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Gene Gene information from NCBI Gene database.
Entrez ID 7710
Gene name Zinc finger protein 154
Gene symbol ZNF154
Synonyms (NCBI Gene)
pHZ-92
Chromosome 19
Chromosome location 19q13.43
Summary This gene encodes a protein that belongs to the zinc finger Kruppel family of transcriptional regulators, whose members are thought to function in normal and abnormal cell growth and differentiation. Hypermethylation of this gene is associated with the re
miRNA miRNA information provided by mirtarbase database.
1317 Show/Hide all (1317)
miRTarBase ID miRNA Experiments Reference
MIRT712794 hsa-miR-634 HITS-CLIP 19536157
MIRT712793 hsa-miR-370-5p HITS-CLIP 19536157
MIRT712792 hsa-miR-1226-3p HITS-CLIP 19536157
MIRT712791 hsa-miR-4733-3p HITS-CLIP 19536157
MIRT712790 hsa-miR-922 HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
10 Show/Hide all (10)
GO ID Ontology Definition Evidence Reference
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0003677 Function DNA binding IEA
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
604085 12939 ENSG00000179909
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q13106
Protein name Zinc finger protein 154
Protein function May be involved in transcriptional regulation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00096 zf-C2H2 413 → 435 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 385 → 407 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 189 → 211 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 357 → 379 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 301 → 323 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 217 → 239 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 161 → 183 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 329 → 351 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 245 → 267 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 273 → 295 Zinc finger, C2H2 type Domain
PF01352 KRAB 13 → 54 KRAB box Family
Sequence
Sequence length 437
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Generic Transcription Pathway
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Reference Evidence Score
Melanoma Uncertain significance ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Show/Hide Text Mining Associations (29)
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Alzheimer Disease Alzheimer disease Pubtator 40244264 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Ankylosing spondylitis Ankylosing Spondylitis BEFREE 26610302
★★★★★
★☆☆☆☆
Found in Text Mining only
Bladder Neoplasm Bladder Neoplasm BEFREE 23056278
★★★★★
★☆☆☆☆
Found in Text Mining only
Breast Neoplasms Breast neoplasm Pubtator 34452548 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Carcinoma Endometrioid Endometrioid carcinoma Pubtator 29060924 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Carcinoma of bladder Bladder carcinoma BEFREE 23056278
★★★★★
★☆☆☆☆
Found in Text Mining only
Carcinoma Renal Cell Renal cell carcinoma Pubtator 22610075, 25332168 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Endometrial Carcinoma Endometrial carcinoma BEFREE 29027401
★★★★★
★☆☆☆☆
Found in Text Mining only
Endometrial Neoplasms Endometrial neoplasm Pubtator 29027401 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Epithelioma Epithelioma BEFREE 26857064
★★★★★
★☆☆☆☆
Found in Text Mining only