ZNF26 (zinc finger protein 26)

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Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases Diseases linked via similar genes

Gene

• Entrez ID: 7574
• Gene name: Zinc finger protein 26
• Gene symbol: ZNF26
• Synonyms (NCBI Gene): HEL-179, KOX20
• Chromosome: 12
• Chromosome location: 12q24.33

miRNA Show/Hide all (64)

miRTarBase ID	miRNA	Experiments	Reference
MIRT1519749	hsa-miR-1178	CLIP-seq
MIRT1519750	hsa-miR-1206	CLIP-seq
MIRT1519751	hsa-miR-1260	CLIP-seq
MIRT1519752	hsa-miR-1260b	CLIP-seq
MIRT1519753	hsa-miR-1296	CLIP-seq
MIRT1519754	hsa-miR-137	CLIP-seq
MIRT1519755	hsa-miR-188-3p	CLIP-seq
MIRT1519756	hsa-miR-1976	CLIP-seq
MIRT1519757	hsa-miR-202	CLIP-seq
MIRT1519758	hsa-miR-2909	CLIP-seq
MIRT1519759	hsa-miR-3137	CLIP-seq
MIRT1519760	hsa-miR-3156-3p	CLIP-seq
MIRT1519761	hsa-miR-3622a-3p	CLIP-seq
MIRT1519762	hsa-miR-3622b-3p	CLIP-seq
MIRT1519763	hsa-miR-3646	CLIP-seq
MIRT1519764	hsa-miR-3659	CLIP-seq
MIRT1519765	hsa-miR-3662	CLIP-seq
MIRT1519766	hsa-miR-3667-3p	CLIP-seq
MIRT1519767	hsa-miR-3681	CLIP-seq
MIRT1519768	hsa-miR-370	CLIP-seq
MIRT1519769	hsa-miR-3919	CLIP-seq
MIRT1519770	hsa-miR-3925-3p	CLIP-seq
MIRT1519771	hsa-miR-4506	CLIP-seq
MIRT1519772	hsa-miR-4512	CLIP-seq
MIRT1519773	hsa-miR-4658	CLIP-seq
MIRT1519774	hsa-miR-4678	CLIP-seq
MIRT1519775	hsa-miR-4766-5p	CLIP-seq
MIRT1519776	hsa-miR-4775	CLIP-seq
MIRT1519777	hsa-miR-515-5p	CLIP-seq
MIRT1519778	hsa-miR-520a-5p	CLIP-seq
MIRT1519779	hsa-miR-525-5p	CLIP-seq
MIRT1519780	hsa-miR-555	CLIP-seq
MIRT1519781	hsa-miR-570	CLIP-seq
MIRT1519782	hsa-miR-574-5p	CLIP-seq
MIRT1519783	hsa-miR-590-3p	CLIP-seq
MIRT1519784	hsa-miR-766	CLIP-seq
MIRT1519785	hsa-miR-885-5p	CLIP-seq
MIRT2376493	hsa-miR-140-3p	CLIP-seq
MIRT2376494	hsa-miR-224	CLIP-seq
MIRT2376495	hsa-miR-23a	CLIP-seq
MIRT2376496	hsa-miR-23b	CLIP-seq
MIRT2376497	hsa-miR-23c	CLIP-seq
MIRT2376498	hsa-miR-3117-5p	CLIP-seq
MIRT2376499	hsa-miR-3183	CLIP-seq
MIRT2376500	hsa-miR-3664-3p	CLIP-seq
MIRT1519769	hsa-miR-3919	CLIP-seq
MIRT2376501	hsa-miR-4279	CLIP-seq
MIRT2376502	hsa-miR-4723-3p	CLIP-seq
MIRT1519775	hsa-miR-4766-5p	CLIP-seq
MIRT2376503	hsa-miR-510	CLIP-seq
MIRT2376504	hsa-miR-584	CLIP-seq
MIRT2376505	hsa-miR-873	CLIP-seq
MIRT1519772	hsa-miR-4512	CLIP-seq
MIRT2376499	hsa-miR-3183	CLIP-seq
MIRT1519764	hsa-miR-3659	CLIP-seq
MIRT2695852	hsa-miR-3920	CLIP-seq
MIRT2695853	hsa-miR-3921	CLIP-seq
MIRT2695854	hsa-miR-4653-5p	CLIP-seq
MIRT1519773	hsa-miR-4658	CLIP-seq
MIRT2376502	hsa-miR-4723-3p	CLIP-seq
MIRT2695855	hsa-miR-489	CLIP-seq
MIRT2695856	hsa-miR-514	CLIP-seq
MIRT2695857	hsa-miR-514b-3p	CLIP-seq
MIRT1519782	hsa-miR-574-5p	CLIP-seq

Gene ontology (GO) Show/Hide all (6)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 31515488
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 194537
• HGNC: 13053
• e!Ensembl: ENSG00000198393

Protein

• UniProt ID: P17031
• Protein name: Zinc finger protein 26 (Zinc finger protein KOX20)
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	482 → 504	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	314 → 336	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	202 → 224	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	370 → 392	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	398 → 420	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	454 → 476	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	342 → 364	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	286 → 308	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	230 → 252	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	426 → 448	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	174 → 196	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	510 → 532	Zinc finger, C2H2 type	Domain
  PF01352	KRAB	13 → 54	KRAB box	Family

• Sequence:

  MATSFRTASCWGLLSFKDISMEFTWDEWQLLDSTQKYLYRDVILENYHNLISVGYHGTKP
  DLIFKLEQGEDPWIINAKISRQSCPDGWEEWYQNNQDELESIERSYACSVLGRLNLSKTH
  DSSRQRLYNTRGKSLTQNSAPSRSYLRKNPDKFHGYEEPYFLKHQRAHSIEKNCVCSECG
  KAFRCKSQLIVHLRIHTGERPYECSKCERAFSAKSNLNAHQRVHTGEKPYSCSECEKVFS
  FRSQLIVHQEIHTGGKPYGCSECGKAYSWKSQLLLHQRSHTGVKPYECSECGKAFSLKSP
  FVVHQRTHTGVKPHKCSECGKAFRSKSYLLVHIRMHTGEKPYQCSDCGKAFNMKTQLIVH
  QGVHTGNNPYQCGECGKAFGRKEQLTAHLRAHAGEKPYGCSECGKAFSSKSYLVIHRRTH
  TGERPYECSLCERAFCGKSQLIIHQRTHSTEKPYECNECEKAYPRKASLQIHQKTHSGEK
  PFKCSECGKAFTQKSSLSEHQRVHTGEKPWKCSECGKSFCWNSGLRIHRKTHK

• Sequence length: 533

Pathways

Reactome Pathway:

Generic Transcription Pathway

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
EBV-positive nodal T- and NK-cell lymphoma	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Related Genes

No strongly related genes found yet for ZNF26.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZNF26.