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Gene Gene information from NCBI Gene database.
Entrez ID 84327
Gene name Zinc finger BED-type containing 3
Gene symbol ZBED3
Synonyms (NCBI Gene)
-
Chromosome 5
Chromosome location 5q13.3
Summary This gene belongs to a class of genes that arose through hAT DNA transposition and that encode regulatory proteins. This gene is upregulated in lung cancer tissues, where the encoded protein causes an accumulation of beta-catenin and enhanced lung cancer
miRNA miRNA information provided by mirtarbase database.
300 Show/Hide all (300)
miRTarBase ID miRNA Experiments Reference
MIRT002674 hsa-miR-124-3p Microarray 15685193
MIRT021400 hsa-miR-9-5p Sequencing 20371350
MIRT021400 hsa-miR-9-5p Microarray 17612493
MIRT002674 hsa-miR-124-3p Microarray 18668037
MIRT002674 hsa-miR-124-3p Microarray 15685193
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
34 Show/Hide all (34)
GO ID Ontology Definition Evidence Reference
GO:0000785 Component Chromatin ISA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific ISA
GO:0001933 Process Negative regulation of protein phosphorylation ISS
GO:0003677 Function DNA binding IEA
GO:0005576 Component Extracellular region IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
615250 20711 ENSG00000132846
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96IU2
Protein name Zinc finger BED domain-containing protein 3 (Axin-interacting protein)
Protein function Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by stabilizing cytoplasmic beta-catenin (By similarity). Involved in transcription activation of Wnt target gene expression (By similarity). Plays
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02892 zf-BED 46 → 98 BED zinc finger Domain
Tissue specificity TISSUE SPECIFICITY: Secreted in blood plasma, and expressed in skeletal muscle and adipose tissue (at protein level). {ECO:0000269|PubMed:24283382}.
Sequence
MRSGEPACTMDQARGLDDAAARGGQCPGLGPAPTPTPPGRLGAPYSEAWGYFHLAPGRPG
HPSGHWATCRLCGEQVGRGPGFHAGTSALWRHLRSAHR
RELESSGAGSSPPAAPCPPPPG
PAAAPEGDWARLLEQMGALAVRGSRRERELERRELAVEQGERALERRRRALQEEERAAAQ
ARRELQAEREALQARLRDVSRREGALGWAPAAPPPLKDDPEGDRDGCVITKVLL
Sequence length 234
Interactions View interactions