ZIK1 (zinc finger protein interacting with K protein 1)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 284307
• Gene name: Zinc finger protein interacting with K protein 1
• Gene symbol: ZIK1
• Synonyms (NCBI Gene): ZNF762
• Chromosome: 19
• Chromosome location: 19q13.43

miRNA Show/Hide all (103)

miRTarBase ID	miRNA	Experiments	Reference
MIRT051036	hsa-miR-17-5p	CLASH	23622248
MIRT561262	hsa-miR-4680-5p	PAR-CLIP	20371350
MIRT552512	hsa-miR-3925-5p	PAR-CLIP	20371350
MIRT552511	hsa-miR-3123	PAR-CLIP	20371350
MIRT552510	hsa-miR-183-5p	PAR-CLIP	20371350
MIRT552509	hsa-miR-3668	PAR-CLIP	20371350
MIRT552508	hsa-miR-539-5p	PAR-CLIP	20371350
MIRT552507	hsa-miR-31-5p	PAR-CLIP	20371350
MIRT552506	hsa-miR-6809-5p	PAR-CLIP	20371350
MIRT552505	hsa-miR-6832-5p	PAR-CLIP	20371350
MIRT552504	hsa-miR-4732-5p	PAR-CLIP	20371350
MIRT552503	hsa-miR-3653-3p	PAR-CLIP	20371350
MIRT561262	hsa-miR-4680-5p	PAR-CLIP	20371350
MIRT552512	hsa-miR-3925-5p	PAR-CLIP	21572407
MIRT552511	hsa-miR-3123	PAR-CLIP	21572407
MIRT552510	hsa-miR-183-5p	PAR-CLIP	21572407
MIRT552509	hsa-miR-3668	PAR-CLIP	21572407
MIRT552508	hsa-miR-539-5p	PAR-CLIP	21572407
MIRT552507	hsa-miR-31-5p	PAR-CLIP	21572407
MIRT552506	hsa-miR-6809-5p	PAR-CLIP	21572407
MIRT552505	hsa-miR-6832-5p	PAR-CLIP	21572407
MIRT552504	hsa-miR-4732-5p	PAR-CLIP	21572407
MIRT552503	hsa-miR-3653-3p	PAR-CLIP	21572407
MIRT552502	hsa-miR-130a-5p	PAR-CLIP	21572407
MIRT552501	hsa-miR-23a-3p	PAR-CLIP	21572407
MIRT552500	hsa-miR-23b-3p	PAR-CLIP	21572407
MIRT552499	hsa-miR-23c	PAR-CLIP	21572407
MIRT561262	hsa-miR-4680-5p	PAR-CLIP	20371350
MIRT552512	hsa-miR-3925-5p	PAR-CLIP	20371350
MIRT552511	hsa-miR-3123	PAR-CLIP	20371350
MIRT552510	hsa-miR-183-5p	PAR-CLIP	20371350
MIRT552509	hsa-miR-3668	PAR-CLIP	20371350
MIRT552508	hsa-miR-539-5p	PAR-CLIP	20371350
MIRT552507	hsa-miR-31-5p	PAR-CLIP	20371350
MIRT552506	hsa-miR-6809-5p	PAR-CLIP	20371350
MIRT552505	hsa-miR-6832-5p	PAR-CLIP	20371350
MIRT552504	hsa-miR-4732-5p	PAR-CLIP	20371350
MIRT552503	hsa-miR-3653-3p	PAR-CLIP	20371350
MIRT561262	hsa-miR-4680-5p	PAR-CLIP	20371350
MIRT552512	hsa-miR-3925-5p	PAR-CLIP	21572407
MIRT552511	hsa-miR-3123	PAR-CLIP	21572407
MIRT552510	hsa-miR-183-5p	PAR-CLIP	21572407
MIRT552509	hsa-miR-3668	PAR-CLIP	21572407
MIRT552508	hsa-miR-539-5p	PAR-CLIP	21572407
MIRT552507	hsa-miR-31-5p	PAR-CLIP	21572407
MIRT552506	hsa-miR-6809-5p	PAR-CLIP	21572407
MIRT552505	hsa-miR-6832-5p	PAR-CLIP	21572407
MIRT552504	hsa-miR-4732-5p	PAR-CLIP	21572407
MIRT552503	hsa-miR-3653-3p	PAR-CLIP	21572407
MIRT552502	hsa-miR-130a-5p	PAR-CLIP	21572407
MIRT552501	hsa-miR-23a-3p	PAR-CLIP	21572407
MIRT552500	hsa-miR-23b-3p	PAR-CLIP	21572407
MIRT552499	hsa-miR-23c	PAR-CLIP	21572407
MIRT1513598	hsa-miR-221	CLIP-seq
MIRT1513599	hsa-miR-222	CLIP-seq
MIRT1513600	hsa-miR-338-5p	CLIP-seq
MIRT1513601	hsa-miR-3612	CLIP-seq
MIRT1513602	hsa-miR-3652	CLIP-seq
MIRT1513603	hsa-miR-3671	CLIP-seq
MIRT1513604	hsa-miR-3927	CLIP-seq
MIRT1513605	hsa-miR-4430	CLIP-seq
MIRT1513606	hsa-miR-4443	CLIP-seq
MIRT1513607	hsa-miR-4797-5p	CLIP-seq
MIRT1513608	hsa-miR-4802-5p	CLIP-seq
MIRT1513609	hsa-miR-485-5p	CLIP-seq
MIRT1513610	hsa-miR-548v	CLIP-seq
MIRT1513611	hsa-miR-552	CLIP-seq
MIRT1513612	hsa-miR-607	CLIP-seq
MIRT1513613	hsa-miR-650	CLIP-seq
MIRT1513614	hsa-miR-7	CLIP-seq
MIRT2154774	hsa-miR-151-3p	CLIP-seq
MIRT2154775	hsa-miR-15a	CLIP-seq
MIRT2154776	hsa-miR-15b	CLIP-seq
MIRT2154777	hsa-miR-16	CLIP-seq
MIRT2154778	hsa-miR-195	CLIP-seq
MIRT2154779	hsa-miR-214	CLIP-seq
MIRT2154780	hsa-miR-3119	CLIP-seq
MIRT2154781	hsa-miR-3619-5p	CLIP-seq
MIRT2154782	hsa-miR-3913-3p	CLIP-seq
MIRT2154783	hsa-miR-424	CLIP-seq
MIRT2154784	hsa-miR-4291	CLIP-seq
MIRT2154785	hsa-miR-4463	CLIP-seq
MIRT2154786	hsa-miR-4484	CLIP-seq
MIRT2154787	hsa-miR-4499	CLIP-seq
MIRT2154788	hsa-miR-4509	CLIP-seq
MIRT2154789	hsa-miR-4684-5p	CLIP-seq
MIRT2154790	hsa-miR-4744	CLIP-seq
MIRT2154791	hsa-miR-4768-5p	CLIP-seq
MIRT2154792	hsa-miR-489	CLIP-seq
MIRT2154793	hsa-miR-497	CLIP-seq
MIRT2154794	hsa-miR-548an	CLIP-seq
MIRT2154795	hsa-miR-670	CLIP-seq
MIRT2154796	hsa-miR-761	CLIP-seq
MIRT2154797	hsa-miR-922	CLIP-seq
MIRT2154797	hsa-miR-922	CLIP-seq
MIRT1513601	hsa-miR-3612	CLIP-seq
MIRT1513602	hsa-miR-3652	CLIP-seq
MIRT1513605	hsa-miR-4430	CLIP-seq
MIRT1513606	hsa-miR-4443	CLIP-seq
MIRT1513608	hsa-miR-4802-5p	CLIP-seq
MIRT1513609	hsa-miR-485-5p	CLIP-seq
MIRT1513613	hsa-miR-650	CLIP-seq
MIRT1513614	hsa-miR-7	CLIP-seq

Gene ontology (GO) Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	32814053
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0060255	Process	Regulation of macromolecule metabolic process	IEA
GO:0080090	Process	Regulation of primary metabolic process	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q3SY52
• Protein name: Zinc finger protein interacting with ribonucleoprotein K (Zinc finger protein 762)
• Protein function: May be a transcriptional repressor.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	379 → 401	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	323 → 345	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	239 → 261	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	407 → 429	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	435 → 457	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	267 → 289	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	295 → 317	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	351 → 373	Zinc finger, C2H2 type	Domain
  PF01352	KRAB	26 → 67	KRAB box	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed at high levels in gastric glands, and at low levels in colon and small intestine. Silenced through promoter methylation in gastric glands with intestinal metaplasia. {ECO:0000269|PubMed:17071588}.
• Sequence:

  MAAAALRAPTQVTVSPETHMDLTKGCVTFEDIAIYFSQDEWGLLDEAQRLLYLEVMLENF
  ALVASLGCGHGTEDEETPSDQNVSVGVSQSKAGSSTQKTQSCEMCVPVLKDILHLADLPG
  QKPYLVGECTNHHQHQKHHSAKKSLKRDMDRASYVKCCLFCMSLKPFRKWEVGKDLPAML
  RLLRSLVFPGGKKPGTITECGEDIRSQKSHYKSGECGKASRHKHTPVYHPRVYTGKKLYE
  CSKCGKAFRGKYSLVQHQRVHTGERPWECNECGKFFSQTSHLNDHRRIHTGERPYECSEC
  GKLFRQNSSLVDHQKIHTGARPYECSQCGKSFSQKATLVKHQRVHTGERPYKCGECGNSF
  SQSAILNQHRRIHTGAKPYECGQCGKSFSQKATLIKHQRVHTGERPYKCGDCGKSFSQSS
  ILIQHRRIHTGARPYECGQCGKSFSQKSGLIQHQVVHTGERPYECNKCGNSFSQCSSLIH
  HQKCHNT

• Sequence length: 487

Pathways

Reactome Pathway:

Generic Transcription Pathway

Related Genes

No strongly related genes found yet for ZIK1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZIK1.