WBP4 (WW domain binding protein 4)

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Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 11193
• Gene name: WW domain binding protein 4
• Gene symbol: WBP4
• Synonyms (NCBI Gene): FBP21, NEDHFDB
• Chromosome: 13
• Chromosome location: 13q14.11
• Summary: This gene encodes WW domain-containing binding protein 4. The WW domain represents a small and compact globular structure that interacts with proline-rich ligands. This encoded protein is a general spliceosomal protein that may play a role in cross-intron

miRNA Show/Hide all (349)

miRTarBase ID	miRNA	Experiments	Reference
MIRT050577	hsa-miR-20a-5p	CLASH	23622248
MIRT405627	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT405626	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT405636	hsa-miR-548n	PAR-CLIP	20371350
MIRT405630	hsa-miR-548a-5p	PAR-CLIP	20371350
MIRT405643	hsa-miR-548ab	PAR-CLIP	20371350
MIRT405644	hsa-miR-548ad-5p	PAR-CLIP	20371350
MIRT405645	hsa-miR-548ae-5p	PAR-CLIP	20371350
MIRT405647	hsa-miR-548ak	PAR-CLIP	20371350
MIRT405648	hsa-miR-548am-5p	PAR-CLIP	20371350
MIRT405649	hsa-miR-548ap-5p	PAR-CLIP	20371350
MIRT405650	hsa-miR-548aq-5p	PAR-CLIP	20371350
MIRT405651	hsa-miR-548ar-5p	PAR-CLIP	20371350
MIRT405652	hsa-miR-548as-5p	PAR-CLIP	20371350
MIRT405653	hsa-miR-548au-5p	PAR-CLIP	20371350
MIRT405655	hsa-miR-548ay-5p	PAR-CLIP	20371350
MIRT405629	hsa-miR-548b-5p	PAR-CLIP	20371350
MIRT405656	hsa-miR-548bb-5p	PAR-CLIP	20371350
MIRT405631	hsa-miR-548c-5p	PAR-CLIP	20371350
MIRT405632	hsa-miR-548d-5p	PAR-CLIP	20371350
MIRT405637	hsa-miR-548h-5p	PAR-CLIP	20371350
MIRT405638	hsa-miR-548i	PAR-CLIP	20371350
MIRT405633	hsa-miR-548j-5p	PAR-CLIP	20371350
MIRT405642	hsa-miR-548o-5p	PAR-CLIP	20371350
MIRT405639	hsa-miR-548w	PAR-CLIP	20371350
MIRT405641	hsa-miR-548y	PAR-CLIP	20371350
MIRT405628	hsa-miR-559	PAR-CLIP	20371350
MIRT546026	hsa-miR-5700	PAR-CLIP	20371350
MIRT546025	hsa-miR-586	PAR-CLIP	20371350
MIRT405646	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT405634	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT405635	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT405640	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT546024	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT405654	hsa-miR-548aw	PAR-CLIP	20371350
MIRT546022	hsa-miR-548q	PAR-CLIP	20371350
MIRT405627	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT405626	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT405636	hsa-miR-548n	PAR-CLIP	20371350
MIRT405630	hsa-miR-548a-5p	PAR-CLIP	20371350
MIRT405643	hsa-miR-548ab	PAR-CLIP	20371350
MIRT405644	hsa-miR-548ad-5p	PAR-CLIP	20371350
MIRT405645	hsa-miR-548ae-5p	PAR-CLIP	20371350
MIRT405647	hsa-miR-548ak	PAR-CLIP	20371350
MIRT405648	hsa-miR-548am-5p	PAR-CLIP	20371350
MIRT405649	hsa-miR-548ap-5p	PAR-CLIP	20371350
MIRT405650	hsa-miR-548aq-5p	PAR-CLIP	20371350
MIRT405651	hsa-miR-548ar-5p	PAR-CLIP	20371350
MIRT405652	hsa-miR-548as-5p	PAR-CLIP	20371350
MIRT405653	hsa-miR-548au-5p	PAR-CLIP	20371350
MIRT405655	hsa-miR-548ay-5p	PAR-CLIP	20371350
MIRT405629	hsa-miR-548b-5p	PAR-CLIP	20371350
MIRT405656	hsa-miR-548bb-5p	PAR-CLIP	20371350
MIRT405631	hsa-miR-548c-5p	PAR-CLIP	20371350
MIRT405632	hsa-miR-548d-5p	PAR-CLIP	20371350
MIRT405637	hsa-miR-548h-5p	PAR-CLIP	20371350
MIRT405638	hsa-miR-548i	PAR-CLIP	20371350
MIRT405633	hsa-miR-548j-5p	PAR-CLIP	20371350
MIRT405642	hsa-miR-548o-5p	PAR-CLIP	20371350
MIRT405639	hsa-miR-548w	PAR-CLIP	20371350
MIRT405641	hsa-miR-548y	PAR-CLIP	20371350
MIRT405628	hsa-miR-559	PAR-CLIP	20371350
MIRT546026	hsa-miR-5700	PAR-CLIP	20371350
MIRT546025	hsa-miR-586	PAR-CLIP	20371350
MIRT405646	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT405634	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT405635	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT405640	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT546024	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT405654	hsa-miR-548aw	PAR-CLIP	20371350
MIRT546022	hsa-miR-548q	PAR-CLIP	20371350
MIRT405627	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT405626	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT405636	hsa-miR-548n	PAR-CLIP	20371350
MIRT405630	hsa-miR-548a-5p	PAR-CLIP	20371350
MIRT405643	hsa-miR-548ab	PAR-CLIP	20371350
MIRT405644	hsa-miR-548ad-5p	PAR-CLIP	20371350
MIRT405645	hsa-miR-548ae-5p	PAR-CLIP	20371350
MIRT405647	hsa-miR-548ak	PAR-CLIP	20371350
MIRT405648	hsa-miR-548am-5p	PAR-CLIP	20371350
MIRT405649	hsa-miR-548ap-5p	PAR-CLIP	20371350
MIRT405650	hsa-miR-548aq-5p	PAR-CLIP	20371350
MIRT405651	hsa-miR-548ar-5p	PAR-CLIP	20371350
MIRT405652	hsa-miR-548as-5p	PAR-CLIP	20371350
MIRT405653	hsa-miR-548au-5p	PAR-CLIP	20371350
MIRT405655	hsa-miR-548ay-5p	PAR-CLIP	20371350
MIRT405629	hsa-miR-548b-5p	PAR-CLIP	20371350
MIRT405656	hsa-miR-548bb-5p	PAR-CLIP	20371350
MIRT405631	hsa-miR-548c-5p	PAR-CLIP	20371350
MIRT405632	hsa-miR-548d-5p	PAR-CLIP	20371350
MIRT405637	hsa-miR-548h-5p	PAR-CLIP	20371350
MIRT405638	hsa-miR-548i	PAR-CLIP	20371350
MIRT405633	hsa-miR-548j-5p	PAR-CLIP	20371350
MIRT405642	hsa-miR-548o-5p	PAR-CLIP	20371350
MIRT405639	hsa-miR-548w	PAR-CLIP	20371350
MIRT405641	hsa-miR-548y	PAR-CLIP	20371350
MIRT405628	hsa-miR-559	PAR-CLIP	20371350
MIRT546026	hsa-miR-5700	PAR-CLIP	20371350
MIRT546025	hsa-miR-586	PAR-CLIP	20371350
MIRT405646	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT405634	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT405635	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT405640	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT546024	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT405654	hsa-miR-548aw	PAR-CLIP	20371350
MIRT546022	hsa-miR-548q	PAR-CLIP	20371350
MIRT405627	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT405626	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT405636	hsa-miR-548n	PAR-CLIP	21572407
MIRT405630	hsa-miR-548a-5p	PAR-CLIP	21572407
MIRT405643	hsa-miR-548ab	PAR-CLIP	21572407
MIRT405644	hsa-miR-548ad-5p	PAR-CLIP	21572407
MIRT405645	hsa-miR-548ae-5p	PAR-CLIP	21572407
MIRT405647	hsa-miR-548ak	PAR-CLIP	21572407
MIRT405648	hsa-miR-548am-5p	PAR-CLIP	21572407
MIRT405649	hsa-miR-548ap-5p	PAR-CLIP	21572407
MIRT405650	hsa-miR-548aq-5p	PAR-CLIP	21572407
MIRT405651	hsa-miR-548ar-5p	PAR-CLIP	21572407
MIRT405652	hsa-miR-548as-5p	PAR-CLIP	21572407
MIRT405653	hsa-miR-548au-5p	PAR-CLIP	21572407
MIRT405655	hsa-miR-548ay-5p	PAR-CLIP	21572407
MIRT405629	hsa-miR-548b-5p	PAR-CLIP	21572407
MIRT405656	hsa-miR-548bb-5p	PAR-CLIP	21572407
MIRT405631	hsa-miR-548c-5p	PAR-CLIP	21572407
MIRT405632	hsa-miR-548d-5p	PAR-CLIP	21572407
MIRT405637	hsa-miR-548h-5p	PAR-CLIP	21572407
MIRT405638	hsa-miR-548i	PAR-CLIP	21572407
MIRT405633	hsa-miR-548j-5p	PAR-CLIP	21572407
MIRT405642	hsa-miR-548o-5p	PAR-CLIP	21572407
MIRT405639	hsa-miR-548w	PAR-CLIP	21572407
MIRT405641	hsa-miR-548y	PAR-CLIP	21572407
MIRT405628	hsa-miR-559	PAR-CLIP	21572407
MIRT546026	hsa-miR-5700	PAR-CLIP	21572407
MIRT546025	hsa-miR-586	PAR-CLIP	21572407
MIRT405646	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT405634	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT405635	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT405640	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT546024	hsa-miR-1468-3p	PAR-CLIP	21572407
MIRT546023	hsa-miR-889-3p	PAR-CLIP	21572407
MIRT405654	hsa-miR-548aw	PAR-CLIP	21572407
MIRT546022	hsa-miR-548q	PAR-CLIP	21572407
MIRT405627	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT405626	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT405636	hsa-miR-548n	PAR-CLIP	20371350
MIRT405630	hsa-miR-548a-5p	PAR-CLIP	20371350
MIRT405643	hsa-miR-548ab	PAR-CLIP	20371350
MIRT405644	hsa-miR-548ad-5p	PAR-CLIP	20371350
MIRT405645	hsa-miR-548ae-5p	PAR-CLIP	20371350
MIRT405647	hsa-miR-548ak	PAR-CLIP	20371350
MIRT405648	hsa-miR-548am-5p	PAR-CLIP	20371350
MIRT405649	hsa-miR-548ap-5p	PAR-CLIP	20371350
MIRT405650	hsa-miR-548aq-5p	PAR-CLIP	20371350
MIRT405651	hsa-miR-548ar-5p	PAR-CLIP	20371350
MIRT405652	hsa-miR-548as-5p	PAR-CLIP	20371350
MIRT405653	hsa-miR-548au-5p	PAR-CLIP	20371350
MIRT405655	hsa-miR-548ay-5p	PAR-CLIP	20371350
MIRT405629	hsa-miR-548b-5p	PAR-CLIP	20371350
MIRT405656	hsa-miR-548bb-5p	PAR-CLIP	20371350
MIRT405631	hsa-miR-548c-5p	PAR-CLIP	20371350
MIRT405632	hsa-miR-548d-5p	PAR-CLIP	20371350
MIRT405637	hsa-miR-548h-5p	PAR-CLIP	20371350
MIRT405638	hsa-miR-548i	PAR-CLIP	20371350
MIRT405633	hsa-miR-548j-5p	PAR-CLIP	20371350
MIRT405642	hsa-miR-548o-5p	PAR-CLIP	20371350
MIRT405639	hsa-miR-548w	PAR-CLIP	20371350
MIRT405641	hsa-miR-548y	PAR-CLIP	20371350
MIRT405628	hsa-miR-559	PAR-CLIP	20371350
MIRT546026	hsa-miR-5700	PAR-CLIP	20371350
MIRT546025	hsa-miR-586	PAR-CLIP	20371350
MIRT405646	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT405634	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT405635	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT405640	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT546024	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT405654	hsa-miR-548aw	PAR-CLIP	20371350
MIRT546022	hsa-miR-548q	PAR-CLIP	20371350
MIRT405627	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT405626	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT405636	hsa-miR-548n	PAR-CLIP	20371350
MIRT405630	hsa-miR-548a-5p	PAR-CLIP	20371350
MIRT405643	hsa-miR-548ab	PAR-CLIP	20371350
MIRT405644	hsa-miR-548ad-5p	PAR-CLIP	20371350
MIRT405645	hsa-miR-548ae-5p	PAR-CLIP	20371350
MIRT405647	hsa-miR-548ak	PAR-CLIP	20371350
MIRT405648	hsa-miR-548am-5p	PAR-CLIP	20371350
MIRT405649	hsa-miR-548ap-5p	PAR-CLIP	20371350
MIRT405650	hsa-miR-548aq-5p	PAR-CLIP	20371350
MIRT405651	hsa-miR-548ar-5p	PAR-CLIP	20371350
MIRT405652	hsa-miR-548as-5p	PAR-CLIP	20371350
MIRT405653	hsa-miR-548au-5p	PAR-CLIP	20371350
MIRT405655	hsa-miR-548ay-5p	PAR-CLIP	20371350
MIRT405629	hsa-miR-548b-5p	PAR-CLIP	20371350
MIRT405656	hsa-miR-548bb-5p	PAR-CLIP	20371350
MIRT405631	hsa-miR-548c-5p	PAR-CLIP	20371350
MIRT405632	hsa-miR-548d-5p	PAR-CLIP	20371350
MIRT405637	hsa-miR-548h-5p	PAR-CLIP	20371350
MIRT405638	hsa-miR-548i	PAR-CLIP	20371350
MIRT405633	hsa-miR-548j-5p	PAR-CLIP	20371350
MIRT405642	hsa-miR-548o-5p	PAR-CLIP	20371350
MIRT405639	hsa-miR-548w	PAR-CLIP	20371350
MIRT405641	hsa-miR-548y	PAR-CLIP	20371350
MIRT405628	hsa-miR-559	PAR-CLIP	20371350
MIRT546026	hsa-miR-5700	PAR-CLIP	20371350
MIRT546025	hsa-miR-586	PAR-CLIP	20371350
MIRT405646	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT405634	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT405635	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT405640	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT546024	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT405654	hsa-miR-548aw	PAR-CLIP	20371350
MIRT546022	hsa-miR-548q	PAR-CLIP	20371350
MIRT405627	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT405626	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT405636	hsa-miR-548n	PAR-CLIP	20371350
MIRT405630	hsa-miR-548a-5p	PAR-CLIP	20371350
MIRT405643	hsa-miR-548ab	PAR-CLIP	20371350
MIRT405644	hsa-miR-548ad-5p	PAR-CLIP	20371350
MIRT405645	hsa-miR-548ae-5p	PAR-CLIP	20371350
MIRT405647	hsa-miR-548ak	PAR-CLIP	20371350
MIRT405648	hsa-miR-548am-5p	PAR-CLIP	20371350
MIRT405649	hsa-miR-548ap-5p	PAR-CLIP	20371350
MIRT405650	hsa-miR-548aq-5p	PAR-CLIP	20371350
MIRT405651	hsa-miR-548ar-5p	PAR-CLIP	20371350
MIRT405652	hsa-miR-548as-5p	PAR-CLIP	20371350
MIRT405653	hsa-miR-548au-5p	PAR-CLIP	20371350
MIRT405655	hsa-miR-548ay-5p	PAR-CLIP	20371350
MIRT405629	hsa-miR-548b-5p	PAR-CLIP	20371350
MIRT405656	hsa-miR-548bb-5p	PAR-CLIP	20371350
MIRT405631	hsa-miR-548c-5p	PAR-CLIP	20371350
MIRT405632	hsa-miR-548d-5p	PAR-CLIP	20371350
MIRT405637	hsa-miR-548h-5p	PAR-CLIP	20371350
MIRT405638	hsa-miR-548i	PAR-CLIP	20371350
MIRT405633	hsa-miR-548j-5p	PAR-CLIP	20371350
MIRT405642	hsa-miR-548o-5p	PAR-CLIP	20371350
MIRT405639	hsa-miR-548w	PAR-CLIP	20371350
MIRT405641	hsa-miR-548y	PAR-CLIP	20371350
MIRT405628	hsa-miR-559	PAR-CLIP	20371350
MIRT546026	hsa-miR-5700	PAR-CLIP	20371350
MIRT546025	hsa-miR-586	PAR-CLIP	20371350
MIRT405646	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT405634	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT405635	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT405640	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT546024	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT405654	hsa-miR-548aw	PAR-CLIP	20371350
MIRT546022	hsa-miR-548q	PAR-CLIP	20371350
MIRT405627	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT405626	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT405636	hsa-miR-548n	PAR-CLIP	21572407
MIRT405630	hsa-miR-548a-5p	PAR-CLIP	21572407
MIRT405643	hsa-miR-548ab	PAR-CLIP	21572407
MIRT405644	hsa-miR-548ad-5p	PAR-CLIP	21572407
MIRT405645	hsa-miR-548ae-5p	PAR-CLIP	21572407
MIRT405647	hsa-miR-548ak	PAR-CLIP	21572407
MIRT405648	hsa-miR-548am-5p	PAR-CLIP	21572407
MIRT405649	hsa-miR-548ap-5p	PAR-CLIP	21572407
MIRT405650	hsa-miR-548aq-5p	PAR-CLIP	21572407
MIRT405651	hsa-miR-548ar-5p	PAR-CLIP	21572407
MIRT405652	hsa-miR-548as-5p	PAR-CLIP	21572407
MIRT405653	hsa-miR-548au-5p	PAR-CLIP	21572407
MIRT405655	hsa-miR-548ay-5p	PAR-CLIP	21572407
MIRT405629	hsa-miR-548b-5p	PAR-CLIP	21572407
MIRT405656	hsa-miR-548bb-5p	PAR-CLIP	21572407
MIRT405631	hsa-miR-548c-5p	PAR-CLIP	21572407
MIRT405632	hsa-miR-548d-5p	PAR-CLIP	21572407
MIRT405637	hsa-miR-548h-5p	PAR-CLIP	21572407
MIRT405638	hsa-miR-548i	PAR-CLIP	21572407
MIRT405633	hsa-miR-548j-5p	PAR-CLIP	21572407
MIRT405642	hsa-miR-548o-5p	PAR-CLIP	21572407
MIRT405639	hsa-miR-548w	PAR-CLIP	21572407
MIRT405641	hsa-miR-548y	PAR-CLIP	21572407
MIRT405628	hsa-miR-559	PAR-CLIP	21572407
MIRT546026	hsa-miR-5700	PAR-CLIP	21572407
MIRT546025	hsa-miR-586	PAR-CLIP	21572407
MIRT405646	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT405634	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT405635	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT405640	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT546024	hsa-miR-1468-3p	PAR-CLIP	21572407
MIRT546023	hsa-miR-889-3p	PAR-CLIP	21572407
MIRT405654	hsa-miR-548aw	PAR-CLIP	21572407
MIRT546022	hsa-miR-548q	PAR-CLIP	21572407
MIRT1489247	hsa-miR-127-5p	CLIP-seq
MIRT1489248	hsa-miR-1305	CLIP-seq
MIRT1489249	hsa-miR-19a	CLIP-seq
MIRT1489250	hsa-miR-19b	CLIP-seq
MIRT1489251	hsa-miR-3135b	CLIP-seq
MIRT1489252	hsa-miR-320e	CLIP-seq
MIRT1489253	hsa-miR-4536	CLIP-seq
MIRT1489254	hsa-miR-4709-5p	CLIP-seq
MIRT1489255	hsa-miR-4724-5p	CLIP-seq
MIRT1489256	hsa-miR-4742-3p	CLIP-seq
MIRT1489257	hsa-miR-548h	CLIP-seq
MIRT1489258	hsa-miR-548j	CLIP-seq
MIRT1489259	hsa-miR-769-5p	CLIP-seq
MIRT1489260	hsa-miR-889	CLIP-seq
MIRT2147434	hsa-miR-1264	CLIP-seq
MIRT2367799	hsa-miR-1229	CLIP-seq
MIRT2367800	hsa-miR-1254	CLIP-seq
MIRT2367801	hsa-miR-200b	CLIP-seq
MIRT2367802	hsa-miR-200c	CLIP-seq
MIRT2367803	hsa-miR-3116	CLIP-seq
MIRT2367804	hsa-miR-3140-5p	CLIP-seq
MIRT2367805	hsa-miR-3185	CLIP-seq
MIRT2367806	hsa-miR-3671	CLIP-seq
MIRT2367807	hsa-miR-369-3p	CLIP-seq
MIRT2367808	hsa-miR-429	CLIP-seq
MIRT2367809	hsa-miR-4773	CLIP-seq
MIRT2367810	hsa-miR-4799-5p	CLIP-seq
MIRT2367811	hsa-miR-495	CLIP-seq
MIRT2367812	hsa-miR-513a-3p	CLIP-seq
MIRT2367813	hsa-miR-520d-5p	CLIP-seq
MIRT2367814	hsa-miR-524-5p	CLIP-seq
MIRT2367815	hsa-miR-577	CLIP-seq
MIRT2367816	hsa-miR-661	CLIP-seq
MIRT2367800	hsa-miR-1254	CLIP-seq
MIRT2661355	hsa-miR-1282	CLIP-seq
MIRT2661356	hsa-miR-145	CLIP-seq
MIRT2367803	hsa-miR-3116	CLIP-seq
MIRT2661357	hsa-miR-3124-3p	CLIP-seq
MIRT2661358	hsa-miR-3545-3p	CLIP-seq
MIRT2661359	hsa-miR-3616-5p	CLIP-seq
MIRT2661360	hsa-miR-3647-5p	CLIP-seq
MIRT2661361	hsa-miR-3662	CLIP-seq
MIRT2661362	hsa-miR-3663-5p	CLIP-seq
MIRT2661363	hsa-miR-3692	CLIP-seq
MIRT2661364	hsa-miR-4328	CLIP-seq
MIRT2661365	hsa-miR-4720-3p	CLIP-seq
MIRT2661366	hsa-miR-4795-5p	CLIP-seq
MIRT2661367	hsa-miR-4804-3p	CLIP-seq
MIRT2661368	hsa-miR-483-3p	CLIP-seq
MIRT2661369	hsa-miR-486-3p	CLIP-seq
MIRT2661370	hsa-miR-5096	CLIP-seq
MIRT2661371	hsa-miR-573	CLIP-seq
MIRT2367816	hsa-miR-661	CLIP-seq
MIRT2367800	hsa-miR-1254	CLIP-seq
MIRT2661355	hsa-miR-1282	CLIP-seq
MIRT2367803	hsa-miR-3116	CLIP-seq
MIRT2661358	hsa-miR-3545-3p	CLIP-seq
MIRT2661359	hsa-miR-3616-5p	CLIP-seq
MIRT2661360	hsa-miR-3647-5p	CLIP-seq
MIRT2661361	hsa-miR-3662	CLIP-seq
MIRT2661365	hsa-miR-4720-3p	CLIP-seq
MIRT2661366	hsa-miR-4795-5p	CLIP-seq
MIRT2661367	hsa-miR-4804-3p	CLIP-seq
MIRT2661369	hsa-miR-486-3p	CLIP-seq
MIRT2661371	hsa-miR-573	CLIP-seq
MIRT2367816	hsa-miR-661	CLIP-seq

Gene ontology (GO) Show/Hide all (20)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000398	Process	MRNA splicing, via spliceosome	IDA	28781166
GO:0000398	Process	MRNA splicing, via spliceosome	IEA
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003723	Function	RNA binding	IBA
GO:0005515	Function	Protein binding	IPI	17500595, 28838205, 33961781
GO:0005634	Component	Nucleus	IDA	28781166
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005681	Component	Spliceosomal complex	IEA
GO:0006397	Process	MRNA processing	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0008380	Process	RNA splicing	IBA
GO:0008380	Process	RNA splicing	IEA
GO:0016607	Component	Nuclear speck	IDA	19592703
GO:0016607	Component	Nuclear speck	IEA
GO:0045292	Process	MRNA cis splicing, via spliceosome	IDA	19592703
GO:0046872	Function	Metal ion binding	IEA
GO:0070064	Function	Proline-rich region binding	IPI	19592703
GO:0071005	Component	U2-type precatalytic spliceosome	IDA	28781166
GO:0071011	Component	Precatalytic spliceosome	IBA

Other IDs

• MIM: 604981
• HGNC: 12739
• e!Ensembl: ENSG00000120688

Protein

• UniProt ID: O75554
• Protein name: WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21) (WW domain-containing-binding protein 4)
• Protein function: Involved in pre-mRNA splicing as a component of the spliceosome (PubMed:19592703, PubMed:28781166, PubMed:9724750). May play a role in cross-intron bridging of U1 and U2 snRNPs in the mammalian A complex (PubMed:9724750). {ECO:0000269|PubMed:195
• PDB: 2DK1 , 2JXW , 5O9Z , 6AHD , 7OS1 , 8H6K , 8H6L , 8Q7N , 8QO9 , 8QPE , 8QZS
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00397	WW	165 → 194	WW domain	Domain
  PF00397	WW	124 → 153	WW domain	Domain
  PF06220	zf-U1	8 → 44	U1 zinc finger	Domain

• Sequence:

  MADYWKSQPKKFCDYCKCWIADNRPSVEFHERGKNHKENVAKRISEIKQKSLDKAKEEEK
  ASKEFAAMEAAALKAYQEDLKRLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRK
  KDPSKGRWVEGITSEGYHYYYDLISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTY
  YYNTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGV
  STETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEI
  KQEVESHEEVDLELPSTENEYVSTSEADGGGEPKVVFKEKTVTSLGVMADGVAPVFKKRR
  TENGKSRNLRQRGDDQ

• Sequence length: 376

Pathways

Reactome Pathway:

mRNA Splicing - Major Pathway

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Neurodevelopmental disorder	Likely pathogenic; Pathogenic	rs2541856897, rs2541859093, rs1427720732, rs1355288041	RCV003334354 RCV003334356 RCV003334357 RCV003334358	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Neurodevelopmental disorder with hypotonia, feeding difficulties, facial dysmorphism, and brain abnormalities	Likely pathogenic; Pathogenic	rs2541856897	RCV004577573	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
NEURODEVELOPMENTAL DISORDERS	—	Disgenet	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Developmental Disabilities	Developmental disability	Pubtator	37963460	Associate	★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory Bowel Disease	BEFREE	26511940		★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Intellectual developmental disorder	Pubtator	37963460	Associate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	UNIPROT_DG			★☆☆☆☆ Found in Text Mining only

Related Genes

Sort by: Blended Diseases Pathways Evidence source

MED11 3 shared evidence sourcesGWAS catalog (Neurodevelopmental disorder), ClinVar (Neurodevelopmental disorder), HPO (Neurodevelopmental disorder) Related via 3 shared evidence sources. INTS8 3 shared evidence sourcesGWAS catalog (Neurodevelopmental disorder), ClinVar (Neurodevelopmental disorder), HPO (Neurodevelopmental disorder) Related via 3 shared evidence sources. NAE1 3 shared evidence sourcesGWAS catalog (Neurodevelopmental disorder), ClinVar (Neurodevelopmental disorder), HPO (Neurodevelopmental disorder) Related via 3 shared evidence sources. FRA10AC1 3 shared evidence sourcesGWAS catalog (Neurodevelopmental disorder), ClinVar (Neurodevelopmental disorder), HPO (Neurodevelopmental disorder) Related via 3 shared evidence sources. SMPD4 3 shared evidence sourcesGWAS catalog (Neurodevelopmental disorder), ClinVar (Neurodevelopmental disorder), HPO (Neurodevelopmental disorder) Related via 3 shared evidence sources.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
MED11	0	[]	0	[]	3	["GWAS catalog (Neurodevelopmental disorder)","ClinVar (Neurodevelopmental disorder)","HPO (Neurodevelopmental disorder)"]
INTS8	0	[]	0	[]	3	["GWAS catalog (Neurodevelopmental disorder)","ClinVar (Neurodevelopmental disorder)","HPO (Neurodevelopmental disorder)"]
NAE1	0	[]	0	[]	3	["GWAS catalog (Neurodevelopmental disorder)","ClinVar (Neurodevelopmental disorder)","HPO (Neurodevelopmental disorder)"]
FRA10AC1	0	[]	0	[]	3	["GWAS catalog (Neurodevelopmental disorder)","ClinVar (Neurodevelopmental disorder)","HPO (Neurodevelopmental disorder)"]
SMPD4	0	[]	0	[]	3	["GWAS catalog (Neurodevelopmental disorder)","ClinVar (Neurodevelopmental disorder)","HPO (Neurodevelopmental disorder)"]

Diseases Linked via Similar Genes

Myocardial infarction Linked via 1 of 5 related genesINTS8 Diabetes mellitus type 2 Linked via 1 of 5 related genesINTS8

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Myocardial infarction	1	["INTS8"]
Diabetes mellitus type 2	1	["INTS8"]