Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	11244
Gene name	Zinc fingers and homeoboxes 1
Gene symbol	ZHX1
Synonyms (NCBI Gene)	-
Chromosome	8
Chromosome location	8q24.13
Summary	The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This g

320 Show/Hide all (320)

miRTarBase ID	miRNA	Experiments	Reference
MIRT002558	hsa-miR-373-3p	Microarray	15685193
MIRT002558	hsa-miR-373-3p	Microarray;Other	15685193
MIRT027040	hsa-miR-103a-3p	Sequencing	20371350
MIRT028258	hsa-miR-32-5p	Sequencing	20371350
MIRT054230	hsa-miR-199a-3p	FlowImmunohistochemistryLuciferase reporter assayqRT-PCRWestern blot	25448600
MIRT054230	hsa-miR-199a-3p	FlowImmunohistochemistryLuciferase reporter assayqRT-PCRWestern blot	25448600
MIRT609986	hsa-miR-660-5p	HITS-CLIP	23313552
MIRT615380	hsa-miR-6823-5p	HITS-CLIP	23313552
MIRT609985	hsa-miR-5591-3p	HITS-CLIP	23313552
MIRT609984	hsa-miR-2681-5p	HITS-CLIP	23313552
MIRT609986	hsa-miR-660-5p	HITS-CLIP	23824327
MIRT609985	hsa-miR-5591-3p	HITS-CLIP	23824327
MIRT609984	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT609986	hsa-miR-660-5p	HITS-CLIP	23824327
MIRT615380	hsa-miR-6823-5p	HITS-CLIP	23824327
MIRT609985	hsa-miR-5591-3p	HITS-CLIP	23824327
MIRT224212	hsa-miR-4263	HITS-CLIP	23824327
MIRT224210	hsa-miR-576-5p	HITS-CLIP	23824327
MIRT609984	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT609986	hsa-miR-660-5p	HITS-CLIP	23824327
MIRT609985	hsa-miR-5591-3p	HITS-CLIP	23824327
MIRT609984	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT609986	hsa-miR-660-5p	HITS-CLIP	23824327
MIRT609985	hsa-miR-5591-3p	HITS-CLIP	23824327
MIRT609984	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT609984	hsa-miR-2681-5p	HITS-CLIP	27418678
MIRT609984	hsa-miR-2681-5p	HITS-CLIP	27418678
MIRT609984	hsa-miR-2681-5p	HITS-CLIP	27418678
MIRT609984	hsa-miR-2681-5p	HITS-CLIP	27418678
MIRT224212	hsa-miR-4263	HITS-CLIP	27418678
MIRT224212	hsa-miR-4263	HITS-CLIP	27418678
MIRT224212	hsa-miR-4263	HITS-CLIP	27418678
MIRT609985	hsa-miR-5591-3p	HITS-CLIP	27418678
MIRT609985	hsa-miR-5591-3p	HITS-CLIP	27418678
MIRT609985	hsa-miR-5591-3p	HITS-CLIP	27418678
MIRT609985	hsa-miR-5591-3p	HITS-CLIP	27418678
MIRT224210	hsa-miR-576-5p	HITS-CLIP	27418678
MIRT224210	hsa-miR-576-5p	HITS-CLIP	27418678
MIRT224210	hsa-miR-576-5p	HITS-CLIP	27418678
MIRT609986	hsa-miR-660-5p	HITS-CLIP	27418678
MIRT609986	hsa-miR-660-5p	HITS-CLIP	27418678
MIRT609986	hsa-miR-660-5p	HITS-CLIP	27418678
MIRT609986	hsa-miR-660-5p	HITS-CLIP	27418678
MIRT615380	hsa-miR-6823-5p	HITS-CLIP	27418678
MIRT609986	hsa-miR-660-5p	HITS-CLIP	23313552
MIRT615380	hsa-miR-6823-5p	HITS-CLIP	23313552
MIRT609985	hsa-miR-5591-3p	HITS-CLIP	23313552
MIRT609984	hsa-miR-2681-5p	HITS-CLIP	23313552
MIRT609986	hsa-miR-660-5p	HITS-CLIP	23824327
MIRT609985	hsa-miR-5591-3p	HITS-CLIP	23824327
MIRT609984	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT609986	hsa-miR-660-5p	HITS-CLIP	23824327
MIRT615380	hsa-miR-6823-5p	HITS-CLIP	23824327
MIRT609985	hsa-miR-5591-3p	HITS-CLIP	23824327
MIRT224212	hsa-miR-4263	HITS-CLIP	23824327
MIRT224210	hsa-miR-576-5p	HITS-CLIP	23824327
MIRT609984	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT609986	hsa-miR-660-5p	HITS-CLIP	23824327
MIRT609985	hsa-miR-5591-3p	HITS-CLIP	23824327
MIRT609984	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT609986	hsa-miR-660-5p	HITS-CLIP	23824327
MIRT609985	hsa-miR-5591-3p	HITS-CLIP	23824327
MIRT609984	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT1512896	hsa-miR-103a	CLIP-seq
MIRT1512897	hsa-miR-107	CLIP-seq
MIRT1512898	hsa-miR-1183	CLIP-seq
MIRT1512899	hsa-miR-1224-5p	CLIP-seq
MIRT1512900	hsa-miR-1244	CLIP-seq
MIRT1512901	hsa-miR-1269	CLIP-seq
MIRT1512902	hsa-miR-1269b	CLIP-seq
MIRT1512903	hsa-miR-1271	CLIP-seq
MIRT1512904	hsa-miR-1288	CLIP-seq
MIRT1512905	hsa-miR-1301	CLIP-seq
MIRT1512906	hsa-miR-1305	CLIP-seq
MIRT1512907	hsa-miR-132	CLIP-seq
MIRT1512908	hsa-miR-140-5p	CLIP-seq
MIRT1512909	hsa-miR-182	CLIP-seq
MIRT1512910	hsa-miR-194	CLIP-seq
MIRT1512911	hsa-miR-199b-3p	CLIP-seq
MIRT1512912	hsa-miR-200b	CLIP-seq
MIRT1512913	hsa-miR-200c	CLIP-seq
MIRT1512914	hsa-miR-212	CLIP-seq
MIRT1512915	hsa-miR-221	CLIP-seq
MIRT1512916	hsa-miR-222	CLIP-seq
MIRT1512917	hsa-miR-298	CLIP-seq
MIRT1512918	hsa-miR-29a	CLIP-seq
MIRT1512919	hsa-miR-29b	CLIP-seq
MIRT1512920	hsa-miR-29c	CLIP-seq
MIRT1512921	hsa-miR-3065-3p	CLIP-seq
MIRT1512922	hsa-miR-3120-5p	CLIP-seq
MIRT1512923	hsa-miR-3129-5p	CLIP-seq
MIRT1512924	hsa-miR-3189-5p	CLIP-seq
MIRT1512925	hsa-miR-3545-5p	CLIP-seq
MIRT1512926	hsa-miR-3607-3p	CLIP-seq
MIRT1512927	hsa-miR-3654	CLIP-seq
MIRT1512928	hsa-miR-3671	CLIP-seq
MIRT1512929	hsa-miR-3673	CLIP-seq
MIRT1512930	hsa-miR-3678-3p	CLIP-seq
MIRT1512931	hsa-miR-378	CLIP-seq
MIRT1512932	hsa-miR-378b	CLIP-seq
MIRT1512933	hsa-miR-378c	CLIP-seq
MIRT1512934	hsa-miR-378d	CLIP-seq
MIRT1512935	hsa-miR-378e	CLIP-seq
MIRT1512936	hsa-miR-378f	CLIP-seq
MIRT1512937	hsa-miR-378h	CLIP-seq
MIRT1512938	hsa-miR-378i	CLIP-seq
MIRT1512939	hsa-miR-3915	CLIP-seq
MIRT1512940	hsa-miR-3928	CLIP-seq
MIRT1512941	hsa-miR-422a	CLIP-seq
MIRT1512942	hsa-miR-4272	CLIP-seq
MIRT1512943	hsa-miR-429	CLIP-seq
MIRT1512944	hsa-miR-4310	CLIP-seq
MIRT1512945	hsa-miR-4418	CLIP-seq
MIRT1512946	hsa-miR-4427	CLIP-seq
MIRT1512947	hsa-miR-4460	CLIP-seq
MIRT1512948	hsa-miR-4515	CLIP-seq
MIRT1512949	hsa-miR-4517	CLIP-seq
MIRT1512950	hsa-miR-4640-3p	CLIP-seq
MIRT1512951	hsa-miR-4682	CLIP-seq
MIRT1512952	hsa-miR-4693-5p	CLIP-seq
MIRT1512953	hsa-miR-4699-3p	CLIP-seq
MIRT1512954	hsa-miR-4740-5p	CLIP-seq
MIRT1512955	hsa-miR-4751	CLIP-seq
MIRT1512956	hsa-miR-4758-3p	CLIP-seq
MIRT1512957	hsa-miR-4765	CLIP-seq
MIRT1512958	hsa-miR-489	CLIP-seq
MIRT1512959	hsa-miR-5047	CLIP-seq
MIRT1512960	hsa-miR-509-3-5p	CLIP-seq
MIRT1512961	hsa-miR-509-5p	CLIP-seq
MIRT1512962	hsa-miR-520d-5p	CLIP-seq
MIRT1512963	hsa-miR-524-5p	CLIP-seq
MIRT1512964	hsa-miR-561	CLIP-seq
MIRT1512965	hsa-miR-579	CLIP-seq
MIRT1512966	hsa-miR-580	CLIP-seq
MIRT1512967	hsa-miR-607	CLIP-seq
MIRT1512968	hsa-miR-626	CLIP-seq
MIRT1512969	hsa-miR-660	CLIP-seq
MIRT1512970	hsa-miR-802	CLIP-seq
MIRT1512971	hsa-miR-936	CLIP-seq
MIRT1512972	hsa-miR-96	CLIP-seq
MIRT1512896	hsa-miR-103a	CLIP-seq
MIRT1512897	hsa-miR-107	CLIP-seq
MIRT1512900	hsa-miR-1244	CLIP-seq
MIRT1512903	hsa-miR-1271	CLIP-seq
MIRT1512973	hsa-miR-128	CLIP-seq
MIRT1512905	hsa-miR-1301	CLIP-seq
MIRT1512974	hsa-miR-130a	CLIP-seq
MIRT1512975	hsa-miR-130b	CLIP-seq
MIRT1512907	hsa-miR-132	CLIP-seq
MIRT1512976	hsa-miR-1324	CLIP-seq
MIRT1512977	hsa-miR-141	CLIP-seq
MIRT1512978	hsa-miR-15a	CLIP-seq
MIRT1512979	hsa-miR-15b	CLIP-seq
MIRT1512980	hsa-miR-16	CLIP-seq
MIRT1512909	hsa-miR-182	CLIP-seq
MIRT1512910	hsa-miR-194	CLIP-seq
MIRT1512981	hsa-miR-195	CLIP-seq
MIRT1512982	hsa-miR-1976	CLIP-seq
MIRT1512911	hsa-miR-199b-3p	CLIP-seq
MIRT1512983	hsa-miR-200a	CLIP-seq
MIRT1512914	hsa-miR-212	CLIP-seq
MIRT1512915	hsa-miR-221	CLIP-seq
MIRT1512916	hsa-miR-222	CLIP-seq
MIRT1512984	hsa-miR-23a	CLIP-seq
MIRT1512985	hsa-miR-23b	CLIP-seq
MIRT1512986	hsa-miR-23c	CLIP-seq
MIRT1512987	hsa-miR-27a	CLIP-seq
MIRT1512988	hsa-miR-27b	CLIP-seq
MIRT1512917	hsa-miR-298	CLIP-seq
MIRT1512989	hsa-miR-301a	CLIP-seq
MIRT1512990	hsa-miR-301b	CLIP-seq
MIRT1512991	hsa-miR-3074-5p	CLIP-seq
MIRT1512992	hsa-miR-31	CLIP-seq
MIRT1512993	hsa-miR-3119	CLIP-seq
MIRT1512923	hsa-miR-3129-5p	CLIP-seq
MIRT1512994	hsa-miR-3163	CLIP-seq
MIRT1512995	hsa-miR-340	CLIP-seq
MIRT1512996	hsa-miR-3646	CLIP-seq
MIRT1512997	hsa-miR-3662	CLIP-seq
MIRT1512998	hsa-miR-3666	CLIP-seq
MIRT1512929	hsa-miR-3673	CLIP-seq
MIRT1512930	hsa-miR-3678-3p	CLIP-seq
MIRT1512939	hsa-miR-3915	CLIP-seq
MIRT1512999	hsa-miR-3922-5p	CLIP-seq
MIRT1512940	hsa-miR-3928	CLIP-seq
MIRT1513000	hsa-miR-3977	CLIP-seq
MIRT1513001	hsa-miR-424	CLIP-seq
MIRT1512942	hsa-miR-4272	CLIP-seq
MIRT1513002	hsa-miR-4295	CLIP-seq
MIRT1512944	hsa-miR-4310	CLIP-seq
MIRT1512945	hsa-miR-4418	CLIP-seq
MIRT1513003	hsa-miR-4424	CLIP-seq
MIRT1513004	hsa-miR-4473	CLIP-seq
MIRT1513005	hsa-miR-448	CLIP-seq
MIRT1513006	hsa-miR-454	CLIP-seq
MIRT1513007	hsa-miR-4671-3p	CLIP-seq
MIRT1512953	hsa-miR-4699-3p	CLIP-seq
MIRT1513008	hsa-miR-497	CLIP-seq
MIRT1512959	hsa-miR-5047	CLIP-seq
MIRT1512960	hsa-miR-509-3-5p	CLIP-seq
MIRT1512961	hsa-miR-509-5p	CLIP-seq
MIRT1513009	hsa-miR-513a-5p	CLIP-seq
MIRT1513010	hsa-miR-548al	CLIP-seq
MIRT1513011	hsa-miR-548c-3p	CLIP-seq
MIRT1512964	hsa-miR-561	CLIP-seq
MIRT1513012	hsa-miR-622	CLIP-seq
MIRT1513013	hsa-miR-664	CLIP-seq
MIRT1512971	hsa-miR-936	CLIP-seq
MIRT1512972	hsa-miR-96	CLIP-seq
MIRT1512969	hsa-miR-660	CLIP-seq
MIRT1512969	hsa-miR-660	CLIP-seq
MIRT1512969	hsa-miR-660	CLIP-seq
MIRT1512896	hsa-miR-103a	CLIP-seq
MIRT1512897	hsa-miR-107	CLIP-seq
MIRT1512900	hsa-miR-1244	CLIP-seq
MIRT1512905	hsa-miR-1301	CLIP-seq
MIRT1512908	hsa-miR-140-5p	CLIP-seq
MIRT1512911	hsa-miR-199b-3p	CLIP-seq
MIRT1512915	hsa-miR-221	CLIP-seq
MIRT1512916	hsa-miR-222	CLIP-seq
MIRT1512923	hsa-miR-3129-5p	CLIP-seq
MIRT1512925	hsa-miR-3545-5p	CLIP-seq
MIRT2154488	hsa-miR-3660	CLIP-seq
MIRT2154489	hsa-miR-3692	CLIP-seq
MIRT2154490	hsa-miR-3920	CLIP-seq
MIRT1512944	hsa-miR-4310	CLIP-seq
MIRT1512945	hsa-miR-4418	CLIP-seq
MIRT1512947	hsa-miR-4460	CLIP-seq
MIRT2154491	hsa-miR-4526	CLIP-seq
MIRT1512953	hsa-miR-4699-3p	CLIP-seq
MIRT2154492	hsa-miR-4762-3p	CLIP-seq
MIRT1512959	hsa-miR-5047	CLIP-seq
MIRT2154493	hsa-miR-508-3p	CLIP-seq
MIRT1512960	hsa-miR-509-3-5p	CLIP-seq
MIRT1512961	hsa-miR-509-5p	CLIP-seq
MIRT2154494	hsa-miR-568	CLIP-seq
MIRT2154495	hsa-miR-570	CLIP-seq
MIRT2154496	hsa-miR-1279	CLIP-seq
MIRT1512911	hsa-miR-199b-3p	CLIP-seq
MIRT1512923	hsa-miR-3129-5p	CLIP-seq
MIRT2154497	hsa-miR-4797-5p	CLIP-seq
MIRT2154498	hsa-miR-543	CLIP-seq
MIRT1512896	hsa-miR-103a	CLIP-seq
MIRT1512897	hsa-miR-107	CLIP-seq
MIRT1512900	hsa-miR-1244	CLIP-seq
MIRT1512905	hsa-miR-1301	CLIP-seq
MIRT1512982	hsa-miR-1976	CLIP-seq
MIRT1512911	hsa-miR-199b-3p	CLIP-seq
MIRT1512915	hsa-miR-221	CLIP-seq
MIRT1512916	hsa-miR-222	CLIP-seq
MIRT1512917	hsa-miR-298	CLIP-seq
MIRT1512992	hsa-miR-31	CLIP-seq
MIRT1512923	hsa-miR-3129-5p	CLIP-seq
MIRT1512930	hsa-miR-3678-3p	CLIP-seq
MIRT2154489	hsa-miR-3692	CLIP-seq
MIRT1512939	hsa-miR-3915	CLIP-seq
MIRT2154490	hsa-miR-3920	CLIP-seq
MIRT1512940	hsa-miR-3928	CLIP-seq
MIRT1512944	hsa-miR-4310	CLIP-seq
MIRT1512945	hsa-miR-4418	CLIP-seq
MIRT1513003	hsa-miR-4424	CLIP-seq
MIRT2154492	hsa-miR-4762-3p	CLIP-seq
MIRT1512959	hsa-miR-5047	CLIP-seq
MIRT2154493	hsa-miR-508-3p	CLIP-seq
MIRT1512960	hsa-miR-509-3-5p	CLIP-seq
MIRT1512961	hsa-miR-509-5p	CLIP-seq
MIRT1513010	hsa-miR-548al	CLIP-seq
MIRT2154494	hsa-miR-568	CLIP-seq
MIRT1513012	hsa-miR-622	CLIP-seq
MIRT2374692	hsa-miR-4282	CLIP-seq
MIRT1512953	hsa-miR-4699-3p	CLIP-seq
MIRT2154497	hsa-miR-4797-5p	CLIP-seq
MIRT1512900	hsa-miR-1244	CLIP-seq
MIRT1512903	hsa-miR-1271	CLIP-seq
MIRT2154496	hsa-miR-1279	CLIP-seq
MIRT2397400	hsa-miR-136	CLIP-seq
MIRT1512909	hsa-miR-182	CLIP-seq
MIRT1512911	hsa-miR-199b-3p	CLIP-seq
MIRT1512923	hsa-miR-3129-5p	CLIP-seq
MIRT1512972	hsa-miR-96	CLIP-seq
MIRT1512969	hsa-miR-660	CLIP-seq
MIRT2667265	hsa-miR-1225-5p	CLIP-seq
MIRT1512906	hsa-miR-1305	CLIP-seq
MIRT1512907	hsa-miR-132	CLIP-seq
MIRT1512977	hsa-miR-141	CLIP-seq
MIRT1512983	hsa-miR-200a	CLIP-seq
MIRT1512914	hsa-miR-212	CLIP-seq
MIRT1512992	hsa-miR-31	CLIP-seq
MIRT2667266	hsa-miR-3140-3p	CLIP-seq
MIRT1512924	hsa-miR-3189-5p	CLIP-seq
MIRT2667267	hsa-miR-3659	CLIP-seq
MIRT2154489	hsa-miR-3692	CLIP-seq
MIRT2667268	hsa-miR-370	CLIP-seq
MIRT2154490	hsa-miR-3920	CLIP-seq
MIRT1513003	hsa-miR-4424	CLIP-seq
MIRT2667269	hsa-miR-4658	CLIP-seq
MIRT1512956	hsa-miR-4758-3p	CLIP-seq
MIRT2667270	hsa-miR-4758-5p	CLIP-seq
MIRT2154492	hsa-miR-4762-3p	CLIP-seq
MIRT2154493	hsa-miR-508-3p	CLIP-seq
MIRT1513010	hsa-miR-548al	CLIP-seq
MIRT2154494	hsa-miR-568	CLIP-seq
MIRT2154495	hsa-miR-570	CLIP-seq
MIRT2667271	hsa-miR-574-5p	CLIP-seq
MIRT2667265	hsa-miR-1225-5p	CLIP-seq
MIRT1512907	hsa-miR-132	CLIP-seq
MIRT1512977	hsa-miR-141	CLIP-seq
MIRT1512983	hsa-miR-200a	CLIP-seq
MIRT1512914	hsa-miR-212	CLIP-seq
MIRT1512992	hsa-miR-31	CLIP-seq
MIRT2667266	hsa-miR-3140-3p	CLIP-seq
MIRT1512924	hsa-miR-3189-5p	CLIP-seq
MIRT2667267	hsa-miR-3659	CLIP-seq
MIRT2667268	hsa-miR-370	CLIP-seq
MIRT1513003	hsa-miR-4424	CLIP-seq
MIRT2667269	hsa-miR-4658	CLIP-seq
MIRT1512956	hsa-miR-4758-3p	CLIP-seq
MIRT2667270	hsa-miR-4758-5p	CLIP-seq
MIRT1513010	hsa-miR-548al	CLIP-seq
MIRT2667271	hsa-miR-574-5p	CLIP-seq

19 Show/Hide all (19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	17303076
GO:0000785	Component	Chromatin	ISA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IDA	12237128
GO:0005515	Function	Protein binding	IPI	10571058, 12659632, 12741956, 16713569, 17303076, 21988832, 26496610, 32814053, 35044719
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	17056598
GO:0005634	Component	Nucleus	IDA	12237128, 17303076
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0030154	Process	Cell differentiation	IEA
GO:0045892	Process	Negative regulation of DNA-templated transcription	IDA	12237128
GO:0046872	Function	Metal ion binding	IEA
GO:0046982	Function	Protein heterodimerization activity	IDA	12659632, 12741956

MIM	HGNC	e!Ensembl
604764	12871	ENSG00000165156

Q9UKY1

Protein name

Zinc fingers and homeoboxes protein 1

Protein function

Acts as a transcriptional repressor. Increases DNMT3B-mediated repressive transcriptional activity when DNMT3B is tethered to DNA. May link molecule between DNMT3B and other co-repressor proteins.

PDB

2ECB , 2GHF , 2LY9 , 3NAR

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00046	Homeodomain	665 → 717	Homeodomain	Domain
PF00046	Homeodomain	467 → 521	Homeodomain	Domain
PF00046	Homeodomain	573 → 623	Homeodomain	Domain
PF00046	Homeodomain	297 → 339	Homeodomain	Domain
PF11569	Homez	783 → 826	Homeodomain leucine-zipper encoding, Homez	Family
PF18387	zf_C2H2_ZHX	98 → 150	Zinc-fingers and homeoboxes C2H2 finger domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed. Expressed in podocytes. {ECO:0000269|PubMed:10441475, ECO:0000269|PubMed:17056598}.

Sequence

MASRRKSTTPCMVLASEQDPDLELISDLDEGPPVLTPVENTRAESISSDEEVHESVDSDN
QQNKKVEGGYECKYCTFQTPDLNMFTFHVDSEHPNVVLNSSYVCVECNFLTKRYDALSEH
NLKYHPGEENFKLTMVKRNNQTIFEQTINDLTFDGSFVKEENAEQAESTEVSSSGISISK
TPIMKMMKNKVENKRIAVHHNSVEDVPEEKENEIKPDREEIVENPSSSASESNTSTSIVN
RIHPSTASTVVTPAAVLPGLAQVITAVSAQQNSNLIPKVLIPVNSIPTYNAALDNNPLLL
NTYNKFPYPTMSEITVLSAQAKYTEEQIKIWFSAQRLKHGVSWTPEEVEEARRKQFNGTV
HTVPQTITVIPTHISTGSNGLPSILQTCQIVGQPGLVLTQVAGTNTLPVTAPIALTVAGV
PSQNNIQKSQVPAAQPTAETKPATAAVPTSQSVKHETALVNPDSFGIRAKKTKEQLAELK
VSYLKNQFPHDSEIIRLMKITGLTKGEIKKWFSDTRYNQRNSKSNQCLHLNNDSSTTIII
DSSDETTESPTVGTAQPKQSWNPFPDFTPQKFKEKTAEQLRVLQASFLNSSVLTDEELNR
LRAQTKLTRREIDAWFTEKKKSKALKEEKMEIDESNAGSSKEEAGETSPADESGAPKSGS
TGKICKKTPEQLHMLKSAFVRTQWPSPEEYDKLAKESGLARTDIVSWFGDTRYAWKNGNL
KWYYYYQSANSSSMNGLSSLRKRGRGRPKGRGRGRPRGRPRGSKRINNWDRGPSLIKFKT
GTAILKDYYLKHKFLNEQDLDELVNKSHMGYEQVREWFAERQRRSELGIELFEENEEEDE
VIDDQEEDEEETDDSDTWEPPRHVKRKLSKSDD

Sequence length

873

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
EBV-positive nodal T- and NK-cell lymphoma	Likely benign	ClinVar	—	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining Show/Hide Text Mining Associations (27)
Adult Hodgkin Lymphoma	Hodgkin Lymphoma	BEFREE	26406991		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	27835650		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	27835650	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	28351300	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	27835650	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	28152006	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
cervical cancer	Cervical Cancer	BEFREE	30231238		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cervix carcinoma	Cervix carcinoma	BEFREE	30231238		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cholangiocarcinoma	Cholangiocarcinoma	BEFREE	27835650		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cholangiocarcinoma	Cholangiocarcinoma	Pubtator	27835650	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Clear-cell metastatic renal cell carcinoma	Renal Carcinoma	BEFREE	28152006		★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital contractural arachnodactyly	Congenital Contractural Arachnodactyly	BEFREE	27835650		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	28351300, 31648104		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	28351300	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	28351300, 31648104		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin disease	Pubtator	26406991	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin Disease	BEFREE	26406991		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	24064680, 27835650		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	27835650		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	25448600		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	24064680		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of cervix	Cervical Tumor	BEFREE	30231238		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	25448600		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	25448600		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	25448600	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	27835650	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	30231238	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

Related Genes Genes most often co-reported with ZHX1 across shared curated disease and pathway associations. 0 Download as csv Download as pdf
No strongly related genes found yet for ZHX1.

Diseases Linked via Similar Genes Diseases curated for genes most similar to ZHX1 (see Related Genes above), that are NOT already directly curated for ZHX1 itself -- a lead worth checking, not a confirmed association. 0 Download as csv Download as pdf
No additional diseases found yet through genes similar to ZHX1.

ZHX1 (zinc fingers and homeoboxes 1)

Bookmark This Gene