ZFP69B (ZFP69 zinc finger protein B)

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Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases Diseases linked via similar genes

Gene

• Entrez ID: 65243
• Gene name: ZFP69 zinc finger protein B
• Gene symbol: ZFP69B
• Synonyms (NCBI Gene): ZKSCAN23B, ZNF643, ZSCAN54B
• Chromosome: 1
• Chromosome location: 1p34.2

miRNA Show/Hide all (234)

miRTarBase ID	miRNA	Experiments	Reference
MIRT665275	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT665274	hsa-miR-6854-5p	HITS-CLIP	23824327
MIRT665273	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT665272	hsa-miR-764	HITS-CLIP	23824327
MIRT665271	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT665270	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT665269	hsa-miR-4267	HITS-CLIP	23824327
MIRT561268	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT665268	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT665267	hsa-miR-4252	HITS-CLIP	23824327
MIRT665266	hsa-miR-3934-3p	HITS-CLIP	23824327
MIRT665265	hsa-miR-7703	HITS-CLIP	23824327
MIRT561271	hsa-miR-329-5p	PAR-CLIP	20371350
MIRT561270	hsa-miR-4712-5p	PAR-CLIP	20371350
MIRT561269	hsa-miR-770-5p	PAR-CLIP	20371350
MIRT561268	hsa-miR-766-3p	PAR-CLIP	20371350
MIRT561266	hsa-miR-3925-3p	PAR-CLIP	20371350
MIRT561267	hsa-miR-515-5p	PAR-CLIP	20371350
MIRT561265	hsa-miR-519e-5p	PAR-CLIP	20371350
MIRT519850	hsa-miR-181b-5p	PAR-CLIP	20371350
MIRT519849	hsa-miR-181c-5p	PAR-CLIP	20371350
MIRT519847	hsa-miR-4262	PAR-CLIP	20371350
MIRT519848	hsa-miR-181d-5p	PAR-CLIP	20371350
MIRT519846	hsa-miR-181a-5p	PAR-CLIP	20371350
MIRT519845	hsa-miR-376b-3p	PAR-CLIP	20371350
MIRT519844	hsa-miR-376a-3p	PAR-CLIP	20371350
MIRT519842	hsa-miR-5571-5p	PAR-CLIP	20371350
MIRT519843	hsa-miR-1226-3p	PAR-CLIP	20371350
MIRT519841	hsa-miR-4733-3p	PAR-CLIP	20371350
MIRT519839	hsa-miR-6511a-3p	PAR-CLIP	20371350
MIRT519838	hsa-miR-6511b-3p	PAR-CLIP	20371350
MIRT519837	hsa-miR-6784-3p	PAR-CLIP	20371350
MIRT519836	hsa-miR-6862-3p	PAR-CLIP	20371350
MIRT519835	hsa-miR-146a-3p	PAR-CLIP	20371350
MIRT519834	hsa-miR-301a-5p	PAR-CLIP	20371350
MIRT519833	hsa-miR-301b-5p	PAR-CLIP	20371350
MIRT519832	hsa-miR-3921	PAR-CLIP	20371350
MIRT519831	hsa-miR-4653-5p	PAR-CLIP	20371350
MIRT519830	hsa-miR-1229-3p	PAR-CLIP	20371350
MIRT519829	hsa-miR-3191-5p	PAR-CLIP	20371350
MIRT561271	hsa-miR-329-5p	PAR-CLIP	20371350
MIRT561270	hsa-miR-4712-5p	PAR-CLIP	20371350
MIRT561269	hsa-miR-770-5p	PAR-CLIP	20371350
MIRT561268	hsa-miR-766-3p	PAR-CLIP	20371350
MIRT561266	hsa-miR-3925-3p	PAR-CLIP	20371350
MIRT564764	hsa-miR-4502	PAR-CLIP	20371350
MIRT561267	hsa-miR-515-5p	PAR-CLIP	20371350
MIRT561265	hsa-miR-519e-5p	PAR-CLIP	20371350
MIRT561271	hsa-miR-329-5p	PAR-CLIP	20371350
MIRT561270	hsa-miR-4712-5p	PAR-CLIP	20371350
MIRT561269	hsa-miR-770-5p	PAR-CLIP	20371350
MIRT561268	hsa-miR-766-3p	PAR-CLIP	20371350
MIRT561266	hsa-miR-3925-3p	PAR-CLIP	20371350
MIRT561267	hsa-miR-515-5p	PAR-CLIP	20371350
MIRT561265	hsa-miR-519e-5p	PAR-CLIP	20371350
MIRT532995	hsa-miR-580-5p	PAR-CLIP	21572407
MIRT532995	hsa-miR-580-5p	PAR-CLIP	22012620
MIRT519850	hsa-miR-181b-5p	PAR-CLIP	23446348
MIRT519849	hsa-miR-181c-5p	PAR-CLIP	23446348
MIRT519847	hsa-miR-4262	PAR-CLIP	23446348
MIRT519848	hsa-miR-181d-5p	PAR-CLIP	23446348
MIRT519846	hsa-miR-181a-5p	PAR-CLIP	23446348
MIRT519845	hsa-miR-376b-3p	PAR-CLIP	23446348
MIRT519844	hsa-miR-376a-3p	PAR-CLIP	23446348
MIRT519842	hsa-miR-5571-5p	PAR-CLIP	23446348
MIRT519843	hsa-miR-1226-3p	PAR-CLIP	23446348
MIRT519841	hsa-miR-4733-3p	PAR-CLIP	23446348
MIRT519840	hsa-miR-483-3p	PAR-CLIP	23446348
MIRT519839	hsa-miR-6511a-3p	PAR-CLIP	23446348
MIRT519838	hsa-miR-6511b-3p	PAR-CLIP	23446348
MIRT519837	hsa-miR-6784-3p	PAR-CLIP	23446348
MIRT519836	hsa-miR-6862-3p	PAR-CLIP	23446348
MIRT519835	hsa-miR-146a-3p	PAR-CLIP	23446348
MIRT519834	hsa-miR-301a-5p	PAR-CLIP	23446348
MIRT519833	hsa-miR-301b-5p	PAR-CLIP	23446348
MIRT519832	hsa-miR-3921	PAR-CLIP	23446348
MIRT519831	hsa-miR-4653-5p	PAR-CLIP	23446348
MIRT519830	hsa-miR-1229-3p	PAR-CLIP	23446348
MIRT519829	hsa-miR-3191-5p	PAR-CLIP	23446348
MIRT452563	hsa-miR-124-3p	PAR-CLIP	23592263
MIRT452589	hsa-miR-3714	PAR-CLIP	23592263
MIRT452588	hsa-miR-3910	PAR-CLIP	23592263
MIRT452587	hsa-miR-302f	PAR-CLIP	23592263
MIRT452586	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT452585	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT452584	hsa-miR-940	PAR-CLIP	23592263
MIRT452583	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT452582	hsa-miR-3192-5p	PAR-CLIP	23592263
MIRT452581	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT452580	hsa-miR-2114-3p	PAR-CLIP	23592263
MIRT452579	hsa-miR-6823-3p	PAR-CLIP	23592263
MIRT452578	hsa-miR-6134	PAR-CLIP	23592263
MIRT452577	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT452576	hsa-miR-6086	PAR-CLIP	23592263
MIRT452575	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT452574	hsa-miR-661	PAR-CLIP	23592263
MIRT452573	hsa-miR-3689d	PAR-CLIP	23592263
MIRT452572	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT452571	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT452570	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT452569	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT452568	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT452567	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT452566	hsa-miR-6799-5p	PAR-CLIP	23592263
MIRT452565	hsa-miR-6880-5p	PAR-CLIP	23592263
MIRT452564	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT452563	hsa-miR-124-3p	PAR-CLIP	23592263
MIRT452562	hsa-miR-506-3p	PAR-CLIP	23592263
MIRT452561	hsa-miR-6807-5p	PAR-CLIP	23592263
MIRT452560	hsa-miR-1273e	PAR-CLIP	23592263
MIRT452559	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT452558	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT452557	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT452556	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT452555	hsa-miR-3689c	PAR-CLIP	23592263
MIRT452554	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT452553	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT665275	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT665274	hsa-miR-6854-5p	HITS-CLIP	23824327
MIRT665273	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT665272	hsa-miR-764	HITS-CLIP	23824327
MIRT665271	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT665270	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT665269	hsa-miR-4267	HITS-CLIP	23824327
MIRT561268	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT665268	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT665267	hsa-miR-4252	HITS-CLIP	23824327
MIRT665266	hsa-miR-3934-3p	HITS-CLIP	23824327
MIRT665265	hsa-miR-7703	HITS-CLIP	23824327
MIRT561271	hsa-miR-329-5p	PAR-CLIP	20371350
MIRT561270	hsa-miR-4712-5p	PAR-CLIP	20371350
MIRT561269	hsa-miR-770-5p	PAR-CLIP	20371350
MIRT561268	hsa-miR-766-3p	PAR-CLIP	20371350
MIRT561266	hsa-miR-3925-3p	PAR-CLIP	20371350
MIRT561267	hsa-miR-515-5p	PAR-CLIP	20371350
MIRT561265	hsa-miR-519e-5p	PAR-CLIP	20371350
MIRT519850	hsa-miR-181b-5p	PAR-CLIP	20371350
MIRT519849	hsa-miR-181c-5p	PAR-CLIP	20371350
MIRT519847	hsa-miR-4262	PAR-CLIP	20371350
MIRT519848	hsa-miR-181d-5p	PAR-CLIP	20371350
MIRT519846	hsa-miR-181a-5p	PAR-CLIP	20371350
MIRT519845	hsa-miR-376b-3p	PAR-CLIP	20371350
MIRT519844	hsa-miR-376a-3p	PAR-CLIP	20371350
MIRT519842	hsa-miR-5571-5p	PAR-CLIP	20371350
MIRT519843	hsa-miR-1226-3p	PAR-CLIP	20371350
MIRT519841	hsa-miR-4733-3p	PAR-CLIP	20371350
MIRT519839	hsa-miR-6511a-3p	PAR-CLIP	20371350
MIRT519838	hsa-miR-6511b-3p	PAR-CLIP	20371350
MIRT519837	hsa-miR-6784-3p	PAR-CLIP	20371350
MIRT519836	hsa-miR-6862-3p	PAR-CLIP	20371350
MIRT519835	hsa-miR-146a-3p	PAR-CLIP	20371350
MIRT519834	hsa-miR-301a-5p	PAR-CLIP	20371350
MIRT519833	hsa-miR-301b-5p	PAR-CLIP	20371350
MIRT519832	hsa-miR-3921	PAR-CLIP	20371350
MIRT519831	hsa-miR-4653-5p	PAR-CLIP	20371350
MIRT519830	hsa-miR-1229-3p	PAR-CLIP	20371350
MIRT519829	hsa-miR-3191-5p	PAR-CLIP	20371350
MIRT561271	hsa-miR-329-5p	PAR-CLIP	20371350
MIRT561270	hsa-miR-4712-5p	PAR-CLIP	20371350
MIRT561269	hsa-miR-770-5p	PAR-CLIP	20371350
MIRT561268	hsa-miR-766-3p	PAR-CLIP	20371350
MIRT561266	hsa-miR-3925-3p	PAR-CLIP	20371350
MIRT564764	hsa-miR-4502	PAR-CLIP	20371350
MIRT561267	hsa-miR-515-5p	PAR-CLIP	20371350
MIRT561265	hsa-miR-519e-5p	PAR-CLIP	20371350
MIRT561271	hsa-miR-329-5p	PAR-CLIP	20371350
MIRT561270	hsa-miR-4712-5p	PAR-CLIP	20371350
MIRT561269	hsa-miR-770-5p	PAR-CLIP	20371350
MIRT561268	hsa-miR-766-3p	PAR-CLIP	20371350
MIRT561266	hsa-miR-3925-3p	PAR-CLIP	20371350
MIRT561267	hsa-miR-515-5p	PAR-CLIP	20371350
MIRT561265	hsa-miR-519e-5p	PAR-CLIP	20371350
MIRT532995	hsa-miR-580-5p	PAR-CLIP	21572407
MIRT532995	hsa-miR-580-5p	PAR-CLIP	22012620
MIRT519850	hsa-miR-181b-5p	PAR-CLIP	23446348
MIRT519849	hsa-miR-181c-5p	PAR-CLIP	23446348
MIRT519847	hsa-miR-4262	PAR-CLIP	23446348
MIRT519848	hsa-miR-181d-5p	PAR-CLIP	23446348
MIRT519846	hsa-miR-181a-5p	PAR-CLIP	23446348
MIRT519845	hsa-miR-376b-3p	PAR-CLIP	23446348
MIRT519844	hsa-miR-376a-3p	PAR-CLIP	23446348
MIRT519842	hsa-miR-5571-5p	PAR-CLIP	23446348
MIRT519843	hsa-miR-1226-3p	PAR-CLIP	23446348
MIRT519841	hsa-miR-4733-3p	PAR-CLIP	23446348
MIRT519840	hsa-miR-483-3p	PAR-CLIP	23446348
MIRT519839	hsa-miR-6511a-3p	PAR-CLIP	23446348
MIRT519838	hsa-miR-6511b-3p	PAR-CLIP	23446348
MIRT519837	hsa-miR-6784-3p	PAR-CLIP	23446348
MIRT519836	hsa-miR-6862-3p	PAR-CLIP	23446348
MIRT519835	hsa-miR-146a-3p	PAR-CLIP	23446348
MIRT519834	hsa-miR-301a-5p	PAR-CLIP	23446348
MIRT519833	hsa-miR-301b-5p	PAR-CLIP	23446348
MIRT519832	hsa-miR-3921	PAR-CLIP	23446348
MIRT519831	hsa-miR-4653-5p	PAR-CLIP	23446348
MIRT519830	hsa-miR-1229-3p	PAR-CLIP	23446348
MIRT519829	hsa-miR-3191-5p	PAR-CLIP	23446348
MIRT452563	hsa-miR-124-3p	PAR-CLIP	23592263
MIRT452589	hsa-miR-3714	PAR-CLIP	23592263
MIRT452588	hsa-miR-3910	PAR-CLIP	23592263
MIRT452587	hsa-miR-302f	PAR-CLIP	23592263
MIRT452586	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT452585	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT452584	hsa-miR-940	PAR-CLIP	23592263
MIRT452583	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT452582	hsa-miR-3192-5p	PAR-CLIP	23592263
MIRT452581	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT452580	hsa-miR-2114-3p	PAR-CLIP	23592263
MIRT452579	hsa-miR-6823-3p	PAR-CLIP	23592263
MIRT452578	hsa-miR-6134	PAR-CLIP	23592263
MIRT452577	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT452576	hsa-miR-6086	PAR-CLIP	23592263
MIRT452575	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT452574	hsa-miR-661	PAR-CLIP	23592263
MIRT452573	hsa-miR-3689d	PAR-CLIP	23592263
MIRT452572	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT452571	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT452570	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT452569	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT452568	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT452567	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT452566	hsa-miR-6799-5p	PAR-CLIP	23592263
MIRT452565	hsa-miR-6880-5p	PAR-CLIP	23592263
MIRT452564	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT452563	hsa-miR-124-3p	PAR-CLIP	23592263
MIRT452562	hsa-miR-506-3p	PAR-CLIP	23592263
MIRT452561	hsa-miR-6807-5p	PAR-CLIP	23592263
MIRT452560	hsa-miR-1273e	PAR-CLIP	23592263
MIRT452559	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT452558	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT452557	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT452556	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT452555	hsa-miR-3689c	PAR-CLIP	23592263
MIRT452554	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT452553	hsa-miR-6780a-5p	PAR-CLIP	23592263

Gene ontology (GO) Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	29851555
GO:0005634	Component	Nucleus	IEA
GO:0005730	Component	Nucleolus	IDA	29851555
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0007030	Process	Golgi organization	IMP	29851555
GO:0008270	Function	Zinc ion binding	IEA
GO:0031981	Component	Nuclear lumen	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q9UJL9
• Protein name: Zinc finger protein 69 homolog B (Zinc finger protein 643)
• Protein function: May be involved in transcriptional regulation. Essential for Golgi structural integrity (PubMed:29851555).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	335 → 357	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	447 → 469	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	279 → 301	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	307 → 329	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	419 → 441	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	475 → 497	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	363 → 385	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	391 → 413	Zinc finger, C2H2 type	Domain
  PF01352	KRAB	73 → 114	KRAB box	Family
  PF02023	SCAN	1 → 42	SCAN domain	Domain

• Sequence:

  MLQQLLITLPTEASTWVKLRHPKAATERVALWEDVTKMFKAEALLSQDADETQGESLESR
  VTLGSLTAESQELLTFKDVSVDFTQEEWGQLAPAHRNLYREVMLENYGNLVSVGCQLSKP
  GVISQLEKGEEPWLMERDISGVPSSDLKSKTKTKESALQNDISWEELHCGLMMERFTKGS
  SMYSTLGRISKCNKLESQQENQRMGKGQIPLMCKKTFTQERGQESNRFEKRINVKSEVMP
  GPIGLPRKRDRKYDTPGKRSRYNIDLVNHSRSYTKMKTFECNICEKIFKQLIHLTEHMRI
  HTGEKPFRCKECGKAFSQSSSLIPHQRIHTGEKPYECKECGKTFRHPSSLTQHVRIHTGE
  KPYECRVCEKAFSQSIGLIQHLRTHVREKPFTCKDCGKAFFQIRHLRQHEIIHTGVKPYI
  CNVCSKTFSHSTYLTQHQRTHTGERPYKCKECGKAFSQRIHLSIHQRVHTGVKPYECSHC
  GKAFRHDSSFAKHQRIHTGEKPYDCNECGKAFSCSSSLIRHCKTHLRNTFSNVV

• Sequence length: 534

Pathways

Reactome Pathway:

Generic Transcription Pathway

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Colorectal cancer	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (7)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Breast Carcinoma	Breast Carcinoma	BEFREE	30524945		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes mellitus	Pubtator	29084944	Associate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	30524945		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	16966434		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	21777376		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	29084944	Associate	★☆☆☆☆ Found in Text Mining only
Thyroid carcinoma	Thyroid Carcinoma	BEFREE	8816445		★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for ZFP69B.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZFP69B.