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Gene Gene information from NCBI Gene database.
Entrez ID 51499
Gene name TP53 regulated inhibitor of apoptosis 1
Gene symbol TRIAP1
Synonyms (NCBI Gene)
HSPC132MDM35P53CSVWF-1
Chromosome 12
Chromosome location 12q24.31
miRNA miRNA information provided by mirtarbase database.
602 Show/Hide all (602)
miRTarBase ID miRNA Experiments Reference
MIRT546177 hsa-miR-548c-3p PAR-CLIP 21572407
MIRT546176 hsa-miR-548n PAR-CLIP 21572407
MIRT546174 hsa-miR-548az-5p PAR-CLIP 21572407
MIRT546175 hsa-miR-548t-5p PAR-CLIP 21572407
MIRT546173 hsa-miR-595 PAR-CLIP 21572407
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
28 Show/Hide all (28)
GO ID Ontology Definition Evidence Reference
GO:0002039 Function P53 binding IPI 15735003
GO:0005515 Function Protein binding IPI 15735003, 23931759, 26071602, 27499296, 28514442, 32296183, 33961781
GO:0005634 Component Nucleus IBA
GO:0005654 Component Nucleoplasm IDA
GO:0005739 Component Mitochondrion HTP 34800366
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
614943 26937 ENSG00000170855
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O43715
Protein name TP53-regulated inhibitor of apoptosis 1 (Protein 15E1.1) (WF-1) (p53-inducible cell-survival factor) (p53CSV)
Protein function Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes
PDB 4XZS , 4XZV , 6I3V , 6I3Y , 6I4Y , 8AG0
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05254 UPF0203 2 → 65 Uncharacterised protein family (UPF0203) Family
Sequence
Sequence length 76
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release