ZNF410 (zinc finger protein 410)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 57862
• Gene name: Zinc finger protein 410
• Gene symbol: ZNF410
• Synonyms (NCBI Gene): APA-1, APA1
• Chromosome: 14
• Chromosome location: 14q24.3

miRNA Show/Hide all (192)

miRTarBase ID	miRNA	Experiments	Reference
MIRT022209	hsa-miR-124-3p	Microarray	18668037
MIRT191756	hsa-miR-129-5p	PAR-CLIP	21572407
MIRT191755	hsa-miR-32-3p	PAR-CLIP	21572407
MIRT552459	hsa-miR-512-5p	PAR-CLIP	21572407
MIRT552458	hsa-miR-510-5p	PAR-CLIP	21572407
MIRT280148	hsa-miR-5007-5p	PAR-CLIP	21572407
MIRT191762	hsa-miR-4690-3p	PAR-CLIP	21572407
MIRT191763	hsa-miR-5685	PAR-CLIP	21572407
MIRT191764	hsa-miR-5693	PAR-CLIP	21572407
MIRT552457	hsa-miR-550b-3p	PAR-CLIP	21572407
MIRT552456	hsa-miR-4640-5p	PAR-CLIP	21572407
MIRT552455	hsa-miR-4726-5p	PAR-CLIP	21572407
MIRT552454	hsa-miR-6508-3p	PAR-CLIP	21572407
MIRT191759	hsa-miR-3175	PAR-CLIP	21572407
MIRT191758	hsa-miR-1297	PAR-CLIP	21572407
MIRT191753	hsa-miR-26a-5p	PAR-CLIP	21572407
MIRT191754	hsa-miR-26b-5p	PAR-CLIP	21572407
MIRT191760	hsa-miR-4465	PAR-CLIP	21572407
MIRT191769	hsa-miR-7156-3p	PAR-CLIP	21572407
MIRT552453	hsa-miR-1301-3p	PAR-CLIP	21572407
MIRT552452	hsa-miR-5047	PAR-CLIP	21572407
MIRT552451	hsa-miR-6516-5p	PAR-CLIP	21572407
MIRT552450	hsa-miR-450b-5p	PAR-CLIP	21572407
MIRT552449	hsa-miR-507	PAR-CLIP	21572407
MIRT552448	hsa-miR-557	PAR-CLIP	21572407
MIRT552447	hsa-miR-3680-3p	PAR-CLIP	21572407
MIRT191756	hsa-miR-129-5p	PAR-CLIP	21572407
MIRT191755	hsa-miR-32-3p	PAR-CLIP	21572407
MIRT552459	hsa-miR-512-5p	PAR-CLIP	21572407
MIRT552458	hsa-miR-510-5p	PAR-CLIP	21572407
MIRT280148	hsa-miR-5007-5p	PAR-CLIP	21572407
MIRT191762	hsa-miR-4690-3p	PAR-CLIP	21572407
MIRT191763	hsa-miR-5685	PAR-CLIP	21572407
MIRT191764	hsa-miR-5693	PAR-CLIP	21572407
MIRT552457	hsa-miR-550b-3p	PAR-CLIP	21572407
MIRT552456	hsa-miR-4640-5p	PAR-CLIP	21572407
MIRT552455	hsa-miR-4726-5p	PAR-CLIP	21572407
MIRT552454	hsa-miR-6508-3p	PAR-CLIP	21572407
MIRT191759	hsa-miR-3175	PAR-CLIP	21572407
MIRT191758	hsa-miR-1297	PAR-CLIP	21572407
MIRT191753	hsa-miR-26a-5p	PAR-CLIP	21572407
MIRT191754	hsa-miR-26b-5p	PAR-CLIP	21572407
MIRT191760	hsa-miR-4465	PAR-CLIP	21572407
MIRT191769	hsa-miR-7156-3p	PAR-CLIP	21572407
MIRT552453	hsa-miR-1301-3p	PAR-CLIP	21572407
MIRT552452	hsa-miR-5047	PAR-CLIP	21572407
MIRT552451	hsa-miR-6516-5p	PAR-CLIP	21572407
MIRT552450	hsa-miR-450b-5p	PAR-CLIP	21572407
MIRT552449	hsa-miR-507	PAR-CLIP	21572407
MIRT552448	hsa-miR-557	PAR-CLIP	21572407
MIRT552447	hsa-miR-3680-3p	PAR-CLIP	21572407
MIRT1523951	hsa-let-7a	CLIP-seq
MIRT1523952	hsa-let-7b	CLIP-seq
MIRT1523953	hsa-let-7c	CLIP-seq
MIRT1523954	hsa-let-7d	CLIP-seq
MIRT1523955	hsa-let-7e	CLIP-seq
MIRT1523956	hsa-let-7f	CLIP-seq
MIRT1523957	hsa-let-7g	CLIP-seq
MIRT1523958	hsa-let-7i	CLIP-seq
MIRT1523959	hsa-miR-1183	CLIP-seq
MIRT1523960	hsa-miR-1197	CLIP-seq
MIRT1523961	hsa-miR-124	CLIP-seq
MIRT1523962	hsa-miR-1248	CLIP-seq
MIRT1523963	hsa-miR-1267	CLIP-seq
MIRT1523964	hsa-miR-127-5p	CLIP-seq
MIRT1523965	hsa-miR-1301	CLIP-seq
MIRT1523966	hsa-miR-133a	CLIP-seq
MIRT1523967	hsa-miR-133b	CLIP-seq
MIRT1523968	hsa-miR-1343	CLIP-seq
MIRT1523969	hsa-miR-26a	CLIP-seq
MIRT1523970	hsa-miR-26b	CLIP-seq
MIRT1523971	hsa-miR-297	CLIP-seq
MIRT1523972	hsa-miR-3143	CLIP-seq
MIRT1523973	hsa-miR-3609	CLIP-seq
MIRT1523974	hsa-miR-3714	CLIP-seq
MIRT1523975	hsa-miR-383	CLIP-seq
MIRT1523976	hsa-miR-3910	CLIP-seq
MIRT1523977	hsa-miR-3913-3p	CLIP-seq
MIRT1523978	hsa-miR-4265	CLIP-seq
MIRT1523979	hsa-miR-4287	CLIP-seq
MIRT1523980	hsa-miR-4296	CLIP-seq
MIRT1523981	hsa-miR-4299	CLIP-seq
MIRT1523982	hsa-miR-4322	CLIP-seq
MIRT1523983	hsa-miR-4417	CLIP-seq
MIRT1523984	hsa-miR-4458	CLIP-seq
MIRT1523985	hsa-miR-4500	CLIP-seq
MIRT1523986	hsa-miR-4635	CLIP-seq
MIRT1523987	hsa-miR-4652-3p	CLIP-seq
MIRT1523988	hsa-miR-4662a-3p	CLIP-seq
MIRT1523989	hsa-miR-4685-3p	CLIP-seq
MIRT1523990	hsa-miR-4690-5p	CLIP-seq
MIRT1523991	hsa-miR-4733-5p	CLIP-seq
MIRT1523992	hsa-miR-4747-5p	CLIP-seq
MIRT1523993	hsa-miR-4777-3p	CLIP-seq
MIRT1523994	hsa-miR-4778-3p	CLIP-seq
MIRT1523995	hsa-miR-4793-5p	CLIP-seq
MIRT1523996	hsa-miR-483-3p	CLIP-seq
MIRT1523997	hsa-miR-489	CLIP-seq
MIRT1523998	hsa-miR-499-3p	CLIP-seq
MIRT1523999	hsa-miR-499a-3p	CLIP-seq
MIRT1524000	hsa-miR-506	CLIP-seq
MIRT1524001	hsa-miR-520g	CLIP-seq
MIRT1524002	hsa-miR-520h	CLIP-seq
MIRT1524003	hsa-miR-548ah	CLIP-seq
MIRT1524004	hsa-miR-567	CLIP-seq
MIRT1524005	hsa-miR-570	CLIP-seq
MIRT1524006	hsa-miR-582-5p	CLIP-seq
MIRT1524007	hsa-miR-601	CLIP-seq
MIRT1524008	hsa-miR-642a	CLIP-seq
MIRT1524009	hsa-miR-661	CLIP-seq
MIRT1524010	hsa-miR-885-5p	CLIP-seq
MIRT1524011	hsa-miR-944	CLIP-seq
MIRT1524012	hsa-miR-98	CLIP-seq
MIRT1523965	hsa-miR-1301	CLIP-seq
MIRT1523969	hsa-miR-26a	CLIP-seq
MIRT1523970	hsa-miR-26b	CLIP-seq
MIRT1523951	hsa-let-7a	CLIP-seq
MIRT1523952	hsa-let-7b	CLIP-seq
MIRT1523953	hsa-let-7c	CLIP-seq
MIRT1523954	hsa-let-7d	CLIP-seq
MIRT1523955	hsa-let-7e	CLIP-seq
MIRT1523956	hsa-let-7f	CLIP-seq
MIRT1523957	hsa-let-7g	CLIP-seq
MIRT1523958	hsa-let-7i	CLIP-seq
MIRT2158383	hsa-miR-1298	CLIP-seq
MIRT1523966	hsa-miR-133a	CLIP-seq
MIRT1523967	hsa-miR-133b	CLIP-seq
MIRT1523969	hsa-miR-26a	CLIP-seq
MIRT1523970	hsa-miR-26b	CLIP-seq
MIRT1523976	hsa-miR-3910	CLIP-seq
MIRT2158384	hsa-miR-4317	CLIP-seq
MIRT1523984	hsa-miR-4458	CLIP-seq
MIRT1523985	hsa-miR-4500	CLIP-seq
MIRT1523986	hsa-miR-4635	CLIP-seq
MIRT1523988	hsa-miR-4662a-3p	CLIP-seq
MIRT1523991	hsa-miR-4733-5p	CLIP-seq
MIRT1523992	hsa-miR-4747-5p	CLIP-seq
MIRT1523993	hsa-miR-4777-3p	CLIP-seq
MIRT1524005	hsa-miR-570	CLIP-seq
MIRT1524006	hsa-miR-582-5p	CLIP-seq
MIRT1524007	hsa-miR-601	CLIP-seq
MIRT2158385	hsa-miR-616	CLIP-seq
MIRT1524009	hsa-miR-661	CLIP-seq
MIRT1524011	hsa-miR-944	CLIP-seq
MIRT1524012	hsa-miR-98	CLIP-seq
MIRT1523962	hsa-miR-1248	CLIP-seq
MIRT1523963	hsa-miR-1267	CLIP-seq
MIRT1523964	hsa-miR-127-5p	CLIP-seq
MIRT1523968	hsa-miR-1343	CLIP-seq
MIRT2670226	hsa-miR-330-3p	CLIP-seq
MIRT2670227	hsa-miR-3607-5p	CLIP-seq
MIRT1523976	hsa-miR-3910	CLIP-seq
MIRT1523977	hsa-miR-3913-3p	CLIP-seq
MIRT1523979	hsa-miR-4287	CLIP-seq
MIRT1523981	hsa-miR-4299	CLIP-seq
MIRT1523986	hsa-miR-4635	CLIP-seq
MIRT1523989	hsa-miR-4685-3p	CLIP-seq
MIRT1523990	hsa-miR-4690-5p	CLIP-seq
MIRT2670228	hsa-miR-4716-5p	CLIP-seq
MIRT1523994	hsa-miR-4778-3p	CLIP-seq
MIRT1523996	hsa-miR-483-3p	CLIP-seq
MIRT1523997	hsa-miR-489	CLIP-seq
MIRT1523998	hsa-miR-499-3p	CLIP-seq
MIRT1523999	hsa-miR-499a-3p	CLIP-seq
MIRT1524005	hsa-miR-570	CLIP-seq
MIRT1524011	hsa-miR-944	CLIP-seq
MIRT1523962	hsa-miR-1248	CLIP-seq
MIRT1523963	hsa-miR-1267	CLIP-seq
MIRT1523964	hsa-miR-127-5p	CLIP-seq
MIRT1523968	hsa-miR-1343	CLIP-seq
MIRT2696000	hsa-miR-3192	CLIP-seq
MIRT2670226	hsa-miR-330-3p	CLIP-seq
MIRT2670227	hsa-miR-3607-5p	CLIP-seq
MIRT1523976	hsa-miR-3910	CLIP-seq
MIRT1523977	hsa-miR-3913-3p	CLIP-seq
MIRT1523979	hsa-miR-4287	CLIP-seq
MIRT1523981	hsa-miR-4299	CLIP-seq
MIRT2696001	hsa-miR-4314	CLIP-seq
MIRT1523986	hsa-miR-4635	CLIP-seq
MIRT2696002	hsa-miR-4646-5p	CLIP-seq
MIRT1523989	hsa-miR-4685-3p	CLIP-seq
MIRT1523990	hsa-miR-4690-5p	CLIP-seq
MIRT2670228	hsa-miR-4716-5p	CLIP-seq
MIRT1523994	hsa-miR-4778-3p	CLIP-seq
MIRT1523996	hsa-miR-483-3p	CLIP-seq
MIRT1523997	hsa-miR-489	CLIP-seq
MIRT1523998	hsa-miR-499-3p	CLIP-seq
MIRT1523999	hsa-miR-499a-3p	CLIP-seq
MIRT1524005	hsa-miR-570	CLIP-seq
MIRT2696003	hsa-miR-627	CLIP-seq
MIRT2696004	hsa-miR-924	CLIP-seq
MIRT1524011	hsa-miR-944	CLIP-seq

Gene ontology (GO) Show/Hide all (22)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IMP	33301730
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IDA	33859416
GO:0003712	Function	Transcription coregulator activity	IBA
GO:0005515	Function	Protein binding	IPI	20211142, 25416956, 27107012, 32296183, 32814053
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005694	Component	Chromosome	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0010558	Process	Negative regulation of macromolecule biosynthetic process	IEA
GO:0010629	Process	Negative regulation of gene expression	IDA	33859416
GO:0010629	Process	Negative regulation of gene expression	IMP	33301730
GO:0015671	Process	Oxygen transport	IDA	19065339, 22096240
GO:0043565	Function	Sequence-specific DNA binding	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	33859416
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IMP	33301730
GO:0046872	Function	Metal ion binding	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IMP	33301730

Other IDs

• MIM: 619427
• HGNC: 20144
• e!Ensembl: ENSG00000119725

Protein

• UniProt ID: Q86VK4
• Protein name: Zinc finger protein 410 (Another partner for ARF 1)
• Protein function: Transcription factor that binds to the sequence motif 5'-CATCCCATAATA-3', and is specifically required to silence expression of fetal hemoglobin in adult erythroid cells (PubMed:33301730, PubMed:33859416). Prevents expression of fetal hemoglobin
• PDB: 6WMI
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	279 → 303	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	339 → 362	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	249 → 273	Zinc finger, C2H2 type	Domain

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:12370286}.
• Sequence:

  MLSDELESKPELLVQFVQNTSIPLGQGLVESEAKDITCLSLLPVTEASECSRLMLPDDTT
  NHSNSSKEVPSSAVLRSLRVNVGPDGEETRAQTVQKSPEFLSTSESSSLLQDLQPSDSTS
  FILLNLTRAGLGSSAEHLVFVQDEAEDSGNDFLSSESTDSSIPWFLRVQELAHDSLIAAT
  RAQLAKNAKTSSNGENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVWPAHFKYHL
  KTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHR
  RIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRK
  HHLQLGAAGSQEQEQTAEPLMGSSLLEEASVPSKNLVSMNSQPSLGGESLNLPNTNSILG
  VDDEVLAEGSPRSLSSVPDVTHHLVTMQSGRQSYEVSVLTAVNPQELLNQGDLTERRT

• Sequence length: 478

Related Genes

No strongly related genes found yet for ZNF410.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZNF410.