TRIM74 (tripartite motif containing 74)

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Gene miRNA Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 378108
• Gene name: Tripartite motif containing 74
• Gene symbol: TRIM74
• Synonyms (NCBI Gene): TRIM50C
• Chromosome: 7
• Chromosome location: 7q11.23

miRNA Show/Hide all (52)

miRTarBase ID	miRNA	Experiments	Reference
MIRT017752	hsa-miR-335-5p	Microarray	18185580
MIRT515447	hsa-miR-548av-5p	PAR-CLIP	23446348
MIRT515446	hsa-miR-548k	PAR-CLIP	23446348
MIRT515444	hsa-miR-8054	PAR-CLIP	23446348
MIRT515445	hsa-miR-1278	PAR-CLIP	23446348
MIRT515443	hsa-miR-556-5p	PAR-CLIP	23446348
MIRT515441	hsa-miR-3973	PAR-CLIP	23446348
MIRT515442	hsa-miR-186-3p	PAR-CLIP	23446348
MIRT515440	hsa-miR-619-5p	PAR-CLIP	23446348
MIRT515439	hsa-miR-6506-5p	PAR-CLIP	23446348
MIRT515438	hsa-miR-610	PAR-CLIP	23446348
MIRT515437	hsa-miR-6511b-5p	PAR-CLIP	23446348
MIRT515436	hsa-miR-6811-5p	PAR-CLIP	23446348
MIRT515434	hsa-miR-5089-5p	PAR-CLIP	23446348
MIRT496239	hsa-miR-6858-3p	PAR-CLIP	22291592
MIRT496238	hsa-miR-1910-3p	PAR-CLIP	22291592
MIRT496237	hsa-miR-6511a-5p	PAR-CLIP	22291592
MIRT496236	hsa-miR-6808-5p	PAR-CLIP	22291592
MIRT496235	hsa-miR-6893-5p	PAR-CLIP	22291592
MIRT496234	hsa-miR-940	PAR-CLIP	22291592
MIRT496233	hsa-miR-2682-5p	PAR-CLIP	22291592
MIRT496232	hsa-miR-34b-5p	PAR-CLIP	22291592
MIRT496231	hsa-miR-449c-5p	PAR-CLIP	22291592
MIRT496230	hsa-miR-3976	PAR-CLIP	22291592
MIRT496229	hsa-miR-1295b-3p	PAR-CLIP	22291592
MIRT515447	hsa-miR-548av-5p	PAR-CLIP	23446348
MIRT515446	hsa-miR-548k	PAR-CLIP	23446348
MIRT515444	hsa-miR-8054	PAR-CLIP	23446348
MIRT515445	hsa-miR-1278	PAR-CLIP	23446348
MIRT515443	hsa-miR-556-5p	PAR-CLIP	23446348
MIRT515441	hsa-miR-3973	PAR-CLIP	23446348
MIRT515442	hsa-miR-186-3p	PAR-CLIP	23446348
MIRT515440	hsa-miR-619-5p	PAR-CLIP	23446348
MIRT515439	hsa-miR-6506-5p	PAR-CLIP	23446348
MIRT515438	hsa-miR-610	PAR-CLIP	23446348
MIRT515437	hsa-miR-6511b-5p	PAR-CLIP	23446348
MIRT515436	hsa-miR-6811-5p	PAR-CLIP	23446348
MIRT515434	hsa-miR-5089-5p	PAR-CLIP	23446348
MIRT496239	hsa-miR-6858-3p	PAR-CLIP	22291592
MIRT496238	hsa-miR-1910-3p	PAR-CLIP	22291592
MIRT496237	hsa-miR-6511a-5p	PAR-CLIP	22291592
MIRT496236	hsa-miR-6808-5p	PAR-CLIP	22291592
MIRT496235	hsa-miR-6893-5p	PAR-CLIP	22291592
MIRT496234	hsa-miR-940	PAR-CLIP	22291592
MIRT496233	hsa-miR-2682-5p	PAR-CLIP	22291592
MIRT496232	hsa-miR-34b-5p	PAR-CLIP	22291592
MIRT496231	hsa-miR-449c-5p	PAR-CLIP	22291592
MIRT496230	hsa-miR-3976	PAR-CLIP	22291592
MIRT496229	hsa-miR-1295b-3p	PAR-CLIP	22291592
MIRT1456113	hsa-miR-150	CLIP-seq
MIRT1456114	hsa-miR-4757-5p	CLIP-seq
MIRT2136709	hsa-miR-4694-5p	CLIP-seq

Gene ontology (GO) Show/Hide all (7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 32296183, 32814053
GO:0005737	Component	Cytoplasm	IBA
GO:0005829	Component	Cytosol	IDA
GO:0008270	Function	Zinc ion binding	IEA
GO:0045087	Process	Innate immune response	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:0061630	Function	Ubiquitin protein ligase activity	IBA

Other IDs

• MIM: 612550
• HGNC: 17453
• e!Ensembl: ENSG00000155428

Protein

• UniProt ID: Q86UV6
• Protein name: Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00643	zf-B_box	84 → 125	B-box zinc finger	Domain
  PF13445	zf-RING_UBOX	16 → 54	RING-type zinc-finger	Domain

• Sequence:

  MAWQVSLLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV
  DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH
  PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ
  ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF
  IWKFHSMASR

• Sequence length: 250

Related Genes

No strongly related genes found yet for TRIM74.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to TRIM74.