TRAV22 (T cell receptor alpha variable 22)

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Gene Gene information from NCBI Gene database.
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Entrez ID 28661
Gene name T cell receptor alpha variable 22
Gene symbol TRAV22
Synonyms (NCBI Gene)
TCRAV13S1TCRAV22S1
Chromosome 14
Chromosome location 14q11.2
Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha
miRNA miRNA information provided by mirtarbase database.
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miRTarBase ID miRNA Experiments Reference
MIRT016835 hsa-miR-335-5p Microarray 18185580
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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GO ID Ontology Definition Evidence Reference
GO:0002250 Process Adaptive immune response IEA
GO:0002376 Process Immune system process IEA
GO:0005886 Component Plasma membrane IEA
GO:0016020 Component Membrane IEA
GO:0042101 Component T cell receptor complex IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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MIM HGNC e!Ensembl
HGNC N/A TRAV22
Protein Protein information from UniProt database.
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UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
A0A0B4J277
Protein name T cell receptor alpha variable 22
Protein function V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are pre
PDB 4UDT , 4UDU , 5FK9 , 5FKA , 5MEN , 6R2L
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07686 V-set 26 → 110 Immunoglobulin V-set domain Domain
Sequence 
MKRILGALLGLLSAQVCCVRGIQVEQSPPDLILQEGANSTLRCNFSDSVNNLQWFHQNPW
GQLINLFYIPSGTKQNGRLSATTVATERYSLLYISSSQTTDSGVYFCAVE
Sequence length 110
Interactions View interactions

No strongly related genes found yet for TRAV22.

No additional diseases found yet through genes similar to TRAV22.