TRAV12-3 (T cell receptor alpha variable 12-3)

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Gene Gene information from NCBI Gene database.
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Entrez ID 28672
Gene name T cell receptor alpha variable 12-3
Gene symbol TRAV12-3
Synonyms (NCBI Gene)
TCRAV12S3TCRAV2S2TRAV123
Chromosome 14
Chromosome location 14q11.2
Summary T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6 Show/Hide all (6)
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GO ID Ontology Definition Evidence Reference
GO:0002250 Process Adaptive immune response IEA
GO:0002376 Process Immune system process IEA
GO:0005886 Component Plasma membrane IEA
GO:0016020 Component Membrane IEA
GO:0042101 Component T cell receptor complex IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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MIM HGNC e!Ensembl
HGNC N/A TRAV12-3
Protein Protein information from UniProt database.
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UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
A0A0B4J271
Protein name T cell receptor alpha variable 12-3
Protein function V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are pre
PDB 4WWK , 5C07 , 5C08 , 5C09 , 5C0A , 5C0B , 5C0C , 5HYJ , 6JXR , 7FJD , 7FJE , 7FJF
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07686 V-set 28 → 114 Immunoglobulin V-set domain Domain
Sequence 
MMKSLRVLLVILWLQLSWVWSQQKEVEQDPGPLSVPEGAIVSLNCTYSNSAFQYFMWYRQ
YSRKGPELLMYTYSSGNKEDGRFTAQVDKSSKYISLFIRDSQPSDSATYLCAMS
Sequence length 114
Interactions View interactions

No strongly related genes found yet for TRAV12-3.

No additional diseases found yet through genes similar to TRAV12-3.