VHLL (VHL like)

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Gene miRNA Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 391104
• Gene name: VHL like
• Gene symbol: VHLL
• Synonyms (NCBI Gene): VHLP, VLP
• Chromosome: 1
• Chromosome location: 1q22
• Summary: Von Hippel-Lindau (VHL) tumor suppressor protein is a component of an E3 ubiquitin ligase complex that selectively ubiquitinates the alpha subunit of the hypoxia-inducible factor (HIF) transcription factor for proteasome-mediated degradation. Inactivation

miRNA Show/Hide all (182)

miRTarBase ID	miRNA	Experiments	Reference
MIRT714068	hsa-miR-3145-5p	HITS-CLIP	19536157
MIRT714067	hsa-miR-508-5p	HITS-CLIP	19536157
MIRT714066	hsa-miR-3664-5p	HITS-CLIP	19536157
MIRT714065	hsa-miR-4530	HITS-CLIP	19536157
MIRT714064	hsa-miR-338-3p	HITS-CLIP	19536157
MIRT714063	hsa-miR-766-3p	HITS-CLIP	19536157
MIRT714062	hsa-miR-7114-5p	HITS-CLIP	19536157
MIRT714061	hsa-miR-134-3p	HITS-CLIP	19536157
MIRT714060	hsa-miR-4738-3p	HITS-CLIP	19536157
MIRT714059	hsa-miR-5589-3p	HITS-CLIP	19536157
MIRT714058	hsa-miR-182-3p	HITS-CLIP	19536157
MIRT714057	hsa-miR-597-3p	HITS-CLIP	19536157
MIRT714056	hsa-miR-152-5p	HITS-CLIP	19536157
MIRT714055	hsa-miR-203a-5p	HITS-CLIP	19536157
MIRT714054	hsa-miR-1273g-5p	HITS-CLIP	19536157
MIRT517149	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT517148	hsa-miR-6758-5p	HITS-CLIP	21572407
MIRT517147	hsa-miR-6856-5p	HITS-CLIP	21572407
MIRT517146	hsa-miR-3976	HITS-CLIP	21572407
MIRT517145	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT517144	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT706838	hsa-miR-1245a	HITS-CLIP	21572407
MIRT706837	hsa-miR-8079	HITS-CLIP	21572407
MIRT706836	hsa-miR-6513-3p	HITS-CLIP	21572407
MIRT706835	hsa-miR-6843-3p	HITS-CLIP	21572407
MIRT706834	hsa-miR-6848-3p	HITS-CLIP	21572407
MIRT517149	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT517148	hsa-miR-6758-5p	HITS-CLIP	21572407
MIRT517147	hsa-miR-6856-5p	HITS-CLIP	21572407
MIRT517146	hsa-miR-3976	HITS-CLIP	21572407
MIRT517145	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT517144	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT681380	hsa-miR-1910-3p	HITS-CLIP	23706177
MIRT681379	hsa-miR-6511a-5p	HITS-CLIP	23706177
MIRT681377	hsa-miR-4257	HITS-CLIP	23706177
MIRT681378	hsa-miR-4537	HITS-CLIP	23706177
MIRT681376	hsa-miR-1827	HITS-CLIP	23706177
MIRT681375	hsa-miR-377-5p	HITS-CLIP	23706177
MIRT681374	hsa-miR-6086	HITS-CLIP	23706177
MIRT681372	hsa-miR-2467-3p	HITS-CLIP	23706177
MIRT681373	hsa-miR-6499-3p	HITS-CLIP	23706177
MIRT681371	hsa-miR-455-3p	HITS-CLIP	23706177
MIRT681370	hsa-miR-6516-5p	HITS-CLIP	23706177
MIRT517148	hsa-miR-6758-5p	PAR-CLIP	20371350
MIRT517147	hsa-miR-6856-5p	PAR-CLIP	20371350
MIRT517146	hsa-miR-3976	PAR-CLIP	20371350
MIRT517145	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT517144	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT517149	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT517148	hsa-miR-6758-5p	PAR-CLIP	21572407
MIRT517147	hsa-miR-6856-5p	PAR-CLIP	21572407
MIRT517146	hsa-miR-3976	PAR-CLIP	21572407
MIRT517145	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT517144	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT517149	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT517148	hsa-miR-6758-5p	PAR-CLIP	21572407
MIRT517147	hsa-miR-6856-5p	PAR-CLIP	21572407
MIRT517146	hsa-miR-3976	PAR-CLIP	21572407
MIRT517145	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT517144	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT517149	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT517148	hsa-miR-6758-5p	PAR-CLIP	21572407
MIRT517147	hsa-miR-6856-5p	PAR-CLIP	21572407
MIRT517146	hsa-miR-3976	PAR-CLIP	21572407
MIRT517145	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT517144	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT517149	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT517148	hsa-miR-6758-5p	PAR-CLIP	21572407
MIRT517147	hsa-miR-6856-5p	PAR-CLIP	21572407
MIRT517146	hsa-miR-3976	PAR-CLIP	21572407
MIRT517145	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT517144	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT517149	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT517157	hsa-miR-590-3p	PAR-CLIP	23446348
MIRT517156	hsa-miR-7845-5p	PAR-CLIP	23446348
MIRT517155	hsa-miR-4735-5p	PAR-CLIP	23446348
MIRT517154	hsa-miR-4794	PAR-CLIP	23446348
MIRT517153	hsa-miR-664a-5p	PAR-CLIP	23446348
MIRT517152	hsa-miR-4775	PAR-CLIP	23446348
MIRT517151	hsa-miR-411-5p	PAR-CLIP	23446348
MIRT517150	hsa-miR-6083	PAR-CLIP	23446348
MIRT517149	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT517148	hsa-miR-6758-5p	PAR-CLIP	23446348
MIRT517147	hsa-miR-6856-5p	PAR-CLIP	23446348
MIRT517146	hsa-miR-3976	PAR-CLIP	23446348
MIRT517145	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT517144	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT517146	hsa-miR-3976	PAR-CLIP	27292025
MIRT681371	hsa-miR-455-3p	PAR-CLIP	27292025
MIRT714067	hsa-miR-508-5p	PAR-CLIP	27292025
MIRT681373	hsa-miR-6499-3p	PAR-CLIP	27292025
MIRT681370	hsa-miR-6516-5p	PAR-CLIP	27292025
MIRT517148	hsa-miR-6758-5p	PAR-CLIP	27292025
MIRT517147	hsa-miR-6856-5p	PAR-CLIP	27292025
MIRT714063	hsa-miR-766-3p	PAR-CLIP	27292025
MIRT714068	hsa-miR-3145-5p	HITS-CLIP	19536157
MIRT714067	hsa-miR-508-5p	HITS-CLIP	19536157
MIRT714066	hsa-miR-3664-5p	HITS-CLIP	19536157
MIRT714065	hsa-miR-4530	HITS-CLIP	19536157
MIRT714064	hsa-miR-338-3p	HITS-CLIP	19536157
MIRT714063	hsa-miR-766-3p	HITS-CLIP	19536157
MIRT714062	hsa-miR-7114-5p	HITS-CLIP	19536157
MIRT714061	hsa-miR-134-3p	HITS-CLIP	19536157
MIRT714060	hsa-miR-4738-3p	HITS-CLIP	19536157
MIRT714059	hsa-miR-5589-3p	HITS-CLIP	19536157
MIRT714058	hsa-miR-182-3p	HITS-CLIP	19536157
MIRT714057	hsa-miR-597-3p	HITS-CLIP	19536157
MIRT714056	hsa-miR-152-5p	HITS-CLIP	19536157
MIRT714055	hsa-miR-203a-5p	HITS-CLIP	19536157
MIRT714054	hsa-miR-1273g-5p	HITS-CLIP	19536157
MIRT517149	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT517148	hsa-miR-6758-5p	HITS-CLIP	21572407
MIRT517147	hsa-miR-6856-5p	HITS-CLIP	21572407
MIRT517146	hsa-miR-3976	HITS-CLIP	21572407
MIRT517145	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT517144	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT706838	hsa-miR-1245a	HITS-CLIP	21572407
MIRT706837	hsa-miR-8079	HITS-CLIP	21572407
MIRT706836	hsa-miR-6513-3p	HITS-CLIP	21572407
MIRT706835	hsa-miR-6843-3p	HITS-CLIP	21572407
MIRT706834	hsa-miR-6848-3p	HITS-CLIP	21572407
MIRT517149	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT517148	hsa-miR-6758-5p	HITS-CLIP	21572407
MIRT517147	hsa-miR-6856-5p	HITS-CLIP	21572407
MIRT517146	hsa-miR-3976	HITS-CLIP	21572407
MIRT517145	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT517144	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT681380	hsa-miR-1910-3p	HITS-CLIP	23706177
MIRT681379	hsa-miR-6511a-5p	HITS-CLIP	23706177
MIRT681377	hsa-miR-4257	HITS-CLIP	23706177
MIRT681378	hsa-miR-4537	HITS-CLIP	23706177
MIRT681376	hsa-miR-1827	HITS-CLIP	23706177
MIRT681375	hsa-miR-377-5p	HITS-CLIP	23706177
MIRT681374	hsa-miR-6086	HITS-CLIP	23706177
MIRT681372	hsa-miR-2467-3p	HITS-CLIP	23706177
MIRT681373	hsa-miR-6499-3p	HITS-CLIP	23706177
MIRT681371	hsa-miR-455-3p	HITS-CLIP	23706177
MIRT681370	hsa-miR-6516-5p	HITS-CLIP	23706177
MIRT517148	hsa-miR-6758-5p	PAR-CLIP	20371350
MIRT517147	hsa-miR-6856-5p	PAR-CLIP	20371350
MIRT517146	hsa-miR-3976	PAR-CLIP	20371350
MIRT517145	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT517144	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT517149	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT517148	hsa-miR-6758-5p	PAR-CLIP	21572407
MIRT517147	hsa-miR-6856-5p	PAR-CLIP	21572407
MIRT517146	hsa-miR-3976	PAR-CLIP	21572407
MIRT517145	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT517144	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT517149	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT517148	hsa-miR-6758-5p	PAR-CLIP	21572407
MIRT517147	hsa-miR-6856-5p	PAR-CLIP	21572407
MIRT517146	hsa-miR-3976	PAR-CLIP	21572407
MIRT517145	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT517144	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT517149	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT517148	hsa-miR-6758-5p	PAR-CLIP	21572407
MIRT517147	hsa-miR-6856-5p	PAR-CLIP	21572407
MIRT517146	hsa-miR-3976	PAR-CLIP	21572407
MIRT517145	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT517144	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT517149	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT517148	hsa-miR-6758-5p	PAR-CLIP	21572407
MIRT517147	hsa-miR-6856-5p	PAR-CLIP	21572407
MIRT517146	hsa-miR-3976	PAR-CLIP	21572407
MIRT517145	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT517144	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT517149	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT517157	hsa-miR-590-3p	PAR-CLIP	23446348
MIRT517156	hsa-miR-7845-5p	PAR-CLIP	23446348
MIRT517155	hsa-miR-4735-5p	PAR-CLIP	23446348
MIRT517154	hsa-miR-4794	PAR-CLIP	23446348
MIRT517153	hsa-miR-664a-5p	PAR-CLIP	23446348
MIRT517152	hsa-miR-4775	PAR-CLIP	23446348
MIRT517151	hsa-miR-411-5p	PAR-CLIP	23446348
MIRT517150	hsa-miR-6083	PAR-CLIP	23446348
MIRT517149	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT517148	hsa-miR-6758-5p	PAR-CLIP	23446348
MIRT517147	hsa-miR-6856-5p	PAR-CLIP	23446348
MIRT517146	hsa-miR-3976	PAR-CLIP	23446348
MIRT517145	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT517144	hsa-miR-190a-3p	PAR-CLIP	23446348

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 32296183

Other IDs

• MIM: 619650
• HGNC: 30666
• e!Ensembl: ENSG00000189030

Protein

• UniProt ID: Q6RSH7
• Protein name: von Hippel-Lindau-like protein (VHL-like protein) (VLP)
• Protein function: Functions as a dominant-negative VHL to serve as a protector of HIFalpha.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01847	VHL	45 → 126	VHL beta domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Abundantly expressed in the placenta. {ECO:0000269|PubMed:14757845}.
• Sequence:

  MPWRAGNGVGLEAQAGTQEAGPEEYCQEELGAEEEMAARAAWPVLRSVNSRELSRIIICN
  HSPRIVLPVWLNYYGKLLPYLTLLPGRDFRIHNFRSHPWLFRDARTHDKLLVNQTELFVP
  SSNVNGQPVFANITLQCIP

• Sequence length: 139

Related Genes

No strongly related genes found yet for VHLL.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to VHLL.