ZNF419 (zinc finger protein 419)

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Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 79744
• Gene name: Zinc finger protein 419
• Gene symbol: ZNF419
• Synonyms (NCBI Gene): ZAPHIR, ZNF419A
• Chromosome: 19
• Chromosome location: 19q13.43

miRNA Show/Hide all (214)

miRTarBase ID	miRNA	Experiments	Reference
MIRT709164	hsa-miR-181a-2-3p	HITS-CLIP	19536157
MIRT709163	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT709161	hsa-miR-4299	HITS-CLIP	19536157
MIRT709162	hsa-miR-548q	HITS-CLIP	19536157
MIRT709159	hsa-miR-4456	HITS-CLIP	19536157
MIRT709160	hsa-miR-7978	HITS-CLIP	19536157
MIRT709158	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT709157	hsa-miR-4436b-5p	HITS-CLIP	19536157
MIRT709156	hsa-miR-3692-3p	HITS-CLIP	19536157
MIRT709164	hsa-miR-181a-2-3p	HITS-CLIP	19536157
MIRT709163	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT709161	hsa-miR-4299	HITS-CLIP	19536157
MIRT709162	hsa-miR-548q	HITS-CLIP	19536157
MIRT709159	hsa-miR-4456	HITS-CLIP	19536157
MIRT709160	hsa-miR-7978	HITS-CLIP	19536157
MIRT709158	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT709157	hsa-miR-4436b-5p	HITS-CLIP	19536157
MIRT709156	hsa-miR-3692-3p	HITS-CLIP	19536157
MIRT709164	hsa-miR-181a-2-3p	HITS-CLIP	19536157
MIRT709163	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT709161	hsa-miR-4299	HITS-CLIP	19536157
MIRT709162	hsa-miR-548q	HITS-CLIP	19536157
MIRT709159	hsa-miR-4456	HITS-CLIP	19536157
MIRT709160	hsa-miR-7978	HITS-CLIP	19536157
MIRT709158	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT709157	hsa-miR-4436b-5p	HITS-CLIP	19536157
MIRT709156	hsa-miR-3692-3p	HITS-CLIP	19536157
MIRT709164	hsa-miR-181a-2-3p	HITS-CLIP	19536157
MIRT709163	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT709161	hsa-miR-4299	HITS-CLIP	19536157
MIRT709162	hsa-miR-548q	HITS-CLIP	19536157
MIRT709159	hsa-miR-4456	HITS-CLIP	19536157
MIRT709160	hsa-miR-7978	HITS-CLIP	19536157
MIRT709158	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT709157	hsa-miR-4436b-5p	HITS-CLIP	19536157
MIRT709156	hsa-miR-3692-3p	HITS-CLIP	19536157
MIRT679035	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT679034	hsa-miR-5007-5p	HITS-CLIP	23824327
MIRT679033	hsa-miR-4794	HITS-CLIP	23824327
MIRT679032	hsa-miR-664a-5p	HITS-CLIP	23824327
MIRT679031	hsa-miR-149-5p	HITS-CLIP	23824327
MIRT679030	hsa-miR-3064-5p	HITS-CLIP	23824327
MIRT679029	hsa-miR-6504-5p	HITS-CLIP	23824327
MIRT679028	hsa-miR-4524a-3p	HITS-CLIP	23824327
MIRT679027	hsa-miR-3119	HITS-CLIP	23824327
MIRT679026	hsa-miR-3672	HITS-CLIP	23824327
MIRT679025	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT679024	hsa-miR-8055	HITS-CLIP	23824327
MIRT679023	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT662101	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT662100	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT662099	hsa-miR-4532	HITS-CLIP	23824327
MIRT662098	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT662097	hsa-miR-1281	HITS-CLIP	23824327
MIRT662096	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT662095	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT662094	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT662093	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT662092	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT662091	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT662090	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT662089	hsa-miR-4284	HITS-CLIP	23824327
MIRT662088	hsa-miR-4437	HITS-CLIP	23824327
MIRT679023	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT679027	hsa-miR-3119	HITS-CLIP	27418678
MIRT679026	hsa-miR-3672	HITS-CLIP	27418678
MIRT679028	hsa-miR-4524a-3p	HITS-CLIP	27418678
MIRT679025	hsa-miR-6864-3p	HITS-CLIP	27418678
MIRT679024	hsa-miR-8055	HITS-CLIP	27418678
MIRT679023	hsa-miR-129-5p	HITS-CLIP	28735896
MIRT679027	hsa-miR-3119	HITS-CLIP	28735896
MIRT679026	hsa-miR-3672	HITS-CLIP	28735896
MIRT679028	hsa-miR-4524a-3p	HITS-CLIP	28735896
MIRT679025	hsa-miR-6864-3p	HITS-CLIP	28735896
MIRT679024	hsa-miR-8055	HITS-CLIP	28735896
MIRT709164	hsa-miR-181a-2-3p	HITS-CLIP	19536157
MIRT709163	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT709161	hsa-miR-4299	HITS-CLIP	19536157
MIRT709162	hsa-miR-548q	HITS-CLIP	19536157
MIRT709159	hsa-miR-4456	HITS-CLIP	19536157
MIRT709160	hsa-miR-7978	HITS-CLIP	19536157
MIRT709158	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT709157	hsa-miR-4436b-5p	HITS-CLIP	19536157
MIRT709156	hsa-miR-3692-3p	HITS-CLIP	19536157
MIRT709164	hsa-miR-181a-2-3p	HITS-CLIP	19536157
MIRT709163	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT709161	hsa-miR-4299	HITS-CLIP	19536157
MIRT709162	hsa-miR-548q	HITS-CLIP	19536157
MIRT709159	hsa-miR-4456	HITS-CLIP	19536157
MIRT709160	hsa-miR-7978	HITS-CLIP	19536157
MIRT709158	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT709157	hsa-miR-4436b-5p	HITS-CLIP	19536157
MIRT709156	hsa-miR-3692-3p	HITS-CLIP	19536157
MIRT709164	hsa-miR-181a-2-3p	HITS-CLIP	19536157
MIRT709163	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT709161	hsa-miR-4299	HITS-CLIP	19536157
MIRT709162	hsa-miR-548q	HITS-CLIP	19536157
MIRT709159	hsa-miR-4456	HITS-CLIP	19536157
MIRT709160	hsa-miR-7978	HITS-CLIP	19536157
MIRT709158	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT709157	hsa-miR-4436b-5p	HITS-CLIP	19536157
MIRT709156	hsa-miR-3692-3p	HITS-CLIP	19536157
MIRT709164	hsa-miR-181a-2-3p	HITS-CLIP	19536157
MIRT709163	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT709161	hsa-miR-4299	HITS-CLIP	19536157
MIRT709162	hsa-miR-548q	HITS-CLIP	19536157
MIRT709159	hsa-miR-4456	HITS-CLIP	19536157
MIRT709160	hsa-miR-7978	HITS-CLIP	19536157
MIRT709158	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT709157	hsa-miR-4436b-5p	HITS-CLIP	19536157
MIRT709156	hsa-miR-3692-3p	HITS-CLIP	19536157
MIRT679035	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT679034	hsa-miR-5007-5p	HITS-CLIP	23824327
MIRT679033	hsa-miR-4794	HITS-CLIP	23824327
MIRT679032	hsa-miR-664a-5p	HITS-CLIP	23824327
MIRT679031	hsa-miR-149-5p	HITS-CLIP	23824327
MIRT679030	hsa-miR-3064-5p	HITS-CLIP	23824327
MIRT679029	hsa-miR-6504-5p	HITS-CLIP	23824327
MIRT679028	hsa-miR-4524a-3p	HITS-CLIP	23824327
MIRT679027	hsa-miR-3119	HITS-CLIP	23824327
MIRT679026	hsa-miR-3672	HITS-CLIP	23824327
MIRT679025	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT679024	hsa-miR-8055	HITS-CLIP	23824327
MIRT679023	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT662101	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT662100	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT662099	hsa-miR-4532	HITS-CLIP	23824327
MIRT662098	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT662097	hsa-miR-1281	HITS-CLIP	23824327
MIRT662096	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT662095	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT662094	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT662093	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT662092	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT662091	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT662090	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT662089	hsa-miR-4284	HITS-CLIP	23824327
MIRT662088	hsa-miR-4437	HITS-CLIP	23824327
MIRT1524242	hsa-miR-1202	CLIP-seq
MIRT1524243	hsa-miR-3194-5p	CLIP-seq
MIRT1524244	hsa-miR-3972	CLIP-seq
MIRT1524245	hsa-miR-4267	CLIP-seq
MIRT1524246	hsa-miR-4469	CLIP-seq
MIRT1524247	hsa-miR-1245b-5p	CLIP-seq
MIRT1524248	hsa-miR-181a	CLIP-seq
MIRT1524249	hsa-miR-181b	CLIP-seq
MIRT1524250	hsa-miR-181c	CLIP-seq
MIRT1524251	hsa-miR-181d	CLIP-seq
MIRT1524252	hsa-miR-1825	CLIP-seq
MIRT1524253	hsa-miR-186	CLIP-seq
MIRT1524254	hsa-miR-199a-5p	CLIP-seq
MIRT1524255	hsa-miR-199b-5p	CLIP-seq
MIRT1524256	hsa-miR-30a	CLIP-seq
MIRT1524257	hsa-miR-30b	CLIP-seq
MIRT1524258	hsa-miR-30c	CLIP-seq
MIRT1524259	hsa-miR-30d	CLIP-seq
MIRT1524260	hsa-miR-30e	CLIP-seq
MIRT1524261	hsa-miR-3120-3p	CLIP-seq
MIRT1524262	hsa-miR-3133	CLIP-seq
MIRT1524263	hsa-miR-3142	CLIP-seq
MIRT1524264	hsa-miR-3143	CLIP-seq
MIRT1524265	hsa-miR-3156-5p	CLIP-seq
MIRT1524266	hsa-miR-3174	CLIP-seq
MIRT1524267	hsa-miR-3609	CLIP-seq
MIRT1524268	hsa-miR-3925-3p	CLIP-seq
MIRT1524269	hsa-miR-4262	CLIP-seq
MIRT1524270	hsa-miR-4457	CLIP-seq
MIRT1524271	hsa-miR-4477a	CLIP-seq
MIRT1524272	hsa-miR-4753-5p	CLIP-seq
MIRT1524273	hsa-miR-4773	CLIP-seq
MIRT1524274	hsa-miR-513b	CLIP-seq
MIRT1524275	hsa-miR-515-5p	CLIP-seq
MIRT1524276	hsa-miR-543	CLIP-seq
MIRT1524277	hsa-miR-545	CLIP-seq
MIRT1524278	hsa-miR-548ah	CLIP-seq
MIRT1524279	hsa-miR-548p	CLIP-seq
MIRT1524280	hsa-miR-548t	CLIP-seq
MIRT1524281	hsa-miR-766	CLIP-seq
MIRT1524248	hsa-miR-181a	CLIP-seq
MIRT1524249	hsa-miR-181b	CLIP-seq
MIRT1524250	hsa-miR-181c	CLIP-seq
MIRT1524251	hsa-miR-181d	CLIP-seq
MIRT1524254	hsa-miR-199a-5p	CLIP-seq
MIRT1524255	hsa-miR-199b-5p	CLIP-seq
MIRT2377932	hsa-miR-23a	CLIP-seq
MIRT2377933	hsa-miR-23b	CLIP-seq
MIRT2377934	hsa-miR-23c	CLIP-seq
MIRT1524261	hsa-miR-3120-3p	CLIP-seq
MIRT1524264	hsa-miR-3143	CLIP-seq
MIRT1524265	hsa-miR-3156-5p	CLIP-seq
MIRT1524266	hsa-miR-3174	CLIP-seq
MIRT1524267	hsa-miR-3609	CLIP-seq
MIRT1524268	hsa-miR-3925-3p	CLIP-seq
MIRT1524269	hsa-miR-4262	CLIP-seq
MIRT1524270	hsa-miR-4457	CLIP-seq
MIRT2377935	hsa-miR-448	CLIP-seq
MIRT2377936	hsa-miR-4760-5p	CLIP-seq
MIRT1524273	hsa-miR-4773	CLIP-seq
MIRT1524274	hsa-miR-513b	CLIP-seq
MIRT1524276	hsa-miR-543	CLIP-seq
MIRT1524277	hsa-miR-545	CLIP-seq
MIRT1524278	hsa-miR-548ah	CLIP-seq
MIRT1524279	hsa-miR-548p	CLIP-seq
MIRT1524280	hsa-miR-548t	CLIP-seq
MIRT2696009	hsa-miR-191	CLIP-seq
MIRT2696010	hsa-miR-3167	CLIP-seq
MIRT2696011	hsa-miR-3689d	CLIP-seq
MIRT2696012	hsa-miR-3692	CLIP-seq
MIRT2696013	hsa-miR-4463	CLIP-seq
MIRT2696014	hsa-miR-4474-3p	CLIP-seq
MIRT2696015	hsa-miR-4724-3p	CLIP-seq
MIRT2696016	hsa-miR-587	CLIP-seq
MIRT2696017	hsa-miR-644	CLIP-seq
MIRT2696018	hsa-miR-876-5p	CLIP-seq

Gene ontology (GO) Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 32296183, 32814053
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0060255	Process	Regulation of macromolecule metabolic process	IEA
GO:0080090	Process	Regulation of primary metabolic process	IEA

Other IDs

• MIM: 617410
• HGNC: 20648
• e!Ensembl: ENSG00000105136

Protein

• UniProt ID: Q96HQ0
• Protein name: Zinc finger protein 419
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	203 → 225	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	343 → 365	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	399 → 421	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	259 → 281	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	371 → 393	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	315 → 337	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	455 → 477	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	427 → 449	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	483 → 505	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	287 → 309	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	231 → 253	Zinc finger, C2H2 type	Domain
  PF01352	KRAB	26 → 67	KRAB box	Family

• Sequence:

  MAAAALRDPAQVPVAADLLTDHEEGYVTFEDVAVYFSQEEWRLLDDAQRLLYRNVMLENF
  TLLASLGLASSKTHEITQLESWEEPFMPAWEVVTSAIPRGCWHGAEAEEAPEQIASVGLL
  SSNIQQHQKQHCGEKPLKRQEGRVPVLRSCKVHLSEKSLQSREVGKALLISSGVLKHQVT
  HTGEKSHRSSKSREAFHAGKRHYKCSECGKAFGQKYLLVQHQRLHAGKKTYECSECGKLF
  RDMSNLFIHQIVHTGERPYGCSNCGKSFSRNAHLIEHQRVHTGEKPFTCSECGKAFRHNS
  TLVQHHKIHTGVRPYECSECGKLFSFNSSLMKHQRIHTGERPYKCSECGKFYSHKSNLIK
  HWRVHTGERPYKCSDCGKFFTQCSSLMQHQKVHTGEKPFKCNECGRFFRENSTLVRHQRV
  HTGAKPYECRECGKFFSQSSTLMQHRKVHIGEKPFKCNECGRLFRENSSLVKHQRVHTGA
  KPYECRECGKFFRHNSSLFKHRRIHTGEMQ

• Sequence length: 510

Pathways

Reactome Pathway:

Generic Transcription Pathway

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Prostate cancer	Uncertain significance	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (7)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Carcinoma Ovarian Epithelial	Epithelial ovarian carcinoma	Pubtator	23551967	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	21738768	Associate	★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	21738768		★☆☆☆☆ Found in Text Mining only
Graft vs Host Disease	Graft-versus-host disease	Pubtator	21738768	Associate	★☆☆☆☆ Found in Text Mining only
Graft-vs-Host Disease	Graft-Vs-Host Disease	BEFREE	21738768		★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus, Systemic	Lupus Erythematosus	BEFREE	30635658		★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	21738768		★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for ZNF419.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZNF419.