ZBTB2 (zinc finger and BTB domain containing 2)

Download as csv Download as pdf

Log in to bookmark this gene

Bookmark This Gene

Title Project / Tag (optional) Note (optional)

Cancel Save

On this page

Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 57621
• Gene name: Zinc finger and BTB domain containing 2
• Gene symbol: ZBTB2
• Synonyms (NCBI Gene): ZNF437
• Chromosome: 6
• Chromosome location: 6q25.1

miRNA Show/Hide all (239)

miRTarBase ID	miRNA	Experiments	Reference
MIRT023138	hsa-miR-124-3p	Proteomics;Microarray	18668037
MIRT051258	hsa-miR-16-5p	CLASH	23622248
MIRT053498	hsa-miR-149-5p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	23144691
MIRT053498	hsa-miR-149-5p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	23144691
MIRT1502108	hsa-miR-153	CLIP-seq
MIRT1502109	hsa-miR-181a	CLIP-seq
MIRT1502110	hsa-miR-181b	CLIP-seq
MIRT1502111	hsa-miR-181c	CLIP-seq
MIRT1502112	hsa-miR-181d	CLIP-seq
MIRT1502113	hsa-miR-216a	CLIP-seq
MIRT1502114	hsa-miR-216b	CLIP-seq
MIRT1502115	hsa-miR-3120-3p	CLIP-seq
MIRT1502116	hsa-miR-34c-3p	CLIP-seq
MIRT1502117	hsa-miR-3591-5p	CLIP-seq
MIRT1502118	hsa-miR-3605-5p	CLIP-seq
MIRT1502119	hsa-miR-3617	CLIP-seq
MIRT1502120	hsa-miR-3671	CLIP-seq
MIRT1502121	hsa-miR-371-5p	CLIP-seq
MIRT1502122	hsa-miR-371b-5p	CLIP-seq
MIRT1502123	hsa-miR-4254	CLIP-seq
MIRT1502124	hsa-miR-4262	CLIP-seq
MIRT1502125	hsa-miR-4280	CLIP-seq
MIRT1502126	hsa-miR-4310	CLIP-seq
MIRT1502127	hsa-miR-448	CLIP-seq
MIRT1502128	hsa-miR-4511	CLIP-seq
MIRT1502129	hsa-miR-451b	CLIP-seq
MIRT1502130	hsa-miR-4766-3p	CLIP-seq
MIRT1502131	hsa-miR-4797-5p	CLIP-seq
MIRT1502132	hsa-miR-548b-3p	CLIP-seq
MIRT1502133	hsa-miR-548n	CLIP-seq
MIRT1502134	hsa-miR-548t	CLIP-seq
MIRT1502135	hsa-miR-586	CLIP-seq
MIRT1502136	hsa-miR-607	CLIP-seq
MIRT1502137	hsa-miR-619	CLIP-seq
MIRT1502138	hsa-miR-641	CLIP-seq
MIRT1502139	hsa-miR-765	CLIP-seq
MIRT1502140	hsa-miR-888	CLIP-seq
MIRT2150940	hsa-miR-1248	CLIP-seq
MIRT2150941	hsa-miR-1253	CLIP-seq
MIRT2150942	hsa-miR-1294	CLIP-seq
MIRT1502108	hsa-miR-153	CLIP-seq
MIRT2150943	hsa-miR-15a	CLIP-seq
MIRT2150944	hsa-miR-15b	CLIP-seq
MIRT2150945	hsa-miR-16	CLIP-seq
MIRT2150946	hsa-miR-1910	CLIP-seq
MIRT2150947	hsa-miR-1912	CLIP-seq
MIRT2150948	hsa-miR-1915	CLIP-seq
MIRT2150949	hsa-miR-195	CLIP-seq
MIRT2150950	hsa-miR-2052	CLIP-seq
MIRT2150951	hsa-miR-2355-5p	CLIP-seq
MIRT1502115	hsa-miR-3120-3p	CLIP-seq
MIRT2150952	hsa-miR-3130-5p	CLIP-seq
MIRT2150953	hsa-miR-3149	CLIP-seq
MIRT2150954	hsa-miR-3190	CLIP-seq
MIRT2150955	hsa-miR-3616-5p	CLIP-seq
MIRT2150956	hsa-miR-3647-5p	CLIP-seq
MIRT2150957	hsa-miR-3660	CLIP-seq
MIRT2150958	hsa-miR-3679-3p	CLIP-seq
MIRT2150959	hsa-miR-3682-5p	CLIP-seq
MIRT2150960	hsa-miR-374a	CLIP-seq
MIRT2150961	hsa-miR-374b	CLIP-seq
MIRT2150962	hsa-miR-424	CLIP-seq
MIRT2150963	hsa-miR-4251	CLIP-seq
MIRT2150964	hsa-miR-4256	CLIP-seq
MIRT2150965	hsa-miR-4263	CLIP-seq
MIRT2150966	hsa-miR-4286	CLIP-seq
MIRT2150967	hsa-miR-4303	CLIP-seq
MIRT2150968	hsa-miR-431	CLIP-seq
MIRT1502126	hsa-miR-4310	CLIP-seq
MIRT2150969	hsa-miR-4316	CLIP-seq
MIRT2150970	hsa-miR-4329	CLIP-seq
MIRT1502127	hsa-miR-448	CLIP-seq
MIRT2150971	hsa-miR-4482	CLIP-seq
MIRT2150972	hsa-miR-4491	CLIP-seq
MIRT2150973	hsa-miR-450b-5p	CLIP-seq
MIRT2150974	hsa-miR-4526	CLIP-seq
MIRT2150975	hsa-miR-455-3p	CLIP-seq
MIRT2150976	hsa-miR-4657	CLIP-seq
MIRT2150977	hsa-miR-4659a-5p	CLIP-seq
MIRT2150978	hsa-miR-4659b-5p	CLIP-seq
MIRT2150979	hsa-miR-4670-3p	CLIP-seq
MIRT2150980	hsa-miR-4704-3p	CLIP-seq
MIRT2150981	hsa-miR-4729	CLIP-seq
MIRT2150982	hsa-miR-4762-3p	CLIP-seq
MIRT2150983	hsa-miR-4764-5p	CLIP-seq
MIRT2150984	hsa-miR-4776-3p	CLIP-seq
MIRT2150985	hsa-miR-4777-5p	CLIP-seq
MIRT1502131	hsa-miR-4797-5p	CLIP-seq
MIRT2150986	hsa-miR-497	CLIP-seq
MIRT2150987	hsa-miR-507	CLIP-seq
MIRT2150988	hsa-miR-511	CLIP-seq
MIRT2150989	hsa-miR-518d-5p	CLIP-seq
MIRT2150990	hsa-miR-519b-5p	CLIP-seq
MIRT2150991	hsa-miR-519c-5p	CLIP-seq
MIRT2150992	hsa-miR-520c-5p	CLIP-seq
MIRT2150993	hsa-miR-526a	CLIP-seq
MIRT2150994	hsa-miR-557	CLIP-seq
MIRT2150995	hsa-miR-561	CLIP-seq
MIRT2150996	hsa-miR-573	CLIP-seq
MIRT2150997	hsa-miR-581	CLIP-seq
MIRT2150998	hsa-miR-616	CLIP-seq
MIRT2150999	hsa-miR-629	CLIP-seq
MIRT2150940	hsa-miR-1248	CLIP-seq
MIRT2150941	hsa-miR-1253	CLIP-seq
MIRT2371571	hsa-miR-1265	CLIP-seq
MIRT2150942	hsa-miR-1294	CLIP-seq
MIRT2371572	hsa-miR-149	CLIP-seq
MIRT2150943	hsa-miR-15a	CLIP-seq
MIRT2150944	hsa-miR-15b	CLIP-seq
MIRT2150945	hsa-miR-16	CLIP-seq
MIRT1502109	hsa-miR-181a	CLIP-seq
MIRT1502110	hsa-miR-181b	CLIP-seq
MIRT1502111	hsa-miR-181c	CLIP-seq
MIRT1502112	hsa-miR-181d	CLIP-seq
MIRT2150946	hsa-miR-1910	CLIP-seq
MIRT2150949	hsa-miR-195	CLIP-seq
MIRT2371573	hsa-miR-205	CLIP-seq
MIRT2150950	hsa-miR-2052	CLIP-seq
MIRT2371574	hsa-miR-3064-5p	CLIP-seq
MIRT2371575	hsa-miR-3148	CLIP-seq
MIRT2371576	hsa-miR-3151	CLIP-seq
MIRT2150954	hsa-miR-3190	CLIP-seq
MIRT2150957	hsa-miR-3660	CLIP-seq
MIRT2150959	hsa-miR-3682-5p	CLIP-seq
MIRT2371577	hsa-miR-3691-3p	CLIP-seq
MIRT2150960	hsa-miR-374a	CLIP-seq
MIRT2150961	hsa-miR-374b	CLIP-seq
MIRT2150962	hsa-miR-424	CLIP-seq
MIRT2150964	hsa-miR-4256	CLIP-seq
MIRT2371578	hsa-miR-4257	CLIP-seq
MIRT1502124	hsa-miR-4262	CLIP-seq
MIRT2150965	hsa-miR-4263	CLIP-seq
MIRT2371579	hsa-miR-4283	CLIP-seq
MIRT2150968	hsa-miR-431	CLIP-seq
MIRT2150969	hsa-miR-4316	CLIP-seq
MIRT2371580	hsa-miR-4434	CLIP-seq
MIRT2371581	hsa-miR-4489	CLIP-seq
MIRT2150972	hsa-miR-4491	CLIP-seq
MIRT2371582	hsa-miR-4492	CLIP-seq
MIRT2371583	hsa-miR-4498	CLIP-seq
MIRT2371584	hsa-miR-4505	CLIP-seq
MIRT2371585	hsa-miR-4516	CLIP-seq
MIRT1502129	hsa-miR-451b	CLIP-seq
MIRT2150974	hsa-miR-4526	CLIP-seq
MIRT2150975	hsa-miR-455-3p	CLIP-seq
MIRT2150976	hsa-miR-4657	CLIP-seq
MIRT2150982	hsa-miR-4762-3p	CLIP-seq
MIRT2150983	hsa-miR-4764-5p	CLIP-seq
MIRT1502130	hsa-miR-4766-3p	CLIP-seq
MIRT2150985	hsa-miR-4777-5p	CLIP-seq
MIRT2371586	hsa-miR-4794	CLIP-seq
MIRT1502131	hsa-miR-4797-5p	CLIP-seq
MIRT2150986	hsa-miR-497	CLIP-seq
MIRT2150988	hsa-miR-511	CLIP-seq
MIRT2150989	hsa-miR-518d-5p	CLIP-seq
MIRT2150990	hsa-miR-519b-5p	CLIP-seq
MIRT2150991	hsa-miR-519c-5p	CLIP-seq
MIRT2150992	hsa-miR-520c-5p	CLIP-seq
MIRT2150993	hsa-miR-526a	CLIP-seq
MIRT2371587	hsa-miR-576-5p	CLIP-seq
MIRT2150997	hsa-miR-581	CLIP-seq
MIRT2371588	hsa-miR-762	CLIP-seq
MIRT2150941	hsa-miR-1253	CLIP-seq
MIRT2150947	hsa-miR-1912	CLIP-seq
MIRT2150948	hsa-miR-1915	CLIP-seq
MIRT2150952	hsa-miR-3130-5p	CLIP-seq
MIRT2150963	hsa-miR-4251	CLIP-seq
MIRT2150967	hsa-miR-4303	CLIP-seq
MIRT2150970	hsa-miR-4329	CLIP-seq
MIRT2150971	hsa-miR-4482	CLIP-seq
MIRT1502129	hsa-miR-451b	CLIP-seq
MIRT2150982	hsa-miR-4762-3p	CLIP-seq
MIRT1502130	hsa-miR-4766-3p	CLIP-seq
MIRT2150941	hsa-miR-1253	CLIP-seq
MIRT2371571	hsa-miR-1265	CLIP-seq
MIRT2664861	hsa-miR-1284	CLIP-seq
MIRT2664862	hsa-miR-146a	CLIP-seq
MIRT2664863	hsa-miR-146b-5p	CLIP-seq
MIRT2150950	hsa-miR-2052	CLIP-seq
MIRT2664864	hsa-miR-2053	CLIP-seq
MIRT2664865	hsa-miR-2392	CLIP-seq
MIRT2664866	hsa-miR-23a	CLIP-seq
MIRT2664867	hsa-miR-23b	CLIP-seq
MIRT2664868	hsa-miR-23c	CLIP-seq
MIRT2664869	hsa-miR-3143	CLIP-seq
MIRT2371575	hsa-miR-3148	CLIP-seq
MIRT2664870	hsa-miR-3150b-3p	CLIP-seq
MIRT2150954	hsa-miR-3190	CLIP-seq
MIRT2664871	hsa-miR-3613-5p	CLIP-seq
MIRT2664872	hsa-miR-3682-3p	CLIP-seq
MIRT2664873	hsa-miR-4271	CLIP-seq
MIRT2664874	hsa-miR-4279	CLIP-seq
MIRT2664875	hsa-miR-4328	CLIP-seq
MIRT2371580	hsa-miR-4434	CLIP-seq
MIRT2664876	hsa-miR-4502	CLIP-seq
MIRT2371585	hsa-miR-4516	CLIP-seq
MIRT2150977	hsa-miR-4659a-5p	CLIP-seq
MIRT2150978	hsa-miR-4659b-5p	CLIP-seq
MIRT2664877	hsa-miR-4725-3p	CLIP-seq
MIRT2664878	hsa-miR-4753-3p	CLIP-seq
MIRT2664879	hsa-miR-4768-5p	CLIP-seq
MIRT2150984	hsa-miR-4776-3p	CLIP-seq
MIRT2664880	hsa-miR-4784	CLIP-seq
MIRT2664881	hsa-miR-4803	CLIP-seq
MIRT2664882	hsa-miR-520d-5p	CLIP-seq
MIRT2664883	hsa-miR-524-5p	CLIP-seq
MIRT2664884	hsa-miR-548a-5p	CLIP-seq
MIRT2664885	hsa-miR-548ab	CLIP-seq
MIRT2664886	hsa-miR-548ak	CLIP-seq
MIRT2664887	hsa-miR-548b-5p	CLIP-seq
MIRT2664888	hsa-miR-548c-5p	CLIP-seq
MIRT2664889	hsa-miR-548d-5p	CLIP-seq
MIRT2664890	hsa-miR-548h	CLIP-seq
MIRT2664891	hsa-miR-548i	CLIP-seq
MIRT2664892	hsa-miR-548j	CLIP-seq
MIRT2664893	hsa-miR-548k	CLIP-seq
MIRT2664894	hsa-miR-548l	CLIP-seq
MIRT2664895	hsa-miR-548w	CLIP-seq
MIRT2664896	hsa-miR-548y	CLIP-seq
MIRT2664897	hsa-miR-556-3p	CLIP-seq
MIRT2664898	hsa-miR-559	CLIP-seq
MIRT2664899	hsa-miR-580	CLIP-seq
MIRT2664900	hsa-miR-589	CLIP-seq
MIRT2150941	hsa-miR-1253	CLIP-seq
MIRT2664866	hsa-miR-23a	CLIP-seq
MIRT2664867	hsa-miR-23b	CLIP-seq
MIRT2664868	hsa-miR-23c	CLIP-seq
MIRT2371575	hsa-miR-3148	CLIP-seq
MIRT2664870	hsa-miR-3150b-3p	CLIP-seq
MIRT2150954	hsa-miR-3190	CLIP-seq
MIRT2664871	hsa-miR-3613-5p	CLIP-seq
MIRT2664873	hsa-miR-4271	CLIP-seq
MIRT2371580	hsa-miR-4434	CLIP-seq
MIRT2371585	hsa-miR-4516	CLIP-seq
MIRT2150977	hsa-miR-4659a-5p	CLIP-seq
MIRT2150978	hsa-miR-4659b-5p	CLIP-seq
MIRT2664877	hsa-miR-4725-3p	CLIP-seq
MIRT2150984	hsa-miR-4776-3p	CLIP-seq
MIRT2664880	hsa-miR-4784	CLIP-seq

Gene ontology (GO) Show/Hide all (16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IBA
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	19380588
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	25609694
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IBA
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	19380588
GO:0001817	Process	Regulation of cytokine production	IBA
GO:0002682	Process	Regulation of immune system process	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	25609694, 28514442, 32296183, 33961781, 35512704
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0042802	Function	Identical protein binding	IPI	32296183
GO:0046872	Function	Metal ion binding	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

Other IDs

• MIM: 616595
• HGNC: 20868
• e!Ensembl: ENSG00000181472

Protein

• UniProt ID: Q8N680
• Protein name: Zinc finger and BTB domain-containing protein 2
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	363 → 385	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	254 → 276	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	448 → 468	Zinc finger, C2H2 type	Domain
  PF00651	BTB	14 → 116	BTB/POZ domain	Domain

• Sequence:

  MDLANHGLILLQQLNAQREFGFLCDCTVAIGDVYFKAHKSVLASFSNYFKMLFVHQTSEC
  VRLKPTDIQPDIFSYLLHLMYTGKMAPQLIDPVRLEQGIKFLHAYPLIQEASLASQGAFS
  HPDQVFPLASSLYGIQIADHQLRQATKIASAPEKLGRDPRPQTSRISQEQVPEASQLSQL
  TSNLAQVNRTNMTPSDPLQTSLSPELVSTPVPPPPPGEETNLEASSSDEQPASLTIAHVK
  PSIMKRNGSFPKYYACHLCGRRFTLRSSLREHLQIHTGVPFTSSQQGESRVPLTLCSNAA
  DLGKDAMEVPEAGMISDSELQHISDSPIIDGQQQSETPPPSDIADIDNLEQADQEREVKR
  RKYECTICGRKFIQKSHWREHMYIHTGKPFKCSTCDKSFCRANQAARHVCLNQSIDTYTM
  VDKQTLELCTFEEGSQMDNMLVQTNKPYKCNLCDKTFSTPNEVVKHSCQNQNSDVFALDE
  GRSILLGSGDSEVTEPDHPVLASIKKEQETVLLD

• Sequence length: 514

Related Genes

No strongly related genes found yet for ZBTB2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ZBTB2.