TPGS1 (tubulin polyglutamylase complex subunit 1)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 91978
• Gene name: Tubulin polyglutamylase complex subunit 1
• Gene symbol: TPGS1
• Synonyms (NCBI Gene): C19orf20, GTRGEO22, PGs1
• Chromosome: 19
• Chromosome location: 19p13.3

miRNA Show/Hide all (77)

miRTarBase ID	miRNA	Experiments	Reference
MIRT693445	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT693444	hsa-miR-6501-3p	HITS-CLIP	23313552
MIRT693443	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT693442	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT693441	hsa-miR-6742-3p	HITS-CLIP	23313552
MIRT693440	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT693439	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT693438	hsa-miR-6776-5p	HITS-CLIP	23313552
MIRT693437	hsa-miR-4252	HITS-CLIP	23313552
MIRT693436	hsa-miR-661	HITS-CLIP	23313552
MIRT693435	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT693434	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT693433	hsa-miR-7703	HITS-CLIP	23313552
MIRT663332	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT663331	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT663330	hsa-miR-5193	HITS-CLIP	23824327
MIRT663329	hsa-miR-1281	HITS-CLIP	23824327
MIRT663328	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT663327	hsa-miR-1250-5p	HITS-CLIP	23824327
MIRT663326	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT663325	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT663324	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT663323	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT663322	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT663321	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT615693	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT615692	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT615693	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT615692	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT615693	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT615692	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT615693	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT615692	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT615693	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT615692	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT615693	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT615692	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT693442	hsa-miR-6849-3p	PAR-CLIP	27292025
MIRT693442	hsa-miR-6849-3p	PAR-CLIP	27292025
MIRT693442	hsa-miR-6849-3p	PAR-CLIP	27292025
MIRT693445	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT693444	hsa-miR-6501-3p	HITS-CLIP	23313552
MIRT693443	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT693442	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT693441	hsa-miR-6742-3p	HITS-CLIP	23313552
MIRT693440	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT693439	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT693438	hsa-miR-6776-5p	HITS-CLIP	23313552
MIRT693437	hsa-miR-4252	HITS-CLIP	23313552
MIRT693436	hsa-miR-661	HITS-CLIP	23313552
MIRT693435	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT693434	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT693433	hsa-miR-7703	HITS-CLIP	23313552
MIRT663332	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT663331	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT663330	hsa-miR-5193	HITS-CLIP	23824327
MIRT663329	hsa-miR-1281	HITS-CLIP	23824327
MIRT663328	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT663327	hsa-miR-1250-5p	HITS-CLIP	23824327
MIRT663326	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT663325	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT663324	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT663323	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT663322	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT663321	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT615693	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT615692	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT615693	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT615692	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT615693	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT615692	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT615693	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT615692	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT615693	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT615692	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT615693	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT615692	hsa-miR-208b-5p	HITS-CLIP	23824327

Gene ontology (GO) Show/Hide all (28)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000226	Process	Microtubule cytoskeleton organization	IDA	34782749
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA	21399614
GO:0005813	Component	Centrosome	IEA
GO:0005815	Component	Microtubule organizing center	IBA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IEA
GO:0005929	Component	Cilium	IEA
GO:0007268	Process	Chemical synaptic transmission	IEA
GO:0007283	Process	Spermatogenesis	IEA
GO:0007288	Process	Sperm axoneme assembly	IBA
GO:0007288	Process	Sperm axoneme assembly	IEA
GO:0008017	Function	Microtubule binding	IBA
GO:0008017	Function	Microtubule binding	IEA
GO:0015631	Function	Tubulin binding	IEA
GO:0030154	Process	Cell differentiation	IEA
GO:0030424	Component	Axon	IEA
GO:0030425	Component	Dendrite	IEA
GO:0030534	Process	Adult behavior	IEA
GO:0031514	Component	Motile cilium	IEA
GO:0034451	Component	Centriolar satellite	IEA
GO:0042995	Component	Cell projection	IEA
GO:0045202	Component	Synapse	IEA
GO:0046785	Process	Microtubule polymerization	IDA	10791892, 34782749
GO:0051648	Process	Vesicle localization	IEA
GO:0061523	Process	Cilium disassembly	IDA	34782749
GO:0070740	Function	Tubulin-glutamic acid ligase activity	IBA
GO:0070740	Function	Tubulin-glutamic acid ligase activity	IEA

Other IDs

• MIM: 620709
• HGNC: 25058
• e!Ensembl: ENSG00000141933

Protein

• UniProt ID: Q6ZTW0
• Protein name: Tubulin polyglutamylase complex subunit 1 (PGs1)
• Protein function: Subunit of the tubulin polyglutamylase complex (TPGC). The complex mediates cilia and flagella polyglutamylation which is essential for their biogenesis and motility (Probable). May act in the targeting of the tubulin polyglutamylase complex. Re
• Sequence:

  MAAVEKRRQAVPPPAGFTDSGRQSVSRAAGAAESEEDFLRQVGVTEMLRAALLKVLEARP
  EEPIAFLAHYFENMGLRSPVNGGAGEPPGQLLLQQQRLGRALWHLRLAHHSQRAAFNNNV
  SVAYECLSAGGRRKRPGLDGRTYSELLRRICRDGQAPEEVVAPLLRKVQCRDHEAVPLSV
  FRAGTLTCFVLLEFVARAGALFQLLEDSAAAVADRRVGQAVLDTLEGALQASDAAAPARF
  LEAGSRLGPDSLALALDRAVGGRRPSAPMTREEFLERAAALFIAKVKPVG

• Sequence length: 290

Related Genes

No strongly related genes found yet for TPGS1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to TPGS1.