TMEM81 (transmembrane protein 81)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 388730
• Gene name: Transmembrane protein 81
• Gene symbol: TMEM81
• Synonyms (NCBI Gene): HC3107, KVLA2788, UNQ2788
• Chromosome: 1
• Chromosome location: 1q32.1

miRNA Show/Hide all (114)

miRTarBase ID	miRNA	Experiments	Reference
MIRT025833	hsa-miR-7-5p	Microarray	17612493
MIRT713748	hsa-miR-548b-3p	HITS-CLIP	19536157
MIRT713747	hsa-miR-3974	HITS-CLIP	19536157
MIRT713746	hsa-miR-624-3p	HITS-CLIP	19536157
MIRT713745	hsa-miR-4457	HITS-CLIP	19536157
MIRT713744	hsa-miR-125b-2-3p	HITS-CLIP	19536157
MIRT713743	hsa-miR-513b-5p	HITS-CLIP	19536157
MIRT713742	hsa-miR-5096	HITS-CLIP	19536157
MIRT713741	hsa-miR-335-3p	HITS-CLIP	19536157
MIRT544327	hsa-miR-1285-5p	PAR-CLIP	20371350
MIRT544326	hsa-miR-218-2-3p	PAR-CLIP	20371350
MIRT544325	hsa-miR-1324	PAR-CLIP	20371350
MIRT544324	hsa-miR-4330	PAR-CLIP	20371350
MIRT544323	hsa-miR-8069	PAR-CLIP	20371350
MIRT544322	hsa-miR-218-1-3p	PAR-CLIP	20371350
MIRT544321	hsa-miR-3692-3p	PAR-CLIP	20371350
MIRT544327	hsa-miR-1285-5p	PAR-CLIP	21572407
MIRT544326	hsa-miR-218-2-3p	PAR-CLIP	21572407
MIRT544325	hsa-miR-1324	PAR-CLIP	21572407
MIRT544324	hsa-miR-4330	PAR-CLIP	21572407
MIRT544323	hsa-miR-8069	PAR-CLIP	21572407
MIRT544322	hsa-miR-218-1-3p	PAR-CLIP	21572407
MIRT544321	hsa-miR-3692-3p	PAR-CLIP	21572407
MIRT496345	hsa-miR-6801-3p	PAR-CLIP	22291592
MIRT496344	hsa-miR-6810-3p	PAR-CLIP	22291592
MIRT496343	hsa-miR-6752-3p	PAR-CLIP	22291592
MIRT496342	hsa-miR-4722-3p	PAR-CLIP	22291592
MIRT496341	hsa-miR-6727-3p	PAR-CLIP	22291592
MIRT496340	hsa-miR-4769-3p	PAR-CLIP	22291592
MIRT496339	hsa-miR-6817-5p	PAR-CLIP	22291592
MIRT496338	hsa-miR-5590-5p	PAR-CLIP	22291592
MIRT496337	hsa-miR-6793-3p	PAR-CLIP	22291592
MIRT456456	hsa-miR-4694-3p	PAR-CLIP	23592263
MIRT456455	hsa-miR-5197-3p	PAR-CLIP	23592263
MIRT456453	hsa-miR-6854-5p	PAR-CLIP	23592263
MIRT456454	hsa-miR-6783-5p	PAR-CLIP	23592263
MIRT456452	hsa-miR-4802-5p	PAR-CLIP	23592263
MIRT456451	hsa-miR-3691-3p	PAR-CLIP	23592263
MIRT456450	hsa-miR-6134	PAR-CLIP	23592263
MIRT456449	hsa-miR-5093	PAR-CLIP	23592263
MIRT456448	hsa-miR-3612	PAR-CLIP	23592263
MIRT456447	hsa-miR-650	PAR-CLIP	23592263
MIRT456446	hsa-miR-3689d	PAR-CLIP	23592263
MIRT456445	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT456444	hsa-miR-3175	PAR-CLIP	23592263
MIRT456443	hsa-miR-1343-5p	PAR-CLIP	23592263
MIRT456442	hsa-miR-939-5p	PAR-CLIP	23592263
MIRT456441	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT456440	hsa-miR-92a-2-5p	PAR-CLIP	23592263
MIRT456439	hsa-miR-491-5p	PAR-CLIP	23592263
MIRT456438	hsa-miR-3150a-3p	PAR-CLIP	23592263
MIRT456437	hsa-miR-6763-5p	PAR-CLIP	23592263
MIRT713748	hsa-miR-548b-3p	HITS-CLIP	19536157
MIRT713747	hsa-miR-3974	HITS-CLIP	19536157
MIRT713746	hsa-miR-624-3p	HITS-CLIP	19536157
MIRT713745	hsa-miR-4457	HITS-CLIP	19536157
MIRT713744	hsa-miR-125b-2-3p	HITS-CLIP	19536157
MIRT713743	hsa-miR-513b-5p	HITS-CLIP	19536157
MIRT713742	hsa-miR-5096	HITS-CLIP	19536157
MIRT713741	hsa-miR-335-3p	HITS-CLIP	19536157
MIRT544327	hsa-miR-1285-5p	PAR-CLIP	20371350
MIRT544326	hsa-miR-218-2-3p	PAR-CLIP	20371350
MIRT544325	hsa-miR-1324	PAR-CLIP	20371350
MIRT544324	hsa-miR-4330	PAR-CLIP	20371350
MIRT544323	hsa-miR-8069	PAR-CLIP	20371350
MIRT544322	hsa-miR-218-1-3p	PAR-CLIP	20371350
MIRT544321	hsa-miR-3692-3p	PAR-CLIP	20371350
MIRT544327	hsa-miR-1285-5p	PAR-CLIP	21572407
MIRT544326	hsa-miR-218-2-3p	PAR-CLIP	21572407
MIRT544325	hsa-miR-1324	PAR-CLIP	21572407
MIRT544324	hsa-miR-4330	PAR-CLIP	21572407
MIRT544323	hsa-miR-8069	PAR-CLIP	21572407
MIRT544322	hsa-miR-218-1-3p	PAR-CLIP	21572407
MIRT544321	hsa-miR-3692-3p	PAR-CLIP	21572407
MIRT496345	hsa-miR-6801-3p	PAR-CLIP	22291592
MIRT496344	hsa-miR-6810-3p	PAR-CLIP	22291592
MIRT496343	hsa-miR-6752-3p	PAR-CLIP	22291592
MIRT496342	hsa-miR-4722-3p	PAR-CLIP	22291592
MIRT496341	hsa-miR-6727-3p	PAR-CLIP	22291592
MIRT496340	hsa-miR-4769-3p	PAR-CLIP	22291592
MIRT496339	hsa-miR-6817-5p	PAR-CLIP	22291592
MIRT496338	hsa-miR-5590-5p	PAR-CLIP	22291592
MIRT496337	hsa-miR-6793-3p	PAR-CLIP	22291592
MIRT456456	hsa-miR-4694-3p	PAR-CLIP	23592263
MIRT456455	hsa-miR-5197-3p	PAR-CLIP	23592263
MIRT456453	hsa-miR-6854-5p	PAR-CLIP	23592263
MIRT456454	hsa-miR-6783-5p	PAR-CLIP	23592263
MIRT456452	hsa-miR-4802-5p	PAR-CLIP	23592263
MIRT456451	hsa-miR-3691-3p	PAR-CLIP	23592263
MIRT456450	hsa-miR-6134	PAR-CLIP	23592263
MIRT456449	hsa-miR-5093	PAR-CLIP	23592263
MIRT456448	hsa-miR-3612	PAR-CLIP	23592263
MIRT456447	hsa-miR-650	PAR-CLIP	23592263
MIRT456446	hsa-miR-3689d	PAR-CLIP	23592263
MIRT456445	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT456444	hsa-miR-3175	PAR-CLIP	23592263
MIRT456443	hsa-miR-1343-5p	PAR-CLIP	23592263
MIRT456442	hsa-miR-939-5p	PAR-CLIP	23592263
MIRT456441	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT456440	hsa-miR-92a-2-5p	PAR-CLIP	23592263
MIRT456439	hsa-miR-491-5p	PAR-CLIP	23592263
MIRT456438	hsa-miR-3150a-3p	PAR-CLIP	23592263
MIRT456437	hsa-miR-6763-5p	PAR-CLIP	23592263
MIRT2131513	hsa-miR-1236	CLIP-seq
MIRT2131514	hsa-miR-4680-5p	CLIP-seq
MIRT2131515	hsa-miR-873	CLIP-seq
MIRT2352788	hsa-miR-1207-3p	CLIP-seq
MIRT2352789	hsa-miR-1302	CLIP-seq
MIRT2352790	hsa-miR-154	CLIP-seq
MIRT2352791	hsa-miR-4298	CLIP-seq
MIRT2352792	hsa-miR-4530	CLIP-seq
MIRT2352793	hsa-miR-4670-3p	CLIP-seq
MIRT2352794	hsa-miR-634	CLIP-seq
MIRT2352795	hsa-miR-646	CLIP-seq

Gene ontology (GO) Show/Hide all (6)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005886	Component	Plasma membrane	IDA	39423812
GO:0005886	Component	Plasma membrane	IEA
GO:0016020	Component	Membrane	IEA
GO:0030674	Function	Protein-macromolecule adaptor activity	IDA	39423812
GO:0035036	Process	Sperm-egg recognition	IDA	39423812
GO:0035036	Process	Sperm-egg recognition	ISS

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q6P7N7
• Protein name: Transmembrane protein 81
• Protein function: Essential fertilization factor required for male fertility. Part of a conserved trimeric sperm complex with the essential fertilization factors IZUMO1 and SPACA6 which bridges sperm and oocyte membranes during fertilization by binding to IZUMO1R
• Tissue specificity: TISSUE SPECIFICITY: Highly expressed in sperm (at protein level). {ECO:0000269|PubMed:39423812}.
• Sequence:

  MKVLATSFVLGSLGLAFYLPLVVTTPKTLAIPEKLQEAVGKVIINATTCTVTCGLGYKEE
  TVCEVGPDGVRRKCQTRRLECLTNWICGMLHFTILIGKEFELSCLSSDILEFGQEAFRFT
  WRLARGVISTDDEVFKPFQANSHFVKFKYAQEYDSGTYRCDVQLVKNLRLVKRLYFGLRV
  LPPNLVNLNFHQSLTEDQKLIDEGLEVNLDSYSKPHHPKWKKKVASALGIGIAIGVVGGV
  LVRIVLCALRGGLQQ

• Sequence length: 255

Related Genes

No strongly related genes found yet for TMEM81.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to TMEM81.