Log in to bookmark this gene

Bookmark This Gene

Gene Gene information from NCBI Gene database.
Entrez ID 10953
Gene name Translocase of outer mitochondrial membrane 34
Gene symbol TOMM34
Synonyms (NCBI Gene)
HTOM34PTOM34URCC3
Chromosome 20
Chromosome location 20q13.12
Summary The protein encoded by this gene is involved in the import of precursor proteins into mitochondria. The encoded protein has a chaperone-like activity, binding the mature portion of unfolded proteins and aiding their import into mitochondria. This protein,
miRNA miRNA information provided by mirtarbase database.
186 Show/Hide all (186)
miRTarBase ID miRNA Experiments Reference
MIRT001404 hsa-miR-16-5p pSILAC 18668040
MIRT020702 hsa-miR-155-5p Proteomics 18668040
MIRT022511 hsa-miR-124-3p Microarray 18668037
MIRT030429 hsa-miR-24-3p Microarray 19748357
MIRT001404 hsa-miR-16-5p Microarray 21199864
Transcription factors Transcription factors information provided by TRRUST V2 database.
1
Transcription factor Regulation Reference
NRF1 Unknown 18364745
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
18 Show/Hide all (18)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 21044950
GO:0005634 Component Nucleus HDA 21630459
GO:0005737 Component Cytoplasm IEA
GO:0005739 Component Mitochondrion HTP 34800366
GO:0005739 Component Mitochondrion IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
616049 15746 ENSG00000025772
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q15785
Protein name Mitochondrial import receptor subunit TOM34 (hTom34) (Translocase of outer membrane 34 kDa subunit)
Protein function Plays a role in the import of cytosolically synthesized preproteins into mitochondria. Binds the mature portion of precursor proteins. Interacts with cellular components, and possesses weak ATPase activity. May be a chaperone-like protein that h
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00515 TPR_1 227 → 260 Tetratricopeptide repeat Repeat
Tissue specificity TISSUE SPECIFICITY: Ubiquitous.
Sequence
MAPKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAAC
HLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTS
AVEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTAT
KNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVL
KQYTEAVKDCTEALKLDGKN
VKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKL
RQEVKQNLH
Sequence length 309
Interactions View interactions