TRIM49B (tripartite motif containing 49B)

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Gene Gene information from NCBI Gene database.
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Entrez ID 283116
Gene name Tripartite motif containing 49B
Gene symbol TRIM49B
Synonyms (NCBI Gene)
-
Chromosome 11
Chromosome location 11p11.12
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6 Show/Hide all (6)
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GO ID Ontology Definition Evidence Reference
GO:0005737 Component Cytoplasm IBA
GO:0008270 Function Zinc ion binding IEA
GO:0010468 Process Regulation of gene expression IBA
GO:0045087 Process Innate immune response IBA
GO:0046872 Function Metal ion binding IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
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UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
A6NDI0
Protein name Putative tripartite motif-containing protein 49B (RING finger protein 18B)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00622 SPRY 340 → 451 SPRY domain Family
PF00643 zf-B_box 88 → 129 B-box zinc finger Domain
PF15227 zf-C3HC4_4 15 → 55 Domain
Sequence 
MNSGILQVFQRELICPICMNYFIDPVTIDCGHSFCRPCFYLNWKDSPFLVQCSECTKSTG
QINLKTNIHFKKMASLARKVSLWLFLSSEEQMCGTHRETKKMFCEVDRSLLCLLCSSSQE
HRDHRHCPIESAAEEHQEKLLQKMQSLWEKACENHRNLNVETTRTRCWKDYVNLRLEAIR
AEYQKMPAFHHEEEKHNLEMLKKKGKDIFHRLHLSKAKMAHRREILRGMYEELNEMCHKP
DVELLQAFGDILHRSESVLLHMPQPLNPELSAGPITGLRDRLNQFRVHITLHHEEANSDI
FLCEILRSMCIGCDHQDVPYFTATPRSFLAWGAQTFTSGKYYWEVHVGDSWNWAFGVCNM
YWKEKNQNEKIDGEDGLFLLGCVKNDIQRSLFTTSPLLLQYIPRPTSRVGLFLDCEAKTV
SFVDVNQSSLIYTIPNCSFSPPLRPIFCCIHF
Sequence length 452
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
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Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Reference Evidence Score
CHRONIC KIDNEY DISEASE — GWAS catalog 31152163
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Kidney Failure, Chronic Kidney Failure GWASCAT_DG 31152163
★★★★★
★☆☆☆☆
Found in Text Mining only

No strongly related genes found yet for TRIM49B.

No additional diseases found yet through genes similar to TRIM49B.