TRIM43 (tripartite motif containing 43)

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Gene Gene information from NCBI Gene database.
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Entrez ID 129868
Gene name Tripartite motif containing 43
Gene symbol TRIM43
Synonyms (NCBI Gene)
TRIM43A
Chromosome 2
Chromosome location 2q11.1
miRNA miRNA information provided by mirtarbase database.
4
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miRTarBase ID miRNA Experiments Reference
MIRT1454832 hsa-miR-3149 CLIP-seq
MIRT1454833 hsa-miR-3179 CLIP-seq
MIRT1454834 hsa-miR-421 CLIP-seq
MIRT1454835 hsa-miR-4709-5p CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956, 32296183, 32814053
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IEA
GO:0005813 Component Centrosome IEA
GO:0005856 Component Cytoskeleton IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
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UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96BQ3
Protein name Tripartite motif-containing protein 43
Protein function E3 ligase that regulates nuclear lamina integrity and the association of viral chromatin with transcriptionally-active host chromatin. Acts thereby as a herpesvirus-specific antiviral factor and mediates the ubiquitination-dependent proteasomal
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00622 SPRY 336 → 446 SPRY domain Family
PF15227 zf-C3HC4_4 15 → 55 Domain
Sequence 
MDSDFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSP
KMDFKTNILLKNLVTIARKASLWQFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQE
HGAHKHHPIEEAAEEHREKLLKQMRILWKKIQENQRNLYEEGRTAFLWRGNVVLRAQMIR
NEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKP
DVELLQDLGDIVARSESVLLHMPQPVNPELTAGPITGLVYRLNRFRVEISFHFEVTNHNI
RLFEDVRSWMFRRGPLNSDRSDYFAAWGARVFSFGKHYWELDVDNSCDWALGVCNNSWIR
KNSTMVNSEDIFLLLCLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVT
KSSLIWSYPAGSLTFPVRPFFYTGHR
Sequence length 446
Interactions View interactions

No strongly related genes found yet for TRIM43.

No additional diseases found yet through genes similar to TRIM43.