ZFP28 (ZFP28 zinc finger protein)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 140612
• Gene name: ZFP28 zinc finger protein
• Gene symbol: ZFP28
• Synonyms (NCBI Gene): mkr5
• Chromosome: 19
• Chromosome location: 19q13.43

miRNA Show/Hide all (89)

miRTarBase ID	miRNA	Experiments	Reference
MIRT017361	hsa-miR-335-5p	Microarray	18185580
MIRT294283	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT294285	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT294284	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT294286	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT294287	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT294288	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT294292	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT294290	hsa-miR-3159	PAR-CLIP	20371350
MIRT294291	hsa-miR-5002-5p	PAR-CLIP	20371350
MIRT294289	hsa-miR-922	PAR-CLIP	20371350
MIRT560941	hsa-miR-133a-3p	PAR-CLIP	20371350
MIRT560941	hsa-miR-133a-3p	PAR-CLIP	20371350
MIRT560940	hsa-miR-133b	PAR-CLIP	20371350
MIRT294283	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT294285	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT294284	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT294286	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT294287	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT294288	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT294292	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT294290	hsa-miR-3159	PAR-CLIP	20371350
MIRT294291	hsa-miR-5002-5p	PAR-CLIP	20371350
MIRT294289	hsa-miR-922	PAR-CLIP	20371350
MIRT560941	hsa-miR-133a-3p	PAR-CLIP	20371350
MIRT560941	hsa-miR-133a-3p	PAR-CLIP	20371350
MIRT560940	hsa-miR-133b	PAR-CLIP	20371350
MIRT1510617	hsa-miR-1200	CLIP-seq
MIRT1510618	hsa-miR-1243	CLIP-seq
MIRT1510619	hsa-miR-1273g	CLIP-seq
MIRT1510620	hsa-miR-3161	CLIP-seq
MIRT1510621	hsa-miR-340	CLIP-seq
MIRT1510622	hsa-miR-3619-3p	CLIP-seq
MIRT1510623	hsa-miR-3654	CLIP-seq
MIRT1510624	hsa-miR-3663-3p	CLIP-seq
MIRT1510625	hsa-miR-4301	CLIP-seq
MIRT1510626	hsa-miR-4326	CLIP-seq
MIRT1510627	hsa-miR-4434	CLIP-seq
MIRT1510628	hsa-miR-4516	CLIP-seq
MIRT1510629	hsa-miR-4531	CLIP-seq
MIRT1510630	hsa-miR-4652-3p	CLIP-seq
MIRT1510631	hsa-miR-4687-3p	CLIP-seq
MIRT1510632	hsa-miR-4776-5p	CLIP-seq
MIRT1510633	hsa-miR-4778-5p	CLIP-seq
MIRT1510634	hsa-miR-548a-3p	CLIP-seq
MIRT1510635	hsa-miR-548e	CLIP-seq
MIRT1510636	hsa-miR-548f	CLIP-seq
MIRT1510622	hsa-miR-3619-3p	CLIP-seq
MIRT2153886	hsa-miR-3620	CLIP-seq
MIRT1510624	hsa-miR-3663-3p	CLIP-seq
MIRT1510630	hsa-miR-4652-3p	CLIP-seq
MIRT1510632	hsa-miR-4776-5p	CLIP-seq
MIRT2374114	hsa-miR-1287	CLIP-seq
MIRT2374115	hsa-miR-1323	CLIP-seq
MIRT2374116	hsa-miR-3135b	CLIP-seq
MIRT1510624	hsa-miR-3663-3p	CLIP-seq
MIRT2374117	hsa-miR-377	CLIP-seq
MIRT2374118	hsa-miR-4663	CLIP-seq
MIRT2374119	hsa-miR-4690-5p	CLIP-seq
MIRT2374120	hsa-miR-4699-3p	CLIP-seq
MIRT2374121	hsa-miR-4757-3p	CLIP-seq
MIRT2374122	hsa-miR-548g	CLIP-seq
MIRT2374123	hsa-miR-548o	CLIP-seq
MIRT2374124	hsa-miR-767-3p	CLIP-seq
MIRT2397351	hsa-miR-221	CLIP-seq
MIRT2397352	hsa-miR-222	CLIP-seq
MIRT2397353	hsa-miR-548v	CLIP-seq
MIRT2463913	hsa-miR-1207-5p	CLIP-seq
MIRT2463914	hsa-miR-4270	CLIP-seq
MIRT2463915	hsa-miR-4436b-3p	CLIP-seq
MIRT2463916	hsa-miR-4441	CLIP-seq
MIRT2463917	hsa-miR-4763-3p	CLIP-seq
MIRT2463918	hsa-miR-570	CLIP-seq
MIRT2666642	hsa-miR-2681	CLIP-seq
MIRT2666643	hsa-miR-4777-5p	CLIP-seq
MIRT2666644	hsa-miR-490-5p	CLIP-seq
MIRT2666645	hsa-miR-518d-5p	CLIP-seq
MIRT2666646	hsa-miR-519b-5p	CLIP-seq
MIRT2666647	hsa-miR-519c-5p	CLIP-seq
MIRT2666648	hsa-miR-520c-5p	CLIP-seq
MIRT2666649	hsa-miR-526a	CLIP-seq
MIRT2666642	hsa-miR-2681	CLIP-seq
MIRT2666643	hsa-miR-4777-5p	CLIP-seq
MIRT2666644	hsa-miR-490-5p	CLIP-seq
MIRT2666645	hsa-miR-518d-5p	CLIP-seq
MIRT2666646	hsa-miR-519b-5p	CLIP-seq
MIRT2666647	hsa-miR-519c-5p	CLIP-seq
MIRT2666648	hsa-miR-520c-5p	CLIP-seq
MIRT2666649	hsa-miR-526a	CLIP-seq

Gene ontology (GO) Show/Hide all (9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 616798
• HGNC: 17801
• e!Ensembl: ENSG00000196867

Protein

• UniProt ID: Q8NHY6
• Protein name: Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6)
• Protein function: May be involved in transcriptional regulation. May have a role in embryonic development.
• PDB: 2EM2 , 2EM3 , 2EM4 , 2EMJ , 2EMK , 2EML , 2EN9 , 2ENH , 2EOH , 2EP0 , 2EPX , 2EPZ , 2YTM
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	420 → 442	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	673 → 695	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	589 → 611	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	645 → 667	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	757 → 779	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	617 → 639	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	533 → 555	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	561 → 583	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	448 → 470	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	785 → 807	Zinc finger, C2H2 type	Domain
  PF01352	KRAB	102 → 143	KRAB box	Family
  PF01352	KRAB	231 → 268	KRAB box	Family
  PF13912	zf-C2H2_6	729 → 754		Domain

• Sequence:

  MRGAASASVREPTPLPGRGAPRTKPRAGRGPTVGTPATLALPARGRPRSRNGLASKGQRG
  AAPTGPGHRALPSRDTALPQERNKKLEAVGTGIEPKAMSQGLVTFGDVAVDFSQEEWEWL
  NPIQRNLYRKVMLENYRNLASLGLCVSKPDVISSLEQGKEPWTVKRKMTRAWCPDLKAVW
  KIKELPLKKDFCEGKLSQAVITERLTSYNLEYSLLGEHWDYDALFETQPGLVTIKNLAVD
  FRQQLHPAQKNFCKNGIWENNSDLGSAGHCVAKPDLVSLLEQEKEPWMVKRELTGSLFSG
  QRSVHETQELFPKQDSYAEGVTDRTSNTKLDCSSFRENWDSDYVFGRKLAVGQETQFRQE
  PITHNKTLSKERERTYNKSGRWFYLDDSEEKVHNRDSIKNFQKSSVVIKQTGIYAGKKLF
  KCNECKKTFTQSSSLTVHQRIHTGEKPYKCNECGKAFSDGSSFARHQRCHTGKKPYECIE
  CGKAFIQNTSLIRHWRYYHTGEKPFDCIDCGKAFSDHIGLNQHRRIHTGEKPYKCDVCHK
  SFRYGSSLTVHQRIHTGEKPYECDVCRKAFSHHASLTQHQRVHSGEKPFKCKECGKAFRQ
  NIHLASHLRIHTGEKPFECAECGKSFSISSQLATHQRIHTGEKPYECKVCSKAFTQKAHL
  AQHQKTHTGEKPYECKECGKAFSQTTHLIQHQRVHTGEKPYKCMECGKAFGDNSSCTQHQ
  RLHTGQRPYECIECGKAFKTKSSLICHRRSHTGEKPYECSVCGKAFSHRQSLSVHQRIHS
  GKKPYECKECRKTFIQIGHLNQHKRVHTGERSYNYKKSRKVFRQTAHLAHHQRIHTGESS
  TCPSLPSTSNPVDLFPKFLWNPSSLPSP

• Sequence length: 868

Pathways

Reactome Pathway:

Generic Transcription Pathway

Related Genes

No strongly related genes found yet for ZFP28.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZFP28.