ZNF17 (zinc finger protein 17)

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Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 7565
• Gene name: Zinc finger protein 17
• Gene symbol: ZNF17
• Synonyms (NCBI Gene): HPF3, KOX10
• Chromosome: 19
• Chromosome location: 19q13.43

miRNA Show/Hide all (142)

miRTarBase ID	miRNA	Experiments	Reference
MIRT695088	hsa-miR-383-3p	HITS-CLIP	23313552
MIRT695087	hsa-miR-214-5p	HITS-CLIP	23313552
MIRT695086	hsa-miR-6811-3p	HITS-CLIP	23313552
MIRT695085	hsa-miR-6847-3p	HITS-CLIP	23313552
MIRT695084	hsa-miR-3926	HITS-CLIP	23313552
MIRT695083	hsa-miR-4284	HITS-CLIP	23313552
MIRT695082	hsa-miR-24-3p	HITS-CLIP	23313552
MIRT695081	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT695080	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT695079	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT695078	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT695077	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT695076	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT695075	hsa-miR-7977	HITS-CLIP	23313552
MIRT695074	hsa-miR-6514-3p	HITS-CLIP	23313552
MIRT695073	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT695072	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT695071	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT695070	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT695069	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT695068	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT695067	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT695066	hsa-miR-3689c	HITS-CLIP	23313552
MIRT695065	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT695064	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT695063	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT695062	hsa-miR-3122	HITS-CLIP	23313552
MIRT695061	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT695060	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT695059	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT459350	hsa-miR-4459	PAR-CLIP	23592263
MIRT459349	hsa-miR-665	PAR-CLIP	23592263
MIRT459348	hsa-miR-6134	PAR-CLIP	23592263
MIRT459347	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT459346	hsa-miR-6086	PAR-CLIP	23592263
MIRT459345	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT459343	hsa-miR-7154-3p	PAR-CLIP	23592263
MIRT459344	hsa-miR-765	PAR-CLIP	23592263
MIRT459342	hsa-miR-6894-5p	PAR-CLIP	23592263
MIRT459341	hsa-miR-3689d	PAR-CLIP	23592263
MIRT459340	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT459339	hsa-miR-6880-5p	PAR-CLIP	23592263
MIRT459337	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT459338	hsa-miR-6511b-5p	PAR-CLIP	23592263
MIRT459336	hsa-miR-6811-5p	PAR-CLIP	23592263
MIRT459335	hsa-miR-4724-5p	PAR-CLIP	23592263
MIRT459334	hsa-miR-6133	PAR-CLIP	23592263
MIRT726053	hsa-miR-92a-3p	HITS-CLIP	22473208
MIRT726052	hsa-miR-92b-3p	HITS-CLIP	22473208
MIRT726051	hsa-miR-32-5p	HITS-CLIP	22473208
MIRT695088	hsa-miR-383-3p	HITS-CLIP	23313552
MIRT695087	hsa-miR-214-5p	HITS-CLIP	23313552
MIRT695086	hsa-miR-6811-3p	HITS-CLIP	23313552
MIRT695085	hsa-miR-6847-3p	HITS-CLIP	23313552
MIRT695084	hsa-miR-3926	HITS-CLIP	23313552
MIRT695083	hsa-miR-4284	HITS-CLIP	23313552
MIRT695082	hsa-miR-24-3p	HITS-CLIP	23313552
MIRT695081	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT695080	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT695079	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT695078	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT695077	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT695076	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT695075	hsa-miR-7977	HITS-CLIP	23313552
MIRT695074	hsa-miR-6514-3p	HITS-CLIP	23313552
MIRT695073	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT695072	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT695071	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT695070	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT695069	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT695068	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT695067	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT695066	hsa-miR-3689c	HITS-CLIP	23313552
MIRT695065	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT695064	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT695063	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT695062	hsa-miR-3122	HITS-CLIP	23313552
MIRT695061	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT695060	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT695059	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT459350	hsa-miR-4459	PAR-CLIP	23592263
MIRT459349	hsa-miR-665	PAR-CLIP	23592263
MIRT459348	hsa-miR-6134	PAR-CLIP	23592263
MIRT459347	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT459346	hsa-miR-6086	PAR-CLIP	23592263
MIRT459345	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT459343	hsa-miR-7154-3p	PAR-CLIP	23592263
MIRT459344	hsa-miR-765	PAR-CLIP	23592263
MIRT459342	hsa-miR-6894-5p	PAR-CLIP	23592263
MIRT459341	hsa-miR-3689d	PAR-CLIP	23592263
MIRT459340	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT459339	hsa-miR-6880-5p	PAR-CLIP	23592263
MIRT459337	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT459338	hsa-miR-6511b-5p	PAR-CLIP	23592263
MIRT459336	hsa-miR-6811-5p	PAR-CLIP	23592263
MIRT459335	hsa-miR-4724-5p	PAR-CLIP	23592263
MIRT459334	hsa-miR-6133	PAR-CLIP	23592263
MIRT1517073	hsa-let-7a	CLIP-seq
MIRT1517074	hsa-let-7b	CLIP-seq
MIRT1517075	hsa-let-7c	CLIP-seq
MIRT1517076	hsa-let-7d	CLIP-seq
MIRT1517077	hsa-let-7e	CLIP-seq
MIRT1517078	hsa-let-7f	CLIP-seq
MIRT1517079	hsa-let-7g	CLIP-seq
MIRT1517080	hsa-let-7i	CLIP-seq
MIRT1517081	hsa-miR-101	CLIP-seq
MIRT1517082	hsa-miR-1257	CLIP-seq
MIRT1517083	hsa-miR-1278	CLIP-seq
MIRT1517084	hsa-miR-1284	CLIP-seq
MIRT1517085	hsa-miR-132	CLIP-seq
MIRT1517086	hsa-miR-202	CLIP-seq
MIRT1517087	hsa-miR-212	CLIP-seq
MIRT1517088	hsa-miR-25	CLIP-seq
MIRT1517089	hsa-miR-3143	CLIP-seq
MIRT1517090	hsa-miR-32	CLIP-seq
MIRT1517091	hsa-miR-363	CLIP-seq
MIRT1517092	hsa-miR-367	CLIP-seq
MIRT1517093	hsa-miR-382	CLIP-seq
MIRT1517094	hsa-miR-3923	CLIP-seq
MIRT1517095	hsa-miR-4282	CLIP-seq
MIRT1517096	hsa-miR-4317	CLIP-seq
MIRT1517097	hsa-miR-4426	CLIP-seq
MIRT1517098	hsa-miR-4458	CLIP-seq
MIRT1517099	hsa-miR-4500	CLIP-seq
MIRT1517100	hsa-miR-4539	CLIP-seq
MIRT1517101	hsa-miR-4647	CLIP-seq
MIRT1517102	hsa-miR-4662b	CLIP-seq
MIRT1517103	hsa-miR-4760-5p	CLIP-seq
MIRT1517104	hsa-miR-4777-5p	CLIP-seq
MIRT1517105	hsa-miR-4789-5p	CLIP-seq
MIRT1517106	hsa-miR-518d-5p	CLIP-seq
MIRT1517107	hsa-miR-519b-5p	CLIP-seq
MIRT1517108	hsa-miR-519c-5p	CLIP-seq
MIRT1517109	hsa-miR-520c-5p	CLIP-seq
MIRT1517110	hsa-miR-526a	CLIP-seq
MIRT1517111	hsa-miR-548u	CLIP-seq
MIRT1517112	hsa-miR-628-3p	CLIP-seq
MIRT1517113	hsa-miR-664	CLIP-seq
MIRT1517114	hsa-miR-92a	CLIP-seq
MIRT1517115	hsa-miR-92b	CLIP-seq
MIRT1517116	hsa-miR-941	CLIP-seq
MIRT1517117	hsa-miR-98	CLIP-seq

Gene ontology (GO) Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 619254
• HGNC: 12958
• e!Ensembl: ENSG00000186272

Protein

• UniProt ID: P17021
• Protein name: Zinc finger protein 17 (Zinc finger protein HPF3) (Zinc finger protein KOX10)
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	554 → 576	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	638 → 660	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	610 → 632	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	386 → 408	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	218 → 240	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	274 → 296	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	246 → 268	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	470 → 492	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	582 → 604	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	414 → 436	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	442 → 464	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	302 → 324	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	330 → 352	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	498 → 520	Zinc finger, C2H2 type	Domain
  PF01352	KRAB	7 → 48	KRAB box	Family

• Sequence:

  MNLTEDYMVFEDVAIHFSQEEWGILNDVQRHLHSDVMLENFALLSSVGCWHGAKDEEAPS
  KQCVSVGVSQVTTLKPALSTQKAQPCETCSSLLKDILHLAEHDGTHPKRTAKLYLHQKEH
  LREKLTRSDEGRPSFVNDSVHLAKRNLTCMQGGKDFTGDSDLQQQALHSGWKPHRDTHGV
  EAFQSGQNNYSCTQCGKDFCHQHTLFEHQKIHTEERPYECSECGKLFRYNSDLIKHQRNH
  TGERPYKCSECGKAFSLKYNVVQHQKIHTGERPYECSECGKAFLRKSHLLQHQRIHTRPR
  PYVCSECGKAFLTQAHLVGHQKIHTGERPYGCNECGKYFMYSSALIRHQKVHTGERPFYC
  CECGKFFMDSCTLIIHQRVHTGEKPYECNECGKFFRYRSTLIRHQKVHTGEKPYECSECG
  KFFMDTSTLIIHQRVHTGEKPYECNKCGKFFRYCFTLNRHQRVHSGERPYECSECGKFFV
  DSCTLKSHQRVHTGERPFECSICGKSFRCRSTLDTHQRIHTGERPYECSECGKFFRHNSN
  HIRHRRNHFGERSFECTECGRVFSQNSHLIRHQKVHTRERTYKCSKCGKFFMDSSTLISH
  ERVHTGEKPYECSECGKVFRYNSSLIKHRRIHTGERPYQCSECGRVFNQNSHLIQHQKVH
  TR

• Sequence length: 662

Pathways

Reactome Pathway:

Generic Transcription Pathway

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
ZNF17-related disorder	Uncertain significance; Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Ciliopathies	Ciliopathy	Pubtator	28800606	Associate	★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for ZNF17.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZNF17.