WWC2 (WW and C2 domain containing 2)

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Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 80014
• Gene name: WW and C2 domain containing 2
• Gene symbol: WWC2
• Synonyms (NCBI Gene): BOMB
• Chromosome: 4
• Chromosome location: 4q35.1
• Summary: This gene encodes a member of the WW-and-C2-domain-containing family of proteins. Members of this family have two N-terminal WW domains that mediate binding to target proteins harboring L/PPxY motifs, an internal C2 domain for membrane association, and C-

miRNA Show/Hide all (364)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020064	hsa-miR-375	Microarray	20215506
MIRT024576	hsa-miR-215-5p	Microarray	19074876
MIRT026951	hsa-miR-192-5p	Microarray	19074876
MIRT031068	hsa-miR-21-5p	Microarray	19253296
MIRT031068	hsa-miR-21-5p	Microarray	19342589
MIRT716839	hsa-miR-596	HITS-CLIP	19536157
MIRT716838	hsa-miR-4691-3p	HITS-CLIP	19536157
MIRT716837	hsa-miR-6849-3p	HITS-CLIP	19536157
MIRT716836	hsa-miR-766-3p	HITS-CLIP	19536157
MIRT716835	hsa-miR-3944-5p	HITS-CLIP	19536157
MIRT716834	hsa-miR-6512-3p	HITS-CLIP	19536157
MIRT716833	hsa-miR-6720-5p	HITS-CLIP	19536157
MIRT716832	hsa-miR-7156-3p	HITS-CLIP	19536157
MIRT636140	hsa-miR-3617-5p	HITS-CLIP	23824327
MIRT636139	hsa-miR-641	HITS-CLIP	23824327
MIRT665376	hsa-miR-3936	HITS-CLIP	23824327
MIRT665375	hsa-miR-615-5p	HITS-CLIP	23824327
MIRT636138	hsa-miR-208a-3p	HITS-CLIP	23824327
MIRT636137	hsa-miR-208b-3p	HITS-CLIP	23824327
MIRT636136	hsa-miR-499a-5p	HITS-CLIP	23824327
MIRT665374	hsa-miR-561-5p	HITS-CLIP	23824327
MIRT636135	hsa-miR-3658	HITS-CLIP	23824327
MIRT644052	hsa-miR-8485	HITS-CLIP	23824327
MIRT644051	hsa-miR-4699-3p	HITS-CLIP	23824327
MIRT644050	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT644049	hsa-miR-3121-5p	HITS-CLIP	23824327
MIRT644048	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT644047	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT644046	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT644045	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT644044	hsa-miR-664b-3p	HITS-CLIP	23824327
MIRT644043	hsa-miR-623	HITS-CLIP	23824327
MIRT644042	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT644041	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT644040	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT644039	hsa-miR-4774-3p	HITS-CLIP	23824327
MIRT644038	hsa-miR-3152-5p	HITS-CLIP	23824327
MIRT121334	hsa-miR-5584-3p	HITS-CLIP	23824327
MIRT636140	hsa-miR-3617-5p	HITS-CLIP	23824327
MIRT636139	hsa-miR-641	HITS-CLIP	23824327
MIRT636138	hsa-miR-208a-3p	HITS-CLIP	23824327
MIRT636137	hsa-miR-208b-3p	HITS-CLIP	23824327
MIRT636136	hsa-miR-499a-5p	HITS-CLIP	23824327
MIRT636135	hsa-miR-3658	HITS-CLIP	23824327
MIRT636134	hsa-miR-5004-3p	HITS-CLIP	23824327
MIRT636133	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT031068	hsa-miR-21-5p	Luciferase reporter assay, Western blotting, qRT-PCR	32623387
MIRT716839	hsa-miR-596	HITS-CLIP	19536157
MIRT716838	hsa-miR-4691-3p	HITS-CLIP	19536157
MIRT716837	hsa-miR-6849-3p	HITS-CLIP	19536157
MIRT716836	hsa-miR-766-3p	HITS-CLIP	19536157
MIRT716835	hsa-miR-3944-5p	HITS-CLIP	19536157
MIRT716834	hsa-miR-6512-3p	HITS-CLIP	19536157
MIRT716833	hsa-miR-6720-5p	HITS-CLIP	19536157
MIRT716832	hsa-miR-7156-3p	HITS-CLIP	19536157
MIRT636140	hsa-miR-3617-5p	HITS-CLIP	23824327
MIRT636139	hsa-miR-641	HITS-CLIP	23824327
MIRT665376	hsa-miR-3936	HITS-CLIP	23824327
MIRT665375	hsa-miR-615-5p	HITS-CLIP	23824327
MIRT636138	hsa-miR-208a-3p	HITS-CLIP	23824327
MIRT636137	hsa-miR-208b-3p	HITS-CLIP	23824327
MIRT636136	hsa-miR-499a-5p	HITS-CLIP	23824327
MIRT665374	hsa-miR-561-5p	HITS-CLIP	23824327
MIRT636135	hsa-miR-3658	HITS-CLIP	23824327
MIRT644052	hsa-miR-8485	HITS-CLIP	23824327
MIRT644051	hsa-miR-4699-3p	HITS-CLIP	23824327
MIRT644050	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT644049	hsa-miR-3121-5p	HITS-CLIP	23824327
MIRT644048	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT644047	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT644046	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT644045	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT644044	hsa-miR-664b-3p	HITS-CLIP	23824327
MIRT644043	hsa-miR-623	HITS-CLIP	23824327
MIRT644042	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT644041	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT644040	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT644039	hsa-miR-4774-3p	HITS-CLIP	23824327
MIRT644038	hsa-miR-3152-5p	HITS-CLIP	23824327
MIRT121334	hsa-miR-5584-3p	HITS-CLIP	23824327
MIRT636140	hsa-miR-3617-5p	HITS-CLIP	23824327
MIRT636139	hsa-miR-641	HITS-CLIP	23824327
MIRT636138	hsa-miR-208a-3p	HITS-CLIP	23824327
MIRT636137	hsa-miR-208b-3p	HITS-CLIP	23824327
MIRT636136	hsa-miR-499a-5p	HITS-CLIP	23824327
MIRT636135	hsa-miR-3658	HITS-CLIP	23824327
MIRT636134	hsa-miR-5004-3p	HITS-CLIP	23824327
MIRT636133	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT1494676	hsa-miR-106a	CLIP-seq
MIRT1494677	hsa-miR-106b	CLIP-seq
MIRT1494678	hsa-miR-10a	CLIP-seq
MIRT1494679	hsa-miR-10b	CLIP-seq
MIRT1494680	hsa-miR-1185	CLIP-seq
MIRT1494681	hsa-miR-1197	CLIP-seq
MIRT1494682	hsa-miR-1254	CLIP-seq
MIRT1494683	hsa-miR-1305	CLIP-seq
MIRT1494684	hsa-miR-137	CLIP-seq
MIRT1494685	hsa-miR-141	CLIP-seq
MIRT1494686	hsa-miR-17	CLIP-seq
MIRT1494687	hsa-miR-18a	CLIP-seq
MIRT1494688	hsa-miR-18b	CLIP-seq
MIRT1494689	hsa-miR-1914	CLIP-seq
MIRT1494690	hsa-miR-200a	CLIP-seq
MIRT1494691	hsa-miR-20a	CLIP-seq
MIRT1494692	hsa-miR-20b	CLIP-seq
MIRT1494693	hsa-miR-3116	CLIP-seq
MIRT1494694	hsa-miR-3155	CLIP-seq
MIRT1494695	hsa-miR-3155b	CLIP-seq
MIRT1494696	hsa-miR-3605-5p	CLIP-seq
MIRT1494697	hsa-miR-3609	CLIP-seq
MIRT1494698	hsa-miR-3653	CLIP-seq
MIRT1494699	hsa-miR-3679-5p	CLIP-seq
MIRT1494700	hsa-miR-3688-3p	CLIP-seq
MIRT1494701	hsa-miR-3714	CLIP-seq
MIRT1494702	hsa-miR-3929	CLIP-seq
MIRT1494703	hsa-miR-4419b	CLIP-seq
MIRT1494704	hsa-miR-4478	CLIP-seq
MIRT1494705	hsa-miR-4735-3p	CLIP-seq
MIRT1494706	hsa-miR-4761-5p	CLIP-seq
MIRT1494707	hsa-miR-4765	CLIP-seq
MIRT1494708	hsa-miR-4796-3p	CLIP-seq
MIRT1494709	hsa-miR-4799-5p	CLIP-seq
MIRT1494710	hsa-miR-484	CLIP-seq
MIRT1494711	hsa-miR-515-3p	CLIP-seq
MIRT1494712	hsa-miR-519d	CLIP-seq
MIRT1494713	hsa-miR-519e	CLIP-seq
MIRT1494714	hsa-miR-520d-5p	CLIP-seq
MIRT1494715	hsa-miR-524-5p	CLIP-seq
MIRT1494716	hsa-miR-548ah	CLIP-seq
MIRT1494717	hsa-miR-548an	CLIP-seq
MIRT1494718	hsa-miR-548g	CLIP-seq
MIRT1494719	hsa-miR-550a	CLIP-seq
MIRT1494720	hsa-miR-555	CLIP-seq
MIRT1494721	hsa-miR-607	CLIP-seq
MIRT1494722	hsa-miR-622	CLIP-seq
MIRT1494723	hsa-miR-628-5p	CLIP-seq
MIRT1494724	hsa-miR-642b	CLIP-seq
MIRT1494725	hsa-miR-661	CLIP-seq
MIRT1494726	hsa-miR-765	CLIP-seq
MIRT1494727	hsa-miR-93	CLIP-seq
MIRT1494689	hsa-miR-1914	CLIP-seq
MIRT2148978	hsa-miR-103a	CLIP-seq
MIRT2148979	hsa-miR-107	CLIP-seq
MIRT2148980	hsa-miR-1178	CLIP-seq
MIRT1494680	hsa-miR-1185	CLIP-seq
MIRT2148981	hsa-miR-1208	CLIP-seq
MIRT1494682	hsa-miR-1254	CLIP-seq
MIRT2148982	hsa-miR-1257	CLIP-seq
MIRT2148983	hsa-miR-1297	CLIP-seq
MIRT2148984	hsa-miR-130a	CLIP-seq
MIRT2148985	hsa-miR-130b	CLIP-seq
MIRT2148986	hsa-miR-153	CLIP-seq
MIRT1494687	hsa-miR-18a	CLIP-seq
MIRT1494688	hsa-miR-18b	CLIP-seq
MIRT2148987	hsa-miR-2052	CLIP-seq
MIRT2148988	hsa-miR-26a	CLIP-seq
MIRT2148989	hsa-miR-26b	CLIP-seq
MIRT2148990	hsa-miR-301a	CLIP-seq
MIRT2148991	hsa-miR-301b	CLIP-seq
MIRT1494693	hsa-miR-3116	CLIP-seq
MIRT2148992	hsa-miR-3149	CLIP-seq
MIRT2148993	hsa-miR-3163	CLIP-seq
MIRT2148994	hsa-miR-3171	CLIP-seq
MIRT2148995	hsa-miR-342-3p	CLIP-seq
MIRT1494696	hsa-miR-3605-5p	CLIP-seq
MIRT1494698	hsa-miR-3653	CLIP-seq
MIRT2148996	hsa-miR-3662	CLIP-seq
MIRT2148997	hsa-miR-3666	CLIP-seq
MIRT1494699	hsa-miR-3679-5p	CLIP-seq
MIRT2148998	hsa-miR-3680	CLIP-seq
MIRT2148999	hsa-miR-3940-5p	CLIP-seq
MIRT2149000	hsa-miR-411	CLIP-seq
MIRT2149001	hsa-miR-4268	CLIP-seq
MIRT2149002	hsa-miR-4293	CLIP-seq
MIRT2149003	hsa-miR-4295	CLIP-seq
MIRT2149004	hsa-miR-4307	CLIP-seq
MIRT2149005	hsa-miR-4329	CLIP-seq
MIRT2149006	hsa-miR-4446-5p	CLIP-seq
MIRT2149007	hsa-miR-4465	CLIP-seq
MIRT2149008	hsa-miR-4467	CLIP-seq
MIRT2149009	hsa-miR-448	CLIP-seq
MIRT2149010	hsa-miR-4502	CLIP-seq
MIRT2149011	hsa-miR-4507	CLIP-seq
MIRT2149012	hsa-miR-454	CLIP-seq
MIRT2149013	hsa-miR-4671-3p	CLIP-seq
MIRT2149014	hsa-miR-4704-5p	CLIP-seq
MIRT2149015	hsa-miR-4730	CLIP-seq
MIRT1494705	hsa-miR-4735-3p	CLIP-seq
MIRT2149016	hsa-miR-4738-5p	CLIP-seq
MIRT2149017	hsa-miR-4755-5p	CLIP-seq
MIRT2149018	hsa-miR-4769-3p	CLIP-seq
MIRT2149019	hsa-miR-4793-3p	CLIP-seq
MIRT2149020	hsa-miR-508-5p	CLIP-seq
MIRT1494711	hsa-miR-515-3p	CLIP-seq
MIRT1494713	hsa-miR-519e	CLIP-seq
MIRT1494714	hsa-miR-520d-5p	CLIP-seq
MIRT1494715	hsa-miR-524-5p	CLIP-seq
MIRT2149021	hsa-miR-548c-3p	CLIP-seq
MIRT2149022	hsa-miR-548p	CLIP-seq
MIRT1494719	hsa-miR-550a	CLIP-seq
MIRT1494720	hsa-miR-555	CLIP-seq
MIRT2149023	hsa-miR-579	CLIP-seq
MIRT2149024	hsa-miR-630	CLIP-seq
MIRT1494725	hsa-miR-661	CLIP-seq
MIRT2149025	hsa-miR-668	CLIP-seq
MIRT2149026	hsa-miR-766	CLIP-seq
MIRT2369463	hsa-miR-1179	CLIP-seq
MIRT2148981	hsa-miR-1208	CLIP-seq
MIRT2148982	hsa-miR-1257	CLIP-seq
MIRT1494683	hsa-miR-1305	CLIP-seq
MIRT1494685	hsa-miR-141	CLIP-seq
MIRT2369464	hsa-miR-149	CLIP-seq
MIRT2369465	hsa-miR-150	CLIP-seq
MIRT2148986	hsa-miR-153	CLIP-seq
MIRT2369466	hsa-miR-181a	CLIP-seq
MIRT2369467	hsa-miR-181b	CLIP-seq
MIRT2369468	hsa-miR-181c	CLIP-seq
MIRT2369469	hsa-miR-181d	CLIP-seq
MIRT2369470	hsa-miR-1915	CLIP-seq
MIRT1494690	hsa-miR-200a	CLIP-seq
MIRT2369471	hsa-miR-204	CLIP-seq
MIRT2148987	hsa-miR-2052	CLIP-seq
MIRT2369472	hsa-miR-208a	CLIP-seq
MIRT2369473	hsa-miR-208b	CLIP-seq
MIRT2369474	hsa-miR-211	CLIP-seq
MIRT2369475	hsa-miR-3064-5p	CLIP-seq
MIRT2369476	hsa-miR-3151	CLIP-seq
MIRT2148994	hsa-miR-3171	CLIP-seq
MIRT2369477	hsa-miR-3617	CLIP-seq
MIRT2148998	hsa-miR-3680	CLIP-seq
MIRT1494701	hsa-miR-3714	CLIP-seq
MIRT2369478	hsa-miR-3920	CLIP-seq
MIRT2148999	hsa-miR-3940-5p	CLIP-seq
MIRT2369479	hsa-miR-4262	CLIP-seq
MIRT2369480	hsa-miR-4269	CLIP-seq
MIRT2369481	hsa-miR-4303	CLIP-seq
MIRT2149004	hsa-miR-4307	CLIP-seq
MIRT2369482	hsa-miR-4428	CLIP-seq
MIRT2369483	hsa-miR-4434	CLIP-seq
MIRT2369484	hsa-miR-4447	CLIP-seq
MIRT2369485	hsa-miR-4468	CLIP-seq
MIRT2369486	hsa-miR-4472	CLIP-seq
MIRT2369487	hsa-miR-4477a	CLIP-seq
MIRT2149009	hsa-miR-448	CLIP-seq
MIRT2149011	hsa-miR-4507	CLIP-seq
MIRT2369488	hsa-miR-4516	CLIP-seq
MIRT2369489	hsa-miR-4645-5p	CLIP-seq
MIRT2369490	hsa-miR-4673	CLIP-seq
MIRT2369491	hsa-miR-4682	CLIP-seq
MIRT2369492	hsa-miR-4726-3p	CLIP-seq
MIRT2149017	hsa-miR-4755-5p	CLIP-seq
MIRT2369493	hsa-miR-4756-3p	CLIP-seq
MIRT2369494	hsa-miR-4762-3p	CLIP-seq
MIRT2149019	hsa-miR-4793-3p	CLIP-seq
MIRT2369495	hsa-miR-4794	CLIP-seq
MIRT2369496	hsa-miR-4798-3p	CLIP-seq
MIRT2369497	hsa-miR-490-3p	CLIP-seq
MIRT2369498	hsa-miR-491-5p	CLIP-seq
MIRT2369499	hsa-miR-499-5p	CLIP-seq
MIRT2369500	hsa-miR-513a-5p	CLIP-seq
MIRT1494714	hsa-miR-520d-5p	CLIP-seq
MIRT1494715	hsa-miR-524-5p	CLIP-seq
MIRT1494717	hsa-miR-548an	CLIP-seq
MIRT2149023	hsa-miR-579	CLIP-seq
MIRT2369501	hsa-miR-606	CLIP-seq
MIRT1494721	hsa-miR-607	CLIP-seq
MIRT2369502	hsa-miR-634	CLIP-seq
MIRT2369503	hsa-miR-635	CLIP-seq
MIRT2369504	hsa-miR-649	CLIP-seq
MIRT2149025	hsa-miR-668	CLIP-seq
MIRT2369505	hsa-miR-873	CLIP-seq
MIRT2397046	hsa-miR-3622a-5p	CLIP-seq
MIRT2397047	hsa-miR-3918	CLIP-seq
MIRT2397048	hsa-miR-4423-3p	CLIP-seq
MIRT2397049	hsa-miR-767-5p	CLIP-seq
MIRT2434857	hsa-miR-145	CLIP-seq
MIRT2434858	hsa-miR-198	CLIP-seq
MIRT2434859	hsa-miR-297	CLIP-seq
MIRT2148992	hsa-miR-3149	CLIP-seq
MIRT2434860	hsa-miR-380	CLIP-seq
MIRT2434861	hsa-miR-3942-5p	CLIP-seq
MIRT2434862	hsa-miR-4495	CLIP-seq
MIRT2434863	hsa-miR-4659a-5p	CLIP-seq
MIRT2434864	hsa-miR-4659b-5p	CLIP-seq
MIRT2434865	hsa-miR-4703-5p	CLIP-seq
MIRT2434866	hsa-miR-4775	CLIP-seq
MIRT2434867	hsa-miR-567	CLIP-seq
MIRT2434868	hsa-miR-654-3p	CLIP-seq
MIRT2148986	hsa-miR-153	CLIP-seq
MIRT2663063	hsa-miR-21	CLIP-seq
MIRT2148992	hsa-miR-3149	CLIP-seq
MIRT2663064	hsa-miR-3183	CLIP-seq
MIRT2148996	hsa-miR-3662	CLIP-seq
MIRT2148998	hsa-miR-3680	CLIP-seq
MIRT1494700	hsa-miR-3688-3p	CLIP-seq
MIRT2663065	hsa-miR-3978	CLIP-seq
MIRT2663066	hsa-miR-421	CLIP-seq
MIRT2149001	hsa-miR-4268	CLIP-seq
MIRT2663067	hsa-miR-4279	CLIP-seq
MIRT2149009	hsa-miR-448	CLIP-seq
MIRT2663068	hsa-miR-4684-3p	CLIP-seq
MIRT2663069	hsa-miR-4694-3p	CLIP-seq
MIRT2663070	hsa-miR-4709-5p	CLIP-seq
MIRT2663071	hsa-miR-4723-3p	CLIP-seq
MIRT2663072	hsa-miR-4738-3p	CLIP-seq
MIRT2149016	hsa-miR-4738-5p	CLIP-seq
MIRT2149018	hsa-miR-4769-3p	CLIP-seq
MIRT2369496	hsa-miR-4798-3p	CLIP-seq
MIRT2663073	hsa-miR-505	CLIP-seq
MIRT2663074	hsa-miR-518a-3p	CLIP-seq
MIRT2663075	hsa-miR-518b	CLIP-seq
MIRT2663076	hsa-miR-518c	CLIP-seq
MIRT2663077	hsa-miR-518d-3p	CLIP-seq
MIRT2663078	hsa-miR-518e	CLIP-seq
MIRT2663079	hsa-miR-518f	CLIP-seq
MIRT1494714	hsa-miR-520d-5p	CLIP-seq
MIRT1494715	hsa-miR-524-5p	CLIP-seq
MIRT2663080	hsa-miR-556-5p	CLIP-seq
MIRT2149023	hsa-miR-579	CLIP-seq
MIRT2663081	hsa-miR-590-5p	CLIP-seq
MIRT2663082	hsa-miR-767-3p	CLIP-seq
MIRT2695319	hsa-miR-138	CLIP-seq
MIRT2663063	hsa-miR-21	CLIP-seq
MIRT2695320	hsa-miR-2116	CLIP-seq
MIRT2148992	hsa-miR-3149	CLIP-seq
MIRT2663064	hsa-miR-3183	CLIP-seq
MIRT2695321	hsa-miR-3652	CLIP-seq
MIRT2695322	hsa-miR-3675-3p	CLIP-seq
MIRT2148998	hsa-miR-3680	CLIP-seq
MIRT1494700	hsa-miR-3688-3p	CLIP-seq
MIRT2663065	hsa-miR-3978	CLIP-seq
MIRT2149001	hsa-miR-4268	CLIP-seq
MIRT2663067	hsa-miR-4279	CLIP-seq
MIRT2695323	hsa-miR-4287	CLIP-seq
MIRT2695324	hsa-miR-4290	CLIP-seq
MIRT2695325	hsa-miR-4430	CLIP-seq
MIRT2695326	hsa-miR-4469	CLIP-seq
MIRT2695327	hsa-miR-4505	CLIP-seq
MIRT2695328	hsa-miR-4520a-5p	CLIP-seq
MIRT2695329	hsa-miR-4520b-5p	CLIP-seq
MIRT2695330	hsa-miR-4659a-3p	CLIP-seq
MIRT2695331	hsa-miR-4659b-3p	CLIP-seq
MIRT2695332	hsa-miR-4677-5p	CLIP-seq
MIRT2695333	hsa-miR-4685-3p	CLIP-seq
MIRT2663069	hsa-miR-4694-3p	CLIP-seq
MIRT2695334	hsa-miR-4694-5p	CLIP-seq
MIRT2695335	hsa-miR-4713-5p	CLIP-seq
MIRT2663071	hsa-miR-4723-3p	CLIP-seq
MIRT2149016	hsa-miR-4738-5p	CLIP-seq
MIRT2149018	hsa-miR-4769-3p	CLIP-seq
MIRT2369496	hsa-miR-4798-3p	CLIP-seq
MIRT2369500	hsa-miR-513a-5p	CLIP-seq
MIRT2663074	hsa-miR-518a-3p	CLIP-seq
MIRT2663075	hsa-miR-518b	CLIP-seq
MIRT2663076	hsa-miR-518c	CLIP-seq
MIRT2663077	hsa-miR-518d-3p	CLIP-seq
MIRT2663078	hsa-miR-518e	CLIP-seq
MIRT2663079	hsa-miR-518f	CLIP-seq
MIRT2663080	hsa-miR-556-5p	CLIP-seq
MIRT2149023	hsa-miR-579	CLIP-seq
MIRT2663081	hsa-miR-590-5p	CLIP-seq
MIRT2663082	hsa-miR-767-3p	CLIP-seq
MIRT2369505	hsa-miR-873	CLIP-seq
MIRT2695336	hsa-miR-942	CLIP-seq

Gene ontology (GO) Show/Hide all (27)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	24682284
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0005515	Function	Protein binding	IPI	15161933, 35271311
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	35429439
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA	24682284
GO:0005829	Component	Cytosol	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IBA
GO:0008285	Process	Negative regulation of cell population proliferation	IEA
GO:0008285	Process	Negative regulation of cell population proliferation	IMP	24682284
GO:0016477	Process	Cell migration	IBA
GO:0019900	Function	Kinase binding	IBA
GO:0019900	Function	Kinase binding	IPI	24682284
GO:0035329	Process	Hippo signaling	IDA	15688006, 18328708, 35429439
GO:0035329	Process	Hippo signaling	IDA	35429439
GO:0035329	Process	Hippo signaling	IEA
GO:0035330	Process	Regulation of hippo signaling	IBA
GO:0035331	Process	Negative regulation of hippo signaling	IDA	24682284
GO:0035331	Process	Negative regulation of hippo signaling	IEA
GO:0035591	Function	Signaling adaptor activity	IDA	35429439
GO:0035591	Function	Signaling adaptor activity	IEA
GO:0046621	Process	Negative regulation of organ growth	IBA
GO:0046621	Process	Negative regulation of organ growth	IEA
GO:0046621	Process	Negative regulation of organ growth	IMP	24682284
GO:0060090	Function	Molecular adaptor activity	IBA
GO:0060090	Function	Molecular adaptor activity	IDA	24682284

Other IDs

• MIM: 620110
• HGNC: 24148
• e!Ensembl: ENSG00000151718

Protein

• UniProt ID: Q6AWC2
• Protein name: Protein WWC2 (BH-3-only member B) (WW domain-containing protein 2)
• Protein function: Regulator of the Hippo signaling pathway, also known as the Salvador-Warts-Hippo (SWH) pathway. Enhances phosphorylation of LATS1 and YAP1 and negatively regulates cell proliferation and organ growth due to a suppression of the transcriptional a
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00397	WW	12 → 41	WW domain	Domain
  PF00397	WW	59 → 88	WW domain	Domain

• Sequence:

  MPRRAGSGQLPLPRGWEEARDYDGKVFYIDHNTRRTSWIDPRDRLTKPLSFADCVGDELP
  WGWEAGFDPQIGVYYIDHINKTTQIEDPRKQWRGEQEKMLKDYLSVAQDALRTQKELYHV
  KEQRLALALDEYVRLNDAYKEKSSSHTSLFSGSSSSTKYDPDILKAEISTTRLRVKKLKR
  ELSQMKQELLYKEQGFETLQQIDKKMSGGQSGYELSEAKAILTELKSIRKAISSGEKEKQ
  DLMQSLAKLQERFHLDQNIGRSEPDLRCSPVNSHLCLSRQTLDAGSQTSISGDIGVRSRS
  NLAEKVRLSLQYEEAKRSMANLKIELSKLDSEAWPGALDIEKEKLMLINEKEELLKELQF
  VTPQKRTQDELERLEAERQRLEEELLSVRGTPSRALAERLRLEERRKELLQKLEETTKLT
  TYLHSQLKSLSASTLSMSSGSSLGSLASSRGSLNTSSRGSLNSLSSTELYYSSQSDQIDV
  DYQYKLDFLLQEKSGYIPSGPITTIHENEVVKSPSQPGQSGLCGVAAAATGHTPPLAEAP
  KSVASLSSRSSLSSLSPPGSPLVLEGTFPMSSSHDASLHQFTADFEDCELSSHFADISLI
  ENQILLDSDSGGASQSLSEDKDLNECAREPLYEGTADVEKSLPKRRVIHLLGEKTTCVSA
  AVSDESVAGDSGVYEAFVKQPSEMEDVTYSEEDVAIVETAQVQIGLRYNAKSSSFMVIIA
  QLRNLHAFLIPHTSKVYFRVAVLPSSTDVSCLFRTKVHPPTESILFNDVFRVAISQTALQ
  QKTLRVDLCSVSKHRREECLAGTQISLADLPFSSEVFTLWYNLLPSKQMPCKKNEENEDS
  VFQPNQPLVDSIDLDAVSALLARTSAELLAVEQELAQEEEEESGQEEPRGPDGDWLTMLR
  EASDEIVAEKEAEVKLPEDSSCTEDLSSCTSVPEMNEDGNRKESNCAKDLRSQPPTRIPT
  LVDKETNTDEAANDNMAVRPKERSSLSSRQHPFVRSSVIVRSQTFSPGERNQYICRLNRS
  DSDSSTLAKKSLFVRNSTERRSLRVKRTVCQSVLRRTTQECPVRTSLDLELDLQASLTRQ
  SRLNDELQALRDLRQKLEELKAQGETDLPPGVLEDERFQRLLKQAEKQAEQSKEEQKQGL
  NAEKLMRQVSKDVCRLREQSQKVPRQVQSFREKIAYFTRAKISIPSLPADDV

• Sequence length: 1192

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Long QT syndrome	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (10)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	28815883	Inhibit	★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	31541369		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	35399646	Associate	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	29237971		★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	GWASCAT_DG	27903959		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	28815883		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	28815883		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	28815883		★☆☆☆☆ Found in Text Mining only
Pituitary Neoplasms	Pituitary neoplasm	Pubtator	37418994	Associate	★☆☆☆☆ Found in Text Mining only
Polycystic Ovary Syndrome	Polycystic ovary syndrome	Pubtator	33224973	Associate	★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for WWC2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to WWC2.