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Gene Gene information from NCBI Gene database.
Entrez ID 58476
Gene name Tumor protein p53 inducible nuclear protein 2
Gene symbol TP53INP2
Synonyms (NCBI Gene)
C20orf110DORPIG-UPIGUPINHdJ1181N3.1
Chromosome 20
Chromosome location 20q11.22
Summary The protein encoded by this gene promotes autophagy and is essential for proper autophagosome formation and processing. In addition, the encoded protein can enhance rDNA transcription by helping in the assembly of the POLR1/RNA polymerase I preinitiation
miRNA miRNA information provided by mirtarbase database.
921 Show/Hide all (921)
miRTarBase ID miRNA Experiments Reference
MIRT053399 hsa-miR-629-5p Microarray 23807165
MIRT722074 hsa-miR-128-3p HITS-CLIP 19536157
MIRT722073 hsa-miR-216a-3p HITS-CLIP 19536157
MIRT722072 hsa-miR-3681-3p HITS-CLIP 19536157
MIRT722071 hsa-miR-1910-5p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
24 Show/Hide all (24)
GO ID Ontology Definition Evidence Reference
GO:0000045 Process Autophagosome assembly IBA
GO:0000045 Process Autophagosome assembly IDA 19056683
GO:0001649 Process Osteoblast differentiation IEA
GO:0001894 Process Tissue homeostasis IEA
GO:0005515 Function Protein binding IPI 19056683, 22470510
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
617549 16104 ENSG00000078804
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8IXH6
Protein name Tumor protein p53-inducible nuclear protein 2 (Diabetes and obesity-regulated gene) (p53-inducible protein U) (PIG-U)
Protein function Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophag
PDB 7YO9 , 8T31 , 8T32 , 8T33 , 8T35 , 8T36 , 8T4T
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF14839 DOR 48 → 216 DOR family Family
Sequence
Sequence length 220
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway
Autophagy - animal