ZNF444 (zinc finger protein 444)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 55311
• Gene name: Zinc finger protein 444
• Gene symbol: ZNF444
• Synonyms (NCBI Gene): EZF-2, EZF2, ZSCAN17
• Chromosome: 19
• Chromosome location: 19q13.43
• Summary: This gene encodes a zinc finger protein which activates transcription of a scavenger receptor gene involved in the degradation of acetylated low density lipoprotein (Ac-LDL) (PMID: 11978792). This gene is located in a cluster of zinc finger genes on chrom

miRNA Show/Hide all (134)

miRTarBase ID	miRNA	Experiments	Reference
MIRT451260	hsa-miR-3173-3p	PAR-CLIP	23592263
MIRT451258	hsa-miR-6891-5p	PAR-CLIP	23592263
MIRT451257	hsa-miR-5197-3p	PAR-CLIP	23592263
MIRT451256	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT451255	hsa-miR-6886-5p	PAR-CLIP	23592263
MIRT451254	hsa-miR-1253	PAR-CLIP	23592263
MIRT451253	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT451252	hsa-miR-4784	PAR-CLIP	23592263
MIRT451251	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT451250	hsa-miR-4533	PAR-CLIP	23592263
MIRT451249	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT451247	hsa-miR-4306	PAR-CLIP	23592263
MIRT451248	hsa-miR-4644	PAR-CLIP	23592263
MIRT451246	hsa-miR-765	PAR-CLIP	23592263
MIRT451245	hsa-miR-4747-5p	PAR-CLIP	23592263
MIRT451244	hsa-miR-5196-5p	PAR-CLIP	23592263
MIRT451243	hsa-miR-4271	PAR-CLIP	23592263
MIRT451242	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT451241	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT451240	hsa-miR-625-5p	PAR-CLIP	23592263
MIRT451239	hsa-miR-6795-5p	PAR-CLIP	23592263
MIRT451238	hsa-miR-6887-5p	PAR-CLIP	23592263
MIRT451236	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT451237	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT451235	hsa-miR-3125	PAR-CLIP	23592263
MIRT451234	hsa-miR-3916	PAR-CLIP	23592263
MIRT451233	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT451232	hsa-miR-4779	PAR-CLIP	23592263
MIRT451231	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT451230	hsa-miR-4436b-3p	PAR-CLIP	23592263
MIRT451229	hsa-miR-4632-5p	PAR-CLIP	23592263
MIRT451228	hsa-miR-6735-5p	PAR-CLIP	23592263
MIRT451227	hsa-miR-6879-5p	PAR-CLIP	23592263
MIRT451226	hsa-miR-7843-5p	PAR-CLIP	23592263
MIRT451225	hsa-miR-4802-5p	PAR-CLIP	23592263
MIRT451224	hsa-miR-4270	PAR-CLIP	23592263
MIRT451223	hsa-miR-4441	PAR-CLIP	23592263
MIRT451222	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT451221	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT451220	hsa-miR-7154-3p	PAR-CLIP	23592263
MIRT451219	hsa-miR-6894-5p	PAR-CLIP	23592263
MIRT451218	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT451217	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT451216	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT451214	hsa-miR-8085	PAR-CLIP	23592263
MIRT451215	hsa-miR-6721-5p	PAR-CLIP	23592263
MIRT451260	hsa-miR-3173-3p	PAR-CLIP	23592263
MIRT451258	hsa-miR-6891-5p	PAR-CLIP	23592263
MIRT451257	hsa-miR-5197-3p	PAR-CLIP	23592263
MIRT451256	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT451255	hsa-miR-6886-5p	PAR-CLIP	23592263
MIRT451254	hsa-miR-1253	PAR-CLIP	23592263
MIRT451253	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT451252	hsa-miR-4784	PAR-CLIP	23592263
MIRT451251	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT451250	hsa-miR-4533	PAR-CLIP	23592263
MIRT451249	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT451247	hsa-miR-4306	PAR-CLIP	23592263
MIRT451248	hsa-miR-4644	PAR-CLIP	23592263
MIRT451246	hsa-miR-765	PAR-CLIP	23592263
MIRT451245	hsa-miR-4747-5p	PAR-CLIP	23592263
MIRT451244	hsa-miR-5196-5p	PAR-CLIP	23592263
MIRT451243	hsa-miR-4271	PAR-CLIP	23592263
MIRT451242	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT451241	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT451240	hsa-miR-625-5p	PAR-CLIP	23592263
MIRT451239	hsa-miR-6795-5p	PAR-CLIP	23592263
MIRT451238	hsa-miR-6887-5p	PAR-CLIP	23592263
MIRT451236	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT451237	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT451235	hsa-miR-3125	PAR-CLIP	23592263
MIRT451234	hsa-miR-3916	PAR-CLIP	23592263
MIRT451233	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT451232	hsa-miR-4779	PAR-CLIP	23592263
MIRT451231	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT451230	hsa-miR-4436b-3p	PAR-CLIP	23592263
MIRT451229	hsa-miR-4632-5p	PAR-CLIP	23592263
MIRT451228	hsa-miR-6735-5p	PAR-CLIP	23592263
MIRT451227	hsa-miR-6879-5p	PAR-CLIP	23592263
MIRT451226	hsa-miR-7843-5p	PAR-CLIP	23592263
MIRT451225	hsa-miR-4802-5p	PAR-CLIP	23592263
MIRT451224	hsa-miR-4270	PAR-CLIP	23592263
MIRT451223	hsa-miR-4441	PAR-CLIP	23592263
MIRT451222	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT451221	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT451220	hsa-miR-7154-3p	PAR-CLIP	23592263
MIRT451219	hsa-miR-6894-5p	PAR-CLIP	23592263
MIRT451218	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT451217	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT451216	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT451214	hsa-miR-8085	PAR-CLIP	23592263
MIRT451215	hsa-miR-6721-5p	PAR-CLIP	23592263
MIRT1525169	hsa-miR-1200	CLIP-seq
MIRT1525170	hsa-miR-128	CLIP-seq
MIRT1525171	hsa-miR-1321	CLIP-seq
MIRT1525172	hsa-miR-3126-5p	CLIP-seq
MIRT1525173	hsa-miR-3164	CLIP-seq
MIRT1525174	hsa-miR-329	CLIP-seq
MIRT1525175	hsa-miR-361-3p	CLIP-seq
MIRT1525176	hsa-miR-3618	CLIP-seq
MIRT1525177	hsa-miR-362-3p	CLIP-seq
MIRT1525178	hsa-miR-384	CLIP-seq
MIRT1525179	hsa-miR-3941	CLIP-seq
MIRT1525180	hsa-miR-3978	CLIP-seq
MIRT1525181	hsa-miR-4324	CLIP-seq
MIRT1525182	hsa-miR-4419a	CLIP-seq
MIRT1525183	hsa-miR-4476	CLIP-seq
MIRT1525184	hsa-miR-4510	CLIP-seq
MIRT1525185	hsa-miR-451b	CLIP-seq
MIRT1525186	hsa-miR-4696	CLIP-seq
MIRT1525187	hsa-miR-4739	CLIP-seq
MIRT1525188	hsa-miR-4756-5p	CLIP-seq
MIRT1525189	hsa-miR-486-3p	CLIP-seq
MIRT1525190	hsa-miR-513a-5p	CLIP-seq
MIRT1525191	hsa-miR-532-5p	CLIP-seq
MIRT1525192	hsa-miR-544b	CLIP-seq
MIRT1525193	hsa-miR-556-3p	CLIP-seq
MIRT1525194	hsa-miR-571	CLIP-seq
MIRT1525195	hsa-miR-603	CLIP-seq
MIRT1525170	hsa-miR-128	CLIP-seq
MIRT1525171	hsa-miR-1321	CLIP-seq
MIRT1525173	hsa-miR-3164	CLIP-seq
MIRT2158631	hsa-miR-3176	CLIP-seq
MIRT2158632	hsa-miR-3922-3p	CLIP-seq
MIRT1525187	hsa-miR-4739	CLIP-seq
MIRT1525188	hsa-miR-4756-5p	CLIP-seq
MIRT1525193	hsa-miR-556-3p	CLIP-seq
MIRT2158633	hsa-miR-625	CLIP-seq
MIRT2378147	hsa-miR-185	CLIP-seq
MIRT1525175	hsa-miR-361-3p	CLIP-seq
MIRT2378148	hsa-miR-4505	CLIP-seq
MIRT2378149	hsa-miR-485-5p	CLIP-seq
MIRT2378150	hsa-miR-539	CLIP-seq
MIRT2158633	hsa-miR-625	CLIP-seq

Gene ontology (GO) Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	28514442, 32296183, 32814053
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IEA

Other IDs

• MIM: 607874
• HGNC: 16052
• e!Ensembl: ENSG00000167685

Protein

• UniProt ID: Q8N0Y2
• Protein name: Zinc finger protein 444 (Endothelial zinc finger protein 2) (EZF-2) (Zinc finger and SCAN domain-containing protein 17)
• Protein function: Transcriptional regulator. Binds to the 5'-flanking critical region of the SCARF1 promoter.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	207 → 229	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	278 → 300	Zinc finger, C2H2 type	Domain
  PF02023	SCAN	17 → 103	SCAN domain	Domain

• Sequence:

  MEVAVPVKQEAEGLALDSPWHRFRRFHLGDAPGPREALGLLRALCRDWLRPEVHTKEQML
  ELLVLEQFLSALPADTQAWVCSRQPQSGEEAVALLEELWGPAASPDGSSATRVPQDVTQG
  PGATGGKEDSGMIPLAGTAPGAEGPAPGDSQAVRPYKQEPSSPPLAPGLPAFLAAPGTTS
  CPECGKTSLKPAHLLRHRQSHSGEKPHACPECGKAFRRKEHLRRHRDTHPGSPGSPGPAL
  RPLPAREKPHACCECGKTFYWREHLVRHRKTHSGARPFACWECGKGFGRREHVLRHQRIH
  GRAAASAQGAVAPGPDGGGPFPPWPLG

• Sequence length: 327

Related Genes

No strongly related genes found yet for ZNF444.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZNF444.