ZNF425 (zinc finger protein 425)

Download as csv Download as pdf

Log in to save this analysis

Save This Analysis

Title Project / Tag (optional) Note (optional)

Cancel Save

On this page

Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 155054
• Gene name: Zinc finger protein 425
• Gene symbol: ZNF425
• Synonyms (NCBI Gene): -
• Chromosome: 7
• Chromosome location: 7q36.1

miRNA Show/Hide all (127)

miRTarBase ID	miRNA	Experiments	Reference
MIRT572657	hsa-miR-1306-3p	PAR-CLIP	20371350
MIRT572656	hsa-miR-6503-3p	PAR-CLIP	20371350
MIRT572655	hsa-miR-4709-3p	PAR-CLIP	20371350
MIRT572653	hsa-miR-1269a	PAR-CLIP	20371350
MIRT572654	hsa-miR-1269b	PAR-CLIP	20371350
MIRT572652	hsa-miR-5009-5p	PAR-CLIP	20371350
MIRT572651	hsa-miR-8058	PAR-CLIP	20371350
MIRT572650	hsa-miR-4529-3p	PAR-CLIP	20371350
MIRT572657	hsa-miR-1306-3p	PAR-CLIP	20371350
MIRT572656	hsa-miR-6503-3p	PAR-CLIP	20371350
MIRT572655	hsa-miR-4709-3p	PAR-CLIP	20371350
MIRT572653	hsa-miR-1269a	PAR-CLIP	20371350
MIRT572654	hsa-miR-1269b	PAR-CLIP	20371350
MIRT572652	hsa-miR-5009-5p	PAR-CLIP	20371350
MIRT572651	hsa-miR-8058	PAR-CLIP	20371350
MIRT572650	hsa-miR-4529-3p	PAR-CLIP	20371350
MIRT1524309	hsa-miR-1184	CLIP-seq
MIRT1524310	hsa-miR-1224-3p	CLIP-seq
MIRT1524311	hsa-miR-1260	CLIP-seq
MIRT1524312	hsa-miR-1260b	CLIP-seq
MIRT1524313	hsa-miR-1280	CLIP-seq
MIRT1524314	hsa-miR-1285	CLIP-seq
MIRT1524315	hsa-miR-1343	CLIP-seq
MIRT1524316	hsa-miR-194	CLIP-seq
MIRT1524317	hsa-miR-24	CLIP-seq
MIRT1524318	hsa-miR-3064-5p	CLIP-seq
MIRT1524319	hsa-miR-3156-5p	CLIP-seq
MIRT1524320	hsa-miR-3179	CLIP-seq
MIRT1524321	hsa-miR-3187-5p	CLIP-seq
MIRT1524322	hsa-miR-3190	CLIP-seq
MIRT1524323	hsa-miR-3194-3p	CLIP-seq
MIRT1524324	hsa-miR-3617	CLIP-seq
MIRT1524325	hsa-miR-3681	CLIP-seq
MIRT1524326	hsa-miR-378g	CLIP-seq
MIRT1524327	hsa-miR-3915	CLIP-seq
MIRT1524328	hsa-miR-3928	CLIP-seq
MIRT1524329	hsa-miR-3937	CLIP-seq
MIRT1524330	hsa-miR-4252	CLIP-seq
MIRT1524331	hsa-miR-4284	CLIP-seq
MIRT1524332	hsa-miR-4314	CLIP-seq
MIRT1524333	hsa-miR-4326	CLIP-seq
MIRT1524334	hsa-miR-4418	CLIP-seq
MIRT1524335	hsa-miR-4427	CLIP-seq
MIRT1524336	hsa-miR-4437	CLIP-seq
MIRT1524337	hsa-miR-4438	CLIP-seq
MIRT1524338	hsa-miR-4486	CLIP-seq
MIRT1524339	hsa-miR-4674	CLIP-seq
MIRT1524340	hsa-miR-4680-3p	CLIP-seq
MIRT1524341	hsa-miR-4687-3p	CLIP-seq
MIRT1524342	hsa-miR-4703-3p	CLIP-seq
MIRT1524343	hsa-miR-4729	CLIP-seq
MIRT1524344	hsa-miR-4762-3p	CLIP-seq
MIRT1524345	hsa-miR-509-3-5p	CLIP-seq
MIRT1524346	hsa-miR-5095	CLIP-seq
MIRT1524347	hsa-miR-509-5p	CLIP-seq
MIRT1524348	hsa-miR-532-3p	CLIP-seq
MIRT1524349	hsa-miR-612	CLIP-seq
MIRT1524350	hsa-miR-641	CLIP-seq
MIRT1524351	hsa-miR-7	CLIP-seq
MIRT1524315	hsa-miR-1343	CLIP-seq
MIRT2158437	hsa-miR-1976	CLIP-seq
MIRT1524326	hsa-miR-378g	CLIP-seq
MIRT1524336	hsa-miR-4437	CLIP-seq
MIRT1524339	hsa-miR-4674	CLIP-seq
MIRT2158438	hsa-miR-4714-3p	CLIP-seq
MIRT2158439	hsa-miR-4722-3p	CLIP-seq
MIRT2377951	hsa-miR-122	CLIP-seq
MIRT1524315	hsa-miR-1343	CLIP-seq
MIRT2377952	hsa-miR-150	CLIP-seq
MIRT2158437	hsa-miR-1976	CLIP-seq
MIRT2377953	hsa-miR-3124-3p	CLIP-seq
MIRT2377954	hsa-miR-3135b	CLIP-seq
MIRT1524323	hsa-miR-3194-3p	CLIP-seq
MIRT2377955	hsa-miR-337-3p	CLIP-seq
MIRT2377956	hsa-miR-3650	CLIP-seq
MIRT2377957	hsa-miR-3652	CLIP-seq
MIRT2377958	hsa-miR-3685	CLIP-seq
MIRT1524326	hsa-miR-378g	CLIP-seq
MIRT2377959	hsa-miR-384	CLIP-seq
MIRT2377960	hsa-miR-3973	CLIP-seq
MIRT2377961	hsa-miR-4430	CLIP-seq
MIRT1524336	hsa-miR-4437	CLIP-seq
MIRT2377962	hsa-miR-4461	CLIP-seq
MIRT1524339	hsa-miR-4674	CLIP-seq
MIRT2158438	hsa-miR-4714-3p	CLIP-seq
MIRT2158439	hsa-miR-4722-3p	CLIP-seq
MIRT2377963	hsa-miR-4757-3p	CLIP-seq
MIRT2377964	hsa-miR-562	CLIP-seq
MIRT2377965	hsa-miR-564	CLIP-seq
MIRT2377951	hsa-miR-122	CLIP-seq
MIRT1524317	hsa-miR-24	CLIP-seq
MIRT2377954	hsa-miR-3135b	CLIP-seq
MIRT2377956	hsa-miR-3650	CLIP-seq
MIRT2377957	hsa-miR-3652	CLIP-seq
MIRT1524331	hsa-miR-4284	CLIP-seq
MIRT2377961	hsa-miR-4430	CLIP-seq
MIRT1524315	hsa-miR-1343	CLIP-seq
MIRT1524326	hsa-miR-378g	CLIP-seq
MIRT1524336	hsa-miR-4437	CLIP-seq
MIRT1524339	hsa-miR-4674	CLIP-seq
MIRT1524315	hsa-miR-1343	CLIP-seq
MIRT2158437	hsa-miR-1976	CLIP-seq
MIRT1524326	hsa-miR-378g	CLIP-seq
MIRT1524336	hsa-miR-4437	CLIP-seq
MIRT1524339	hsa-miR-4674	CLIP-seq
MIRT2158439	hsa-miR-4722-3p	CLIP-seq
MIRT1524315	hsa-miR-1343	CLIP-seq
MIRT2158437	hsa-miR-1976	CLIP-seq
MIRT2377953	hsa-miR-3124-3p	CLIP-seq
MIRT2696019	hsa-miR-3126-5p	CLIP-seq
MIRT2696020	hsa-miR-3136-5p	CLIP-seq
MIRT2377955	hsa-miR-337-3p	CLIP-seq
MIRT2377958	hsa-miR-3685	CLIP-seq
MIRT1524326	hsa-miR-378g	CLIP-seq
MIRT2377959	hsa-miR-384	CLIP-seq
MIRT2696021	hsa-miR-4419a	CLIP-seq
MIRT1524336	hsa-miR-4437	CLIP-seq
MIRT2696022	hsa-miR-4439	CLIP-seq
MIRT2377962	hsa-miR-4461	CLIP-seq
MIRT2696023	hsa-miR-4510	CLIP-seq
MIRT1524339	hsa-miR-4674	CLIP-seq
MIRT2158439	hsa-miR-4722-3p	CLIP-seq
MIRT2696024	hsa-miR-4753-3p	CLIP-seq
MIRT2377963	hsa-miR-4757-3p	CLIP-seq
MIRT2377965	hsa-miR-564	CLIP-seq
MIRT2696025	hsa-miR-593	CLIP-seq
MIRT2696026	hsa-miR-943	CLIP-seq

Gene ontology (GO) Show/Hide all (15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	21266108
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IDA	21266108
GO:0005737	Component	Cytoplasm	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0045892	Process	Negative regulation of DNA-templated transcription	IDA	21266108
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 619507
• HGNC: 20690
• e!Ensembl: ENSG00000204947

Protein

• UniProt ID: Q6IV72
• Protein name: Zinc finger protein 425
• Protein function: Acts as a transcriptional repressor.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	358 → 380	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	638 → 660	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	274 → 296	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	582 → 604	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	526 → 548	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	498 → 520	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	610 → 632	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	722 → 744	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	302 → 324	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	470 → 492	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	414 → 436	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	666 → 688	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	386 → 408	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	694 → 716	Zinc finger, C2H2 type	Domain
  PF01352	KRAB	8 → 49	KRAB box	Family

• Sequence:

  MAEPASVTVTFDDVALYFSEQEWEILEKWQKQMYKQEMKTNYETLDSLGYAFSKPDLITW
  MEQGRMLLISEQGCLDKTRRTTSPPTDEQLNMKNTGKLLCFDDEGTPRTKEEDCRLNGPQ
  KQDLCAALRGKERKILLAQTATFQSPSLRETEILNKKVSITAYDPDKKDLRHKPRETPGR
  LEIPTGPRCYSCYVCRKVFQVRRDLLKHKRSHSKSQLCRYPKYKNSSRGKSELRRTQRLL
  CQKKRFQCSECEKSYFLKGSLVTHQVVHTGQRPYPCPECDKTFRYRANLKKHLCLHRGER
  PFCCGECGRAFVQQCELTEHLRLHSGEKPFQCPQCDRCFRLKRGMKVHLTQHSGKRPFHC
  PECGRSFSRKAALKTHQRTHSEEKPFSCGECGRKFIYKIKLDEHIRVHTGEKPFSCPECN
  KSFRLKRSLKAHGLQHIGKRPFQCPECSRGFFWRNAMRAHQRLHSEQKPFPCAECGKRFT
  RPSKLACHTRVHDRQKEFPCGECKKTFSQQSRLTQHLKVHTTEKPFSCAECGRSFRRRAH
  LTEHTRLHSGEEPFQCPECDKSFSWKASMKFHQRMHRDEKPFACGECDKTYTHQSQLTEH
  LRLHSGEKPYQCPECEKTFRLKGNLKSHLLQHSGQKPFSCVMCGKSFTQQYRLTEHIRVH
  SGEKPFQCPECDKSYCIRGSLKVHLYKHSGERPFQCPECGKGFLQKRSLKAHLCLHSGER
  PFSCDECGRSFTYVGALKTHIAVHAKEKPSSL

• Sequence length: 752

Pathways

Reactome Pathway:

Generic Transcription Pathway

Related Genes

No strongly related genes found yet for ZNF425.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZNF425.