UBOX5 (U-box domain containing 5)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 22888 |
| Gene name | U-box domain containing 5 |
| Gene symbol | UBOX5 |
| Synonyms (NCBI Gene) |
RNF37UBCE7IP5UIP5hUIP5
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| Chromosome | 20 |
| Chromosome location | 20p13 |
| Summary | This gene encodes a U-box domain containing protein. The encoded protein interacts with E2 enzymes and may play a role in the ubiquitination pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O94941 | ||||||||||
| Protein name | RING finger protein 37 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RNF37) (U-box domain-containing protein 5) (UbcM4-interacting protein 5) (hUIP5) (Ubiquitin-conjugating enzyme 7-interacting protein 5) | ||||||||||
| Protein function | May have a ubiquitin-protein ligase activity acting as an E3 ubiquitin-protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in liver, heart, brain, kidney and testis. {ECO:0000269|PubMed:11435423}. | ||||||||||
| Sequence |
MVINLCLPQFRPRIHCNKISADGYEVENLISEDLTKRSHGFRTEYFIKPPVYVTVSFPFN |
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| Sequence length | 541 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Related Genes
Genes most often co-reported with UBOX5 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to UBOX5 (see Related Genes above), that are NOT already directly curated for UBOX5 itself -- a lead worth checking, not a confirmed association.
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