Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	728386
Gene name	Ubiquitin specific peptidase 17 like family member 5
Gene symbol	USP17L5
Synonyms (NCBI Gene)	-
Chromosome	4
Chromosome location	4p16.1

14 Show/Hide all (14)

GO ID	Ontology	Definition	Evidence
GO:0004843	Function	Cysteine-type deubiquitinase activity	IBA
GO:0004843	Function	Cysteine-type deubiquitinase activity	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005829	Component	Cytosol	IBA
GO:0006508	Process	Proteolysis	IEA
GO:0006915	Process	Apoptotic process	IEA
GO:0008233	Function	Peptidase activity	IEA
GO:0008234	Function	Cysteine-type peptidase activity	IEA
GO:0016579	Process	Protein deubiquitination	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0031647	Process	Regulation of protein stability	IBA
GO:0042981	Process	Regulation of apoptotic process	IBA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

A8MUK1

Protein name

Ubiquitin carboxyl-terminal hydrolase 17-like protein 5 (EC 3.4.19.12) (Deubiquitinating enzyme 17-like protein 5) (Ubiquitin thioesterase 17-like protein 5) (Ubiquitin-specific-processing protease 17-like protein 5)

Protein function

Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular respon

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00443	UCH	80 → 372	Ubiquitin carboxyl-terminal hydrolase	Family
PF04774	HABP4_PAI-RBP1	365 → 457	Hyaluronan / mRNA binding family	Family

Sequence

MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVAR
QLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRH
KGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH
KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQL
AKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPEC
LDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSIT
SVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPEL
DEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHP
EQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ

Sequence length

530

Interactions

View interactions

Reactome Pathway
Ub-specific processing proteases

Related Genes Genes most often co-reported with USP17L5 across shared curated disease and pathway associations. 0 Download as csv Download as pdf
No strongly related genes found yet for USP17L5.

Diseases Linked via Similar Genes Diseases curated for genes most similar to USP17L5 (see Related Genes above), that are NOT already directly curated for USP17L5 itself -- a lead worth checking, not a confirmed association. 0 Download as csv Download as pdf
No additional diseases found yet through genes similar to USP17L5.

USP17L5 (ubiquitin specific peptidase 17 like family member 5)

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