Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	401447
Gene name	Ubiquitin specific peptidase 17 like family member 1
Gene symbol	USP17L1
Synonyms (NCBI Gene)	USP17L1P
Chromosome	8
Chromosome location	8p23.1

14 Show/Hide all (14)

GO ID	Ontology	Definition	Evidence
GO:0004843	Function	Cysteine-type deubiquitinase activity	IBA
GO:0004843	Function	Cysteine-type deubiquitinase activity	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005829	Component	Cytosol	IBA
GO:0006508	Process	Proteolysis	IEA
GO:0006915	Process	Apoptotic process	IEA
GO:0008233	Function	Peptidase activity	IEA
GO:0008234	Function	Cysteine-type peptidase activity	IEA
GO:0016579	Process	Protein deubiquitination	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0031647	Process	Regulation of protein stability	IBA
GO:0042981	Process	Regulation of apoptotic process	IBA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q7RTZ2

Protein name

Ubiquitin carboxyl-terminal hydrolase 17-like protein 1 (EC 3.4.19.12) (Deubiquitinating enzyme 17-like protein 1) (Ubiquitin thioesterase 17-like protein 1) (Ubiquitin-specific-processing protease 17-like protein 1)

Protein function

Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular respon

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00443	UCH	80 → 372	Ubiquitin carboxyl-terminal hydrolase	Family

Sequence

MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVAR
QLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRP
KCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGH
KQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQL
VKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPEC
LDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSII
SVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPEL
DEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHP
EQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ

Sequence length

530

Interactions

View interactions

Reactome Pathway
Ub-specific processing proteases

Related Genes Genes most often co-reported with USP17L1 across shared curated disease and pathway associations. 0 Download as csv Download as pdf
No strongly related genes found yet for USP17L1.

Diseases Linked via Similar Genes Diseases curated for genes most similar to USP17L1 (see Related Genes above), that are NOT already directly curated for USP17L1 itself -- a lead worth checking, not a confirmed association. 0 Download as csv Download as pdf
No additional diseases found yet through genes similar to USP17L1.

USP17L1 (ubiquitin specific peptidase 17 like family member 1)

Save This Analysis