TMEM168 (transmembrane protein 168)

Download as csv Download as pdf

Log in to bookmark this gene

Bookmark This Gene

Title Project / Tag (optional) Note (optional)

Cancel Save

On this page

Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 64418
• Gene name: Transmembrane protein 168
• Gene symbol: TMEM168
• Synonyms (NCBI Gene): -
• Chromosome: 7
• Chromosome location: 7q31.1

miRNA Show/Hide all (252)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020118	hsa-miR-130b-3p	Sequencing	20371350
MIRT024146	hsa-miR-221-3p	Sequencing	20371350
MIRT027266	hsa-miR-101-3p	Sequencing	20371350
MIRT027960	hsa-miR-93-5p	Sequencing	20371350
MIRT028945	hsa-miR-26b-5p	Microarray	19088304
MIRT031501	hsa-miR-16-5p	Sequencing	20371350
MIRT665814	hsa-miR-216a-5p	HITS-CLIP	23824327
MIRT665812	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT665809	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT678576	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT665802	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT665814	hsa-miR-216a-5p	HITS-CLIP	23824327
MIRT665813	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT665812	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT665811	hsa-miR-5693	HITS-CLIP	23824327
MIRT665810	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT665809	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT665808	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT665807	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT665806	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT665805	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT665804	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT665803	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT665802	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT665801	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT665800	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT665799	hsa-miR-5698	HITS-CLIP	23824327
MIRT665814	hsa-miR-216a-5p	HITS-CLIP	23824327
MIRT665812	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT665809	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT678576	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT665802	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT665814	hsa-miR-216a-5p	HITS-CLIP	23824327
MIRT665813	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT665812	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT665811	hsa-miR-5693	HITS-CLIP	23824327
MIRT665810	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT665809	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT665808	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT665807	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT665806	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT665805	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT665804	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT665803	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT665802	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT665801	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT665800	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT665799	hsa-miR-5698	HITS-CLIP	23824327
MIRT1432484	hsa-miR-1305	CLIP-seq
MIRT1432485	hsa-miR-199a-3p	CLIP-seq
MIRT1432486	hsa-miR-199b-3p	CLIP-seq
MIRT1432487	hsa-miR-2467-3p	CLIP-seq
MIRT1432488	hsa-miR-302f	CLIP-seq
MIRT1432489	hsa-miR-3129-5p	CLIP-seq
MIRT1432490	hsa-miR-3613-3p	CLIP-seq
MIRT1432491	hsa-miR-3678-3p	CLIP-seq
MIRT1432492	hsa-miR-4263	CLIP-seq
MIRT1432493	hsa-miR-452	CLIP-seq
MIRT1432494	hsa-miR-4639-5p	CLIP-seq
MIRT1432495	hsa-miR-4659a-3p	CLIP-seq
MIRT1432496	hsa-miR-4659b-3p	CLIP-seq
MIRT1432497	hsa-miR-4676-3p	CLIP-seq
MIRT1432498	hsa-miR-4693-3p	CLIP-seq
MIRT1432499	hsa-miR-4712-3p	CLIP-seq
MIRT1432500	hsa-miR-513a-3p	CLIP-seq
MIRT1432501	hsa-miR-539	CLIP-seq
MIRT1432502	hsa-miR-549	CLIP-seq
MIRT1432503	hsa-miR-576-5p	CLIP-seq
MIRT1432504	hsa-miR-591	CLIP-seq
MIRT1432505	hsa-miR-607	CLIP-seq
MIRT1432506	hsa-miR-7	CLIP-seq
MIRT1432507	hsa-miR-936	CLIP-seq
MIRT1920981	hsa-miR-4760-3p	CLIP-seq
MIRT1432504	hsa-miR-591	CLIP-seq
MIRT1920981	hsa-miR-4760-3p	CLIP-seq
MIRT1432504	hsa-miR-591	CLIP-seq
MIRT2129616	hsa-miR-101	CLIP-seq
MIRT2129617	hsa-miR-1226	CLIP-seq
MIRT2129618	hsa-miR-1297	CLIP-seq
MIRT1432484	hsa-miR-1305	CLIP-seq
MIRT2129619	hsa-miR-144	CLIP-seq
MIRT2129620	hsa-miR-224	CLIP-seq
MIRT2129621	hsa-miR-26a	CLIP-seq
MIRT2129622	hsa-miR-26b	CLIP-seq
MIRT2129623	hsa-miR-3134	CLIP-seq
MIRT2129624	hsa-miR-3617	CLIP-seq
MIRT2129625	hsa-miR-3714	CLIP-seq
MIRT2129626	hsa-miR-383	CLIP-seq
MIRT2129627	hsa-miR-3922-5p	CLIP-seq
MIRT2129628	hsa-miR-3927	CLIP-seq
MIRT2129629	hsa-miR-4427	CLIP-seq
MIRT2129630	hsa-miR-4465	CLIP-seq
MIRT2129631	hsa-miR-4490	CLIP-seq
MIRT2129632	hsa-miR-4534	CLIP-seq
MIRT2129633	hsa-miR-4650-3p	CLIP-seq
MIRT2129634	hsa-miR-4678	CLIP-seq
MIRT2129635	hsa-miR-4680-3p	CLIP-seq
MIRT2129636	hsa-miR-4733-3p	CLIP-seq
MIRT2129637	hsa-miR-4764-3p	CLIP-seq
MIRT2129638	hsa-miR-4775	CLIP-seq
MIRT2129639	hsa-miR-491-3p	CLIP-seq
MIRT2129640	hsa-miR-498	CLIP-seq
MIRT2129641	hsa-miR-522	CLIP-seq
MIRT2129642	hsa-miR-582-5p	CLIP-seq
MIRT2129643	hsa-miR-586	CLIP-seq
MIRT2129644	hsa-miR-590-3p	CLIP-seq
MIRT2129645	hsa-miR-641	CLIP-seq
MIRT2129617	hsa-miR-1226	CLIP-seq
MIRT2129618	hsa-miR-1297	CLIP-seq
MIRT2129620	hsa-miR-224	CLIP-seq
MIRT2129621	hsa-miR-26a	CLIP-seq
MIRT2129622	hsa-miR-26b	CLIP-seq
MIRT2129628	hsa-miR-3927	CLIP-seq
MIRT2351146	hsa-miR-4266	CLIP-seq
MIRT2129630	hsa-miR-4465	CLIP-seq
MIRT2129633	hsa-miR-4650-3p	CLIP-seq
MIRT2129636	hsa-miR-4733-3p	CLIP-seq
MIRT2351147	hsa-miR-4777-3p	CLIP-seq
MIRT2129640	hsa-miR-498	CLIP-seq
MIRT2129641	hsa-miR-522	CLIP-seq
MIRT1432506	hsa-miR-7	CLIP-seq
MIRT2129617	hsa-miR-1226	CLIP-seq
MIRT2129618	hsa-miR-1297	CLIP-seq
MIRT1432484	hsa-miR-1305	CLIP-seq
MIRT2644796	hsa-miR-181a	CLIP-seq
MIRT2644797	hsa-miR-181b	CLIP-seq
MIRT2644798	hsa-miR-181c	CLIP-seq
MIRT2644799	hsa-miR-181d	CLIP-seq
MIRT2644800	hsa-miR-186	CLIP-seq
MIRT2129620	hsa-miR-224	CLIP-seq
MIRT2129621	hsa-miR-26a	CLIP-seq
MIRT2129622	hsa-miR-26b	CLIP-seq
MIRT2644801	hsa-miR-30a	CLIP-seq
MIRT2644802	hsa-miR-30b	CLIP-seq
MIRT2644803	hsa-miR-30c	CLIP-seq
MIRT2644804	hsa-miR-30d	CLIP-seq
MIRT2644805	hsa-miR-30e	CLIP-seq
MIRT2644806	hsa-miR-3126-3p	CLIP-seq
MIRT2644807	hsa-miR-3148	CLIP-seq
MIRT2644808	hsa-miR-3162-3p	CLIP-seq
MIRT2644809	hsa-miR-3163	CLIP-seq
MIRT2644810	hsa-miR-3165	CLIP-seq
MIRT2644811	hsa-miR-3182	CLIP-seq
MIRT2644812	hsa-miR-340	CLIP-seq
MIRT2644813	hsa-miR-3607-3p	CLIP-seq
MIRT2644814	hsa-miR-3609	CLIP-seq
MIRT2644815	hsa-miR-3612	CLIP-seq
MIRT2644816	hsa-miR-3618	CLIP-seq
MIRT2644817	hsa-miR-3653	CLIP-seq
MIRT2644818	hsa-miR-3658	CLIP-seq
MIRT2644819	hsa-miR-3662	CLIP-seq
MIRT2644820	hsa-miR-3663-5p	CLIP-seq
MIRT2644821	hsa-miR-3686	CLIP-seq
MIRT2129625	hsa-miR-3714	CLIP-seq
MIRT2129626	hsa-miR-383	CLIP-seq
MIRT2129627	hsa-miR-3922-5p	CLIP-seq
MIRT2129628	hsa-miR-3927	CLIP-seq
MIRT2644822	hsa-miR-3978	CLIP-seq
MIRT2644823	hsa-miR-4262	CLIP-seq
MIRT2644824	hsa-miR-4307	CLIP-seq
MIRT2644825	hsa-miR-4443	CLIP-seq
MIRT2644826	hsa-miR-4446-5p	CLIP-seq
MIRT2129630	hsa-miR-4465	CLIP-seq
MIRT1432493	hsa-miR-452	CLIP-seq
MIRT2644827	hsa-miR-4522	CLIP-seq
MIRT2644828	hsa-miR-4528	CLIP-seq
MIRT2129633	hsa-miR-4650-3p	CLIP-seq
MIRT1432497	hsa-miR-4676-3p	CLIP-seq
MIRT2644829	hsa-miR-4684-5p	CLIP-seq
MIRT2129636	hsa-miR-4733-3p	CLIP-seq
MIRT2129638	hsa-miR-4775	CLIP-seq
MIRT2644830	hsa-miR-4778-3p	CLIP-seq
MIRT2129640	hsa-miR-498	CLIP-seq
MIRT2644831	hsa-miR-520g	CLIP-seq
MIRT2644832	hsa-miR-520h	CLIP-seq
MIRT2129641	hsa-miR-522	CLIP-seq
MIRT2644833	hsa-miR-548ah	CLIP-seq
MIRT2644834	hsa-miR-548g	CLIP-seq
MIRT2644835	hsa-miR-548n	CLIP-seq
MIRT2644836	hsa-miR-548t	CLIP-seq
MIRT2644837	hsa-miR-582-3p	CLIP-seq
MIRT2129644	hsa-miR-590-3p	CLIP-seq
MIRT2644838	hsa-miR-601	CLIP-seq
MIRT2644839	hsa-miR-614	CLIP-seq
MIRT2644840	hsa-miR-650	CLIP-seq
MIRT2129617	hsa-miR-1226	CLIP-seq
MIRT2693429	hsa-miR-1238	CLIP-seq
MIRT2129618	hsa-miR-1297	CLIP-seq
MIRT1432484	hsa-miR-1305	CLIP-seq
MIRT2644800	hsa-miR-186	CLIP-seq
MIRT2129620	hsa-miR-224	CLIP-seq
MIRT2693430	hsa-miR-2278	CLIP-seq
MIRT2693431	hsa-miR-2467-5p	CLIP-seq
MIRT2129621	hsa-miR-26a	CLIP-seq
MIRT2129622	hsa-miR-26b	CLIP-seq
MIRT2644801	hsa-miR-30a	CLIP-seq
MIRT2644802	hsa-miR-30b	CLIP-seq
MIRT2644803	hsa-miR-30c	CLIP-seq
MIRT2644804	hsa-miR-30d	CLIP-seq
MIRT2644805	hsa-miR-30e	CLIP-seq
MIRT2644807	hsa-miR-3148	CLIP-seq
MIRT2644808	hsa-miR-3162-3p	CLIP-seq
MIRT2644809	hsa-miR-3163	CLIP-seq
MIRT2644810	hsa-miR-3165	CLIP-seq
MIRT2644811	hsa-miR-3182	CLIP-seq
MIRT2693432	hsa-miR-3188	CLIP-seq
MIRT2644812	hsa-miR-340	CLIP-seq
MIRT2644813	hsa-miR-3607-3p	CLIP-seq
MIRT2644814	hsa-miR-3609	CLIP-seq
MIRT2644815	hsa-miR-3612	CLIP-seq
MIRT2644817	hsa-miR-3653	CLIP-seq
MIRT2644818	hsa-miR-3658	CLIP-seq
MIRT2644819	hsa-miR-3662	CLIP-seq
MIRT2644821	hsa-miR-3686	CLIP-seq
MIRT2129625	hsa-miR-3714	CLIP-seq
MIRT2129626	hsa-miR-383	CLIP-seq
MIRT2129627	hsa-miR-3922-5p	CLIP-seq
MIRT2129628	hsa-miR-3927	CLIP-seq
MIRT2693433	hsa-miR-3975	CLIP-seq
MIRT2644822	hsa-miR-3978	CLIP-seq
MIRT2693434	hsa-miR-4303	CLIP-seq
MIRT2644824	hsa-miR-4307	CLIP-seq
MIRT2644825	hsa-miR-4443	CLIP-seq
MIRT2644826	hsa-miR-4446-5p	CLIP-seq
MIRT2129630	hsa-miR-4465	CLIP-seq
MIRT1432493	hsa-miR-452	CLIP-seq
MIRT2644827	hsa-miR-4522	CLIP-seq
MIRT2644828	hsa-miR-4528	CLIP-seq
MIRT2693435	hsa-miR-4649-3p	CLIP-seq
MIRT2129633	hsa-miR-4650-3p	CLIP-seq
MIRT1432497	hsa-miR-4676-3p	CLIP-seq
MIRT2129636	hsa-miR-4733-3p	CLIP-seq
MIRT2693436	hsa-miR-4762-3p	CLIP-seq
MIRT2129637	hsa-miR-4764-3p	CLIP-seq
MIRT2129638	hsa-miR-4775	CLIP-seq
MIRT2644830	hsa-miR-4778-3p	CLIP-seq
MIRT2693437	hsa-miR-485-5p	CLIP-seq
MIRT2129640	hsa-miR-498	CLIP-seq
MIRT2644831	hsa-miR-520g	CLIP-seq
MIRT2644832	hsa-miR-520h	CLIP-seq
MIRT2129641	hsa-miR-522	CLIP-seq
MIRT2644833	hsa-miR-548ah	CLIP-seq
MIRT2644834	hsa-miR-548g	CLIP-seq
MIRT2644835	hsa-miR-548n	CLIP-seq
MIRT2644836	hsa-miR-548t	CLIP-seq
MIRT2693438	hsa-miR-548v	CLIP-seq
MIRT2693439	hsa-miR-562	CLIP-seq
MIRT2644837	hsa-miR-582-3p	CLIP-seq
MIRT2129644	hsa-miR-590-3p	CLIP-seq
MIRT2644839	hsa-miR-614	CLIP-seq
MIRT2693440	hsa-miR-646	CLIP-seq
MIRT2644840	hsa-miR-650	CLIP-seq

Gene ontology (GO) Show/Hide all (7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005634	Component	Nucleus	IEA
GO:0016020	Component	Membrane	IEA
GO:0017080	Function	Sodium channel regulator activity	IMP	32175648
GO:0030133	Component	Transport vesicle	IDA
GO:0031965	Component	Nuclear membrane	IDA	32175648
GO:0031965	Component	Nuclear membrane	IEA
GO:2000058	Process	Regulation of ubiquitin-dependent protein catabolic process	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q9H0V1
• Protein name: Transmembrane protein 168
• Protein function: Plays a key role in maintaining the cardiac electrical stability by modulating cell surface expression of SCN5A (PubMed:32175648). May play a role in the modulation of anxiety behavior by regulating GABAergic neuronal system in the nucleus accum
• Sequence:

  MCKSLRYCFSHCLYLAMTRLEEVNREVNMHSSVRYLGYLARINLLVAICLGLYVRWEKTA
  NSLILVIFILGLFVLGIASILYYYFSMEAASLSLSNLWFGFLLGLLCFLDNSSFKNDVKE
  ESTKYLLLTSIVLRILCSLVERISGYVRHRPTLLTTVEFLELVGFAIASTTMLVEKSLSV
  ILLVVALAMLIIDLRMKSFLAIPNLVIFAVLLFFSSLETPKNPIAFACFFICLITDPFLD
  IYFSGLSVTERWKPFLYRGRICRRLSVVFAGMIELTFFILSAFKLRDTHLWYFVIPGFSI
  FGIFWMICHIIFLLTLWGFHTKLNDCHKVYFTHRTDYNSLDRIMASKGMRHFCLISEQLV
  FFSLLATAILGAVSWQPTNGIFLSMFLIVLPLESMAHGLFHELGNCLGGTSVGYAIVIPT
  NFCSPDGQPTLLPPEHVQELNLRSTGMLNAIQRFFAYHMIETYGCDYSTSGLSFDTLHSK
  LKAFLELRTVDGPRHDTYILYYSGHTHGTGEWALAGGDTLRLDTLIEWWREKNGSFCSRL
  IIVLDSENSTPWVKEVRKINDQYIAVQGAELIKTVDIEEADPPQLGDFTKDWVEYNCNSS
  NNICWTEKGRTVKAVYGVSKRWSDYTLHLPTGSDVAKHWMLHFPRITYPLVHLANWLCGL
  NLFWICKTCFRCLKRLKMSWFLPTVLDTGQGFKLVKS

• Sequence length: 697

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Hepatocellular carcinoma	Uncertain significance	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Carcinogenesis	Carcinogenesis	Pubtator	30940290	Associate	★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	30940290	Associate	★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	30940290		★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for TMEM168.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to TMEM168.