ZNF212 (zinc finger protein 212)

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Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 7988
• Gene name: Zinc finger protein 212
• Gene symbol: ZNF212
• Synonyms (NCBI Gene): C2H2-150, ZNF182, ZNFC150
• Chromosome: 7
• Chromosome location: 7q36.1
• Summary: This gene belongs to the C2H2-type zinc finger gene family. The zinc finger proteins are involved in gene regulation and development, and are quite conserved throughout evolution. Like this gene product, a third of the zinc finger proteins containing C2H2

miRNA Show/Hide all (117)

miRTarBase ID	miRNA	Experiments	Reference
MIRT045981	hsa-miR-125b-5p	CLASH	23622248
MIRT037645	hsa-miR-744-5p	CLASH	23622248
MIRT723192	hsa-miR-6729-3p	HITS-CLIP	19536157
MIRT723191	hsa-miR-361-3p	HITS-CLIP	19536157
MIRT723190	hsa-miR-6887-3p	HITS-CLIP	19536157
MIRT723189	hsa-miR-4715-3p	HITS-CLIP	19536157
MIRT457923	hsa-miR-6858-3p	PAR-CLIP	23592263
MIRT457922	hsa-miR-4676-5p	PAR-CLIP	23592263
MIRT457921	hsa-miR-575	PAR-CLIP	23592263
MIRT457920	hsa-miR-4459	PAR-CLIP	23592263
MIRT457919	hsa-miR-103b	PAR-CLIP	23592263
MIRT457918	hsa-miR-665	PAR-CLIP	23592263
MIRT457917	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT457916	hsa-miR-4784	PAR-CLIP	23592263
MIRT457915	hsa-miR-1914-3p	PAR-CLIP	23592263
MIRT457914	hsa-miR-5194	PAR-CLIP	23592263
MIRT457913	hsa-miR-6738-5p	PAR-CLIP	23592263
MIRT457912	hsa-miR-6134	PAR-CLIP	23592263
MIRT457911	hsa-miR-6077	PAR-CLIP	23592263
MIRT457910	hsa-miR-765	PAR-CLIP	23592263
MIRT457909	hsa-miR-3689d	PAR-CLIP	23592263
MIRT457908	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT457907	hsa-miR-4747-5p	PAR-CLIP	23592263
MIRT457906	hsa-miR-5196-5p	PAR-CLIP	23592263
MIRT457905	hsa-miR-4646-5p	PAR-CLIP	23592263
MIRT723192	hsa-miR-6729-3p	HITS-CLIP	19536157
MIRT723191	hsa-miR-361-3p	HITS-CLIP	19536157
MIRT723190	hsa-miR-6887-3p	HITS-CLIP	19536157
MIRT723189	hsa-miR-4715-3p	HITS-CLIP	19536157
MIRT457923	hsa-miR-6858-3p	PAR-CLIP	23592263
MIRT457922	hsa-miR-4676-5p	PAR-CLIP	23592263
MIRT457921	hsa-miR-575	PAR-CLIP	23592263
MIRT457920	hsa-miR-4459	PAR-CLIP	23592263
MIRT457919	hsa-miR-103b	PAR-CLIP	23592263
MIRT457918	hsa-miR-665	PAR-CLIP	23592263
MIRT457917	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT457916	hsa-miR-4784	PAR-CLIP	23592263
MIRT457915	hsa-miR-1914-3p	PAR-CLIP	23592263
MIRT457914	hsa-miR-5194	PAR-CLIP	23592263
MIRT457913	hsa-miR-6738-5p	PAR-CLIP	23592263
MIRT457912	hsa-miR-6134	PAR-CLIP	23592263
MIRT457911	hsa-miR-6077	PAR-CLIP	23592263
MIRT457910	hsa-miR-765	PAR-CLIP	23592263
MIRT457909	hsa-miR-3689d	PAR-CLIP	23592263
MIRT457908	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT457907	hsa-miR-4747-5p	PAR-CLIP	23592263
MIRT457906	hsa-miR-5196-5p	PAR-CLIP	23592263
MIRT457905	hsa-miR-4646-5p	PAR-CLIP	23592263
MIRT1518082	hsa-miR-1297	CLIP-seq
MIRT1518083	hsa-miR-133a	CLIP-seq
MIRT1518084	hsa-miR-133b	CLIP-seq
MIRT1518085	hsa-miR-18a	CLIP-seq
MIRT1518086	hsa-miR-18b	CLIP-seq
MIRT1518087	hsa-miR-2054	CLIP-seq
MIRT1518088	hsa-miR-2278	CLIP-seq
MIRT1518089	hsa-miR-26a	CLIP-seq
MIRT1518090	hsa-miR-26b	CLIP-seq
MIRT1518091	hsa-miR-3120-3p	CLIP-seq
MIRT1518092	hsa-miR-331-3p	CLIP-seq
MIRT1518093	hsa-miR-3613-3p	CLIP-seq
MIRT1518094	hsa-miR-3657	CLIP-seq
MIRT1518095	hsa-miR-3671	CLIP-seq
MIRT1518096	hsa-miR-3672	CLIP-seq
MIRT1518097	hsa-miR-3914	CLIP-seq
MIRT1518098	hsa-miR-4465	CLIP-seq
MIRT1518099	hsa-miR-4480	CLIP-seq
MIRT1518100	hsa-miR-4729	CLIP-seq
MIRT1518101	hsa-miR-4735-3p	CLIP-seq
MIRT1518102	hsa-miR-4735-5p	CLIP-seq
MIRT1518103	hsa-miR-493	CLIP-seq
MIRT1518104	hsa-miR-495	CLIP-seq
MIRT1518105	hsa-miR-509-3p	CLIP-seq
MIRT1518106	hsa-miR-545	CLIP-seq
MIRT1518107	hsa-miR-579	CLIP-seq
MIRT1518108	hsa-miR-888	CLIP-seq
MIRT2156383	hsa-miR-125a-5p	CLIP-seq
MIRT2156384	hsa-miR-125b	CLIP-seq
MIRT2156385	hsa-miR-1910	CLIP-seq
MIRT2156386	hsa-miR-2114	CLIP-seq
MIRT2156387	hsa-miR-4264	CLIP-seq
MIRT2156388	hsa-miR-4319	CLIP-seq
MIRT2156389	hsa-miR-4511	CLIP-seq
MIRT2156390	hsa-miR-455-3p	CLIP-seq
MIRT2156391	hsa-miR-4732-3p	CLIP-seq
MIRT2156392	hsa-miR-483-3p	CLIP-seq
MIRT2156393	hsa-miR-670	CLIP-seq
MIRT2156394	hsa-miR-944	CLIP-seq
MIRT2375964	hsa-miR-214	CLIP-seq
MIRT1518088	hsa-miR-2278	CLIP-seq
MIRT1518092	hsa-miR-331-3p	CLIP-seq
MIRT2375965	hsa-miR-3619-5p	CLIP-seq
MIRT1518094	hsa-miR-3657	CLIP-seq
MIRT1518100	hsa-miR-4729	CLIP-seq
MIRT1518104	hsa-miR-495	CLIP-seq
MIRT1518107	hsa-miR-579	CLIP-seq
MIRT2375966	hsa-miR-761	CLIP-seq
MIRT2375967	hsa-miR-885-3p	CLIP-seq
MIRT2668431	hsa-miR-1244	CLIP-seq
MIRT2668432	hsa-miR-218	CLIP-seq
MIRT2668433	hsa-miR-3140-3p	CLIP-seq
MIRT2668434	hsa-miR-3192	CLIP-seq
MIRT2668435	hsa-miR-326	CLIP-seq
MIRT2668436	hsa-miR-330-5p	CLIP-seq
MIRT2668437	hsa-miR-3664-5p	CLIP-seq
MIRT2668438	hsa-miR-3689a-3p	CLIP-seq
MIRT2668439	hsa-miR-3689c	CLIP-seq
MIRT2668440	hsa-miR-3973	CLIP-seq
MIRT2668441	hsa-miR-4314	CLIP-seq
MIRT2668442	hsa-miR-4714-5p	CLIP-seq
MIRT2668443	hsa-miR-4728-5p	CLIP-seq
MIRT2668444	hsa-miR-4761-5p	CLIP-seq
MIRT1518104	hsa-miR-495	CLIP-seq
MIRT2668445	hsa-miR-624	CLIP-seq
MIRT2668446	hsa-miR-636	CLIP-seq
MIRT2668447	hsa-miR-802	CLIP-seq
MIRT2668435	hsa-miR-326	CLIP-seq
MIRT2668436	hsa-miR-330-5p	CLIP-seq

Gene ontology (GO) Show/Hide all (21)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IEA
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IBA
GO:0005515	Function	Protein binding	IPI	18255255, 23455924, 25416956, 31515488, 32296183
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	NAS	7633419
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0008270	Function	Zinc ion binding	NAS	7633419
GO:0016358	Process	Dendrite development	IEA
GO:0042802	Function	Identical protein binding	IPI	18255255
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0050885	Process	Neuromuscular process controlling balance	IEA
GO:0051402	Process	Neuron apoptotic process	IEA
GO:0051867	Process	General adaptation syndrome, behavioral process	IEA
GO:0090659	Process	Walking behavior	IEA
GO:0097305	Process	Response to alcohol	IEA

Other IDs

• MIM: 602386
• HGNC: 13004
• e!Ensembl: ENSG00000170260

Protein

• UniProt ID: Q9UDV6
• Protein name: Zinc finger protein 212 (Zinc finger protein C2H2-150)
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	427 → 449	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	455 → 477	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	316 → 338	Zinc finger, C2H2 type	Domain
  PF01352	KRAB	142 → 180	KRAB box	Family
  PF12417	DUF3669	41 → 111	Zinc finger protein	Family
  PF13912	zf-C2H2_6	368 → 394		Domain

• Sequence:

  MAESAPARHRRKRRSTPLTSSTLPSQATEKSSYFQTTEISLWTVVAAIQAVEKKMESQAA
  RLQSLEGRTGTAEKKLADCEKMAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRN
  RNFWILRLPPGSKGEAPKVSRSLENDGVCFTEQEWENLEDWQKELYRNVMESNYETLVSL
  KVLGQTEGEAELGTEMLGDLEEEGPGGAHPAGGVMIKQELQYTQEGPADLPGEFSCIAEE
  QAFLSPEQTELWGGQGSSVLLETGPGDSTLEEPVGSRVPSSSRTVGCPKQKSHRQVQLDQ
  ECGQGLKLKKDTSRPYECSECEITFRYKQQLATHLRSHSGWGSCTPEEPEESLRPRPRLK
  PQTKKAKLHQCDVCLRSFSCKVSLVTHQRCHLQEGPSAGQHVQERFSPNSLVALPGHIPW
  RKSRSSLICGYCGKSFSHPSDLVRHQRIHTGERPYSCTECEKSFVQKQHLLQHQKIHQRE
  RGGLALEPGRPNGLL

• Sequence length: 495

Pathways

Reactome Pathway:

Generic Transcription Pathway

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Lung cancer	Uncertain significance	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Developmental Disabilities	Developmental disability	Pubtator	30559312	Associate	★☆☆☆☆ Found in Text Mining only
Wiskott-Aldrich Syndrome	Wiskott-Aldrich Syndrome	BEFREE	8530079		★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for ZNF212.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZNF212.