TREML4 (triggering receptor expressed on myeloid cells like 4)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 285852
• Gene name: Triggering receptor expressed on myeloid cells like 4
• Gene symbol: TREML4
• Synonyms (NCBI Gene): TLT-4, TLT4
• Chromosome: 6
• Chromosome location: 6p21.1

miRNA Show/Hide all (38)

miRTarBase ID	miRNA	Experiments	Reference
MIRT1452435	hsa-miR-145	CLIP-seq
MIRT1452436	hsa-miR-2115	CLIP-seq
MIRT1452437	hsa-miR-3150a-3p	CLIP-seq
MIRT1452438	hsa-miR-3151	CLIP-seq
MIRT1452439	hsa-miR-3173-3p	CLIP-seq
MIRT1452440	hsa-miR-3175	CLIP-seq
MIRT1452441	hsa-miR-3689d	CLIP-seq
MIRT1452442	hsa-miR-3690	CLIP-seq
MIRT1452443	hsa-miR-370	CLIP-seq
MIRT1452444	hsa-miR-3920	CLIP-seq
MIRT1452445	hsa-miR-3942-5p	CLIP-seq
MIRT1452446	hsa-miR-4254	CLIP-seq
MIRT1452447	hsa-miR-4457	CLIP-seq
MIRT1452448	hsa-miR-4663	CLIP-seq
MIRT1452449	hsa-miR-4703-5p	CLIP-seq
MIRT1452450	hsa-miR-4713-3p	CLIP-seq
MIRT1452451	hsa-miR-491-5p	CLIP-seq
MIRT1452452	hsa-miR-513b	CLIP-seq
MIRT1452453	hsa-miR-622	CLIP-seq
MIRT1452454	hsa-miR-769-5p	CLIP-seq
MIRT1452455	hsa-miR-939	CLIP-seq
MIRT1452443	hsa-miR-370	CLIP-seq
MIRT2135481	hsa-miR-4259	CLIP-seq
MIRT1452448	hsa-miR-4663	CLIP-seq
MIRT2135482	hsa-miR-4715-5p	CLIP-seq
MIRT1452454	hsa-miR-769-5p	CLIP-seq
MIRT2356623	hsa-miR-1285	CLIP-seq
MIRT2356624	hsa-miR-2117	CLIP-seq
MIRT2356625	hsa-miR-3127-5p	CLIP-seq
MIRT2356626	hsa-miR-3187-5p	CLIP-seq
MIRT2356627	hsa-miR-4656	CLIP-seq
MIRT1452448	hsa-miR-4663	CLIP-seq
MIRT2356628	hsa-miR-4766-5p	CLIP-seq
MIRT2356629	hsa-miR-4768-5p	CLIP-seq
MIRT2356630	hsa-miR-612	CLIP-seq
MIRT1452443	hsa-miR-370	CLIP-seq
MIRT1452448	hsa-miR-4663	CLIP-seq
MIRT1452454	hsa-miR-769-5p	CLIP-seq

Gene ontology (GO) Show/Hide all (8)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002376	Process	Immune system process	IEA
GO:0005576	Component	Extracellular region	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0009986	Component	Cell surface	IBA
GO:0034157	Process	Positive regulation of toll-like receptor 7 signaling pathway	IBA
GO:0034157	Process	Positive regulation of toll-like receptor 7 signaling pathway	IMP	25848864
GO:0038023	Function	Signaling receptor activity	IBA
GO:0045087	Process	Innate immune response	IEA

Other IDs

• MIM: 614664
• HGNC: 30807
• e!Ensembl: ENSG00000188056

Protein

• UniProt ID: Q6UXN2
• Protein name: Trem-like transcript 4 protein (TLT-4) (Triggering receptor expressed on myeloid cells-like protein 4)
• Protein function: Positively regulates Toll-like receptor TLR7 signaling in macrophages.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07686	V-set	23 → 130	Immunoglobulin V-set domain	Domain

• Sequence:

  MAWGGVHTCCFHLCCCCSWPQGAVPEELHKHPGQTLLLQCQYSPKRGPYQPKSWCQQTSP
  SRCTLLVTSSKPWTAVQKSHYTIWDKPNAGFFNITMIQLTQNDSGFYWCGIYNASENIIT
  VLRNISLVVSPAPTTSPMWTLPWLPTSTVLITSPEGTSGHPSINGSETRKSRAPACLGSG
  GPRFLVLVLCGLLLAKGLML

• Sequence length: 200

Pathways

Reactome Pathway:

Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Related Genes

No strongly related genes found yet for TREML4.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to TREML4.