Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	440307
Gene name	Tubulin tyrosine ligase like 13
Gene symbol	TTLL13
Synonyms (NCBI Gene)	TTLL13P
Chromosome	15
Chromosome location	15q26.1

13 Show/Hide all (13)

GO ID	Ontology	Definition	Evidence
GO:0000166	Function	Nucleotide binding	IEA
GO:0001578	Process	Microtubule bundle formation	IBA
GO:0005524	Function	ATP binding	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005874	Component	Microtubule	IEA
GO:0015631	Function	Tubulin binding	IBA
GO:0016874	Function	Ligase activity	IEA
GO:0036064	Component	Ciliary basal body	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:0070740	Function	Tubulin-glutamic acid ligase activity	IBA
GO:0070740	Function	Tubulin-glutamic acid ligase activity	ISS
GO:0070740	Function	Tubulin-glutamic acid ligase activity	TAS
GO:0106438	Function	Protein-glutamic acid ligase activity, elongating	IEA

MIM	HGNC	e!Ensembl
620485	32484	ENSG00000213471

A6NNM8

Protein name

Tubulin polyglutamylase TTLL13 (EC 6.3.2.-) (Tubulin tyrosine ligase like 13) (Tubulin tyrosine ligase-like family member 13 pseudogene) (Tubulin--tyrosine ligase-like protein 13)

Protein function

Polyglutamylase which modifies tubulin, generating polyglutamate side chains of variable lengths on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin. Mediates ATP-dependent polyglutamate side-chain el

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03133	TTL	131 → 427	Tubulin-tyrosine ligase family	Family

Sequence

MEPSTCRTMESEEDYVEEKESEKCVKEGVTNPSNSSQQALLKADYKALKNGVPSPIMATK
IPKKVIAPVDTGDLEAGRRKRRRKRRSLAINLTNCKYESVRRAAQMCGLKEVGEDEEWTL
YWTDCAVSLERVMDMKRFQKINHFPGMTEICRKDLLARNLNRMYKLYPSEYNIFPRTWCL
PADYGDFQSYGRQRKARTYICKPDSGCQGRGIFITRNPREIKPGEHMICQQYISKPLLID
GFKFDMRVYVLITSCDPLRIFTYEEGLARFATTPYMEPSHNNLDNVCMHLTNYAINKHNE
NFVRDGAVGSKRKLSTLNIWLQEHSYNPGELWGDIEDIIIKTIISAHSVLRHNYRTCFPQ
YLNGGTCACFEILGFDILLDHKLKPWLLEVNHSPSFTTDSCLDQEVKDALLCDAMTLVNL
RGCDKRKVMEEDKRRVKERLFQCYRQPRESRKEKTESSHVAMLDQERYEDSHLGKYRRIY
PGPDTEKYARFFKHNGSLFQETAASKAREECARQQLEEIRLKQEQQETSGTKRQKARDQN
QGESAGEKSRPRAGLQSLSTHLAYRNRNWEKELLPGQLDTMRPQEIVEEEELERMKALLQ
RETLIRSLGIVEQLTRLQHPGPQGQKKLHESRDRLGSQELKSMSLVLLVLLRGAATEQGA
PHFLHPVLPHESIPRILGALPSMNAAIPHVPRYHLQPKNFNWTGEPAAINSCSLSMKKAG
RCYFSSARIRLTSQGQASRRLEAINRVLAGSVPPTLTPKQGYFLQPERVASDSWTECTLP
SMVNSEHRAAKVPLCPASAPMLQRSRALLNINQFR

Sequence length

815

Interactions

View interactions

Related Genes Genes most often co-reported with TTLL13 across shared curated disease and pathway associations. 0 Download as csv Download as pdf
No strongly related genes found yet for TTLL13.

Diseases Linked via Similar Genes Diseases curated for genes most similar to TTLL13 (see Related Genes above), that are NOT already directly curated for TTLL13 itself -- a lead worth checking, not a confirmed association. 0 Download as csv Download as pdf
No additional diseases found yet through genes similar to TTLL13.

TTLL13 (tubulin tyrosine ligase like 13)

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