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Gene Gene information from NCBI Gene database.
Entrez ID 56242
Gene name Zinc finger protein 253
Gene symbol ZNF253
Synonyms (NCBI Gene)
BMZF-1BMZF1ZNF411
Chromosome 19
Chromosome location 19p13.11
miRNA miRNA information provided by mirtarbase database.
427 Show/Hide all (427)
miRTarBase ID miRNA Experiments Reference
MIRT683299 hsa-miR-181a-5p HITS-CLIP 23313552
MIRT683298 hsa-miR-181b-5p HITS-CLIP 23313552
MIRT683297 hsa-miR-181c-5p HITS-CLIP 23313552
MIRT683296 hsa-miR-181d-5p HITS-CLIP 23313552
MIRT683295 hsa-miR-4262 HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
10 Show/Hide all (10)
GO ID Ontology Definition Evidence Reference
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0003677 Function DNA binding IEA
GO:0005634 Component Nucleus IEA
GO:0006355 Process Regulation of DNA-templated transcription IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
606954 13497 ENSG00000256771
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O75346
Protein name Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1) (Zinc finger protein 411)
Protein function May function as a transcription factor. Seem to have a transcriptional repression activity.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00096 zf-C2H2 228 → 250 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 424 → 446 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 200 → 222 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 312 → 334 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 256 → 278 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 284 → 306 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 172 → 194 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 452 → 474 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 368 → 390 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 396 → 418 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 340 → 362 Zinc finger, C2H2 type Domain
PF01352 KRAB 3 → 44 KRAB box Family
Tissue specificity TISSUE SPECIFICITY: Expressed in bone marrow and in monocytic and immature erythroid cell lines.
Sequence
MGPLQFRDVAIEFSLEEWHCLDTAQRNLYRDVMLENYRNLVFLGIVVSKPDLVTCLEQGK
KPLTMERHEMIAKPPVMSSHFAQDLWPENIQNSFQIGMLRRYEECRHDNLQLKKGCKSVG
EHKVHKGGYNGLNQCLTTTQKEIFQCDKYGKVFHKFSNSNTYKTRHTGINLFKCIICGKA
FKRSSTLTTHKKIH
TGEKPYRCEECGKAFNQSANLTTHKRIHTGEKPYRCEECGKAFKQS
SNLTTHKKIH
TGEKPYKCEECGKAFNRSTDLTTHKIVHTGEKPYKCEECGKAFKHPSHVT
THKKIH
TRGKPYNCEECGKSFKHCSNLTIHKRIHTGEKPYKCEECGKAFHLSSHLTTHKI
LH
TGEKPYRCRECGKAFNHSTTLFSHEKIHTGEKPYKCDECGKTFTWPSILSKHKRTHTG
EKPYKCEECGKSFTASSTLTTHKRIHTGEKPYKCEECGKAFNWSSDLNKHKKIHIERKPY
IVKNVTDLLNVPPLLISIR
Sequence length 499
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Generic Transcription Pathway