Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	50626
Gene name	Zinc finger TRAF-type containing 1
Gene symbol	ZFTRAF1
Synonyms (NCBI Gene)	CHRPCYHR1
Chromosome	8
Chromosome location	8q24.3

48 Show/Hide all (48)

miRTarBase ID	miRNA	Experiments
MIRT920213	hsa-miR-3153	CLIP-seq
MIRT920214	hsa-miR-3665	CLIP-seq
MIRT920215	hsa-miR-3689a-3p	CLIP-seq
MIRT920216	hsa-miR-3689c	CLIP-seq
MIRT920217	hsa-miR-4514	CLIP-seq
MIRT920218	hsa-miR-4690-5p	CLIP-seq
MIRT920219	hsa-miR-4692	CLIP-seq
MIRT920220	hsa-miR-4728-5p	CLIP-seq
MIRT920221	hsa-miR-4736	CLIP-seq
MIRT920222	hsa-miR-940	CLIP-seq
MIRT920213	hsa-miR-3153	CLIP-seq
MIRT920214	hsa-miR-3665	CLIP-seq
MIRT920215	hsa-miR-3689a-3p	CLIP-seq
MIRT920216	hsa-miR-3689c	CLIP-seq
MIRT920223	hsa-miR-4255	CLIP-seq
MIRT920217	hsa-miR-4514	CLIP-seq
MIRT920218	hsa-miR-4690-5p	CLIP-seq
MIRT920219	hsa-miR-4692	CLIP-seq
MIRT920220	hsa-miR-4728-5p	CLIP-seq
MIRT920221	hsa-miR-4736	CLIP-seq
MIRT920222	hsa-miR-940	CLIP-seq
MIRT920224	hsa-miR-1207-5p	CLIP-seq
MIRT920225	hsa-miR-1827	CLIP-seq
MIRT920226	hsa-miR-1909	CLIP-seq
MIRT920227	hsa-miR-3173-3p	CLIP-seq
MIRT920228	hsa-miR-3612	CLIP-seq
MIRT920229	hsa-miR-3922-5p	CLIP-seq
MIRT920230	hsa-miR-4492	CLIP-seq
MIRT920231	hsa-miR-4498	CLIP-seq
MIRT920232	hsa-miR-4505	CLIP-seq
MIRT920233	hsa-miR-4533	CLIP-seq
MIRT920234	hsa-miR-4731-5p	CLIP-seq
MIRT920235	hsa-miR-4763-3p	CLIP-seq
MIRT920236	hsa-miR-4779	CLIP-seq
MIRT920237	hsa-miR-4787-5p	CLIP-seq
MIRT920238	hsa-miR-486-3p	CLIP-seq
MIRT920239	hsa-miR-550a	CLIP-seq
MIRT920240	hsa-miR-650	CLIP-seq
MIRT920241	hsa-miR-762	CLIP-seq
MIRT920222	hsa-miR-940	CLIP-seq
MIRT2512250	hsa-miR-3921	CLIP-seq
MIRT2512251	hsa-miR-4303	CLIP-seq
MIRT2512252	hsa-miR-4508	CLIP-seq
MIRT2512253	hsa-miR-4653-5p	CLIP-seq
MIRT2512254	hsa-miR-4715-3p	CLIP-seq
MIRT2512255	hsa-miR-548q	CLIP-seq
MIRT2512256	hsa-miR-566	CLIP-seq
MIRT2512257	hsa-miR-593	CLIP-seq

7 Show/Hide all (7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	28514442, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005635	Component	Nuclear envelope	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA

MIM	HGNC	e!Ensembl
616635	17806	ENSG00000187954

Protein Protein information from UniProt database. Download as csv Download as pdf
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.	P0DTL6
Protein name	Zinc finger TRAF-type-containing protein 1 (Cysteine and histidine-rich protein 1)
Family and domains
Sequence
Sequence length
Interactions	View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Neurodevelopmental disorder with hypotonia and gross motor and speech delay	Pathogenic; Likely pathogenic	rs2537530774, rs2537521774, rs2537521414	RCV003331459 RCV003331460 RCV003332419	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal. Show/Hide Unknown Diseases (7)
ALZHEIMER DISEASE	—	GWAS catalog	34743297	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autosomal recessive non-syndromic intellectual disability	Uncertain significance	ClinVar Disgenet	—	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
COMPLEX NEURODEVELOPMENTAL DISORDER	—	GenCC	—	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEURODEVELOPMENTAL DISORDER	—	GWAS catalog	38641995	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEURODEVELOPMENTAL DISORDERS	—	Disgenet	38641995	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-SPECIFIC SYNDROMIC INTELLECTUAL DISABILITY	—	Disgenet	—	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	31374203	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Disease Name	Disease (Merged)	Source	PMID	Evidence Score
Associations from Text Mining Disease associations identified through text mining Show/Hide Text Mining Associations (7)
Esophageal carcinoma	Esophageal Carcinoma	BEFREE	26676980	★★★★★ ★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Esophagus Neoplasm	BEFREE	26676980	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of esophagus	Esophagus Neoplasm	BEFREE	26676980	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	26676980	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	26676980	★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	GWASCAT_DG	31374203	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	26676980	★★★★★ ★☆☆☆☆ Found in Text Mining only

ZFTRAF1 (zinc finger TRAF-type containing 1)

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