ZNF197 (zinc finger protein 197)

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Gene miRNA Gene ontology Other IDs Protein Pathways Diseases linked via similar genes

Gene

• Entrez ID: 10168
• Gene name: Zinc finger protein 197
• Gene symbol: ZNF197
• Synonyms (NCBI Gene): D3S1363E, P18, VHLaK, ZKSCAN9, ZNF166, ZNF20, ZSCAN41
• Chromosome: 3
• Chromosome location: 3p21.31
• Summary: This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associ

miRNA Show/Hide all (145)

miRTarBase ID	miRNA	Experiments	Reference
MIRT735839	hsa-miR-4780	Microarray, in vitro cullelar assays, qRT-PCR, Immunocytochemistry (ICC)	32765063
MIRT1517607	hsa-miR-183	CLIP-seq
MIRT1517608	hsa-miR-219-1-3p	CLIP-seq
MIRT1517609	hsa-miR-3074-3p	CLIP-seq
MIRT1517610	hsa-miR-3140-3p	CLIP-seq
MIRT1517611	hsa-miR-3200-5p	CLIP-seq
MIRT1517612	hsa-miR-3614-3p	CLIP-seq
MIRT1517613	hsa-miR-361-5p	CLIP-seq
MIRT1517614	hsa-miR-3647-3p	CLIP-seq
MIRT1517615	hsa-miR-3938	CLIP-seq
MIRT1517616	hsa-miR-4303	CLIP-seq
MIRT1517617	hsa-miR-4775	CLIP-seq
MIRT1517618	hsa-miR-485-3p	CLIP-seq
MIRT1517619	hsa-miR-488	CLIP-seq
MIRT1517620	hsa-miR-548l	CLIP-seq
MIRT1517621	hsa-miR-590-3p	CLIP-seq
MIRT1517622	hsa-miR-627	CLIP-seq
MIRT1517623	hsa-miR-759	CLIP-seq
MIRT1517624	hsa-let-7a	CLIP-seq
MIRT1517625	hsa-let-7b	CLIP-seq
MIRT1517626	hsa-let-7c	CLIP-seq
MIRT1517627	hsa-let-7d	CLIP-seq
MIRT1517628	hsa-let-7e	CLIP-seq
MIRT1517629	hsa-let-7f	CLIP-seq
MIRT1517630	hsa-let-7g	CLIP-seq
MIRT1517631	hsa-let-7i	CLIP-seq
MIRT1517632	hsa-miR-106a	CLIP-seq
MIRT1517633	hsa-miR-106b	CLIP-seq
MIRT1517634	hsa-miR-10a	CLIP-seq
MIRT1517635	hsa-miR-10b	CLIP-seq
MIRT1517636	hsa-miR-1228	CLIP-seq
MIRT1517637	hsa-miR-1234	CLIP-seq
MIRT1517638	hsa-miR-1294	CLIP-seq
MIRT1517639	hsa-miR-1299	CLIP-seq
MIRT1517640	hsa-miR-1303	CLIP-seq
MIRT1517641	hsa-miR-17	CLIP-seq
MIRT1517642	hsa-miR-1825	CLIP-seq
MIRT1517643	hsa-miR-199a-5p	CLIP-seq
MIRT1517644	hsa-miR-199b-5p	CLIP-seq
MIRT1517645	hsa-miR-202	CLIP-seq
MIRT1517646	hsa-miR-20a	CLIP-seq
MIRT1517647	hsa-miR-20b	CLIP-seq
MIRT1517648	hsa-miR-214	CLIP-seq
MIRT1517649	hsa-miR-2355-3p	CLIP-seq
MIRT1517650	hsa-miR-2681	CLIP-seq
MIRT1517651	hsa-miR-302a	CLIP-seq
MIRT1517652	hsa-miR-302b	CLIP-seq
MIRT1517653	hsa-miR-302c	CLIP-seq
MIRT1517654	hsa-miR-302d	CLIP-seq
MIRT1517655	hsa-miR-302e	CLIP-seq
MIRT1517656	hsa-miR-3153	CLIP-seq
MIRT1517657	hsa-miR-3182	CLIP-seq
MIRT1517658	hsa-miR-3187-3p	CLIP-seq
MIRT1517659	hsa-miR-323b-5p	CLIP-seq
MIRT1517660	hsa-miR-331-5p	CLIP-seq
MIRT1517661	hsa-miR-3619-5p	CLIP-seq
MIRT1517662	hsa-miR-3622a-3p	CLIP-seq
MIRT1517663	hsa-miR-3622b-3p	CLIP-seq
MIRT1517664	hsa-miR-3655	CLIP-seq
MIRT1517665	hsa-miR-371-5p	CLIP-seq
MIRT1517666	hsa-miR-371b-5p	CLIP-seq
MIRT1517667	hsa-miR-372	CLIP-seq
MIRT1517668	hsa-miR-373	CLIP-seq
MIRT1517669	hsa-miR-3909	CLIP-seq
MIRT1517670	hsa-miR-3920	CLIP-seq
MIRT1517671	hsa-miR-3929	CLIP-seq
MIRT1517672	hsa-miR-3973	CLIP-seq
MIRT1517673	hsa-miR-4291	CLIP-seq
MIRT1517674	hsa-miR-4316	CLIP-seq
MIRT1517675	hsa-miR-4419b	CLIP-seq
MIRT1517676	hsa-miR-4438	CLIP-seq
MIRT1517677	hsa-miR-4458	CLIP-seq
MIRT1517678	hsa-miR-4475	CLIP-seq
MIRT1517679	hsa-miR-4478	CLIP-seq
MIRT1517680	hsa-miR-4500	CLIP-seq
MIRT1517681	hsa-miR-4529-5p	CLIP-seq
MIRT1517682	hsa-miR-4665-3p	CLIP-seq
MIRT1517683	hsa-miR-4677-3p	CLIP-seq
MIRT1517684	hsa-miR-4678	CLIP-seq
MIRT1517685	hsa-miR-4717-3p	CLIP-seq
MIRT1517686	hsa-miR-4731-5p	CLIP-seq
MIRT1517687	hsa-miR-4757-5p	CLIP-seq
MIRT1517688	hsa-miR-4762-3p	CLIP-seq
MIRT1517689	hsa-miR-4771	CLIP-seq
MIRT1517690	hsa-miR-4782-5p	CLIP-seq
MIRT1517691	hsa-miR-485-5p	CLIP-seq
MIRT1517692	hsa-miR-499-3p	CLIP-seq
MIRT1517693	hsa-miR-499a-3p	CLIP-seq
MIRT1517694	hsa-miR-5095	CLIP-seq
MIRT1517695	hsa-miR-512-3p	CLIP-seq
MIRT1517696	hsa-miR-516b	CLIP-seq
MIRT1517697	hsa-miR-519d	CLIP-seq
MIRT1517698	hsa-miR-520a-3p	CLIP-seq
MIRT1517699	hsa-miR-520b	CLIP-seq
MIRT1517700	hsa-miR-520c-3p	CLIP-seq
MIRT1517701	hsa-miR-520d-3p	CLIP-seq
MIRT1517702	hsa-miR-520e	CLIP-seq
MIRT1517703	hsa-miR-520g	CLIP-seq
MIRT1517704	hsa-miR-520h	CLIP-seq
MIRT1517705	hsa-miR-676	CLIP-seq
MIRT1517706	hsa-miR-761	CLIP-seq
MIRT1517707	hsa-miR-877	CLIP-seq
MIRT1517708	hsa-miR-922	CLIP-seq
MIRT1517709	hsa-miR-93	CLIP-seq
MIRT1517710	hsa-miR-98	CLIP-seq
MIRT2156289	hsa-miR-1284	CLIP-seq
MIRT2156290	hsa-miR-4276	CLIP-seq
MIRT2375841	hsa-miR-122	CLIP-seq
MIRT2375842	hsa-miR-130a	CLIP-seq
MIRT2375843	hsa-miR-130b	CLIP-seq
MIRT2375844	hsa-miR-301a	CLIP-seq
MIRT2375845	hsa-miR-301b	CLIP-seq
MIRT2375846	hsa-miR-3135b	CLIP-seq
MIRT2375847	hsa-miR-3652	CLIP-seq
MIRT2375848	hsa-miR-3666	CLIP-seq
MIRT2375849	hsa-miR-4295	CLIP-seq
MIRT2375850	hsa-miR-4423-5p	CLIP-seq
MIRT2375851	hsa-miR-4430	CLIP-seq
MIRT2375852	hsa-miR-454	CLIP-seq
MIRT2375853	hsa-miR-549	CLIP-seq
MIRT2375854	hsa-miR-652	CLIP-seq
MIRT2375841	hsa-miR-122	CLIP-seq
MIRT2375842	hsa-miR-130a	CLIP-seq
MIRT2375843	hsa-miR-130b	CLIP-seq
MIRT2375844	hsa-miR-301a	CLIP-seq
MIRT2375845	hsa-miR-301b	CLIP-seq
MIRT2375846	hsa-miR-3135b	CLIP-seq
MIRT2464071	hsa-miR-3149	CLIP-seq
MIRT2375847	hsa-miR-3652	CLIP-seq
MIRT2375848	hsa-miR-3666	CLIP-seq
MIRT2464072	hsa-miR-411	CLIP-seq
MIRT2375849	hsa-miR-4295	CLIP-seq
MIRT2464073	hsa-miR-4313	CLIP-seq
MIRT2375850	hsa-miR-4423-5p	CLIP-seq
MIRT2375851	hsa-miR-4430	CLIP-seq
MIRT2375852	hsa-miR-454	CLIP-seq
MIRT1517617	hsa-miR-4775	CLIP-seq
MIRT1517621	hsa-miR-590-3p	CLIP-seq
MIRT2375841	hsa-miR-122	CLIP-seq
MIRT2375846	hsa-miR-3135b	CLIP-seq
MIRT2375847	hsa-miR-3652	CLIP-seq
MIRT2375850	hsa-miR-4423-5p	CLIP-seq
MIRT2375851	hsa-miR-4430	CLIP-seq
MIRT2695771	hsa-miR-3185	CLIP-seq
MIRT2695772	hsa-miR-4709-3p	CLIP-seq

Gene ontology (GO) Show/Hide all (8)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IEA

Other IDs

• MIM: 618359
• HGNC: 12988
• e!Ensembl: ENSG00000186448

Protein

• UniProt ID: O14709
• Protein name: Zinc finger protein 197 (Zinc finger protein with KRAB and SCAN domains 9) (ZnF20) (pVHL-associated KRAB domain-containing protein)
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	818 → 840	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	902 → 924	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	734 → 756	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	482 → 504	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	426 → 448	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	566 → 588	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	622 → 644	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	454 → 476	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	958 → 980	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	538 → 560	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	678 → 700	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	930 → 952	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	846 → 868	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	874 → 896	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	398 → 420	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	594 → 616	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	706 → 728	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	650 → 672	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	790 → 812	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	510 → 532	Zinc finger, C2H2 type	Domain
  PF01352	KRAB	216 → 257	KRAB box	Family
  PF02023	SCAN	38 → 127	SCAN domain	Domain
  PF13912	zf-C2H2_6	762 → 787		Domain

• Sequence:

  MTRENVAHNALRQEGLVKGKDDTWKWGTSFQGSSSSVWETSHLHFRQLRYHETSGPQEAL
  SRLRELCRRWLRPEARTKAQILELLVLEQFLSILPGEIRTWVQLHHPGSGEEAVALVEEL
  QKDLDGPAIQVPVLVKDQDTLQKVVSAPGTTLPPVLPGSHIAAEICPHPPTDLVAFNLQD
  PQHDSPAPEASALSQEENPRNQLMALMLLTAQPQELVMFEEVSVCFTSEEWACLGPIQRA
  LYWDVMLENYGNVTSLEWETMTENEEVTSKPSSSQRADSHKGTSKRLQGSVPQVLDFEEE
  CEWQVLASQWGNETDERADTVKKVSLCERDKKKRTPPEKQGQKWKELGDSLTFGSAISES
  LIGTEGKKFYKCDMCCKHFNKISHLINHRRIHTGEKPHKCKECGKGFIQRSSLLMHLRNH
  SGEKPYKCNECGKAFSQSAYLLNHQRIHTGEKPYKCKECGKGFYRHSGLIIHLRRHSGER
  PYKCNECGKVFSQNAYLIDHQRLHKGEEPYKCNKCQKAFILKKSLILHQRIHSGEKPYKC
  DECGKTFAQTTYLIDHQRLHSAENPYKCKECGKVFIRSKSLLLHQRVHTEKKTFGCKKCG
  KIFSSKSNFIDHKRMHSREKPYKCTECGKAFTQSAYLFDHQRLHNGEKPYECNECGKVFI
  LKKSLILHQRFHTGENLYECKDCGKVFGSNRNLIDHERLHNGEKPYECRECGKTFIMSKS
  FMVHQKLHTQEKAYKCEDCGKAFSYNSSLLVHRRIHTGEKPFECSECGRAFSSNRNLIEH
  KRIHSGEKPYECDECGKCFILKKSLIGHQRIHTREKSYKCNDCGKVFSYRSNLIAHQRIH
  TGEKPYACSECGKGFTYNRNLIEHQRIHSGEKTYECHVCRKVLTSSRNLMVHQRIHTGEK
  PYKCNECGKDFSQNKNLVVHQRMHTGEKPYECDKCRKSFTSKRNLVGHQRIHTGEKPYGC
  NDCSKVFRQRKNLTVHQKIHTDEKPCECDVSEKEFSQTSNLHLQQKIHTIEEFSWLQNTN
  ESKIEIQKI

• Sequence length: 1029

Pathways

Reactome Pathway:

Generic Transcription Pathway

Related Genes

No strongly related genes found yet for ZNF197.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZNF197.