TUBE1 (tubulin epsilon 1)

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Gene miRNA Gene ontology Other IDs Protein Pathways Diseases linked via similar genes

Gene

• Entrez ID: 51175
• Gene name: Tubulin epsilon 1
• Gene symbol: TUBE1
• Synonyms (NCBI Gene): TUBE, dJ142L7.2
• Chromosome: 6
• Chromosome location: 6q21
• Summary: This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization

miRNA Show/Hide all (37)

miRTarBase ID	miRNA	Experiments	Reference
MIRT022541	hsa-miR-124-3p	Microarray	18668037
MIRT1463500	hsa-miR-148a	CLIP-seq
MIRT1463501	hsa-miR-148b	CLIP-seq
MIRT1463502	hsa-miR-152	CLIP-seq
MIRT1463503	hsa-miR-2467-5p	CLIP-seq
MIRT1463504	hsa-miR-3120-3p	CLIP-seq
MIRT1463505	hsa-miR-3161	CLIP-seq
MIRT1463506	hsa-miR-3163	CLIP-seq
MIRT1463507	hsa-miR-3188	CLIP-seq
MIRT1463508	hsa-miR-3975	CLIP-seq
MIRT1463509	hsa-miR-4272	CLIP-seq
MIRT1463510	hsa-miR-4517	CLIP-seq
MIRT1463511	hsa-miR-4668-3p	CLIP-seq
MIRT1463512	hsa-miR-4709-3p	CLIP-seq
MIRT1463513	hsa-miR-485-5p	CLIP-seq
MIRT1463514	hsa-miR-545	CLIP-seq
MIRT1463515	hsa-miR-548p	CLIP-seq
MIRT1463516	hsa-miR-642b	CLIP-seq
MIRT1463500	hsa-miR-148a	CLIP-seq
MIRT1463501	hsa-miR-148b	CLIP-seq
MIRT1463502	hsa-miR-152	CLIP-seq
MIRT1463510	hsa-miR-4517	CLIP-seq
MIRT1463512	hsa-miR-4709-3p	CLIP-seq
MIRT2360085	hsa-miR-518a-5p	CLIP-seq
MIRT2360086	hsa-miR-527	CLIP-seq
MIRT2360087	hsa-miR-561	CLIP-seq
MIRT1463516	hsa-miR-642b	CLIP-seq
MIRT2360088	hsa-miR-7	CLIP-seq
MIRT2653334	hsa-miR-3653	CLIP-seq
MIRT2653335	hsa-miR-3658	CLIP-seq
MIRT2653336	hsa-miR-3974	CLIP-seq
MIRT2653337	hsa-miR-494	CLIP-seq
MIRT2653338	hsa-miR-548l	CLIP-seq
MIRT2653334	hsa-miR-3653	CLIP-seq
MIRT2653335	hsa-miR-3658	CLIP-seq
MIRT2653336	hsa-miR-3974	CLIP-seq
MIRT2653337	hsa-miR-494	CLIP-seq

Gene ontology (GO) Show/Hide all (17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0000226	Process	Microtubule cytoskeleton organization	IBA
GO:0000242	Component	Pericentriolar material	TAS	10620804
GO:0000278	Process	Mitotic cell cycle	IBA
GO:0005200	Function	Structural constituent of cytoskeleton	IBA
GO:0005200	Function	Structural constituent of cytoskeleton	TAS	10620804
GO:0005525	Function	GTP binding	IBA
GO:0005525	Function	GTP binding	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IBA
GO:0005874	Component	Microtubule	IEA
GO:0007017	Process	Microtubule-based process	IEA
GO:0007098	Process	Centrosome cycle	TAS	10620804
GO:0015630	Component	Microtubule cytoskeleton	IEA

Other IDs

• MIM: 607345
• HGNC: 20775
• e!Ensembl: ENSG00000074935

Protein

• UniProt ID: Q9UJT0
• Protein name: Tubulin epsilon chain (Epsilon-tubulin)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00091	Tubulin	3 → 219	Tubulin/FtsZ family, GTPase domain	Domain
  PF03953	Tubulin_C	294 → 414	Tubulin C-terminal domain	Domain

• Sequence:

  MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTRVVGDGGSIS
  KGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGSLY
  QDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPS
  GEDDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSLV
  TSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYLV
  SSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQISDLR
  RNIERLKPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKERFMRLY
  KKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQLDATKNMPVQDLPRLSIAM

• Sequence length: 475

Pathways

KEGG Pathway:

Motor proteins

Related Genes

No strongly related genes found yet for TUBE1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to TUBE1.