ZG16B (zymogen granule protein 16B)

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Gene miRNA Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 124220
• Gene name: Zymogen granule protein 16B
• Gene symbol: ZG16B
• Synonyms (NCBI Gene): EECP, HRPE773, JCLN2, PAUF, PRO1567
• Chromosome: 16
• Chromosome location: 16p13.3

miRNA Show/Hide all (25)

miRTarBase ID	miRNA	Experiments	Reference
MIRT019177	hsa-miR-335-5p	Microarray	18185580
MIRT1512870	hsa-miR-3145-5p	CLIP-seq
MIRT1512871	hsa-miR-3165	CLIP-seq
MIRT1512872	hsa-miR-3925-3p	CLIP-seq
MIRT1512873	hsa-miR-3942-3p	CLIP-seq
MIRT1512874	hsa-miR-4320	CLIP-seq
MIRT1512875	hsa-miR-4712-5p	CLIP-seq
MIRT1512876	hsa-miR-508-5p	CLIP-seq
MIRT1512877	hsa-miR-770-5p	CLIP-seq
MIRT1512878	hsa-miR-935	CLIP-seq
MIRT1512870	hsa-miR-3145-5p	CLIP-seq
MIRT1512872	hsa-miR-3925-3p	CLIP-seq
MIRT1512875	hsa-miR-4712-5p	CLIP-seq
MIRT1512876	hsa-miR-508-5p	CLIP-seq
MIRT1512877	hsa-miR-770-5p	CLIP-seq
MIRT1512878	hsa-miR-935	CLIP-seq
MIRT2374664	hsa-miR-1912	CLIP-seq
MIRT2374665	hsa-miR-3157-5p	CLIP-seq
MIRT1512871	hsa-miR-3165	CLIP-seq
MIRT2374666	hsa-miR-3189-5p	CLIP-seq
MIRT1512873	hsa-miR-3942-3p	CLIP-seq
MIRT1512874	hsa-miR-4320	CLIP-seq
MIRT2374667	hsa-miR-4691-3p	CLIP-seq
MIRT2374668	hsa-miR-4757-5p	CLIP-seq
MIRT1512878	hsa-miR-935	CLIP-seq

Gene ontology (GO) Show/Hide all (15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	20802527, 25416956, 32296183, 36232715
GO:0005576	Component	Extracellular region	IDA	19302292
GO:0005576	Component	Extracellular region	IEA
GO:0005615	Component	Extracellular space	HDA	16502470, 22664934, 23580065
GO:0005615	Component	Extracellular space	IBA
GO:0005737	Component	Cytoplasm	IDA	19302292
GO:0005737	Component	Cytoplasm	IEA
GO:0005886	Component	Plasma membrane	IDA	36232715
GO:0005886	Component	Plasma membrane	IEA
GO:0016020	Component	Membrane	IEA
GO:0016327	Component	Apicolateral plasma membrane	IDA	19302292
GO:0016327	Component	Apicolateral plasma membrane	IEA
GO:0016477	Process	Cell migration	IDA	19302292, 36232715
GO:0030246	Function	Carbohydrate binding	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867, 19199708, 23533145

Other IDs

• MIM: 620477
• HGNC: 30456
• e!Ensembl: ENSG00000162078

Protein

• UniProt ID: Q96DA0
• Protein name: Pancreatic adenocarcinoma up-regulated factor (Zymogen granule protein 16 homolog B)
• Protein function: Plays an important role in pancreatic tumor progression and metastasis (PubMed:19302292, PubMed:36232715). Promotes pancreatic cancer cells migration and invasion through the TLR4/MyD88/NF-kaapaB signaling pathway, without the involvement of the
• PDB: 3AQG
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01419	Jacalin	77 → 185	Jacalin-like lectin domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Highly expressed in pancreatic cancer tissues (at protein levels). Also expressed in the placenta and colon and ovarian cancer tumors. {ECO:0000269|PubMed:19302292}.
• Sequence:

  MGAQGAQESIKAMWRVPGTTRRPVTGESPGMHRPEAMLLLLTLALLGGPTWAGKMYGPGG
  GKYFSTTEDYDHEITGLRVSVGLLLVKSVQVKLGDSWDVKLGALGGNTQEVTLQPGEYIT
  KVFVAFQAFLRGMVMYTSKDRYFYFGKLDGQISSAYPSQEGQVLVGIYGQYQLLGIKSIG
  FEWNYPLEEPTTEPPVNLTYSANSPVGR

• Sequence length: 208

Related Genes

No strongly related genes found yet for ZG16B.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZG16B.