ZFP37 (ZFP37 zinc finger protein)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 7539
• Gene name: ZFP37 zinc finger protein
• Gene symbol: ZFP37
• Synonyms (NCBI Gene): ZNF906, zfp-37
• Chromosome: 9
• Chromosome location: 9q32
• Summary: This gene encodes a transcription factor that belongs to a large family of zinc finger proteins. A similar protein in mouse is thought to play a role in regulating the structures of the nucleolus and centromere in neurons. Alternate splicing results in mu

miRNA Show/Hide all (53)

miRTarBase ID	miRNA	Experiments	Reference
MIRT044388	hsa-miR-320a	CLASH	23622248
MIRT036645	hsa-miR-935	CLASH	23622248
MIRT550663	hsa-miR-338-5p	PAR-CLIP	21572407
MIRT550662	hsa-miR-383-5p	PAR-CLIP	21572407
MIRT550661	hsa-miR-5694	PAR-CLIP	21572407
MIRT550660	hsa-miR-1244	PAR-CLIP	21572407
MIRT550659	hsa-miR-5692b	PAR-CLIP	21572407
MIRT550658	hsa-miR-5692c	PAR-CLIP	21572407
MIRT550657	hsa-miR-4729	PAR-CLIP	21572407
MIRT550656	hsa-miR-374a-5p	PAR-CLIP	21572407
MIRT550655	hsa-miR-374b-5p	PAR-CLIP	21572407
MIRT550654	hsa-miR-5696	PAR-CLIP	21572407
MIRT550653	hsa-miR-6869-5p	PAR-CLIP	21572407
MIRT445649	hsa-miR-590-3p	PAR-CLIP	22100165
MIRT445648	hsa-miR-380-3p	PAR-CLIP	22100165
MIRT445647	hsa-miR-4775	PAR-CLIP	22100165
MIRT445649	hsa-miR-590-3p	PAR-CLIP	22100165
MIRT445648	hsa-miR-380-3p	PAR-CLIP	22100165
MIRT445647	hsa-miR-4775	PAR-CLIP	22100165
MIRT550663	hsa-miR-338-5p	PAR-CLIP	21572407
MIRT550662	hsa-miR-383-5p	PAR-CLIP	21572407
MIRT550661	hsa-miR-5694	PAR-CLIP	21572407
MIRT550660	hsa-miR-1244	PAR-CLIP	21572407
MIRT550659	hsa-miR-5692b	PAR-CLIP	21572407
MIRT550658	hsa-miR-5692c	PAR-CLIP	21572407
MIRT550657	hsa-miR-4729	PAR-CLIP	21572407
MIRT550656	hsa-miR-374a-5p	PAR-CLIP	21572407
MIRT550655	hsa-miR-374b-5p	PAR-CLIP	21572407
MIRT550654	hsa-miR-5696	PAR-CLIP	21572407
MIRT550653	hsa-miR-6869-5p	PAR-CLIP	21572407
MIRT445649	hsa-miR-590-3p	PAR-CLIP	22100165
MIRT445648	hsa-miR-380-3p	PAR-CLIP	22100165
MIRT445647	hsa-miR-4775	PAR-CLIP	22100165
MIRT445649	hsa-miR-590-3p	PAR-CLIP	22100165
MIRT445648	hsa-miR-380-3p	PAR-CLIP	22100165
MIRT445647	hsa-miR-4775	PAR-CLIP	22100165
MIRT1511507	hsa-miR-3065-5p	CLIP-seq
MIRT1511508	hsa-miR-3668	CLIP-seq
MIRT1511509	hsa-miR-3935	CLIP-seq
MIRT1511510	hsa-miR-421	CLIP-seq
MIRT1511511	hsa-miR-4539	CLIP-seq
MIRT1511512	hsa-miR-4731-3p	CLIP-seq
MIRT1511513	hsa-miR-4801	CLIP-seq
MIRT1511514	hsa-miR-495	CLIP-seq
MIRT1511515	hsa-miR-513a-3p	CLIP-seq
MIRT1921109	hsa-miR-1207-3p	CLIP-seq
MIRT1921110	hsa-miR-3149	CLIP-seq
MIRT1921111	hsa-miR-3713	CLIP-seq
MIRT1921109	hsa-miR-1207-3p	CLIP-seq
MIRT1921110	hsa-miR-3149	CLIP-seq
MIRT1921111	hsa-miR-3713	CLIP-seq
MIRT2153964	hsa-miR-1305	CLIP-seq
MIRT1921110	hsa-miR-3149	CLIP-seq

Gene ontology (GO) Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	NAS	9585434
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	NAS	9585434
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0008270	Function	Zinc ion binding	NAS	9585434
GO:0045892	Process	Negative regulation of DNA-templated transcription	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 602951
• HGNC: 12863
• e!Ensembl: ENSG00000136866

Protein

• UniProt ID: Q9Y6Q3
• Protein name: Zinc finger protein 37 homolog (Zfp-37)
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	433 → 455	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	545 → 567	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	321 → 343	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	461 → 483	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	601 → 623	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	405 → 427	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	489 → 511	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	377 → 399	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	573 → 595	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	517 → 539	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	293 → 315	Zinc finger, C2H2 type	Domain
  PF01352	KRAB	41 → 72	KRAB box	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed at low level in several tissues including fetal cartilage.
• Sequence:

  MSVSSGVQILTKPETVDRRRSAETTKEAGRPLEMAVSEPEASAAEWKQLDPAQSNLYNDV
  MLENYCNQASMGCQAPKPDMISKLEKGEAPWLGKGKRPSQGCPSKIARPKQKETDGKVQK
  DDDQLENIQKSQNKLLREVAVKKKTQAKKNGSDCGSLGKKNNLHKKHVPSKKRLLKFESC
  GKILKQNLDLPDHSRNCVKRKSDAAKEHKKSFNHSLSDTRKGKKQTGKKHEKLSSHSSSD
  KCNKTGKKHDKLCCHSSSHIKQDKIQTGEKHEKSPSLSSSTKHEKPQACVKPYECNQCGK
  VLSHKQGLIDHQRVHTGEKPYECNECGIAFSQKSHLVVHQRTHTGEKPYECIQCGKAHGH
  KHALTDHLRIHTGEKPYECAECGKTFRHSSNLIQHVRSHTGEKPYECKECGKSFRYNSSL
  TEHVRTHTGEIPYECNECGKAFKYSSSLTKHMRIHTGEKPFECNECGKAFSKKSHLIIHQ
  RTHTKEKPYKCNECGKAFGHSSSLTYHMRTHTGESPFECNQCGKGFKQIEGLTQHQRVHT
  GEKPYECNECGKAFSQKSHLIVHQRTHTGEKPYECNECEKAFNAKSQLVIHQRSHTGEKP
  YECNECGKTFKQNASLTKHVKTHSEDKSHE

• Sequence length: 630

Pathways

Reactome Pathway:

Generic Transcription Pathway

Related Genes

No strongly related genes found yet for ZFP37.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZFP37.