLIP-seq
MIRT1525425	hsa-miR-4680-3p	CLIP-seq
MIRT2670524	hsa-miR-4708-5p	CLIP-seq
MIRT1525426	hsa-miR-4728-3p	CLIP-seq
MIRT2696034	hsa-miR-4729	CLIP-seq
MIRT2670527	hsa-miR-4739	CLIP-seq
MIRT2670528	hsa-miR-4755-5p	CLIP-seq
MIRT2670529	hsa-miR-4756-5p	CLIP-seq
MIRT2670530	hsa-miR-4780	CLIP-seq
MIRT2670531	hsa-miR-4789-3p	CLIP-seq
MIRT1525430	hsa-miR-506	CLIP-seq
MIRT2670533	hsa-miR-514	CLIP-seq
MIRT2670534	hsa-miR-514b-3p	CLIP-seq
MIRT1525432	hsa-miR-548u	CLIP-seq
MIRT2670535	hsa-miR-558	CLIP-seq
MIRT2670536	hsa-miR-578	CLIP-seq
MIRT2696035	hsa-miR-589	CLIP-seq
MIRT2670538	hsa-miR-623	CLIP-seq
MIRT1525437	hsa-miR-641	CLIP-seq
MIRT2670539	hsa-miR-642b	CLIP-seq

Gene ontology (GO) Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0007284	Process	Spermatogonial cell division	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

Other IDs

• MIM: 300627
• HGNC: 21039
• e!Ensembl: ENSG00000173275

Protein

• UniProt ID: Q6P9G9
• Protein name: Zinc finger protein 449 (Zinc finger and SCAN domain-containing protein 19)
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	463 → 485	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	323 → 345	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	435 → 457	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	379 → 401	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	351 → 373	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	407 → 429	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	491 → 513	Zinc finger, C2H2 type	Domain
  PF02023	SCAN	26 → 115	SCAN domain	Domain

• Sequence:

  MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYREAAGPHEAFNKLWELCCQWLK
  PKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLIEDLQRELEIPEQQVD
  MHDMLLEELAPVGTAHIPPTMHLESPALQVMGPAQEAPVAEAWIPQAGPPELNYGATGEC
  QNFLDPGYPLPKLDMNFSLENREEPWVKELQDSKEMKQLLDSKIGFEIGIENEEDTSKQK
  KMETMYPFIVTLEGNALQGPILQKDYVQLENQWETPPEDLQTDLAKLVDQQNPTLGETPE
  NSNLEEPLNPKPHKKKSPGEKPHRCPQCGKCFARKSQLTGHQRIHSGEEPHKCPECGKRF
  LRSSDLYRHQRLHTGERPYECTVCKKRFTRRSHLIGHQRTHSEEETYKCLECGKSFCHGS
  SLKRHLKTHTGEKPHRCHNCGKSFSRLTALTLHQRTHTEERPFKCNYCGKSFRQRPSLVI
  HLRIHTGEKPYKCTHCSKSFRQRAGLIMHQVTHFRGLI

• Sequence length: 518

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Short stature	Uncertain significance	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Related Genes

No strongly related genes found yet for ZNF449.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZNF449.