UNC93A (unc-93 homolog A)

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Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 54346
• Gene name: Unc-93 homolog A
• Gene symbol: UNC93A
• Synonyms (NCBI Gene): Unc-93A, dJ366N23.1, dJ366N23.2
• Chromosome: 6
• Chromosome location: 6q27

miRNA Show/Hide all (181)

miRTarBase ID	miRNA	Experiments	Reference
MIRT630935	hsa-miR-548ac	HITS-CLIP	23824327
MIRT630934	hsa-miR-548bb-3p	HITS-CLIP	23824327
MIRT630933	hsa-miR-548d-3p	HITS-CLIP	23824327
MIRT630932	hsa-miR-548h-3p	HITS-CLIP	23824327
MIRT630931	hsa-miR-548z	HITS-CLIP	23824327
MIRT630930	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT630929	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT630928	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT630927	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT630926	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT630925	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT630924	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT630923	hsa-miR-4690-5p	HITS-CLIP	23824327
MIRT630922	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT630921	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT638021	hsa-miR-6792-5p	HITS-CLIP	23824327
MIRT638020	hsa-miR-4503	HITS-CLIP	23824327
MIRT638019	hsa-miR-7856-5p	HITS-CLIP	23824327
MIRT630935	hsa-miR-548ac	HITS-CLIP	23824327
MIRT630934	hsa-miR-548bb-3p	HITS-CLIP	23824327
MIRT630933	hsa-miR-548d-3p	HITS-CLIP	23824327
MIRT630932	hsa-miR-548h-3p	HITS-CLIP	23824327
MIRT630931	hsa-miR-548z	HITS-CLIP	23824327
MIRT630930	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT630929	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT630928	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT630927	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT630926	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT630925	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT630924	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT630923	hsa-miR-4690-5p	HITS-CLIP	23824327
MIRT630922	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT630921	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT630935	hsa-miR-548ac	HITS-CLIP	23824327
MIRT630934	hsa-miR-548bb-3p	HITS-CLIP	23824327
MIRT630933	hsa-miR-548d-3p	HITS-CLIP	23824327
MIRT630932	hsa-miR-548h-3p	HITS-CLIP	23824327
MIRT630931	hsa-miR-548z	HITS-CLIP	23824327
MIRT630930	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT630929	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT630928	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT630927	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT630926	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT630925	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT630924	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT630923	hsa-miR-4690-5p	HITS-CLIP	23824327
MIRT630922	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT630921	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT630935	hsa-miR-548ac	HITS-CLIP	23824327
MIRT630934	hsa-miR-548bb-3p	HITS-CLIP	23824327
MIRT630933	hsa-miR-548d-3p	HITS-CLIP	23824327
MIRT630932	hsa-miR-548h-3p	HITS-CLIP	23824327
MIRT630931	hsa-miR-548z	HITS-CLIP	23824327
MIRT630930	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT630929	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT630928	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT630927	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT630926	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT630925	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT630924	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT630923	hsa-miR-4690-5p	HITS-CLIP	23824327
MIRT630922	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT630921	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT638021	hsa-miR-6792-5p	HITS-CLIP	23824327
MIRT638020	hsa-miR-4503	HITS-CLIP	23824327
MIRT638019	hsa-miR-7856-5p	HITS-CLIP	23824327
MIRT630935	hsa-miR-548ac	HITS-CLIP	23824327
MIRT630934	hsa-miR-548bb-3p	HITS-CLIP	23824327
MIRT630933	hsa-miR-548d-3p	HITS-CLIP	23824327
MIRT630932	hsa-miR-548h-3p	HITS-CLIP	23824327
MIRT630931	hsa-miR-548z	HITS-CLIP	23824327
MIRT630930	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT630929	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT630928	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT630927	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT630926	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT630925	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT630924	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT630923	hsa-miR-4690-5p	HITS-CLIP	23824327
MIRT630922	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT630921	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT630935	hsa-miR-548ac	HITS-CLIP	23824327
MIRT630934	hsa-miR-548bb-3p	HITS-CLIP	23824327
MIRT630933	hsa-miR-548d-3p	HITS-CLIP	23824327
MIRT630932	hsa-miR-548h-3p	HITS-CLIP	23824327
MIRT630931	hsa-miR-548z	HITS-CLIP	23824327
MIRT630930	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT630929	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT630928	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT630927	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT630926	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT630925	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT630924	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT630923	hsa-miR-4690-5p	HITS-CLIP	23824327
MIRT630922	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT630921	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT638021	hsa-miR-6792-5p	HITS-CLIP	23824327
MIRT638020	hsa-miR-4503	HITS-CLIP	23824327
MIRT638019	hsa-miR-7856-5p	HITS-CLIP	23824327
MIRT630935	hsa-miR-548ac	HITS-CLIP	23824327
MIRT630934	hsa-miR-548bb-3p	HITS-CLIP	23824327
MIRT630933	hsa-miR-548d-3p	HITS-CLIP	23824327
MIRT630932	hsa-miR-548h-3p	HITS-CLIP	23824327
MIRT630931	hsa-miR-548z	HITS-CLIP	23824327
MIRT630930	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT630929	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT630928	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT630927	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT630926	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT630925	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT630924	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT630923	hsa-miR-4690-5p	HITS-CLIP	23824327
MIRT630922	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT630921	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT630935	hsa-miR-548ac	HITS-CLIP	23824327
MIRT630934	hsa-miR-548bb-3p	HITS-CLIP	23824327
MIRT630933	hsa-miR-548d-3p	HITS-CLIP	23824327
MIRT630932	hsa-miR-548h-3p	HITS-CLIP	23824327
MIRT630931	hsa-miR-548z	HITS-CLIP	23824327
MIRT630930	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT630929	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT630928	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT630927	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT630926	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT630925	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT630924	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT630923	hsa-miR-4690-5p	HITS-CLIP	23824327
MIRT630922	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT630921	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT630935	hsa-miR-548ac	HITS-CLIP	23824327
MIRT630934	hsa-miR-548bb-3p	HITS-CLIP	23824327
MIRT630933	hsa-miR-548d-3p	HITS-CLIP	23824327
MIRT630932	hsa-miR-548h-3p	HITS-CLIP	23824327
MIRT630931	hsa-miR-548z	HITS-CLIP	23824327
MIRT630930	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT630929	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT630928	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT630927	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT630926	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT630925	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT630924	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT630923	hsa-miR-4690-5p	HITS-CLIP	23824327
MIRT630922	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT630921	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT638021	hsa-miR-6792-5p	HITS-CLIP	23824327
MIRT638020	hsa-miR-4503	HITS-CLIP	23824327
MIRT638019	hsa-miR-7856-5p	HITS-CLIP	23824327
MIRT630935	hsa-miR-548ac	HITS-CLIP	23824327
MIRT630934	hsa-miR-548bb-3p	HITS-CLIP	23824327
MIRT630933	hsa-miR-548d-3p	HITS-CLIP	23824327
MIRT630932	hsa-miR-548h-3p	HITS-CLIP	23824327
MIRT630931	hsa-miR-548z	HITS-CLIP	23824327
MIRT630930	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT630929	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT630928	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT630927	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT630926	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT630925	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT630924	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT630923	hsa-miR-4690-5p	HITS-CLIP	23824327
MIRT630922	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT630921	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT1475701	hsa-miR-4269	CLIP-seq
MIRT1475702	hsa-miR-4514	CLIP-seq
MIRT1475703	hsa-miR-4692	CLIP-seq
MIRT1475704	hsa-miR-4742-5p	CLIP-seq
MIRT1475705	hsa-miR-627	CLIP-seq
MIRT1475706	hsa-miR-924	CLIP-seq
MIRT2143355	hsa-miR-2052	CLIP-seq
MIRT2143356	hsa-miR-3691-3p	CLIP-seq
MIRT2143357	hsa-miR-640	CLIP-seq
MIRT2143358	hsa-miR-873	CLIP-seq
MIRT2462948	hsa-miR-1273f	CLIP-seq
MIRT2462949	hsa-miR-143	CLIP-seq
MIRT2462950	hsa-miR-218	CLIP-seq
MIRT2462951	hsa-miR-3150b-3p	CLIP-seq
MIRT2462952	hsa-miR-4663	CLIP-seq
MIRT2462953	hsa-miR-4689	CLIP-seq
MIRT2462954	hsa-miR-4708-5p	CLIP-seq
MIRT2462955	hsa-miR-4770	CLIP-seq
MIRT2462956	hsa-miR-4784	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005886	Component	Plasma membrane	IDA	12381271
GO:0005886	Component	Plasma membrane	IEA
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	NAS	12381271

Other IDs

• MIM: 607995
• HGNC: 12570
• e!Ensembl: ENSG00000112494

Protein

• UniProt ID: Q86WB7
• Protein name: Protein unc-93 homolog A (HmUnc-93A) (Unc-93A)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF05978	UNC-93	11 → 168	Ion channel regulatory protein UNC-93	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed in testis, small intestine, spleen, prostate and ovary. {ECO:0000269|PubMed:12381271}.
• Sequence:

  MDRSLRNVLVVSFGFLLLFTAYGGLQSLQSSLYSEEGLGVTALSTLYGGMLLSSMFLPPL
  LIERLGCKGTIILSMCGYVAFSVGNFFASWYTLIPTSILLGLGAAPLWSAQCTYLTITGN
  THAEKAGKRGKDMVNQYFGIFFLIFQSSGVWGNLISSLVFGQTPSQETLPEEQLTSCGAS
  DCLMATTTTNSTQRPSQQLVYTLLGIYTGSGVLAVLMIAAFLQPIRDVQRESEGEKKSVP
  FWSTLLSTFKLYRDKRLCLLILLPLYSGLQQGFLSSEYTRSYVTCTLGIQFVGYVMICFS
  ATDALCSVLYGKVSQYTGRAVLYVLGAVTHVSCMIALLLWRPRADHLAVFFVFSGLWGVA
  DAVWQTQNNALYGVLFEKSKEAAFANYRLWEALGFVIAFGYSMFLCVHVKLYILLGVLSL
  TMVAYGLVECVESKNPIRPHAPGQVNQAEDEEIQTKM

• Sequence length: 457

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Familial cancer of breast	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	12381271		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	12381271		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	12381271		★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	12381271		★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	LHGDN	12381271		★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for UNC93A.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to UNC93A.